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| 1 | Phase angle obtained by bioelectrical impedance analysis independently predicts mortality in patients with cirrhosis显示文摘AIM To evaluate the prognostic value of the phase angle(PA)obtained from bioelectrical impedance analysis(BIA) for mortality prediction in patients with cirrhosis. METHODS In total, 134 male cirrhotic patients prospectively completed clinical evaluations and nutritional assessment by BIA to obtain PAs during a 36-mo follow-up period. Mortality risk was analyzed by applying the PA cutoff point recently proposed as a malnutrition marker(PA ≤ 4.9°) in Kaplan-Meier curves and multivariate Cox regression models. RESULTS The patients were divided into two groups according to the PA cutoff value(PA > 4.9°, n = 73; PA ≤ 4.9°, n = 61). Weight, height, and body mass index were similar in both groups, but patients with PAs > 4.9° were younger and had higher mid-arm muscle circumference, albumin, and handgrip-strength values and lower severe ascites and encephalopathy incidences, interleukin(IL)-6/IL-10 ratios and C-reactive protein levels than did patients with PAs ≤ 4.9°(P ≤ 0.05). Forty-eight(35.80%) patients died due to cirrhosis, with a median of 18 mo(interquartile range, 3.3-25.6 mo) follow-up until death. Thirty-one(64.60%) of these patients were from the PA ≤ 4.9° group. PA ≤ 4.9° significantly and independently affected the mortality model adjusted for Model for End-Stage Liver Disease score and age(hazard ratio = 2.05, 95%CI: 1.11-3.77, P = 0.021). In addition, Kaplan-Meier curves showed that patients with PAs ≤ 4.9° were significantly more likely to die. CONCLUSION In male patients with cirrhosis, the PA ≤ 4.9° cutoff was associated independently with mortality and identified patients with worse metabolic, nutritional, and disease progression profiles. The PA may be a useful and reliable bedside tool to evaluate prognosis in cirrhosis. | Giliane Belarmino Maria Cristina Gonzalez Raquel S Torrinhas Priscila Sala Wellington Andraus Luiz Augusto Carneiro D'Albuquerque Rosa Maria R Pereira Valéria F Caparbo Graziela R Ravacci Lucas Damiani Steven B Heymsfield Dan L Waitzberg | 2017 | World Journal of Hepatology2017，9，7： | 11 |
| 2 | Accurate measurement of liver, kidney, and spleen volume and mass by computerized axial tomography显示文摘 | Heymsfield SB Fulenwider T Nordlinger B | 1979 | Ann Intern Med1979，90，2： | 1 |
| 3 | Human-body Composition and the Epidemiology of Chronic Disease显示文摘 | BAUMGARTNER R N HEYMSFIELD S B ROCHE A F | 1995 | Obes Res1995，3，： | 1 |
| 4 | Dual en- ergy X-Ray absorptiometry body composition reference values from NHANES 显示文摘 | KELLY T L WILSON K E HEYMSFIELD S B | 2009 | PLoS ONE2009，4，9： | 1 |
| 5 | Human-body Composition and the Epidemiology of Chronic Disease显示文摘 | Baumgartner R N Heymsfield S B Roche A F | 1995 | Obes Res1995，，3： | 1 |
| 6 | Accurate measurement of liver, kidney, and spleen volume and mass by computerized axial tomography 显示文摘 | Heymsfield SB Fulenwider T Nordlinger B | 1979 | Ann Intern Med1979，，： | 1 |
| 7 | Short sleep duration as a risk factor for hypertension: analyses of the first National Health and Nutrition Examination Survey 显示文摘 | Gangwisch JE Heymsfield SB Boden-Albala B | 2006 | Hypertension2006，47，5： | 1 |
| 8 | Short sleep duration as a risk factor for hypertension: analyses of the First National Health and Nutrition Examination Survey显示文摘 | Gangwisch JE Heymsfield SB Boden-Albala B | 2006 | Hypertension2006，47，： | 1 |
| 9 | Abdominal composition quantified by computed tomography 显示文摘 | Baumgartner R N Heymsfield S B Roche A F | 1988 | Am J Clin Nutr1988，48，： | 1 |
| 10 | Aeettrate measurement of liver,kidney and spleen volume and mass by computerized axial tomegraphy显示文摘 | Heymsfield SB Fulenwider T Nordlinger B | 1979 | Ann Intern Med1979，90，2： | 1 |
| 11 | Short sleep duration as a risk factor for hypertension:analyses of the first National Health and Nutrition Examination Survey 显示文摘 | Gangwisch JE Heymsfield SB Boden-Albala B | 2006 | Hypert2006，47，5： | 1 |
| 12 | Weight management using a meal replacement strategy: meta and pooling analysis from six studies 显示文摘 | HEYMSFIELD S B van MIERLO C A van der KNAAP H C | 2003 | Int J Obes Relat Metab Disord2003，27，5： | 1 |
| 13 | Accurate measurement of liver, kidney and spleen volume and mass by computerized axial tomography 显示文摘 | Heymsfield SB Fuleonwider T Nordlinger B | 1979 | Ann Intern Med1979，90，2： | 1 |
| 14 | Accurate measurement of liver, kideny, spleen volume and mass by computed axial tomography显示文摘 | Heymsfield SB Fulerwider T Nordinger B | 1979 | Ann Intern Med1979，90，2： | 1 |
| 15 | Warm core structure of Hurricane Erin Diagnosed from high altitude dropsondes during CAMEX-4显示文摘 | I HALVERSON J B SIMPSON J HEYMSFIELD G | 2006 | J Atmos Sci2006，63，1： | 1 |
| 16 | Short sleep duration as a risk factor for hypertension显示文摘 | Heymsfield SB Boden-Albala B | 2006 | Hypertension2006，47，5： | 1 |
| 17 | Accurate measurement of liver,kinding and spleen volume and mass by computerited axial tomography显示文摘 | Heymsfield S Fulonnicler T Nerdingler B | 1979 | Ann Intern Med1979，90，2： | 1 |
| 18 | Menopausal Changes in Body Composition and Energy Expenditure显示文摘 | HEYMSFIELD S B GALLAGHER D POEHLMAN E T | 1994 | Exp Gerontol1994，29，： | 1 |
| 19 | Short sleep duration as a risk factor for hypertension: analyses of the first national health and nutrition examination survey 显示文摘 | Gangwisoh JE Heymsfield SB Boden-Albala B | 2006 | Hypertension2006，47，： | 1 |
| 20 | Effect of calcium sup plementation oft weight and fat loss in women 显示文摘 | Shapses S A Heshka S Heymsfield S B | 2004 | J Clin Endocrinol Metab2004，89，2： | 1 |
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