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| 1 | 学龄前肺功能轨迹是否延伸至成年期显示文摘成年早期的肺功能是个体死亡率和慢性阻塞性肺疾病(COPD)重要的决定因素。英国布里斯托大学医学院人口健康科学系的Henderson教授团队对3项人群出生队列研究的回顾性分析,探讨了学龄前到成年期肺功能发育的轨迹,及生命早期可能的影响因素。 | BELGRAVE D C M GRANELL R TURNERS W 孙莹(编译) | 2018 | 中国学校卫生2018，39，11： | 8 |
| 2 | Peroxisome proliferator-activated receptor γ agonist reduces the severity of post-ERCP pancreatitis in rats显示文摘AIM: To determine the effects of prophylactic peroxi-some proliferator-activated receptor (PPARγ) agonist administration in an experimental model of post-endoscopic retrograde cholangiopancreatography (post-ERCP) acute pancreatitis.METHODS: Post-ERCP pancreatitis was induced in male Wistar rats by infusion of contrast medium into the pancreatic duct. In additional group, rosiglitazone, a PPARγ agonist, was administered 1 h before infusion of contrast medium. Plasma and pancreas samples were obtained 6 h after the infusion.RESULTS: Infusion of contrast medium into the pan-creatic duct resulted in an inflammatory process characterized by increased lipase levels in plasma, and edema and myeloperoxidase activity (MPO) in pancreas. This result correlated with the activation of nuclear factor κB (NFκB) and the inducible NO synthase (iNOS) expression in pancreatic cells. Rosiglitazone reduced the increase in lipase and the level of edema and the increase in myeloperoxidase as well as the activation of NFκB and iNOS expression.CONCLUSION: A single oral dose of rosiglitazone, given 1 h before post-ERCP pancreatitis induction is effective in reducing the severity of the subsequent inflammatory process. The protective effect of rosiglitazone was associated with NFκB inhibition and the blockage of leukocyte infiltration in pancreas. | Emma Folch-Puy Susana Granell Juan L Iovanna Marc Barthet Daniel Closa | 2006 | World Journal of Gastroenterology2006，12，40： | 6 |
| 3 | Helping the Consumers and Producers of Standards,Repositories and Policies to Enable FAIR Data显示文摘Thousands of community-developed(meta)data guidelines,models,ontologies,schemas and formats have been created and implemented by several thousand data repositories and knowledge-bases,across all disciplines.These resources are necessary to meet government,funder and publisher expectations of greater transparency and access to and preservation of data related to research publications.This obligates researchers to ensure their data is FAIR,share their data using the appropriate standards,store their data in sustainable and community-adopted repositories,and to conform to funder and publisher data policies.FAIR data sharing also plays a key role in enabling researchers to evaluate,re-analyse and reproduce each other’s work.We can map the landscape of relationships between community-adopted standards and repositories,and the journal publisher and funder data policies that recommend their use.In this paper,we show how the work of the GO-FAIR FAIR Standards,Repositories and Policies(StRePo)Implementation Network serves as a central integration and cross-fertilisation point for the reuse of FAIR standards,repositories and data policies in general.Pivotal to this effort,the FAIRsharing,an endorsed flagship resource of the Research Data Alliance that maps the landscape of relationships between community-adopted standards and repositories,and the journal publisher and funder data policies that recommend their use.Lastly,we highlight a number of activities around FAIR tools,services and educational efforts to raise awareness and encourage participation. | Peter McQuilton Dominique Batista Oya Beyan Ramon Granell Simon Coles Massimiliano Izzo Allyson L.Lister Robert Pergl Philippe Rocca-Serra Ben Schaap Hugh Shanahan Milo Thurston Susanna-Assunta Sansone | 2020 | Data Intelligence2020，2，1： | 5 |
| 4 | Lymphomatoid papulosis associated with both severe hypereosinophilic syndrome and CD30positive large T-cell lymphoma显示文摘 | Granel B Serratrice J Swiader L | 2000 | Cancer2000，1589，10： | 1 |
| 5 | Circulating TNF-alpha and its soluble receptors during experimental acute pancreatitis显示文摘 | Granell S Pereda J Gomez-Cambronero L | 2004 | Cytokine2004，25，4： | 1 |
| 6 | Influence of portal blood on the development of systemic inflammation associated with experimental acute pancreatitis 显示文摘 | Hoyos S Granell S Heredia N | 2005 | Surgery2005，137，2： | 1 |
