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| 1 | Thymosin alpha 1:A comprehensive review of the literature显示文摘Thymosin alpha 1 is a peptide naturally occurring in the thymus that has long been recognized for modifying,enhancing,and restoring immune function.Thymosin alpha 1 has been utilized in the treatment of immunocompromised states and malignancies,as an enhancer of vaccine response,and as a means of curbing morbidity and mortality in sepsis and numerous infections.Studies have postulated that thymosin alpha 1 could help improve the outcome in severely ill corona virus disease 2019 patients by repairing damage caused by overactivation of lymphocytic immunity and how thymosin alpha 1 could prevent the excessive activation of T cells.In this review,we discuss key literature on the background knowledge and current clinical uses of thymosin alpha 1.Considering the known biochemical properties including antibacterial and antiviral properties,timehonored applications,and the new promising findings regarding the use of thymosin,we believe that thymosin alpha 1 deserves further investigation into its antiviral properties and possible repurposing as a treatment against severe acute respiratory syndrome coronavirus-2. | Asimina Dominari Donald Hathaway III Krunal Pandav Wanessa Matos Sharmi Biswas Gowry Reddy Sindhu Thevuthasan Muhammad Adnan Khan Anoopa Mathew Sarabjot Singh Makkar Madiha Zaidi Michael Maher Mourad Fahem Renato Beas Valeria Castaneda Trissa Paul John Halpern Diana Baralt | 2020 | World Journal of Virology2020，9，5： | 11 |
| 2 | 发达国家纵向整合临床实习模式的发展及其对我国医学教育的启示显示文摘临床实习是医学生将理论知识转化为临床能力和深入临床环境学习的重要途径。纵向整合临床实习模式目前是一种创新性的临床教学方法和理念,它将连续性作为教学原则,很好地解决了原有临床实习中缺乏医疗连续性、课程连续性和教学指导连续性的问题,越来越多的医学院应用此种模式进行临床教学改革。本文对该实习模式的核心内涵、意义和哈佛剑桥模式及其发展与衍变进行阐述,并结合中国医学教育的实际需求进行分析,认为纵向整合临床实习模式可以提高我国临床医生培养质量,促进基层医疗人才队伍建设,增强住院医师规范化培训效果,有助于我国医学教育改革发展。 | 李鸿鹤 David A Hirsh Tara A Singh Yamini Saravanan Rachel Hathaway Bianca Shagrin Elizabeth Gaufberg Arundhati Ghosh 刘君 李扬龄 闻德亮 | 2020 | 中华医学教育杂志2020，40，9： | 10 |
| 3 | Relational dual of the c-means algorithms 显示文摘 | Hathaway R J Davenport J W Bezdek J C | 1989 | Pattern Recognition1989，22，2： | 2 |
| 4 | Molecular characterization of pig muscle phosphoglucose isomerase 显示文摘 | Gww D M Hathaway G M Palmieri R H | 1980 | J Mol Biol1980，142，1： | 1 |
| 5 | Prognostic significance of the initial electrocardiogram in patients with acute myocardial infarction显示文摘 | Hathaway WR Peterson ED Wargner GS | 1998 | J Am Med Assoc1998，279，： | 1 |
| 6 | Convergence and theory for fuzzy C - means clustering: Counterexamples and repairs 显示文摘 | Bezdek J C Hathaway R | 1987 | IEEE Trans Pattern Analysis and Machine Intelligence1987，17，5： | 1 |
| 7 | Deceased absolute counts of T lymphocy to subsects and their relation to disease in squamous cell carcinoma of the head and neck显示文摘 | Kuss I Hathaway B Ferris RL | 2004 | Clin Cancer Res2004，10，11： | 1 |
| 8 | Intra-event variability of Escherichia coli and total suspended solids in ur- ban stormwater runoff显示文摘 | McCarthy D T Hathaway J M Hunt W F | 2012 | Water Research2012，46，20： | 1 |
| 9 | Clustering incomplete relational data using the non-Euclidean relational fuzzy c-means algorithm显示文摘 | Hathaway R J Bezdek J C | 2002 | Pattern Recognition Letters2002，23，13： | 1 |
| 10 | Optimality tests for fixed points of the fuzzy C-means algorithm 显示文摘 | BEZDEK J C HATHAWAY R | 1988 | Pattern Reeognition1988，21，6： | 1 |
| 11 | Torsional strength of pin con- figurations used to fix supracondylar fractures of the humerus in chil- dren 显示文摘 | Zionts LE MeKellop HA Hathaway R | 1994 | J Bone Joint Surg Am1994，2，： | 1 |
| 12 | Decreased absolute counts of T lymphocyte subsets and their relation to disease in squamous cell carcinoma of the head and neck 显示文摘 | Kuss I Hathaway B Ferris RL | 2004 | Clin Cancer Res2004，10，11： | 1 |
| 13 | Low TGFI31 expres- sion prevents and high expression exacerbates diabetic nephropathy inmice显示文摘 | Hathaway C K Gasim A M Grant R | 2015 | ProcNatlAcadSciUSA2015，112，18： | 1 |
| 14 | Thrombosis and heamostosis显示文摘 | | 1986 | ITCH1986，55，： | 1 |
| 15 | Distribution of Fos-like immunoreactivity in the caudal brainstem of the rat following noxious chemical stimulation of the temporomandibular joint 显示文摘 | Hathaway CB Hu JW Bereiter DA | 1995 | J Comp Neurol1995，356，3： | 1 |
| 16 | Convergence theory for fuzzy C-means, Counterexample and repairs 显示文摘 | Bezdek J C Hathaway R Sabiu M W | 1987 | IEEE Transactions On SMC1987，17，5： | 1 |
| 17 | The infrared spectra of some transition-metal perchlorates 显示文摘 | Hathaway B J Underhill A E | 1961 | J Chem Soc1961，65，8： | 1 |
| 18 | Inhibition of casein kinase II by heparin显示文摘 | Hathaway GM Lubben TH Traugh JA | 1980 | Biol Chem1980，255，17： | 1 |
| 19 | Convergence theory for fuzzy C-means:counter-examples and repairs显示文摘 | BEZEDEK J C HATHAWAY R J SABIN M J | 1987 | IEEE Trans on System Man and Cybernetics-Parts B:Cybernetics1987，17，5： | 1 |
| 20 | Safety of uvulopalatopharyogoplasty as outpatient surgery显示文摘 | Hathaway B Johnson J T | 2006 | Otolaryogol Head Neck Surg2006，134，4： | 1 |
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