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| 1 | National trends in resection of the distal pancreas显示文摘AIM:To investigate national trends in distal pancreatectomy(DP) through query of three national patient care databases.METHODS:From the Nationwide Inpatient Sample(NIS,2003-2009),the National Surgical Quality Improvement Project(NSQIP,2005-2010),and the Surveillance Epidemiology and End Results(SEER,2003-2009) databases using appropriate diagnostic and procedural codes we identified all patients with a diagnosis of a benign or malignant lesion of the body and/or tail of the pancreas that had undergone a partial or distal pancreatectomy.Utilization of laparoscopy was defined in NIS by the International Classification of Diseases,Ninth Revision correspondent procedure code;and in NSQIP by the exploratory laparoscopy or unlisted procedure current procedural terminology codes.In SEER,patients were identified by the International Classification of Diseases for Oncology,Third Edition diagnosis codes and the SEER Program Code Manual,third edition procedure codes.We analyzed the databases with respect to trends of inpatient outcome metrics,oncologic outcomes,and hospital volumes in patients with lesions of the neck and body of the pancreas that underwent operative resection.RESULTS:NIS,NSQIP and SEER identified 4242,2681 and 11 082 DP resections,respectively.Overall,laparoscopy was utilized in 15%(NIS) and 27%(NSQIP).No significant increase was seen over the course of the study.Resection was performed for malignancy in 59%(NIS) and 66%(NSQIP).Neither patient Body mass index nor comorbidities were associated with operative approach(P = 0.95 and P = 0.96,respectively).Mortality(3% vs 2%,P = 0.05) and reoperation(4% vs 4%,P = 1.0) was not different between laparoscopy and open groups.Overall complications(10% vs 15%,P < 0.001),hospital costs [44 741 dollars,interquartile range(IQR) 28 347-74 114 dollars vs 49 792 dollars,IQR 13 299-73 463,P = 0.02] and hospital length of stay(7 d,IQR 4-11 d vs 7 d,IQR 6-10,P < 0.001) were less when laparoscopy was utilized.One and two year survival after resection for malignancy were unchanged over the course of the study(ductal adenocarinoma 1-year 63.6% and 2-year 35.1%,P = 0.53;intraductal papillary mucinous neoplasm and nueroendocrine 1-year 90% and 2-year 84%,P = 0.25).The majority of resections were performed in teaching hospitals(77% NIS and 85% NSQIP),but minimally invasive surgery(MIS) was not more likely to be used in teaching hospitals(15% vs 14%,P = 0.26).Hospitals in the top decile for volume were more likely to be teaching hospitals than lower volume deciles(88% vs 43%,P < 0.001),but were no more likely to utilize MIS at resection.Complication rate in teaching and the top decile hospitals was not significantly decreased when compared to non-teaching(15% vs 14%,P = 0.72) and lower volume hospitals(14% vs 15%,P = 0.99).No difference was seen in the median number of lymph nodes and lymph node ratio in N1 disease when compared by year(P = 0.17 and P = 0.96,respectively).CONCLUSION:There appears to be an overall underutilization of laparoscopy for DP.Centralization does not appear to be occurring.Survival and lymph node harvest have not changed. | Armando Rosales-Velderrain Steven P Bowers Ross F Goldberg Tatyan M Clarke Mauricia A Buchanan John A Stauffer Horacio J Asbun | 2012 | World Journal of Gastroenterology2012，18，32： | 8 |
| 2 | Scaling behavlour of heartbeat intervals obtained by wavelet-based time-series analysis显示文摘 | Inanov P C h and Rosenblum M G and Peng C-K and Mietus J and Havlin S and Stanley H E and Goldberger A L | 1996 | Nature1996，383，： | 1 |
| 3 | Low-temperature wafer-scale productionof Zno nanowire aITays显示文摘 | Greene L E Law M Goldberger J Kim F Johnson J C Zhang Y F Saykally R J.Yang P D | | 0，，26： | 1 |
| 4 | In vivo osteochondrogenic potential of cultured cells derived from the periosteum 显示文摘 | NAKAHURA H BRUDER S P GOLDBERG V M | 1990 | Clin Orthop1990，259，： | 1 |
| 5 | The 1 450 nm diode laser for facial inflammatory acne vulgaris:Dose-response and 12-month follow-up study显示文摘 | Jih M H Friedman P M Goldberg L H | 2006 | JAm Acad Dermatol2006，55，1： | 1 |
| 6 | The Effects of Three Styles of Teaching on the Psychomotor Per- formance of Fifth Grade Children显示文摘 | GOLDBERGER M GEMEY P CHAMBERLAIN J | 1982 | Res Q Exerc Sport1982，53，2： | 1 |
| 7 | Chaperones and protein folding in the archaea显示文摘 | Large A T Goldberg M D Lund P A | 2009 | Biochem Soc Trans2009，37，1： | 1 |
| 8 | Amacrinesignaled loss of intrinsic axon growth ability by retinal ganglion cells显示文摘 | Goldberg J L Klassen M P Hua Y Barres B A | | 0，，5574： | 1 |
| 9 | In vitro effects of amylin on carbohydrate metabolism in liver cells 显示文摘 | Ciaraldi T P Goldberg M Odom R | 1992 | Diabetes1992，41，8： | 1 |
| 10 | Resveratrol:a molecule whose time has come and gone显示文摘 | SOLEAS G J DIAMANDIS E P GOLDBERG D M | 1997 | Clin Biochem1997，30，2： | 1 |
| 11 | Chaperones and protein folding in the archaea 显示文摘 | Large A T Goldberg M D Lund P A | 2009 | Biochena Soe Trans2009，37，： | 1 |
| 12 | Goods prices and exchange rates:What have we learned?显示文摘 | Goldberg P K Knetter M | 1997 | Journal of Economic Literature1997，，35： | 1 |
| 13 | The effect of implants loaded with autologous mesenchymal stem cells on the healing of canine semental bone defects显示文摘 | Bruder S P Kraus K H Goldberg B M | 1998 | J Bone Joint Surg Am1998，80，7： | 1 |
| 14 | Polymer directed nanocluster synthesis:Control of particle size and morphology显示文摘 | Tannenbaum R Zubris M Goldberg E P | 2005 | Macromolecules2005，38，10： | 1 |
| 15 | Measuring the Intensity of Competition in Export Markets 显示文摘 | Goldberg P K Knetter M | 1999 | Journal of International Economics1999，，147： | 1 |
| 16 | Measuring the intensity of competition in export markets显示文摘 | Goldberg P K Knetter M M | | 0，，01： | 1 |
| 17 | AIRS/ mission: Design, science objecrives, data products and processing system显示文摘 | Aumann H H Chahine M T Gautier C Goldberg M D Kalnay E Mcmillin L M Revereomb H Rosenkranz P W Smith W L Staelin D H AMSU/HSB on the Aqua Strow L L Susskind J | 2003 | IEEE Trans actions on Geoscience and Remote Sensing2003，41，： | 1 |
| 18 | Anther development:basic principles and practical application显示文摘 | GOLDBERG R B BEALES T P SANDERS P M | 1993 | Plant Cell1993，5，： | 1 |
| 19 | The effect of implants loaded with autologous mesenchymal stem cells on the healing of canine segmental bone defects显示文摘 | Bruder S P Kraus K H Goldberg V M | 1998 | J Bone Joint Surg Am1998，80，7： | 1 |
| 20 | Rate of antigen degradation by the ubiquitin-proteasome path- way influences MHC class 显示文摘 | GRANT E P MICHALEK M T GOLDBERG A L | 1995 | The Journal of Immunology1995，155，8： | 1 |
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