| 7 | Applications for bronchial blockers in thoracic surgery显示文摘 | GARC(I)A-GUASCH R CAMPOS J H GRANELL M | | 0，，09： | 1 |
| 8 | Transient early wheeze and lung function in early childhood associated with chronic obstructive pulmonary disease genes显示文摘 | Marjan Kerkhof H. Marike Boezen Raquel Granell Alet H. Wijga Bert Brunekreef Henri?tte A. Smit Johan C. de Jongste Carel Thijs Monique Mommers John Penders John Henderson Gerard H. Koppelman Dirkje S. Postma | 2014 | The Journal of Allergy and Clinical Immunology2014，，1： | 1 |
| 9 | Shaping digital earth applications through open innovation - setting the scene for a digital earth living lab显示文摘Science and policy increasingly request for sustainable development and growth.Similarly,Digital Earth undergoes a paradigm shift to an open platform that actively supports user engagement.While the public becomes able to contribute new content,we recognize a gap in user-driven validation,feedback and requirements capture,and innovative application development.Rather than defining Digital Earth applications top down,we see a need for methods and tools that will help building applications bottom up and driven by community needs.These should include a technology toolbox of geospatial and environ-mental enablers,which allow to access functional building blocks and content in multiple ways,but-equally important-enable the collaboration within partially unknown stakeholder networks.The validation and testing in real-life scenarios will be a central requirement when approaching the Digital Earth 2020 goals,which were articulated recently.We particularly argue to follow a Living Lab approach for co-creation and awareness rising in relation to environmental and geospatial matters.We explain why and how such a Digital Earth Living Lab could lead to a sustainable approach for developing,deploying,and using Digital Earth applications and suggest a paradigm shift for Virtual Globes becoming forums for research and innovation. | Sven Schade Carlos Granell | 2014 | International Journal of Digital Earth2014，7，7： | 1 |
| 10 | Mannan-binding lectin pathway deficiencies and invasive fungal infections following allogeneie stem cell transplantation显示文摘 | Granell M Urbano-Ispizua A Suarez B | 2006 | Exp Hematol2006，34，10： | 1 |
| 11 | Valproate-induced hyperam- monemic encephalopathy 显示文摘 | Granel B Gavaret M Le Baut X | 2011 | Rev Med Interne2011，32，6： | 1 |
| 12 | The plant homologue of the defender against apoptotic death gene is down-regulated during senescence of flower petals 显示文摘 | Orzdez D Granell A | 1997 | FEBS Letters1997，404，23： | 1 |
| 13 | Mothers' anxiety during pregnancy is associated with asthma in their children显示文摘 | Cookson H Granell R Joinson C Ben-Shlomo Y Henderson AJ | | 0，，： | 1 |
| 14 | Characterization of tomato cycling Dof factors reveals conserved and new functions in the control of flowering time and abiotic stress responses 显示文摘 | Corrales A R Nebauer S G Carrillo L Fernandez-Nohales P Marques J Renau-Morata B Granell A Pollmann S Vicente- Carbajosa J Molina R V Medina J | 2014 | Journal of Experimental Botany2014，65，4： | 1 |
| 15 | Serum cartilage oligo- meric matrix protein and other biomarker profiles in tib- iofemoral and patellofemoral osteoarthritis of the knee 显示文摘 | Sharif M Granell R Johansen J | 2006 | Rheumatology (Oxford)2006，45，5： | 1 |
| 16 | Flow cytometryanalysis of Leukocytes in induced sputum from asthmaticpatients显示文摘 | Vidal S Bellido Casado J Granel C | 2012 | Immunobiology2012，217，7： | 1 |
| 17 | Association between a CTGF gene polymorphism and systemic sclerosis in a French population 显示文摘 | Granel B Argiro L Hachulla E | 2010 | The Journal of Rheumatology2010，37，2： | 1 |
| 18 | Genome-wide association study of body mass index in 23 000 individuals with and without asthma 显示文摘 | Melen E Granell R Kogevinas M | 2013 | Clin Exp Allergy2013，43，4： | 1 |
| 19 | DNA Fragmentation is Regulated by Ethylene during Carpel Senesence in Pisum Sativum 显示文摘 | ORZAEZ D GRANELL A | 1997 | Plant J1997，11，： | 1 |
| 20 | Severe lower Iimbs Iymphedema following breast careinoma treatment revealing radiation ndueed constrictive pericarditis- a case report 显示文摘 | Granel B Gudy C Serratfice J | 2005 | Angilogy2005，56，1： | 1 |
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