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| 1 | SOFC technology development at Rolls-Royce显示文摘 | Gardner F J Day M J Brandon N P | 2000 | J Power Sources2000，86，： | 2 |
| 2 | Increased presence of effector lymphocytes during Helicobacter hepaticus-induced colitis显示文摘AIM:To identify and characterize drosophila mothers against decapentaplegic(SMAD)3-dependent changes in immune cell populations following infection with Helicobacter hepaticus(H.hepaticus).METHODS:SMAD3 -/-(n=19)and colitis-resistant SMAD3+/-(n=24)mice(8-10 wk of age)were in-fected with H.hepaticus and changes in immune cell populations[T lymphocytes,natural killer(NK)cells,T regulatory cells]were measured in the spleen and mesenteric lymph nodes(MsLNs)at 0 d,3 d,7 d and 28 d post-infection using flow cytometry.Genotypedependent changes in T lymphocytes and granzyme B+ cells were also assessed after 28 d in proximal colon tissue using immunohistochemistry.RESULTS:As previously observed,SMAD3 -/-,but not SMAD3+/-mice,developed colitis,peaking at 4 wk post-infection.No significant changes in T cell subsets were observed in the spleen or in the MsLNs between genotypes at any time point.However,CD4+and CD8+/ CD62Llo cells,an effector T lymphocyte population,as well as NK cells(NKp46/DX5+)were significantly higher in the MsLNs of SMAD3-/-mice at 7 d and 28 d post-infection.In the colon,a higher number of CD3+cells were present in SMAD3-/-compared to SMAD3+/-mice at baseline,which did not significantly change during infection.However,the number of granzyme B+cells,a marker of cytolytic lymphocytes,significantly increased in SMAD3-/-mice 28 d post-infection compared to both SMAD3+/-mice and to baseline values.This was consistent with more severe colitis development in these animals.CONCLUSION:Data suggest that defects in SMAD3 signaling increase susceptibility to H.hepaticus-induced colitis through aberrant activation and/or dysregulation of effector lymphocytes. | Sarah J McCaskey Elizabeth A Rondini Jonathan F Clinthorne Ingeborg M Langohr Elizabeth M Gardner Jenifer I Fenton | 2012 | World Journal of Gastroenterology2012，18，13： | 2 |
| 3 | Design, modelling and test results of the AWS PM linear generator 显示文摘 | PPLINDER I H DAMEN M E C GARDNER F | 2005 | Euro Trans Electr Power2005，15，： | 1 |
| 4 | Towards a full model of second language learning, an empirical investigation显示文摘 | Gardner R C Trembley P F Masgoret A M | 1997 | The Modem Language Journal1997，，81： | 1 |
| 5 | Interpolation in digital modems-part I: fundamentals 显示文摘 | GARDNER F M | 1993 | IEEE Trans on communication1993，41，5： | 1 |
| 6 | Linear PM generator system for wave energy conversion in the AWS显示文摘 | POLINDER H DAMEN M E C GARDNER F | | 0，，03： | 1 |
| 7 | Interpolation in Digital Modems-Part I:Fundamentals显示文摘 | GARDNER F M | | 0，，03： | 1 |
| 8 | An experimental investigation of factors affecting elastic wave velocities in porous media显示文摘 | Wyllie M R J Gregory A R Gardner G H F | 1958 | Geophysics1958，23，： | 1 |
| 9 | Interpolation in Digital Modems-PartII:Implementation and Performance显示文摘 | ERUP L GARDNER F M | | 0，，06： | 1 |
| 10 | A BPSK/QPSK Timing Error Detector for Sampled Receivers显示文摘 | Gardner F M | 1986 | lEEE Transactions on Communica tions1986，34，05： | 1 |
| 11 | Hangup in phase-lock loops显示文摘 | Gardner F M | 1977 | IEEE Trans on Commun1977，25，10： | 1 |
| 12 | Swainsonine-induced lysosomal storage disease in goats caused by the ingestion of Turbina cordata in northeastern Brazil显示文摘 | Dantasa A F M Riet-Correaa F Gardner D R | 2007 | Toxicon2007，49，： | 1 |
| 13 | Uni- pedicular balloon kyphoplasty for the treatment of osteo- porotic vertebral compression fractures:early results 显示文摘 | Papadopoulos EC Edobor-Osula F Gardner M J et a/ | 2008 | J Spinal Disord Tech2008，21，8： | 1 |
| 14 | Interpolation in digital modems - part I: Fun-damentals显示文摘 | Gardner F M | 1993 | IEEE Transaction On Communications1993，41，3： | 1 |
| 15 | An Experimental Investigation of Factors Affecting Elastic Wave Velocity Porous Media显示文摘 | Wyllie M R J Gardner G H F | 1958 | Geophysics1958，23，3： | 1 |
| 16 | Clinical assessment of effects of botanical supplementation on cytochrome P450 phenotypes in the elderly: St John' swort, garlic oil Panax ginseng and ginkgo biloba 显示文摘 | GURLEY B J GARDNER S F HUBBARD M A | 2005 | Drugs Aging2005，22，6： | 1 |
| 17 | Unipe- dicular balloon kyphoplasty for the treatment of osteoporotic verte- bral compression fractures : early results显示文摘 | Papadopoulos EC Edobor-Osula F Gardner M J | 2008 | J Spinal Disord Tech2008，21，8： | 1 |
| 18 | Interpolation in digital modem s_Part Ⅰ Fundamentals显示文摘 | Gardner F M | 1993 | IEEE T rans commun1993，41，3： | 1 |
| 19 | Charge-pump phase-locked loops 显示文摘 | GARDNER F M | 1980 | IEEE Trans Communications1980，28，11： | 1 |
| 20 | Cytochrome P450 phenotypic ratios for predicting herb-drug interactions in humans 显示文摘 | GURLEY B J GARDNERS F HUBBARD M A | 2002 | Clin Pharm Ther2002，72，3： | 1 |
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