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| 1 | Production of proinflammatory cytokines in the human THP-1 monocyte cell line following induction by Tp0751,a recombinant protein of Treponema pallidum显示文摘The tissue destruction characteristic of syphilis infection may be caused by inflammation due to Treponema pallidum and the ensuing immune responses to the pathogen.T.pallidum membrane proteins are thought to be potent inducers of inflammation during the early stages of infection.However,the actual membrane proteins that induce inflammatory cytokine production are not known,nor are the molecular mechanisms responsible for triggering and sustaining the inflammatory cascades.In the present study,Tp0751 recombinant protein from T.pallidum was found to induce the production of proinflammatory cytokines,including TNF-α,IL-1βand IL-6,in a THP-1 human monocyte cell line.The signal transduction pathways involved in the production of these cytokines were then further investigated.No inhibition of TNF-a,IL-1β,or IL-6 production was observed following treatment with the SAPK/JNK specific inhibitor SP600125 or with an ERK inhibitor PD98059.By contrast,anti-TLR2 mAb,anti-CD14 mAb,and the p38 inhibitor SB203580 significantly inhibited the production of all three cytokines.In addition,pyrrolidine dithiocarbamate (PDTC),a specific inhibitor of NF-κB,profoundly inhibited the production of these cytokines.Tp0751 treatment strongly activated NF-κB,as revealed by Western blotting.However,NF-κB translocation was significantly inhibited by treatment with PDTC.These results indicated that TLR2,CD14,MAPKs/p38,and NF-κB might be implicated in the inflammatory reaction caused by T.pallidum infection. | LIU ShuangQuan1,2,WANG ShiPing1,WU YiMou3,ZHAO FeiJun3,ZENG TieBing3,ZHANG YueJun3,ZHANG QiuGui2 & GAO DongMei1 1 Department of Parasitology,Xiangya School of Medicine,Central South University,Changsha 410078 ,China 2 The First Affiliated Hospital,University of South China,Hengyan 421001,China 3 Department of Microbiology and Immunology,University of South China,Hengyan 421001,China | 2010 | Science China(Life Sciences)2010，53，2： | 28 |
| 2 | Total alkyl dibenzothiophenes content tracing the filling pathway of condensate reservoir in the Fushan Depression,South China Sea显示文摘The condensates are generally characterized by high maturity,low concentration of steranes and ter-panes biomarkers and low content of non-hydrocarbon fraction. In this case commonly used steranes,terpanes and carbazoles parameters cannot be effectively applied in the reservoir-filling tracing. The hydrogen bond formed by sulfur atom in the dibenzothiophenes (DBTs) results in molecule adsorption and fractionation during oil migration in reservoir. Like carbazoles,total DBTs content decreases with the increasing of oil migration distance. Therefore,a new parameter——total DBTs content is proposed to be used to trace the oil migration orientation and filling pathway. In present study,total DBTs con-tents of condensates and light oils are obtained by adding internal standard——eight deuterium atoms substituted DBT during Gas Chromatography-Mass Spectrometry analysis of aromatic fraction. Except for a few samples with much lower content of non-hydrocarbon fraction,the total DBTs content shows a fine positive correlation with that of carbazoles. Large errors can be caused in the process of pyrrolic nitrogen compounds separation. The application of this new parameter in the Fushan Depression of Beibu Gulf Basin,South China Sea indicates that this parameter is a reliable one to trace filling pathway in condensate reservoirs. Combined with other DBTs-related parameters,such as 4-/1-methydibenzo-thiophene and 2,4-/1,4-dimethyldibenzothiophene,oil migration orientation and filling pathway of the Fushan Depression was determined. The accumulations of Huachang oil field in the Fushan Depres-sion are mainly migrated and charged from northeast to southeast along the Huachang uplift. It can be predicated that