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| 1 | 3D reconstruction method and connectivity rules of fracture networks generated under different mining layouts显示文摘In current research,a series of triaxial tests,which were employed to simulate three typical mining layouts(i.e.,top-coal caving,non-pillar mining and protected coal seam mining),were conducted on coal by using MTS815 Flex Test GT rock mechanics test system,and the fracture networks in the broken coal samples were qualitatively and quantitatively investigated by employing CT scanning and 3D reconstruction techniques.This work aimed at providing a detail description on the micro-structure and fractureconnectivity characteristics of rupture coal samples under different mining layouts.The results show that:(i)for protected coal seam mining layout,the coal specimens failure is in a compression-shear manner and oppositely,(ii)the tension-shear failure phenomenon is observed for top-coal caving and non-pillar mining layouts.By investigating the connectivity features of the generated fractures in the direction ofσ_1,under different mining layouts,it is found that the connectivity level of the fractures of the samples corresponding to non-pillar mining layout was the highest. | Zhang Ru Ai Ting Li Hegui Zhang Zetian Liu Jianfeng | 2013 | International Journal of Mining Science and Technology2013，23，6： | 18 |
| 2 | PIK3CA mutation asso- ciates with improved outcome in breast cancer 显示文摘 | Kalinsky K Jacks LM Heguy A | 2009 | Clin Cancer Res2009，15，16： | 1 |
| 3 | The chicken Il-I receptor:differential evolution of the cytoplasmic and extracellular domains显示文摘 | GUIDA S HEGUY A MELLI M | 1992 | Gene1992，111，： | 1 |
| 4 | PIK3CA mutation associates with improved outcome in breast cancer 显示文摘 | Kalinsky K Jacks LM Heguy A | 2009 | Clin Cancer Res2009，15，16： | 1 |
| 5 | Modification of gene expression of the small airway epithelium in response to cigarette smoking显示文摘 | Harvey BG Heguy A Leopold PL | 2007 | J Mol Med (Bed)2007，85，1： | 1 |
| 6 | Variability of antioxi- dant-related gene expression in the airway epithelium of cigarette smokers显示文摘 | Hackett NR Heguy A Harvey BG | 2003 | Am J Respir Cell Mol Biol2003，29，31： | 1 |
| 7 | PIK3CA mutation associates with improved outcome in breast cance显示文摘 | Kalinsky K Jacks LM Heguy A | | 0，，16： | 1 |
| 8 | Up-regulation of expression of the ubiquitin carboxyl-terminal hydrolase L1 gene in human airway epithelium of cigarette smokers显示文摘 | Carolan B J Heguy A Harvey B G | 2006 | Cancer Res2006，66，10： | 1 |
| 9 | Up-regulation of ex- pression of the ubiquitin carboxyl-terminal hydrolase L1 gene in human airway epithelium of cigarette smokers 显示文摘 | Carolan B J Heguy A Harvey BG | 2006 | Cancer Res2006，66，10： | 1 |
| 10 | Modification of gene expression of the small airway epithelium in response to cigarette smoking显示文摘 | Harvey B G Heguy A Leopold P L | | 0，，01： | 1 |
| 11 | Down-regulation of the Notch Pathway in Human Airway Epithelium in Associa- tion with Smoking and Chronic Obstructive Pulmonary Dis- ease显示文摘 | Tilley AE Harvey BG Heguy A | 2009 | Am J Respir Crit Care Med2009，179，6： | 1 |
| 12 | Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease显示文摘 | Tilley AE Harvey BG Heguy A | 2009 | Am J Respir Crit Care Med2009，179，6： | 1 |
| 13 | Institutional financial system and Studies of International arrangements of foreign rural implication for China 显示文摘 | Li Hegui | 2009 | Finance2009，，1： | 1 |
| 14 | Down regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease显示文摘 | Tilley AE Harvey BG Heguy A | | 0，，06： | 1 |
| 15 | PIK3CA mutation associates with improved outeorne in breast cancer 显示文摘 | Kalinsky K Jacks L M Heguy A | 2009 | Clin Cancer Res2009，15，16： | 1 |
| 16 | PIK3CA mutation associates with improved outcome in breast cancer 显示文摘 | Kalinsky K Jacks L M Heguy A | 2009 | Clin Cancer Res2009，15，16： | 1 |
| 17 | Important part of bell-less blast furnace charging--platform formation 显示文摘 | Du Hegui and Guo Kezhong | 1995 | Iron- making1995，6，3： | 1 |
| 18 | Arrhythmogenic properties of dismantling cadherin-mediated adhesion in murine hearts显示文摘Objective:To evaluate the arrhythmogenic effects of dismantling cadherin-mediated adhesion by recombinant mouse aminopeptidase N(rmAPN)in murine hearts.Methods:rmAPN was incubated with cultured neonatal rat cardiomyocytes as well as being infused in adult mice.The cell-cell connections were immunolabelled and ob- served by laser confocal microscopy.Disruption of the N-terminal of N-cadherin(N-cad)was detected by western blot and quantitative immunofluorescence.The risk of inducible ventricular tachyarrhythmia was evaluated in mice by an electrophysiological study.Results:Disrupted cell-cell contact was observed in cultured neonatal rat cardiomyocytes in response to 30-40 ng/μL rmAPN.Loss of the N-terminal in N-cad and altered distribution of connexin 43(Cx43)were observed in hearts from rmAPN-infused mice.In addition,a reduction of phosphorylated Cx43 was also detected concomitant with redistribution of Cx43.Electrophysiological studies of rmAPN-infused mice showed prolonged QRS duration and increased inducibility of ventricular tachycardias.Conclusion: Disruption of N-cad by rmAPN contributes to gap junction remodeling and may elicit arrhythmogenic effects.The disorder of adherent junctions by proteolytic enzymes may play an important role in arrhythmogenic mechanisms in correlated diseases. | Hongjun Zhu Hegui Wang Xiwen Zhang Xiaofeng Hou Kejiang Cao Jiangang Zou | 2010 | The Journal of Biomedical Research2010，24，4： | 1 |
| 19 | OXIDATION OF Ti IN MOLTEN Cu UNDER WATERY ATMOSPHERE显示文摘An experimental study has been made of oxidation kinetics of Ti in molten Cu-Ti alloy underwatery atmosphere at 1500℃.The results may be expressed as follows:[Ti]Cu=0.92-0.69t O≤t≤1.0(h)[Ti]Cu=0.02t2-0.14t+0.35 1.0≤t≤6.0(h)where t is time in hour.The apparent rate and order of reaction are:(-d[Ti]Cu)/dt=0.69,pseudo-zeroth order,k=0.69(-d[Ti]Cu)/dt=0.14-0.04t,pseudo-0.85 order,k=0.39The apparent mass tranfer coefficient is k’=0.16 cm/h,and the relation of W2 vs time is:W2=1.04·10-4 | XUE Xiangxin DU Hegui Northeast University of Technology,Shenyang,China XUE Xiangxin Lecturer,Dept.of Ferrous Metallurgy,Northeast University of Technology,Shenyang,110006,China | 1990 | Acta Metallurgica Sinica(English Letters)1990，3，10： | 1 |
| 20 | Intntpleural administration of a serotype 5 adeno-associated virus coding for alphal-antitrypsin mediates persistent, high lung and serum levels of alphal-antitrypsin显示文摘 | De B Heguy A Leopold PL | 2004 | Mol Ther2004，10，6： | 1 |
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