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2366篇 您的检索式:作者名="JONES C R"
    题名 作者 年代 出处 被引量
1Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes显示文摘This review aims to outline the most up-to-date knowledge of pancreatic adenocarcinoma risk, diagnostics, treatment and outcomes, while identifying gaps that aim to stimulate further research in this understudied malignancy. Pancreatic adenocarcinoma is a lethal condition with a rising incidence, predicted to become the second leading cause of cancer death in some regions. It often presents at an advanced stage, which contributes to poor five-year survival rates of 2%-9%, ranking firmly last amongst all cancer sites in terms of prognostic outcomes for patients. Better understanding of the risk factors and symptoms associated with this disease is essential to inform both health professionals and the general population of potential preventive and/or early detection measures. The identification of high-risk patients who could benefit from screening to detect pre-malignant conditions such as pancreatic intraepithelial neoplasia, intraductal papillary mucinous neoplasms and mucinous cystic neoplasms is urgently required, however an acceptable screening test has yet to be identified. The management of pancreatic adenocarcinoma is evolving, with the introduction of new surgical techniques and medical therapies such as laparoscopic techniques and neo-adjuvant chemoradiotherapy, however this has only led to modest improvements in outcomes. The identification of novel biomarkers is desirable to move towards a precision medicine era, where pancreatic cancer therapy can be tailored to the individual patient, while unnecessary treatments that have negative consequences on quality of life could be prevented for others. Research efforts must also focus on the development of new agents and delivery systems. Overall, considerable progress is required to reduce the burden associated with pancreatic cancer. Recent, renewed efforts to fund large consortia and research into pancreatic adenocarcinoma are welcomed, but further streams will be necessary to facilitate the momentum needed to bring breakthroughs seen for other cancer sites.Andrew McGuigan Paul Kelly Richard C Turkington Claire Jones Helen G Coleman R Stephen McCain 2018World Journal of Gastroenterology2018,24,43:140
2Cyclooxygenase-2 and epithelial growth factor receptor up-regulation during progression of Barrett's esophagus to adenocarcinoma显示文摘瞄准:在整个 Barretts 食管的前进调查 cyclooxygenase-2 (COX-2 ) 和上皮的生长因素受体(EGFR ) 的表示() 。方法:COX-2 和 EGFR 蛋白质表情被使用免疫检测组织化学的方法。详细 cytomorphological 改变的 A 是坚定的。COX-2 和 EGFR 表示的区域被使用计算机成像系统确定。结果:COX-2 和 EGFR 的表情与前进一起增加了从到食管腺癌(EAC ) 。积极关联在 COX-2 表示和 EGFR 表示之间被发现。结论:COX-2 和 EGFR 可能在逐步的前进从是合作的到 EAC,从而导致致癌作用。Yan Li John M Wo Mukunda B Ray Whitney Jones Ruifeng R Su Susan Ellis Robert C G Martin 2006World Journal of Gastroenterology2006,12,6:14
3Intentional ingestions of foreign objects among prisoners: A review显示文摘The intentional ingestion of foreign objects(IIFO) is described more commonly in prison populations than in the general population, with an estimated annual incidence of 1 in 1900 inmates in our state correctional facilities. Incidents often involve ingestion of small metal objects(e.g., paperclips, razor blades) or other commonly available items like pens or eating utensils. Despite ingestion of relatively sharp objects, most episodes can be clinically managed with either observation or endoscopy. Surgery should be reserved for those with signs or symptoms of gastrointestinal perforation or obstruction. For those with a history of IIFO, efforts should focus on prevention of recurrenceas subsequent episodes are associated with higher morbidity, significant healthcare and security costs. The pattern of IIFO is often repetitive, with escalation both in frequency of ingestions and in number of items ingested. Little is known about successful prevention strategies, but efforts to monitor patients and provide psychiatric care are potential best-practice strategies. This article aims to provide state-of-the art review on the topic, followed by a set of basic recommendations.David C Evans Thomas R Wojda Christian D Jones Andrew J Otey Stanislaw P Stawicki 2015World Journal of Gastrointestinal Endoscopy2015,7,3:10