the light oil and condensates in the Huachang oil field should be sourced from the source kitchen at the Bailian Sag. It shows that total DBTs content is an effective parameter to tracing oil migration orientation and filling pathway. | LI MeiJun1,WANG TieGuan1,LIU Ju2,ZHANG MeiZhu2,LU Hong3,MA QinLin2 & GAO LiHui2 1 State Key Laboratory of Petroleum Resources and Prospecting,Earth Sciences and Geoinformatics School,China University of Petroleum,Beijing 102249,China 2 Southern Oil Exploration and Development Company,PetroChina,Guangzhou 510640,China 3 Guangzhou Institute of Geochemistry,Chinese Academy of Sciences,Guangzhou 510240,China | 2008 | Science China Earth Sciences2008，51，S2： | 24 |
| 3 | AtHsfA2 modulates expression of stress responsive genes and enhances tolerance to heat and oxidative stress in Arabidopsis显示文摘There is increasing evidence for considerable interlinking between the responses to heat stress and oxidative stress, and recent researches suggest heat shock transcription factors (Hsfs) play an important role in linking heat shock with oxidative stress signals. In this paper, we present evidence that AtHsfA2 modulated expression of stress responsive genes and enhanced tolerance to heat and oxidative stress in Arabidopsis. Using Northern blot and quantitative RT-PCR analysis, we demonstrated that the expression of AtHsfA2 was induced by not only HS but also oxidative stress. By functional analysis of AtHsfA2 knockout mutants and AtHsfA2 overexpressing transgenic plants, we also demonstrated that the mutants displayed reduced the basal and acquired thermotolerance as well as oxidative stress tolerance but the overexpression lines displayed increased tolerance to these stress. The phenotypes correlated with the expres-sion of some Hsps and APX1, ion leakage, H2O2 level and degree of oxidative injuries. These results showed that, by modulated expression of stress responsive genes, AtHsfA2 enhanced tolerance to heat and oxidative stress in Arabidopsis. So we suggest that AtHsfA2 plays an im-portant role in linking heat shock with oxidative stress signals. | LI Chunguang1,2, CHEN Qijun1, GAO Xinqi1,3, QI Bishu1, CHEN Naizhi1, XU Shouming1, CHEN Jia1 & WANG Xuechen1 1. State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing 100094, China 2. Department of Industry Engineering, Zhengzhou Institute of Aeronautic Industry Management, Zhengzhou 450015, China 3. College of Life Science, Qufu Normal University, Qufu Shandong 273165, China | 2005 | Science China(Life Sciences)2005，48，6： | 23 |
| 4 | Study of ozone “weekend effect” in Shanghai显示文摘Analysis of observed ozone data in 2006 from five monitoring sites (Xujiahui, Chongming, Baoshan, Pudong, Jinshan) in Shanghai reveals that ozone (O_3) concentrations in Xujiahui are higher at week-ends than those on weekdays, despite the fact that emissions of ozone precursor substances, such as oxides of nitrogen (NOx), carbon monoxide (CO) and volatile organic compounds (VOCs) are lower at weekends than those on weekdays. The possible chemical cause of ozone 'weekend effect' is that NO_2/NO ratio increases at weekends by 25.61% compared with those on weekdays. In addition, because of an average 12.13% reduction in NOx (NO + NO_2) in the early morning (05:00-09:00) at weekends compared with that on weekdays, the ozone inhibition period ends 0.5 h earlier at weekends resulting in the longer duration of ozone accumulation and the higher ozone production rate. The rate of ozone production is a function of VOCs and NOx in the atmosphere. VOCs/NOx ratio in Xujiahui is 4.55 at weekends, and 4.37 on weekdays, belonging to the 'NOx-limited'. The increasing VOCs/NOx ratio at weekends leads to ozone enhancement from 73 ppbv to 80 ppbv, which are consistent with ozone 'weekend effect' in Xujiahui. Furthermore, combining with MICAPS cloud amount data, the fact that ozone 'weekend effect' in Xujiahui weakens gradually along with the increasing of cloud amount indicates that ozone photochemical production leads to ozone 'weekend effect' in Xujiahui of Shanghai. | TANG WenYuan1↑, ZHAO ChunSheng1, GENG FuHai1,2, PENG Li2, ZHOU GuangQiang2, GAO Wei2, XU JianMing2 & TIE XueXi2,3 1 Department of Atmospheric Science, School of Physics, Peking University, Beijing 100871, China 2 Atmospheric Chemistry Laboratory of Shanghai Meteorological Bureau, Shanghai 200030, China 3 Atmospheric Chemistry Division, NCAR, Boulder CO 80301, USA | 2008 | Science China Earth Sciences2008，51，9： | 23 |
