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51篇 您的检索式:作者名="Inger A"
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1The oral commensal Streptococcus mitis activates the aryl hydrocarbon receptor in human oral epithelial cells显示文摘Streptococcus mitis(S. mitis) is a pioneer commensal bacterial species colonizing many of the surfaces of the oral cavity in healthy individuals. Yet, not much information is available regarding its interaction with the host. We used examination of its transcriptional regulation in oral keratinocytes to elucidate some of its potential roles in the oral cavity. Transcription factor analysis of oral keratinocytes predicted S. mitis-mediated activation of aryl hydrocarbon receptor(Ah R). Activation and functionality of Ah R was confirmed through nuclear translocation determined by immunofluorescence microscopy and real-time polymerase chain reaction with reverse transcription analysis of CYP1A1, the hallmark gene for Ah R activation. Addition of Streptococcus mutans or Streptococcus gordonii did not induce CYP1A1 transcription in the keratinocyte cultures. Introduction of an Ah R-specific inhibitor revealed that S. mitis-mediated transcription of CXCL2 and CXCL8 was regulated by Ah R. Elevated levels of prostaglandin E2(enzyme-linked immunosorbent assay) in supernatants from S. mitis-treated oral epithelial cells were also attenuated by inhibition of Ah R activity. The observed Ah R-regulated activities point to a contribution of S. mitis in the regulation of inflammatory responses and thereby to wound healing in the oral cavity. The concept that the oral commensal microbiota can induce Ah R activation is important, also in view of the role that Ah R has in modulation of T-cell differentiation and as an anti-inflammatory factor in macrophages.stian a engen gro h rørvik olav schreurs inger js blix karl schenck 2017International Journal of Oral Science2017,9,3:2
2Increased plasma endothelin - 1 in acute ischemic stroke显示文摘Ziv Flem inger G D jalaetti R et a| 1992Stroke1992,23,7:1
3Source partitioning using stable isotopes: coping with too muchvariation 显示文摘Parnell A C Inger R Bearhop S 2010PLoS ONE2010,5,3:1
4Source partitioning using stable isotopes: coping with too much variation显示文摘Parnell A C Inger R Bearhop S 2010PLoS One2010,5,3:1
5The CRIT Study: Anemiaand blood transfusion in the critically ijl-current clinical practice inthe United States 显示文摘Corwin HL Get^inger A Pearl RG 2004Critical Care Medicine2004,32,1:1
6Both freshly prepared and frozen-stored amniotic membrane cel s express the complement inhibitor CD59显示文摘Füst A Pál inger E Stündl A 0,,:1
7Methacrylate and epoxy functionalized nano-composites based on silsesquioxane cores for use in dental applications显示文摘Soh MS Yap AUJ Sel inger A 0,,:1
8Source Partitioning Using Stable Isotopes: Coping with Too Much Variation显示文摘Parnell A C Inger R Bearhop S Jackson AL 2010PLoS ONE2010,5,3:1
9The fibroblast-like synovial cel in rheumatoid arthritis:a key player in inflammation and joint destruction显示文摘Mor A Abramson SB Pil inger MH 0,,02:1
10Calibration of NIR to assess lignin composition (H /G ratio) in maritime pine wood using analytical pyrolysis as the reference method显示文摘ALVES A SCHWANN INGER M PEREIRA H 2006Holzforschung2006,60,1:1
11Intimal proliferation and restenosis in paclitaxel-eluting stents with aminoparylene as carrier substance in swines显示文摘Flueckiger A Strahm Y Bil inger M 0,,03:1
12Kirchhoff modeling, inversion for reflectivity, and subsurface illumination显示文摘Duquet B Marfurt J K Dell inger J A 2000Geophysics2000,65,4:1
13Improvement of the preparation procedure of carbon stripper foils from the laser plasma ablation-deposition process显示文摘MAIER-KOMOR P BERGMAIER A DOLL- INGER G 1997Nuclear Instruments and Methods in Physics Research A1997,397,:1
14A human colon cancer cel capable of initiating tumour growth in immunodeficient mice显示文摘O'Brien CA Pol ett A Gal inger S Dick JE 0,,7123:1
15The critical role of kinase activity of interleukin-1 receptor-associated kinase 4 in animal models of joint inflammation显示文摘Koziczak-Holbro M Littlewood-Evans A P?l inger B 0,,06:1
16Creating a manufacturing environment that is in harmony with the market-the 'how' of supply chain management显示文摘Inger R Braithwaite A Christopher M 1995Production Planning and Control1995,6,3:1
17Multidiseiplinary management of lung cancer显示文摘SPIRA A ETI'INGER D S 2004N Engl J Med2004,350,4:1
18Effects of workplace incivility and empowerment on newly-graduated nur- ses organizational commitment显示文摘Smith L M Andrusyszyn M A and Lasch- inger H K S 2010Journal of Nursing Management2010,,18:1
19Source parti- tioning using stable isotopes:Coping with too much variation 显示文摘PARNELL A C INGER R BEARHOP S 2010PLOS ONE2010,5,3:1
20Good outcome of adolescent onset anorexia nervosa after systematic treatment, Intermediate to long-term follow-up of a representative county-sample显示文摘Inger H Anne A Sonja H 2004European Child & Adolescent Psychiatry2004,13,5:1
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