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| 1 | 大洋钻探对洋底以下生命的探索显示文摘对ODP采集的沉积物样品的地球化学研究揭示,在全世界所有的大洋底以下都发现了细菌活动,洋底沉积物中的生物圈可能构成了地球生物数量的1/3,该生物圈通过调节海洋沉积物的成岩作用和大洋玄武岩的风化,影响到长期的全球生物地球化学循环。DSDP最早提出了海洋沉积物中细菌活动性的证据,ODP的一系列航次提供了各种不同环境下深部生物圈细菌群落以及细菌参与的地球化学过程纪录。ODP201是第一个专门致力于研究洋底以下生命的大洋钻探航次,它记录了从富有机质的边缘沉积到贫有机质的开阔海沉积环境的洋底以下细菌活动性和细菌群落的连续性,201航次还揭示,古海洋环境对现在正活跃于深海沉积物中的原核生物群落造成了影响。 | Steven D'Hondt 朱毅杰 | 2003 | 地球科学进展2003，18，5： | 6 |
| 2 | Reversed-phase fused-core HPLC modeling of peptides显示文摘Different fused-core stationary phase chemistries(C18,Amide,Phenyl-hexyl and Peptide ES-C18) were used for the analysis of 21 structurally representative model peptides.In addition,the effects of the mobile phase composition(ACN or MeOH as organic modifier;formic acid or acetic acid,as acidifying component) on the column selectivity,peak shape and overall chromatographic performance were evaluated.The RP-amide column,combined with a formic acid-acetonitrile based gradient system,performed as best.A peptide reversed-phase retention model is proposed,consisting of 5 variables:log SumAA,log Sv,clog P,log nHDon and log nHAcc.Quantitative structure-retention relationship(QSRR) models were constructed for 16 different chromatographic systems.The accuracy of this peptide retention model was demonstrated by the comparison between predicted and experimentally obtained retention times,explaining on average 86% of the variability.Moreover,using an external set of 5 validation peptides,the predictive power of the model was also demonstrated.This peptide retention model includes the novel in-silico calculated amino acid descriptor,AA,which was calculated from log P,3D-MoRSE,RDF and WHIM descriptors. | Matthias D'Hondt Bert Gevaert Sofie Stalmans Sylvia Van Dorpe Evelien Wynendaele Kathelijne Peremans Christian Burvenich Bart De Spiegeleer | 2013 | Journal of Pharmaceutical Analysis2013，3，2： | 3 |
| 3 | Treatment of small-bowel fistulae in the open abdomen with topical negative-pressure therapy显示文摘 | Mathieu D’Hondt Dirk Devriendt Frank Van Rooy Franky Vansteenkiste André D’Hoore Freddy Penninckx Marc Miserez | 2011 | The American Journal of Surgery2011，，： | 2 |
| 4 | Analytical quality-by-design approach for sample treatment of BSA-containing solutions显示文摘The sample preparation of samples conlaining bovine serum albumin(BSA),e.g..as used in transdermal Franz diffusion cell(FDC) solutions,was evaluated using an analytical qualily-by-design(QbD)approach.Traditional precipitation of BSA by adding an equal volume of organic solvent,often successfully used with conventional HPLC-PDA,was found insufficiently robust when novel fused-core HPLC and/or UPLC-MS methods were used.In this study,three factors(acetonitrile(%).formic acid(%) and boiling time(min)) were included in the experimental design to determine an optimal and more suitable sample treatment of BSAcontaining FDC solutions.Using a QbD and Derringer desirability(D) approach,combining BSA loss,dilution factor and variability,we constructed an optimal working space with the edge of failure defined as D<0.9.The design space is modelled and is confirmed to have an ACN range of 83 ± 3% and FA content of 1 ±0.25%. | Lien Taevernier Evelien Wynendaele Matthias D'Hondt Bart De Spiegeleer | 2015 | Journal of Pharmaceutical Analysis2015，5，1： | 2 |
| 5 | Ring chromosome 15 syndrome显示文摘 | Fryns JP Timmermans J Hondt FD | 1979 | Hum Genet1979，51，： | 1 |
| 6 | Indications, safety, and feasibility of conversion of failed bariatric surgery to Roux- en-Y gastric bypass: A retrospective comparative study with primary laparoscopic Roux-en-Y gastric bypass 显示文摘 | Deylgat B D'Hondt M Pottel H | 2012 | Surg Endosc2012，26，： | 1 |
| 7 | First-line systemic treat- ment of ovarian cancer:a critical review of available evidence and expectations for future directions显示文摘 | Metzger-Filho O Moulin C D'Hondt V | 2010 | Curr Opin Oncol2010，22，5： | 1 |
| 8 | Relation of ultrasonic tissue characterization with integrated backscatter to contractile reserve in chronic left ventricular ischemic dysfunction显示文摘 | D′Hondt A M Melin J A | 1998 | Am J Cardiol1998，81，1： | 1 |