| 5 | Geochemistry of high-Mg andesites from the early Cretaceous Yixian Formation, western Liaoning: Implications for lower crustal delamination and Sr/Y variations显示文摘85 volcanic rocks of the Yixian Formation from the Sihetun type section were collected and analyzed for geochemical and isotopic compositions. Major element compositions indicate that the Sihetun volcanic rocks are high magnesium andesites with some basalts occurring at the bottom of section. The Sihetun high magnesium andesites (SiO2 = 52.82―59.31wt%, Al2O3 = 14.15―16.35wt%) show many characteristics of adakites such as depletion in heavy rare-earth elements (HREE; Yb = 1.03―1.88 μg/g) and Y(12―20 μg/g) and high Sr (620―1323 μg/g) and Sr/Y(32―88), with high LaN/YbN ratio (10―25). They share similar major and trace element characteristics to volcanic rocks from the Xinglonggou Formation except their lower Nd isotope ratios (143Nd/144Nd (130Ma) = 0.5118―0.5119, ε Nd (130Ma) = ?11.6―?13.8, 87Sr/86Sr (130 Ma) = 0.7058―0.7064. They were in- terpreted in a way that eclogite that formed at the base of thickened Archean lower crust of the North China craton foundered into the convecting mantle and subsequently melted and interacted with peridotite. However, compared to the Xinglonggou volcanic rocks, the source of the Sihetun magma contained more ancient continental crustal material in order to explain its evolved Nd isotopes. The age of the Sihetun Formation was 120 to 130 Ma, and this indicates that delamination lasted to the early Cretaceous period. The Sr contents and Sr/Y ratios of the Sihetun high-Mg andesites show sig- nificant negative correlations with SiO2 for samples with SiO2 > 56%. These suggest that the Sr and Sr/Y values were reduced due to fractional crystallization of plagioclase. Accordingly, the effect of crystallization on volcanic Sr and Sr/Y ratio has to be taken into account. | WANG Xiaorui1, GAO Shan1,2, LIU Xiaoming1, YUAN Honglin1, HU Zhaochu1, ZHANG Hong1,3 & WANG Xuance4 1. State Key Laboratory of Continental Dynamics, Department of Geology, Northwest University, Xi`an 710069, China 2. State Key Laboratory of Geological Processes and Mineral Resources, China University of Geosciences, Wuhan 430074, China 3. Shenyang Institute of Geology and Mineral Resources, Shenyang 110032, China 4. Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China | 2006 | Science China Earth Sciences2006，49，9： | 19 |
| 6 | Forecasting the summer rainfall in North China using the year-to-year increment approach显示文摘A new approach to forecasting the year-to-year increment of rainfall in North China in July-August (JA) is proposed. DY is defined as the difference of a variable between the current year and the preceding year (year-to-year increment). NR denotes the seasonal mean precipitation rate over North China in JA. After analyzing the atmospheric circulation anomalies associated with the DY of NR, five key predictors for the DY of NR have been identified. The prediction model for the DY of NR is established by using multi-linear regression method and the NR is obtained (the current forecasted DY of NR added to the preceding observed NR). The prediction model shows a high correlation coefficient (0.8) between the simulated and the observed DY of NR throughout period 1965-1999, with an average relative root mean square error of 19% for the percentage of precipitation rate anomaly over North China. The prediction model makes a hindcast for 2000-2007, with an average relative root mean square error of 21% for the