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74篇 您的检索式：作者名="Holde M"

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	题名	作者	年代	出处	被引量
1	Cellular and molecular aspects of gastric cancer显示文摘胃的癌症与变的负担仍然是一个全球杀手从发展了到发展中的世界。癌症沿着被定义由的一个多级式的过程发展不同组织学并且 pathophysiological 阶段。几基因、渐成说的改变调停从一个的转变上演到另外一个,这些在 oncogenes 包括变化,瘤压制或基因和房间骑车并且错配修理基因。在对胃的癌症的战斗的最重要的进展为这癌症作为最重要的获得的病因论的代理人与 Helicobacter pylori (H pylori ) 的角色的识别来了。最近的工作在阐明上集中了位于肿瘤的过程下面的复杂 host/microbial 相互作用。现在进这癌症的致病和阻止并且根除的前景有可观的卓见疾病成为了现实。也许更重要地, H 导致 pylori 的胃的致癌作用的学习为理解更复杂的人的癌症提供一个范例。在这评论,我们检验位于 H 下面的分子、细胞的事件导致 pylori 的胃的癌症。	Malcolm G Smith Georgina L Hold Eiichi Tahara Emad M El-Omar	2006	World Journal of Gastroenterology2006，12，19：	29
2	Role of the gut microbiota in inflammatory bowel disease pathogenesis: What have we learnt in the past 10 years?显示文摘Our understanding of the microbial involvement in inflammatory bowel disease(IBD) pathogenesis has increased exponentially over the past decade. The development of newer molecular tools for the global assessment of the gut microbiome and the identification of nucleotide-binding oligomerization domain-containing protein 2 in 2001 and other susceptibility genes for Crohn's disease in particular has led to better understanding of the aetiopathogenesis of IBD. The microbial studies have elaborated the normal composition of the gut microbiome and its perturbations in the setting of IBD. This altered microbiome or 'dysbiosis' is a key player in the protracted course of inflammation in IBD. Numerous genome-wide association studies have identified further genes involved in gastrointestinal innate immunity(including polymorphisms in genes involved in autophagy: ATG16L1 and IGRM), which have helped elucidate the relationship of the local innate immunity with the adjacent luminal bacteria. These developments have also spurred the search for specific pathogens which may have a role in the metamorphosis of the gut microbiome from a symbiotic entity to a putative pathogenic one. Here we review advances in our understanding of microbial involvement in IBD pathogenesis over the past 10 years and offer insight into how this will shape our therapeutic management of the disease in the coming years.	Georgina L Hold Megan Smith Charlie Grange Euan Robert Watt Emad M El-Omar Indrani Mukhopadhya	2014	World Journal of Gastroenterology2014，20，5：	21
3	Distal popliteal and tibioperoneal transluminal angioplasty: long-term follow-up 显示文摘	Bull P G Mendel H Hold M	1992	J Vasc Interv Radiol1992，3，1：	1
4	The Sanfte Mobilitaet project,achieving reduced car-dependence In European resort areas显示文摘	Holding D M	2001	Tourism Management2001，22，：	1
5	Fermentation studies on Lucerne显示文摘	Carpintero M C Holding A J Donald P M	1969	J Sci Fdagric1969，20，12：	1
6	Diagnosis of beta-thalassaemia by DNA amplification in single blastomeres from mouse preimplantation embryos 显示文摘	Holding C Monk M	1989	Lancet1989，2，8662：	1
7	Fermentation studies on Lucerne显示文摘	Carpintero M C Holding A J McDonald P	1969	J Sci Food Agric1969，20，：	1
8	Detection of human novel developmental genes in cDNA derived on replicate individual preimplantation embryos 显示文摘	Holding C Bolton V Monk M	2000	Mol Hum Reprod2000，6，9：	1
9	Detection of human novel developmental genes in cDNA derived om replicate individual preimplantation embryos显示文摘	Holding C Bolton V Monk M	2000	Mol Hum Reprod2000，6，9：	1
10	Use of autologous platelet concentrate in blepharoplasty surgery显示文摘	VICK V L HOLDS J B HARTSTEIN M E	2006	Ophthal Plast Reconstr Surg2006，22，2：	1
11	Human embryonic genes re-expressed in cancer cells 显示文摘	Monk M Holding C	2001	Oncogene2001，20，56：	1
12	Genetic aspects of inflammation and cancer 显示文摘	Hold G L E1-Omar M E	2008	Biochem J2008，410，2：	1
13	Human embryonic genes reexpressed in cancer cells 显示文摘	Monk M Holding C	2001	Oncogene2001，20，：	1
14	Detection of human novel developmental genes in cDNA derived from replicate individual preimplantation embryos显示文摘	Holding C Bolton V Monk M	2000	Mol Hum Reprod2000，6，9：	1
15	Spatial model and interpolation of monthly temperature using kriging 显示文摘	HOLD AWAY M R	1996	Climate Resources1996，6，3：	1
16	The maize flouryl gene encodes a novel endoplasmic reticulum protein involved in zein protein body formation 显示文摘	HOLDING D R OTEGUI M S LI B	2007	Plant Cell2007，19，8：	1
17	Molecular engineering of peripherally and axially modified phthalocyanines for optical limiting and nonlinear optics 显示文摘	O′FLAHERTY M S HOLD S V HANACK M	2003	Adv Mater2003，15，1：	1
18	Human embryonic genes re-expression in cancer cells显示文摘	Monk M Holding C	2001	Oncogene2001，20，56：	1
19	The metabolism and excretion of curcumin ( 1,7-bis-( 4-hydroxy-3-methoxyphenyl ) -1,6-haptadiene- 3,5-dione) in the rat 显示文摘	Hold G M Plummer J L Ryan A J	1978	Xenobiotica1978，8，12：	1
20	Use of a variance estimator for interferometer angle accuracy显示文摘	Greenspan M Hold H D Radza B P	1988	IEEE1988，2572，6：	1

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