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| 1 | High-fidelity multimode fibre-based endoscopy for deep brain in vivo imaging显示文摘Progress in neuroscience relies on new techniques for investigating the complex dynamics of neuronal networks.An ongoing challenge is to achieve minimally invasive and high-resolution observations of neuronal activity in vivo inside deep brain areas.Recently introduced methods for holographic control of light propagation in complex media enable the use of a hair-thin multimode optical fibre as an ultranarrow imaging tool.Compared to endoscopes based on graded-index lenses or fibre bundles,this new approach offers a footprint reduction exceeding an order of magnitude,combined with a significant enhancement in resolution.We designed a compact and high-speed system for fluorescent imaging at the tip of a fibre,achieving a resolution of 1.18±0.04μm across a 50-μm field of view,yielding 7-kilopixel images at a rate of 3.5 frames/s.Furthermore,we demonstrate in vivo observations of cell bodies and processes of inhibitory neurons within deep layers of the visual cortex and hippocampus of anaesthetised mice.This study paves the way for modern microscopy to be applied deep inside tissues of living animal models while exerting a minimal impact on their structural and functional properties. | Sergey Turtaev Ivo T.Leite Tristan Altwegg-Boussac Janelle M.P.Pakan Nathalie L.Rochefort Tomáš Čižmár | 2018 | Light(Science & Applications)2018，7，1： | 8 |
| 2 | Cerebral processing of auditory stimuli in patients with irritable bowel syndrome显示文摘瞄准:用大脑决定功能的磁性的回声成像(fMRI ) 非内脏的刺激的服的处理是否在急躁的肠症候群(IBS ) 被改变病人与健康题目相比。围绕针的内脏躯体集中机制,并且识别心理因素的可能的影响,我们使用了听觉的刺激刺激在他们的感情的质量不同。方法:在 8 个 IBS 病人和 8 控制, fMRI 大小用不同感情的质量(钟声,讨厌的偷看(2000 Hz ) ,中立的词,和感情的词的愉快的声音) 的 4 听觉的刺激的一个块图案被执行。坡度回响 T2 * 加权的顺序被用于功能的扫描。统计地图用一般线性模型被构造。结果:到感情的听觉的刺激,,相对控制的 IBS 病人在感情的处理区域的一个更大的变化与更强壮的释放反应了反应模式,在控制不同,没在令人烦恼或愉快的声音之间区分。到中立听觉的刺激,由对比,仅仅 IBS 病人与大重要激活反应了。结论:到在感情的处理刺激的区域的听觉的刺激的改变的服的反应模式建议在 IBS 的改变的感觉处理不能为内脏的感觉是特定的,但是可能在感情的敏感和感情方面的反应反映概括变化,可能与经常在 IBS 病人发现的心理 comorbidity 联系了。 | Viola Andresen Alexander Poellinger Chedwa Tsrouya Dominik Bach Albrecht Stroh Annette Foerschler Petra Georgiewa Marco Schmidtmann Ivo R van der Voort Peter Kobelt Claus Zimmer Bertram Wiedenmann Burghard F Klapp Hubert Monnikes | 2006 | World Journal of Gastroenterology2006，12，11： | 8 |
| 3 | Predictability of refraction following immediate sequential bilateral cataract surgery(ISBCS)performed under general anaesthesia显示文摘Background:To evaluate the predictability of refraction following immediate sequential bilateral cataract surgery(ISBCS)performed under general anaesthesia.Methods:This is a retrospective review of all ISBCS performed at Kantonsspital Winterthur,Switzerland,between April 2000 and September 2013.The case notes of 250 patients were reviewed.Patients having full refraction reported(110 patients/220 eyes)were included.210(95%)eyes had a straight forward phacoemulsification with posterior chamber intraocular lens implantation,seven eyes had a planned extracapsular cataract extraction(ECCE);three eyes had an intracapsular cataract extraction.Results:Both eyes of 110 patients(64 women,46 men)with a mean age of 79.0 years,standard deviation(SD)±11.4(range 26 to 97 years)were included.Median preoperative best corrected visual acuity(BCVA)was 0.5 LogMAR in the first eye,the interquartile range(IQR)was[0.4,1.2];0.7 LogMAR in the second eye with IQR[0.4,1.8].At one month,the median BCVA was 0.2 LogMAR,IQR[0.1,0.3]in the first eye,median BCVA was 0.1 LogMAR and IQR[0.0,0.5]in the second eye.There were 3 eyes(3%)that lost 3 lines or more in BCVA at one month(control vs.pre-operatively).In all three cases,poor visual acuity had been recorded pre-operatively(>1 LogMAR).Achieved refraction was