percentage of precipitation rate anomaly over North China. The model reproduces the downward trend of the percentage of precipitation rate anomaly over North China during 1965-2006. Because the current operational prediction models of the summer precipitation have average forecast scores of 60%-70%, it has been more difficult to forecast the summer rainfall over North China. Thus this new approach for predicting the year-to-year increment of the summer precipitation (and hence the summer precipitation itself) has the potential to significantly improve operational forecasting skill for summer precipitation. | FAN Ke1, LIN MeiJing1,2 & GAO YuZhong3 1 Nansen-Zhu International Research Center, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100029, China 2 Graduate University of the Chinese Academy of Sciences, Beijing 100049, China 3 Heilongjiang Meteorological Administration, Harbin 150030, China | 2009 | Science China Earth Sciences2009，52，4： | 18 |
| 7 | Quasi-static Analysis of Thrust-loaded Angular Contact Ball Bearings Part Ⅰ:Theoretical Formulation显示文摘Ball bearings play an important role in various rotating machineries,but the complicated kinematic and tribological features of ball bearings make many aspects of their operating behaviors still inconclusive.Most theoretical analyses of ball bearings up to date are based on either the hypothesis of race control or other empirical models to determine the ball motion of ball bearings,but none of these strategies can reveal and consequently employ the intrinsic coupling mechanism between the spin and the tangential traction of contacting bodies rolling upon one another.To remedy the deficiency of current analytical models for ball bearing analysis,the rolling contact theory is employed to establish an explicit link between motions and interactions within ball bearings.A differential slip model is established to precisely define the slip component due to the significant curvature of the common contact patches between the ball and inner/outer raceways.The creepage and the spin ratio are formulated to accurately define the relative rigid motion between the ball and the inner/outer raceway.Then a quasi-static analytical model is established that can accurately determine the motions of the balls and races of the ball bearing.It can also give a vivid description of the slip and traction distributions within the contact area.The analytical model can be effectively used to analyze the operational conditions and tribological features of solid-lubricated ball bearings.It can also be used optimize the construction of ball bearings for specific applications. | CHEN Wenhua1,2,MA Zikui1,GAO Liang1,LI Xinglin3,and PAN Jun2 1 Institute of Mechanical Design,Zhejiang University,Hangzhou 310027,China 2 Institute of Mechanical Design and Manufacturing,Zhejiang Sci-Tech University,Hangzhou 310018,China 3 State Testing Laboratory of Hangzhou Bearing Test & Research Center,Hangzhou 310022,China | 2012 | Chinese Journal of Mechanical Engineering2012，25，1： | 16 |
| 8 | Interactions between hotspots and the Southwest Indian Ridge during the last 90 Ma:Implications on the formation of oceanic plateaus and intra-plate seamounts显示文摘This study investigates the relationship between the hotspot-ridge interaction and the formation of oceanic plateaus and seamounts in the Southwest Indian Ocean.We first calculated the relative distance between the Southwest Indian Ridge (SWIR) and relevant hotspots on the basis of models of plate reconstruction,and then calculated the corresponding excess magmatic anomalies of the hotspots on the basis of residual bathymetry and Airy isostasy.The results reveal that the activities of the Marion hotspot can be divided into three main phases:interaction with the paleo-Rodrigues triple junction (73.6-68.5 Ma),interaction with the SWIR (68.5-42.7 Ma),and intra-plate volcanism (42.7-0 Ma).These three phases correspond to the formation of the eastern,central,and western parts of the Del Cano