| 9 | Minimally invasive liver resection for huge(≥10cm)tumors:an international multicenter matched cohort study with regression discontinuity analyses显示文摘Background:The application and feasibility of minimally invasive liver resection(MILR)for huge liver tumours(≥10 cm)has not been well documented.Methods:Retrospective analysis of data on 6,617 patients who had MILR for liver tumours were gathered from 21 international centers between 2009-2019.Huge tumors and large tumors were defined as tumors with a size≥10.0 cm and 3.0-9.9 cm based on histology,respectively.1:1 coarsened exact-matching(CEM)and 1:2 Mahalanobis distance-matching(MDM)was performed according to clinically-selected variables.Regression discontinuity analyses were performed as an additional line of sensitivity analysis to estimate local treatment effects at the 10-cm tumor size cutoff.Results:Of 2,890 patients with tumours≥3 cm,there were 205 huge tumors.After 1:1 CEM,174 huge tumors were matched to 174 large tumors;and after 1:2 MDM,190 huge tumours were matched to 380 large tumours.There was significantly and consistently increased intraoperative blood loss,frequency in the application of Pringle maneuver,major morbidity and postoperative stay in the huge tumour group compared to the large tumour group after both 1:1 CEM and 1:2 MDM.These findings were reinforced in RD analyses.Intraoperative blood transfusion rate and open conversion rate were significantly higher in the huge tumor group after only 1:2 MDM but not 1:1 CEM.Conclusions:MILR for huge tumours can be safely performed in expert centers It is an operation with substantial complexity and high technical requirement,with worse perioperative outcomes compared to MILR for large tumors,therefore judicious patient selection is pivotal. | Tan-To Cheung Xiaoying Wang Mikhail Efanov Rong Liu David Fuks Gi-Hong Choi Nicholas LSyn Charing CChong Iswanto Sucandy Adrian KHChiow Marco VMarino Mikel Gastaca Jae Hoon Lee TPeter Kingham Mathieu D’Hondt Sung Hoon Choi Robert PSutcliffe Ho-Seong Han Chung Ngai Tang Johann Pratschke Roberto ITroisi Brian KPGoh International Robotic and Laparoscopic Liver Resection Study Group Collaborators | 2021 | Hepatobiliary Surgery and Nutrition2021，10，5： | 1 |
| 10 | Relating proper- ties and functions from patents to TRIZ trends显示文摘 | Verhaegen P -A D' hondt J Veltommen J | 2009 | C1RP Journal of Manufacturing Science and Technology2009，1，3： | 1 |
| 11 | Usefulness of tissue Doppler imaging to evaluate pulmonary capillary wedge pressure during exercise in patients with reduced left ventricular eiection fraction显示文摘 | Marehandise S Vanoverschelde JL D'Hondt AM | 2014 | Am J Cardiol2014，113，12： | 1 |
| 12 | Childhood obesity affects fine motor skill performance under different postural constraints 显示文摘 | D'HONDT E BENEDICTE D I1SE DB | 2008 | Neurosci Letters2008，440，1： | 1 |
| 13 | Using Genetic Programming to Generate Protocol Adaptors for Interprocess Communication 显示文摘 | Wemer Van Belle Tom Mens Theo D'Hondt | 2003 | Lecture Notes in Computer Science2003，2606，： | 1 |
| 14 | Late Cretaceous precessional cycles in double time:a warm-earth Milankovitch response显示文摘 | Park J D' Hondt S L King J W | 1993 | Science1993，261，5127： | 1 |
| 15 | Fine and gross motor skills differ between healthy-weight and obese children 显示文摘 | GENTIER I D'HONDT E SHULTZ S | 2013 | Res Dev Disabi12013，34，11： | 1 |
| 16 | Flow in the engine com-partment:analysis and optimization显示文摘 | D’Hondt M Gilliéron P Devinant P | 2011 | International Journal ofAerodynamics2011，134，： | 1 |
| 17 | Novel treatment strategies for soft tissue sarcoma 显示文摘 | Kaspcr B Gil T D' Hondt H | 2007 | Critical Reviews in Oncology/Hematology2007，62，： | 1 |
| 18 | Catalytic glycerol conversion into 1,2-propanediol in absence of added hydrogen 显示文摘 | D'Hondt E Van de Vyver S Sels B F | 2008 | Chemical Communications2008，，45： | 1 |
| 19 | An effect of dissolved nutrient concentrations on alkenone based temperature estimates显示文摘 | Epstein B L Hondt S D Quinn J G | 1998 | Paleoceanography1998，13，2： | 1 |
| 20 | Comparison of myocardial contrast echocardiography with NC100100 and(99m)Tc sestamibi SPECT for detection of resting myocardial perfusion abnormalities in patients with previous myocardial infarction显示文摘 | Jucquois I Nihoyannopoulos P D'Hondt AM | | 0，，05： | 1 |
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