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| 1 | 发达国家纵向整合临床实习模式的发展及其对我国医学教育的启示显示文摘临床实习是医学生将理论知识转化为临床能力和深入临床环境学习的重要途径。纵向整合临床实习模式目前是一种创新性的临床教学方法和理念,它将连续性作为教学原则,很好地解决了原有临床实习中缺乏医疗连续性、课程连续性和教学指导连续性的问题,越来越多的医学院应用此种模式进行临床教学改革。本文对该实习模式的核心内涵、意义和哈佛剑桥模式及其发展与衍变进行阐述,并结合中国医学教育的实际需求进行分析,认为纵向整合临床实习模式可以提高我国临床医生培养质量,促进基层医疗人才队伍建设,增强住院医师规范化培训效果,有助于我国医学教育改革发展。 | 李鸿鹤 David A Hirsh Tara A Singh Yamini Saravanan Rachel Hathaway Bianca Shagrin Elizabeth Gaufberg Arundhati Ghosh 刘君 李扬龄 闻德亮 | 2020 | 中华医学教育杂志2020，40，9： | 10 |
| 2 | Effects of contact lens wearing on keratoconus:a confocal microscopy observation显示文摘AIM: To evaluate the corneal cell morphology of new keratoconus patients wearing two different types of rigid gas-permeable(RGP) contact lenses for 1y.METHODS: Thirty nine eyes of 39 new keratoconus patients were selected and randomly fitted with two types of RGP contact lenses.Group 1 had 21 eyes with regular rigid gas-permeable(RRGP) contact lens and rest 18 eyes were in group 2 with specially designed rigid gas-permeable(SRGP) contact lens.Corneal cell morphology was evaluated using a slit scanning confocal microscope at no-lens wear and after 1y of contact lens wearing.RESULTS: After 1y of contact lens wearing in group 1,the mean anterior and posterior stromal keratocyte density were significantly less(P=0.006 and P=0.001,respectively) compared to no-lens wear.The mean cell area of anterior and posterior stromal keratocyte were also significantly different(P=0.005 and P=0.001) from no-lens wear.The anterior and posterior stromal haze increased by 18.74% and 23.81%,respectively after 1y of contact lens wearing.Whereas in group 2,statistically significant changes were observed only in cell density & area of anterior stroma(P=0.001 and P=0.001,respectively) after 1y.While,level of anterior and posterior stromal haze increased by 16.67% and 11.11% after 1y of contact lens wearing.Polymegathism and pleomorphism also increased after 1y of contact lens wearing in both the contact lens groups.CONCLUSION: Confocal microscopy observation shows the significant alterations in corneal cell morphology of keratoconic corneas wearing contact lenses especially in group 1.The type of contact lens must be carefully selected to minimize changes in corneal cell morphology. | Somnath Ghosh Haliza A Mutalib Sharanjeet Kaur Rituparna Ghoshal Shamala Retnasabapathy | 2017 | International Journal of Ophthalmology(English edition)2017，10，2： | 4 |
| 3 | WISE USE OF WETLAND FOR SUSTAINABLE LIVELIHOOD THROUGH PARTICIPATORY APPROACH:A CASE OF ADAPTING TO CLIMATE CHANGE显示文摘The facts showed that the number of unemployment people is increasing and a large part of them live in the low-lying areas to be facing the challenge from impacts of climate change. So adaptive capacity of the poverty level for sustainable livelihood in vulnerable wetlands is related to coping with local climate change. This paper focuses on soil-less agriculture (Hydroponics) as an alternative source of livelihood means for the communities having no lands for cultivation. Approximately half of Bangladesh is covered with wetlands. The prospect of enormous productivity lies in the development of wetland resources. The soil-less agriculture is an indigenous practice in the middle of southwestern part of Bangladesh. The people who lives within the wetland ecosystems uses locally available paddy straws, water hyacinths and various invasively aquatic plants for making the floating mat or organic bed on which crops, vegetables and seedlings are grown. The productivity of this farming system is much higher than that of terrestrials agricultural and the system can support fisheries of open water. The compost generated from organic refuse bed is a kind of enriched nutrient and can act as a soil conditioner. It would be a major source of nutrients in aquaculture as well. The system is capable to ensure more agriculture production by restoring wetlands from aquatic invasive plant. In addition, the technology included of the system is friendly to ecosystem of wetlands. | Haq A H M Rezaul Tapan Kumar Ghosal Pritam Ghosh M Aminul Islam | 2005 | 湿地科学2005，3，3： | 4 |