Rise,respectively.The magnitude and apparent periodicity of the magmatic volume flux of the Marion hotspot appear to be dominated by the hotspot-ridge distance.The periodicity of the Marion hotspot is about 25 Ma,which is much longer than that of the Hawaii and Iceland hotspots (about 15 Ma). | ZHANG Tao 1,2,3,4,LIN Jian 5 & GAO JinYao 3,4 1 Institute of Geodesy and Geophysics,Chinese Academy of Sciences,Wuhan 430077,China 2 Graduate University of Chinese Academy of Sciences,Beijing 100049,China 3 The Second Institute of Oceanography,State Oceanic Administrator,Hangzhou 310012,China 4 Key Laboratory of Submarine Geosciences,State Oceanic Administrator,Hangzhou 310012,China 5 Department of Geology and Geophysics,Woods Hole Oceanographic Institution,Woods Hole,MA 02543,USA | 2011 | Science China Earth Sciences2011，54，8： | 16 |
| 9 | Quantum secret sharing between m-party and n-party with six states显示文摘A quantum secret sharing scheme between an m-party group and an n-party group is proposed using three conjugate bases.A sequence of single photons,each of which is prepared in one of the six states,is used directly to encode classical information in the quantum secret sharing process.In this scheme,each of all m members in group 1 chooses randomly his/her own secret key individually and independently,and directly encodes his/her respective secret information on the states of single photons via unitary operations,then the last one sends 1/n of the resulting qubits to each member of group 2.By measuring their respective qubits,all members in group 2 share the secret information shared by all members in group 1.It renders impossible a Trojan horse attack with a multi-photon signal,a fake-signal attack with EPR pairs,an attack with single photons,and an attack with invisible photons.We give the upper bounds on the average success probabilities for dishonest agent eavesdropping encryption using the fake-signal attack with any two-particle entangled states. | GAO Ting1,YAN FengLi2,3 & LI YouCheng2,3 1 College of Mathematics and Information Science,Hebei Normal University,Shijiazhuang 050016,China 2 College of Physics and Information Engineering,Hebei Normal University,Shijiazhuang 050016,China 3 Hebei Advanced Thin Films Laboratory,Shijiazhuang 050016,China | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，8： | 15 |
| 10 | Soil organic carbon storage and soil CO_2 flux in the alpine meadow ecosystem显示文摘High-resolution sampling,measurements of organic carbon contents and 14C signatures of selected four soil profiles in the Haibei Station situated on the northeast Tibetan Plateau,and application of 14C tracing technology were conducted in an attempt to investigate the turnover times of soil organic car-bon and the soil-CO2 flux in the alpine meadow ecosystem. The results show that the organic carbon stored in the soils varies from 22.12×104 kg C hm-2 to 30.75×104 kg C hm-2 in the alpine meadow eco-systems,with an average of 26.86×104 kg C hm-2. Turnover times of organic carbon pools increase with depth from 45 a to 73 a in the surface soil horizon to hundreds of years or millennia or even longer at the deep soil horizons in the alpine meadow ecosystems. The soil-CO2 flux ranges from 103.24 g C m-2 a-1 to 254.93 gC m-2 a-1,with an average of 191.23 g C m-2 a-1. The CO2 efflux produced from microbial decomposition of organic matter varies from 73.3 g C m-2 a-1 to 181 g C m-2 a-1. More than 30% of total soil organic carbon resides in the active carbon pool and 72.8%―81.23% of total CO2 emitted from or-ganic matter decomposition results from the topsoil horizon (from 0 cm to 10 cm) for the Kobresia meadow. Responding to global warming,the storage,volume of flow and fate of the soil organic carbon in the alpine meadow ecosystem of the Tibetan Plateau will be changed,which needs further research. | TAO Zhen1,2,SHEN ChengDe2,GAO QuanZhou1,SUN YanMin2,YI WeiXi2 & LI YingNian3 1 School of Geography and Planning,Sun Yat-sen University,Guangzhou 510275,China 2 Guangzhou Institute of Geochemistry,Chinese Academy of Sciences,Guangzhou 510640,China 3 Northwest Plateau Institute of Biology,Chinese Academy of Sciences,Xining 810001,China | 2007 | Science China Earth Sciences2007，50，7： | 12 |