within±1.0 D of the target in 83%of eyes.There were only 5%(n=6)of cases where if delayed sequential bilateral extraction had been performed could potentially intraocular lens(IOL)choice have been adjusted,in four of these cases,target refraction was within±1.0 D in the second eye.Conclusions:ISBCS performed under general anaesthesia achieves target refraction in 83%of eyes after consideration of complications,ocular co-morbidities and systemic restrictions.In the majority of cases where IOL power calculation could be considered,the achieved refraction of the second surgical eye was within±1.0 D of intended refraction.This undermines the utility of IOL power adjustments in the second surgical eye. | Ivo Guber Laurent Rémont Ciara Bergin | 2015 | Eye and Vision2015，2，1： | 3 |
| 4 | Triplet formation by charge recombination in thin film Blends of perylene red and pyrene : developing a target model for the photophysics of organic photovoltaic materials显示文摘 | Williams R M Ivo N V A Stokkum H M V | 2013 | Physical Chemistry B2013，117，11： | 1 |
| 5 | Supersonic air flow due to solid-liquid impact 显示文摘 | Glasheen J W Peters Ivo R Gordillo J M | 2010 | Phys Fluids2010，2，： | 1 |
| 6 | Seizures induced by intracerebral injection of thrombin: a model of intracerebral hemorrhage显示文摘 | Kevin R Lee Ivo Drury Elizabeth Vitarbo | | 0，，： | 1 |
| 7 | Using TraSMAPI for the assessment of multi-agent traffic management solutions显示文摘 | Ivo J P M Timoteo Miguel R Araujo Rosaldo J F Rossetti | 2012 | Progress in Artificial Intelligence2012，1，2： | 1 |
| 8 | Use of modified acti- vated carbon for the oxidation of aqueous sulfide显示文摘 | Bruno R S Lemos Ivo F Teixeira | 2012 | Car- bon2012，50，： | 1 |
| 9 | Review of IPO Activity, Pri- cing and Allocations 显示文摘 | RITTER JAY R IVO W | 2002 | Journal of Finance2002，，57： | 1 |
| 10 | Biochips at work: Porous silicon microbiosensor for proteomic diagnostic 显示文摘 | Luca D S Ivo R Andrea Mario Rossi | 2007 | Journal of Physics : Condensed Matter2007，19，39： | 1 |
| 11 | No association between dopamine D4 receptor gene variants and Novelty Seeking显示文摘 | J(o)nsson EG Ivo R Gustavsson JP | 2002 | Molecular Psychiatry2002，7，1： | 1 |
| 12 | Sample Digestion Procedures for Trace Element Determination显示文摘 | Ivo Novozamsky Hans J van der Lee Victor J R Houba | | 0，，3： | 1 |
| 13 | Porous silicon-based optical microsensor for the detection of L-glutamine显示文摘 | Luca D S Lucia R Ivo R | 2006 | Biosensors and Bioelectronics2006，21，8： | 1 |
| 14 | Surgical resection in the treatment of primary gastrointestinal Non - Hodgkin Is lymphoma: retrospective study 显示文摘 | Ivo R Jasminka KM Igor A | 2002 | Croat Med J2002，43，5： | 1 |
| 15 | UV vis,IR spectra and thermal studies of charge transfer complexformed between poly (amidoamine) dendrimers and iodine 显示文摘 | Moamen S R Akram M E D Ivo G | 2007 | Spectrochimica Acta Part A2007，67，： | 1 |
| 16 | The NOTCH4 Locus and schizophrenia: analyses in German and Palestinian Arab population 显示文摘 | Cichn S Schumacher J Ivo R | 2001 | Am J Med Genet2001，105，： | 1 |
| 17 | Tuberculous spondylitis and para- vertebral abscess formation after kyphoplasty: a case report显示文摘 | Ivo R Sobottke R Seiert H | 2010 | Spine2010，35，： | 1 |
| 18 | Adsorption onto fluidized powdered activated carbon flocs-PACF显示文摘 | ANA L IVO A S JORGE R | | 0，，03： | 1 |
| 19 | Accurate vapourliquid equilibrium calculations for complex systems using the reaction Gibbs ensemble Monte Carlo simulation method 显示文摘 | Martin Lisal Wilham R Smith Ivo Nezbeda | | Fluid Phase EquilibriaVolume0，，12： | 1 |
| 20 | Evaluation of the impact of ehiropodist eare in the secondary prevention of foot ulcerations in diabetic subjects显示文摘 | Johannes P Wahraud H Ivo R M | 1999 | Diabetes Care1999，22，10： | 1 |
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