| 4 | B lymphocytes regulate airway granulocytic inflammation and cytokine production in a murine model of fungal allergic asthma显示文摘到真菌的促进感受性经常导致是特别地困难的临床上设法的气喘的一种严重形式,导致在这些病人的增加的病态和住院。尽管 B 淋巴细胞可能通过 IgE 的生产加重气喘症状,这些房间可能也在对吸入的真菌的保护的反应是重要的。通过 cytokine 版本和 T 房间相互作用,这些淋巴细胞可能也影响航线墙纤维变性的发展和维护。J H −/− 老鼠为抗体的重链部件缺乏 JH 基因,它为 B 房间功能和幸存是批评的。这些动物在很多有免疫力的回答便于 B 淋巴细胞的角色的说明;然而, J H −/− 老鼠没被用来学习真菌的过敏症。在这研究,我们用曲霉属菌 fumigatus 检验了 B 淋巴细胞的角色模仿被环境真菌的暴露触发的人的航线疾病的鼠科的真菌的高空过敏症模型。我们在敏化的野类型的 BALB/c 和 J 暴露于的 H −/− 老鼠重复了真菌的暴露并且没在大航线附近在航线 hyperresponsiveness,全面肺的发炎或骨胶原免职发现差别。然而, Th2 类型 cytokines IL-4 和 IL-13 的层次显著地在 J 相对 BALB/c 控制的 H −/− 鼠标。由对比,煽动性的 cytokines IL-17A 和 IL-6 的层次显著地在 J H −/− 动物,并且有显著地更柔韧的航线嗜曙红血球过多和 neutrophilia 比在控制动物。一起拿,这些调查结果表明淋巴细胞帮助在肺的分隔空间调整 granulocytic 回答到真菌的暴露的那 B。 | Sumit Ghosh Scott A Hoselton Scott V Asbach Breanne N Steffan Steve B Wanjara Glenn P Dorsam Jane M Schuh | 2015 | Cellular & Molecular Immunology2015，12，2： | 2 |
| 5 | Cathode shape prediction in electrochemical machining using a simulated cut-and-try procedure 显示文摘 | Bhattacharyya S Ghosh A Mallik A K | 1997 | Journal of Materials Processing Technology1997，66，： | 2 |
| 6 | Forking genetic algorithms: GAs with search space division schemes 显示文摘 | Tsntsui S Fujimoto Y Ghosh A | 1997 | Evolutionary computation1997，5，1： | 2 |
| 7 | Relationships of working conditions and individual characteristics to occupational injuries: a case-control study in coal miners显示文摘 | GHOSH A K BHATrACHERjEE A CHAU N | 2004 | J Occup Health2004，46，6： | 1 |
| 8 | DeveloPment of an animal model of hepatic fibrosis by excretory - secretory antigen of Ascaris suum显示文摘 | Antra A Chowdhury A Ghosh A Mazumder DN | 2000 | Indian J Gastroenterol2000，19，3： | 1 |
| 9 | Methylglyoxal increase in uremia with special reference to snakebite-mediated acute renal failure 显示文摘 | Mukhopadhyay S Ghosh A Kar M | 2008 | Clin Chim Acta2008，391，12： | 1 |
| 10 | Analytical model for time to covet cracking in RC structures due to rebar corrosion显示文摘 | BHARGAVA K GHOSH A K MORI Y | 2006 | Nuclear Engineering and Design2006，，236： | 1 |
| 11 | Simplified synthesis of single-walled carbon nanotubes from a botanical hydrocarbon : Turpentine oil 显示文摘 | Ghosh P Soga T Afre R A | 2008 | Journal of alloys and compounds2008，462，12： | 1 |
| 12 | Design of heat exchanger networks using randomized algorithm 显示文摘 | PARIYANI A GUPTA A GHOSH P | 2006 | Computers and Chemical Engineering2006，30，67： | 1 |
| 13 | Optimization of mettbrmin HC1 500 mg sustained release matrix tablets using Artificial Neural Network ( ANN ) based on Multilayer Perceptrons (MLP) model显示文摘 | Mandal U Gowda V Ghosh A | 2008 | Chem Pharm Bull (Tokyo)2008，56，2： | 1 |
| 14 | Selenium capture using sorbent powers: mechanism of sorption by hydrated lime显示文摘 | A Ghosh Dastidar S mahdi | 1996 | Environ Sci Technol1996，30，： | 1 |
| 15 | An approach to novel polyamidoamine (PAMAM) side chain dendritic polyesterurethane (SCDPEU) block copolymer architectures显示文摘 | Ghosh S Banthia A | 2003 | Euro Polym J2003，39，： | 1 |
| 16 | Role of fabric reinforcement on the low amplitude oscillating wear of polyetherimide composites显示文摘 | Bijwe J Indumathi J Ghosh A K | 2004 | Wear2004，256，： | 1 |
| 17 | Microsatllites for linkage analysis of genetic traits显示文摘 | Hearne C M Ghosh S Todd J A | 1992 | Trends in Genetic1992，8，： | 1 |
| 18 | Biosynthesis of bacterial glycogen显示文摘 | Kumar A Ghosh P Lee Y M | 1989 | J of Biol Chem1989，264，10： | 1 |
| 19 | Effect of combined use of nonionic surfactant on formation of oil-in-water mlcroemulsions显示文摘 | Li P Ghosh A Wagner R F | 2005 | Int J Pharm2005，288，1： | 1 |
| 20 | Approximation methods in multidisciplinary analysis and optimization: a panel discussion 显示文摘 | Simpson T W Booker A J Ghosh D | 2004 | Structural and Multidisciplinary Optimization2004，27，5： | 1 |
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