| 11 | Primary scientific results of Chang'E-1 lunar mission显示文摘The strategic plan for the development of the unmanned Chinese Lunar Exploration Program is characterized by three distinct stages: 'orbiting around', 'landing on' and 'returning from' the Moon. The first Chinese lunar probe, Chang'E-1, which was successfully launched on October 24th, 2007 at Xichang Satellite Launch Center, and guided to crash on the Moon on March 1st, 2009, at 52.36°E, 1.50°S, in the north of Mare Fecunditatis, is the first step towards the 'orbiting around' stage. The Chang'E-1 mission lasted 495 days, exceeding the expected life-span by about four months. A total of 1.37 TB raw data was received from Chang'E-1. It was then processed into 4 TB scientific data products at various levels. Many scientific results have been obtained by analyzing these data, including especially the 'global lunar image from the first Chinese lunar explora- tion mission'. All scientific goals of Chang'E-1 have been achieved. It provides much useful materials for further advances of lunar sciences and planetary chemistry. Meanwhile, these results will serve as a firm basis for future Chinese lunar missions. | OUYANG ZiYuan1,2, LI ChunLai1, ZOU YongLiao1, ZHANG HongBo1, Lü Chang1, LIU JianZhong1, LIU JianJun1, ZUO Wei1, SU Yan1, WEN WeiBin1, BIAN Wei1, ZHAO BaoChang3, WANG JianYu4, YANG JianFeng3, CHANG Jin5, WANG HuanYu6, ZHANG XiaoHui7, WANG ShiJin7, WANG Min1, REN Xin1, MU LingLi1, KONG DeQing1, WANG XiaoQian1, WANG Fang1, GENG Liang1, ZHANG ZhouBin1, ZHENG Lei1, ZHU XinYing1, ZHENG YongChun1, LI JunDuo1, ZOU XiaoDuan1, XU Chun1, SHI ShuoBiao1, GAO YiFei1 & GAO GuanNan1 1 National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012, China 2 Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550002, China 3 Xi’an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi’an 710119, China 4 Shanghai Institute of Technical Physics, Chinese Academy of Sciences, Shanghai 200083, China 5 Purple Mountain Observatory, Chinese Academy of Sciences, Nanjing 210008, China 6 Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China 7 Center for Space Science and Applied Research, Chinese Academy of Sciences, Beijing 100190, China | 2010 | Science China Earth Sciences2010，53，11： | 11 |
| 12 | Characteristics of pCO_(2) in surface water of the Bering Abyssal Plain and their effects on carbon cycle in the western Arctic Ocean显示文摘Characteristics of the pCO2 distribution in surface water of the Bering Abyssal Plain and their relationships with the ambient hydrological conditions were discussed using variations of the partial pressure of CO2 in surface water of the Bering Abyssal Plain and the Chukchi Sea. Data in this study are from a field investigation during the First Chinese National Arctic Research Expedition in 1999. Compared to the high productivity in the Bering Continental Shelf, much lower levels of chlorophyll a were observed in the Bering Abyssal Plain. The effect of hydrological factors on the pCO2 distribution in surface seawater of the Plain in summer has become a major driving force and dominated over biological factors. The Plain also presents a High Nutrient Low Chlorophyll (HNLC). In addition, the pCO2 distribution in the Bering Abyssal Plain has also been found to be influenced from the Bering Slope Current which would transform to the Anadyr Cur- rent when it inflows northwestward over the Plain. The Anadyr Current would bring a high nutrient water to the western Arctic Ocean where local nutrients are almost depleted in the surface water during the summer time. Resupplying nutrients would stimulate the growth of phytoplankton and enhance capacity of absorbing atmospheric CO2 in the surface water. Otherwise, in the Bering Sea the dissolved inorganic carbon brought from