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| 1 | 经皮冠状动脉介入的遥控操作:概念、验证和首次人体临床试验显示文摘OBJECTIVES: This study was designed to assess the feasibility and safety of a Remote Navigation System(RNS, NaviCath, Haifa, Israel) in which the angioplasty guidewire, the balloon, and the stent are navigated via a computerized system. BACKGROUND: Percutaneous coronary interventions(PCIs) are manually performed under fluoroscopic guidance, requiring lead protection for the operators. A system in which the operator can remotely, safely, and precisely navigate the procedure during PCI would have clear advantages. METHODS: The RNS involves a computer-controlled wire and delivery system navigator. Following preclinical validation, the system was assessed in patients undergoing single-vessel PCI. RESULTS: The study involved 18 patients(age 55.9 years, 16% women). The RNS successfully crossed lesions with the guidewire in 17 patients. The stent was then advanced by the advance/rotate mode and adequately positioned in 15 of 17 cases. Technical malfunction was encountered in three patients in whom the procedure was successfully completed manually. Direct stenting was employed in 10 of 18 patients,pre-dilation in 7 patients, and after-stent balloon dilation in 5 patients. The total fluoroscopy time for 17 RNS patients was compared with the corresponding time of 20 consecutive patients who underwent standard single lesion PCI. Fluoroscopy time was similar for both procedures, with 8.8± 4.8 min with the RNS versus 9.1± 3.5 min with the standard techniques(p=NS). Clinical success was 100% and technical success 94% for the guidewire and 83% for the overall procedure. CONCLUSIONS: The use of the RNS for guidewire, balloon, and stent manipulation during PCI appears safe and feasible for the treatment of patients with coronary stenosis. The system offers operator radiation safety and may enhance precision of stent placement and balloon dilation strategies. | Beyar R Gruberg L Deleanu D. 徐永城 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，2，5： | 3 |
| 2 | Acute renal failure requiring dialysis after percutaneous coronary interventions显示文摘 | Gruberg L Mehran R Dangas G | 2001 | Cathet Cardiovasc Interven2001，52，4： | 1 |
| 3 | Late stent thrombosis after implantation of a sirolimus-eluting stent显示文摘 | Kerner A Gruberg L Kapeliovich M | 2003 | Catheter Cardiovasc Interv2003，60，4： | 1 |
| 4 | The significance of persistent STelevation vensus early resolution of STsegement elevation after primary PTCA显示文摘 | Matetzky S Novikov M Gruberg L | 1999 | J Am Coll Cardiol1999，34，： | 1 |
| 5 | Carotid artery stenting in surgical high-risks patients显示文摘 | talabi M Gruberg L Pitchersky S | 2006 | Catheter Cardiovasc lnterv2006，67，4： | 1 |
| 6 | The impact of GP IIb/IIIa inhibitors druging primary percutaneous coronary intervention in acute myocardial infarction patients显示文摘 | Lavi S Gruberg L Kapcliovich M | 2005 | J Invasive Cardial2005，17，6： | 1 |
| 7 | The prognostic implications of further renal function deterioration within 48 h of interventional coronary procedures in patients with pre-existent chronic renal insufficiency显示文摘 | Gruberg L Mintz GS Mehran R | 2000 | J Am Coll Cardiol2000，36，5： | 1 |
| 8 | Troponin Positibe, CK - MB negative acute myocardial infarction: clinical, electrocardiographic and angiographic characteristics 显示文摘 | Gruberg L Sudarsky D Kerner A | 2005 | J Invasive Cardiol2005，20，3： | 1 |
| 9 | The impact of GP IIb/IIIa inhibitiors during primary percutaneous coronary intervention in acute myocardialinfarction patients显示文摘 | Lavi S Gruberg L Kapeliovich M | 2005 | J Invasive Cardiol2005，17，6： | 1 |
| 10 | The significance of persistent ST elevation versus early resolution of ST segment elevation after primary PTCA显示文摘 | Matetzky S Novikov M Gruberg L | 1999 | J Am Coil Cardiol1999，34，： | 1 |
| 11 | Platelet Glycoprotein IIb/IIIa Inhibitors during Percutaneous Coronary Interventions: A Pharmacological and Clinical Review 显示文摘 | ANNE G GRUBERG L | 2004 | Expert Opin Pharmacother2004，5，2： | 1 |
| 12 | Late stent thrombosis after implantation of a sirolimus-eluting stent显示文摘 | Kemer A Gruberg L Kapeliovich M | 2003 | Catheter and Cardiovascular Intervention2003，60，： | 1 |
| 13 | RMiocontrast- induced nephropathy and pereuta- neous coronary intervention: a review of preventive measures显示文摘 | Mintz EP Gruberg L | 2003 | Expert Opin Pharmaeothcr2003，4，5： | 1 |
| 14 | Incidence, Management and Outcome of Coronary Artery Perforation during Percutaneous Coronary Intervention显示文摘 | Gruberg L Pinnow E Hood R | 2000 | Am J Cardiol2000，86，： | 1 |
| 15 | Clinical outcome fol-lowing percutaneous coronary interventions in patients with chronic renal failure 显示文摘 | Gruberg L Dangas G Mehran R | 2002 | Catheter Cardiovasc Interv2002，55，1： | 1 |
| 16 | The impact of GP Ⅱ b/Ⅲ a inhibitors during primary percutaneous coronary intervention in acute myocardial infarction patients 显示文摘 | Lavi S Gruberg L Kapeliovich M | 2005 | J Invasive Cardiol2005，17，6： | 1 |
| 17 | Nucleus isthmi: its contribution to tectal acetylcholinesterase and choline acetyltranderase in the frog Rana pipiens显示文摘 | Wallace MT Ricciti AJ Gruberg ER | 1990 | Neuroscience1990，35，： | 1 |
| 18 | Acute renal failure requiring dialysis after percutaneous coronary interventions显示文摘 | Gruberg L Mehran R Dangas G | 2001 | Catheter Cardiovasc Interv2001，52，4： | 1 |
| 19 | The impact of GP Ⅱb/Ⅲa inhibitors during primary percutaneous coronary interventionin acute myocardial infarction patients显示文摘 | Lavi S Gruberg L Kapeliovich M | 2005 | J Incasive Cardiol2005，17，： | 1 |
| 20 | The impact of GP Ⅱb/Ⅲa inhibitors during prinrary percutaneous coronary intervention in acute myocardial infarction patients 显示文摘 | Lavi S Gruberg L Kapeliovich M | 2005 | J Invasive Cardiol2005，17，6： | 1 |
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