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| 1 | 接受他汀治疗患者新发糖尿病风险:人群为基础的研究显示文摘目的 研究接受HMG-CoA还原酶抑制剂(他汀类药物)治疗的患者的新发糖尿病风险。设计 人群为基础的队列研究,以时间事件分析的方法评估各种他汀类药物应用和新发糖尿病风险的相关性分析。计算危害比(hazard ratios,HR)来确定他汀的种类及剂量与新发糖尿病的关系。 | Aleesa A Caner Tara Gomes Ximena Camacho David N Juurlink Baiju R Shah Muhammad M Mamdani 张秀珍(译) 骆斯慧(译) 翁建平(校) | 2013 | 英国医学杂志中文版2013，16，5： | 2 |
| 2 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 3 | Estimation in vivo of the body and carcass chemical composition of growing lambs by real-time ultrasonography显示文摘 | SILVA S R GOMES M J MAS-DA-SILVA A | 2005 | Journal of Animal Science2005，83，： | 1 |
| 4 | Novel metaphors appear anomalous at least momentarily:evidence from N400显示文摘 | Tartter V Gomes H Dubrovsky B Molholm S. Vala-Stewart R | | 0，，80： | 1 |
| 5 | Erros in ground distortions due to settlement trough adjustment显示文摘 | CELESTINO T B GOMES R A M P and BORTOLUCCI A A | 2000 | Tunneling and underground Space Technology2000，15，1： | 1 |
| 6 | Post-transplant diabetes melli- tus显示文摘 | Gomes M B Cobas R A | 2009 | Diabetol Metab Syndr2009，1，1： | 1 |
| 7 | Effect of dental surface treatment with Nd:YAG and Er:YAG lasers on bond strength of resin composite to recently bleached enamel显示文摘 | Rocha Gomes Torres C Caneppele TM Del Moral de Lazari R | 2012 | Laser Med Sci2012，27，4： | 1 |
| 8 | Low occurrence of occult hepatitis B virus infection and high frequency of hepatitis C virus genotype 3 in hepatocellular carcinoma in Brazil Brazilian 显示文摘 | RSM Alencarl MMS Gomes R Sitnik | 2008 | J Med and Biol Res2008，41，： | 1 |
| 9 | A Study of the Determinants of CEO Compensation in India显示文摘 | Ramaswamy K Veliyath R Gomes L | 2000 | Management International Review2000，40，2： | 1 |
| 10 | Gialpha3 pro- tein-coupled dopamine D3 receptor-mediated inhibition of renal NHE3 activity in SHR proximal tubular ceils is a PLC-PKC-mediated event 显示文摘 | PEDROSA R GOMES P HOPFER U | 2004 | Am J Physiol Renal Physiol2004，287，5： | 1 |
| 11 | Si3N4 and Si3N4/SiC composite rings for dynamic sealing of circulating fluids显示文摘 | Carrapichano J M Gomes J R | 2003 | Wear2003，255，： | 1 |
| 12 | Urinary 11-dehydro thromboxane B 2 levels in type 2 diabetic patients before and during aspirin intake显示文摘 | Lillian Harboe Gon?alves Luci Maria Sant'Ana Dusse Ana Paula Fernandes Karina Braga Gomes Mirelle Oliveira Sóter Michelle Teodoro Alves Kathryna Fontana Rodrigues Fernanda Rocha Freitas Flavia Komatsuzaki Marinez Oliveira Sousa Adriana Aparecida Bosco Gér | 2011 | Clinica Chimica Acta2011，，15： | 1 |
| 13 | An investiga- tion of the presence of specific anaerobic species in necrotic pri- mary teeth显示文摘 | Gomes GB Sarkis-Onofre R Bonow ML | 2013 | Braz Oral Res2013，27，2： | 1 |
| 14 | First isolation of the Stephanoascus ciferrii in feline otitis in Brazil 显示文摘 | Gomes Ados R Cabana A Osbrio Lda G et ai | 2014 | Braz J Microbiol2014，45，3： | 1 |
| 15 | Physical Distribution Service:A Fundamental Marketing Concept 显示文摘 | Mentzer J T Gomes R Krapfel R E | 1989 | Journal of the Academy of MarketingScience1989，17，4： | 1 |
| 16 | Supercritical fluid extraction of lipids from spent coffee grounds显示文摘 | Ricardo M C Joao F Gomes da Silva M D R | 2009 | Journal of Supercritical Fluids2009，51，： | 1 |
| 17 | Optimal freeway ramp metering using the asymmetric cell transmission model显示文摘 | Gomes G Horowitz R | 2006 | Transportation Research Part C2006，14，： | 1 |
| 18 | Hydrogen peroxide pre - treatment induces salt - stress acclimation in maize plants 显示文摘 | Neto A D de A Prisco J T Eneas - Filho J Medeiros J V R Gomes -Filho E | 2005 | Journal of Plant Physiology2005，162，10： | 1 |
| 19 | Beating versus arrested heart revascularization:evaluation of myocardial function in a prospective randomized study显示文摘 | Lloyd CT Gomes WJ | 1999 | Eur J Cardiothorac Surg1999，15，： | 1 |
| 20 | Effect of high-pressure treatment on the activity of some polyphenoloxidases显示文摘 | Gomes M R A Ledward D A | 1996 | Food Chemistry1996，56，1： | 1 |
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