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| 1 | Long-term safety of lamivudine treatment in patients with chronic hepatitis B显示文摘 | Anna S.F Lok Ching-Lung Lai Nancy Leung Guang-Bi Yao Zhen-Yu Cui Eugene R Schiff Jules L Dienstag E.Jenny Heathcote Nancy R Little Dorothea A Griffiths Stephen D Gardner Mary Castiglia | 2003 | Gastroenterology2003，，6： | 3 |
| 2 | Long-term safety of lamivudine treatment in patients with chronic hepatitis B显示文摘 | Anna S.F Lok Ching-Lung Lai Nancy Leung Guang-Bi Yao Zhen-Yu Cui Eugene R Schiff Jules L Dienstag E.Jenny Heathcote Nancy R Little Dorothea A Griffiths Stephen D Gardner Mary Castiglia | 2003 | Gastroenterology2003，，6： | 2 |
| 3 | Diabetic Retinopathy显示文摘 | Thomas W Gardner David A Antonetti Alistair J Barber Kathryn F LaNoue Steven W Levison | 2002 | Survey of Ophthalmology2002，，： | 2 |
| 4 | Increased presence of effector lymphocytes during Helicobacter hepaticus-induced colitis显示文摘AIM:To identify and characterize drosophila mothers against decapentaplegic(SMAD)3-dependent changes in immune cell populations following infection with Helicobacter hepaticus(H.hepaticus).METHODS:SMAD3 -/-(n=19)and colitis-resistant SMAD3+/-(n=24)mice(8-10 wk of age)were in-fected with H.hepaticus and changes in immune cell populations[T lymphocytes,natural killer(NK)cells,T regulatory cells]were measured in the spleen and mesenteric lymph nodes(MsLNs)at 0 d,3 d,7 d and 28 d post-infection using flow cytometry.Genotypedependent changes in T lymphocytes and granzyme B+ cells were also assessed after 28 d in proximal colon tissue using immunohistochemistry.RESULTS:As previously observed,SMAD3 -/-,but not SMAD3+/-mice,developed colitis,peaking at 4 wk post-infection.No significant changes in T cell subsets were observed in the spleen or in the MsLNs between genotypes at any time point.However,CD4+and CD8+/ CD62Llo cells,an effector T lymphocyte population,as well as NK cells(NKp46/DX5+)were significantly higher in the MsLNs of SMAD3-/-mice at 7 d and 28 d post-infection.In the colon,a higher number of CD3+cells were present in SMAD3-/-compared to SMAD3+/-mice at baseline,which did not significantly change during infection.However,the number of granzyme B+cells,a marker of cytolytic lymphocytes,significantly increased in SMAD3-/-mice 28 d post-infection compared to both SMAD3+/-mice and to baseline values.This was consistent with more severe colitis development in these animals.CONCLUSION:Data suggest that defects in SMAD3 signaling increase susceptibility to H.hepaticus-induced colitis through aberrant activation and/or dysregulation of effector lymphocytes. | Sarah J McCaskey Elizabeth A Rondini Jonathan F Clinthorne Ingeborg M Langohr Elizabeth M Gardner Jenifer I Fenton | 2012 | World Journal of Gastroenterology2012，18，13： | 2 |
| 5 | Elastic wave velocities in heterogeneous and porous media 显示文摘 | Wyllie M R J Gregory A R Gardner L W | 1956 | Geophysics1956，21，1： | 1 |
| 6 | Regulation of human cytotrophoblast morphogenesis by hepatocyte growth factor/scatter factor 显示文摘 | Dokras A Gardner LMG Elisabeth AS | 2001 | Biol Reprod2001，65，： | 1 |
| 7 | Preliminary studies on K and L coincidence spectroscopy for optimizing the in vivo XRF measurement of lead in bone显示文摘 | Guo W Gardner R P Metwally W A | 2004 | Nucl Instr and Meth in Phys Res B2004，213，： | 1 |
| 8 | Organic nitrogen mineralization and substrate limitation of bacteria in Lake Michigan显示文摘 | Gardner W S Chandler J F Laird A G | 1989 | Limnol Oceanogr1989，34，2： | 1 |
| 9 | Formation velocity and density-The diagnostic basis for stratigraphic traps 显示文摘 | Gardner G H F Gardner L W Gregory A R | 1974 | Geophysics1974，39，6： | 1 |
| 10 | One- class novelty detection for seizure analysis from intracranial EEG 显示文摘 | GARDNER A B KRIEGER A VACHTSEVANOS G | 2006 | Journal of Machine Learning Research2006，7，： | 1 |
| 11 | Characterization of cvclostarionary random signal processes显示文摘 | GARDNER N A | 1999 | IEEE Transaction on Im formation Theory1999，21，： | 1 |
| 12 | Hemoglobins dioxygenate nitric oxide with high fidelity显示文摘 | Gardner P R Gardner A M Brashear W T | 2006 | J Inorg Biochem2006，100，4： | 1 |
| 13 | Comprehensive fall prevention programs across settings: a review of the literature 显示文摘 | MacCulloch PA Gardner T Bonner A | 2007 | Geriatr Nurs2007，28，5： | 1 |
| 14 | Experiments on stainless steel hollow sections part 1 : Material and cross sectional behaviour 显示文摘 | Gardner L Nethereot D A | 2004 | Journal of Constructional Steel Research2004，60，9： | 1 |
| 15 | Transforming Growth Factor-β1 ( TGF-β1 ) Driven Epithelial to Mesenchymal Transition (EMT) is Accentuated by Tumour Necrosis Factor α (TNFα) via Crosstalk Between the SMAD and NF-KB Pathways 显示文摘 | Borthwick LA Gardner A De Soyza A | 2012 | Cancer Microenviron2012，5，1： | 1 |
| 16 | Fixation of posterior malleolar fractures provides greater syndesmotic stability显示文摘 | Gardner M J Brodsky A Briggs SM | 2006 | Clin Orthop Relat Res2006，447，： | 1 |
| 17 | DIET AWSUM: A fluctuation-based deconvolution technique for enhancing signal-to-noise ratio and resolution显示文摘 | Gardner S D Wagstaff R A | 1997 | IEEE journal of Oceanic Engineering1997，22，1： | 1 |
| 18 | Spectral correlation of modulated signals:part I-analog modulation显示文摘 | GARDNER W A | 1987 | IEEE Transactions on Communications1987，35，6： | 1 |
| 19 | The spectral Correlation Theory of Cyclc-Stationary Time-Series 显示文摘 | W A GARDNER | 1986 | Signal processing1986，11，： | 1 |
| 20 | Extreme population differences across Neuregulin 1 gene,with implications for association studies显示文摘 | Gardner M González-Neira A Lao O | 2006 | Mol Psychiatry2006，11，1： | 1 |
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