4柑桔黄龙病的鉴定和柯赫氏定理(英文)显示文摘黄龙(梢)病被认为是世界柑橘生产上的毁灭性病害已超过一个世纪,但该病害的病原学至今还没有清晰地建立起来。根据16S rRNA基因序列分析,一组被称为'Candidatus Liberibacter species'的难培养细菌被认为与黄龙病相关。然而,要确定'Ca.Liberibacter spp.'是黄龙病病原的柯赫氏定理并没有真正完成。令我们担忧的是,近年来有些文献频频指出'Ca.Liberibacter spp.'是黄龙病的病原,其实该细菌与柑橘寄主的直接病理反应还没有完全确定。我们建议,在黄龙病病原学清楚之前,文献报道在这方面需要有准确的阐述。Chen J Deng X Civerolo E L Lee R F Jones J B Zhou C Hartung J S Manjunath K L Brlansky R H 2011植物病理学报2011,41,2:10
5气力输送管道压降预测影响的数值模拟研究显示文摘气力输送管道压降的预测有利于合理设计供风系统。建立了一气力输送实验装置,对某些截面的压力进行了实验测试。运用CFD仿真软件Fluent,建立了3维气固两相湍动双流体压降预测模型,通过对该气力输送系统的水平弯管进行的仿真研究,得到了与实验结果吻合较好的模型,并运用该模型分析了几个主要参数对气力输送系统压降预测的影响。马爱纯 Williams R C 周孑民 Jones M G 2010武汉理工大学学报2010,32,23:9
6The genome sequence of the SARS-associated coronavirus显示文摘Marra M A Jones S J Astell C R 0,,:6
7欧洲鼻腔鼻窦解剖术语意见书(二)显示文摘2014年,Rhinology刊登了European Position Paper on the Anatomical Terminology of the Internal Nose and Paranasal Sinuses,对于认识鼻科解剖名词具有重要的普及意义。考虑到国内耳鼻喉科医师获取和阅读英文文献的能力有限,但是又急需及时掌握学科领域内解剖名词的表述,我们通过与Rhinology编辑部及作者联系征得同意,翻译而成《欧洲鼻腔鼻窦解剖术语规范意见书》(以下简称《意见书》)。《意见书》中的所有解剖名词同时参考国内《英汉汉英医学分科词典(耳鼻咽喉科学分册)》进行统一,对于《英汉汉英医学分科词典(耳鼻咽喉科学分册)》中没有提及的名词给出了相应的补充。希望《意见书》对国内耳鼻喉科医师掌握并规范应用鼻科名词提供参考。《中国眼耳鼻喉科杂志》从第17卷第2期开始以连载形式刊登《意见书》。王德辉 王德云 于华鹏 孙希才 李晗 刘琢扶 刘全 张焕康 Lund VJ Stammberger H Fokkens WJ Beale T Bernal-Sprekelsen M Eloy P Georgalas C Gerstenberger C Hellings PW Herman P Hosemann WG Jankowski R Jones N Jorissen M Leunig A Onerci M Rimmer J Rombaux P Simmen D Tomazic PV Tschabitscher M Welge-Luessen A 2017中国眼耳鼻喉科杂志2017,17,3:2
8Nutrient foraging traits in 10 co-occurring plant species of contrasting life forms显示文摘Einsmann J C Jones R H Mou P 1999The Journal of Ecology1999,87,:1
9Protein and humic acid adsorption on to hydrophilic membrane surfaces: effect of pH and ionic strength 显示文摘JONES K L O'MELIA C R 2000J Membrane Sci2000,165,1:1
10Risk factors for in situ cervical cancer: results from a case-control study显示文摘Jones C J Brinimi L A Hamman R F 1990Cancer Res1990,50,12:1
11Virus infection expands a biased subset of T ceils that bind tetrameric class I peptide complexes 显示文摘COLES R M JONES C M BROOKS A G 2003Eur J Immunol2003,33,6:1
12Thermal Properties of DMNB, A Detection Agent for Exploslves显示文摘JONES D E G LIGHTFOOT P D FOUCHARD R C 2002Thermochimic Acta2002,388,12:1
13The efficacy of spinosad against the western flower thrips,Frankliniella occidentalis,and its impact on associated biological control agents on greenhouse cucumbers in southern Ontario显示文摘Jones T Scott D C Harris R 2005Pest Manag Sci2005,61,:1
14Why do Some Countries Produce So Much More Output Per Worker than Others? 显示文摘HALL R JONES C 1999The Quarterly Journal of Economics1999,,1:1
15Information acquisition during deci- sion making processes: an exploratory study of decision roles in media selection 显示文摘Jones J W Saunders C Mcleod R 1994IEEE Trans Eng Manage1994,41,1:1
16Northern Hemisphere surface air temperature variations: 1851-- 1984显示文摘Jones P D S C B Raper R S Bradley 1986JClim Appl Meteor1986,25,2:1
17The thermal degradation and EP performance of Zinc dialkydithiophophate additives in white oil显示文摘Coy R C Jones R B 1979ASLE Transaction1979,24,1:1
18Continuity of kinetics between sub-and supercritical regimes in the oxidation of a high-volatile solid substrate显示文摘JONES J C CHIZ P S KOH R MATTHEW J 1996Fuel1996,75,15:1
19Comparative wear under four different tribological conditions of acetylene enhanced cross-linked ultra high molecularweight polyethylene显示文摘Marrs H Barton D C Jones R A 1999J Mater Sci:Mater Med1999,10,:1
20Determination of pesticides in soil samples by supercritical fluid chromatography-atmospheric pressure chemical ionisation mass spectrometric detection显示文摘Dost K Jones D C Auerbach R 2000Analyst2000,125,10:1
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