freshwater are not deposited down to the deep sea water but most of them would be transported into the western Arctic Ocean by the Alaska Coastal Current to form a carbon sink there. Therefore, the two carbon sinks in the western Arctic Ocean, one carried by the Anadyr Current and another by the Alaska Costal Current, will impli- cate the western Arctic Ocean in global change. | CHEN Liqi1,2,GAO Zhongyong1,3,WANG Weiqiang3 & YANG Xulin1,3 1.Key Lab of Global Change and Marine-Atmospheric Chemistry,State Oceanic Administration,Xiamen 361005,China 2.Chinese Arctic and Antarctic Administration,Beijing 100860,China 3.Third Institute of Oceanography,State Oceanic Administration,Xiamen 361005,China Correspondence should be addressed to Chen Liqi(email: Lqchen@soa.gov.cn) | 2004 | Science China Earth Sciences2004，47，11： | 11 |
| 13 | Revisiting the origin of modern humans in China and its implications for global human evolution显示文摘The debates over the origin of modern humans have long been centered on two competing theories:the 'Out-of-Africa'(single-place origin) theory and the 'Multi-regional Evolution' theory.China is an extremely important region where many ancient human fossils were collected along with numerous associated faunal remains and artefacts.These cultural remains,unearthed from different areas in the country and covering a long time span,will help clarify the controversy.The study of cultural materials in China is expected to shed important light on biological evolutionary patterns and social and technical developments of those early humans as well as their environmental conditions.Based on the analysis of Chinese fossils and associated materials,in conjunction with some genetic studies,this paper aims at evaluating each of the two theories in order to stimulate more discussions.Our study suggests that the evolutionary model of 'Continuity with Hybridization' is most relevant in reflecting the current understanding of human evolutionary history in China.Furthermore,we propose that the concept of regional diversity of evolutionary models should be seriously considered to illustrate different evolutionary modes applied to different parts of the world. | GAO Xing1,2*,ZHANG XiaoLing1,2,3,YANG DongYa2,4,SHEN Chen2,5 & WU XinZhi1,2 1 Institute of Vertebrate Paleontology and Paleoanthropology,Chinese Academy of Sciences,Beijing 100044,China 2 Laboratory of Human Evolution,Chinese Academy of Sciences,Beijing 100044,China 3 Graduate University of Chinese Academy of Sciences,Beijing 100049,China 4 Department of Archaeology,Simon Fraser University,Vancouver V5A 1S6,Canada 5 The Royal Ontario Museum,Toronto M5S 2C6,Canada | 2010 | Science China Earth Sciences2010，53，12： | 11 |
| 14 | Study on interaction between microtubule associated protein tau and prion protein显示文摘Microtubule-associated protein tau is considered to play roles in many neurodegenera-tive diseases including some transmissible spongiform encephalopathies.To address the possible molecular linkage of prion protein(PrP) and tau,a GST-fusion segment of human tau covering the three-repeat region and various PrP segments was used in the tests of GST pull-down and immuno-precipitation.We found tau protein interacted with various style prion proteins such as native prion protein(PrPC) or protease-resistant isoform(PrPSc) .Co-localization signals of tau and PrP were found in the CHO cell tranfected with both PrP and tau gene.The domain of interaction with tau was located at N-terminal of PrP(residues 23 to 91) .The evidence of molecular interactions between PrP and tau protein highlights a potential role of tau in the biological function of PrP and the pathogenesis of TSEs. | HAN Jun1,ZHANG Jin1,2,YAO Hailan1,3,WANG Xiaofan1,LI Feng1,CHEN Lan1,4,GAO Chen1,GAO Jianmei1,NIE Kai1,ZHOU Wei1 & DONG Xiaoping11.State Key Laboratory for Infectious Diseases Prevention and Control,National Institute for Viral Disease Control and Pre-vention,Chinese Center for Disease Control and Prevention,Beijing 100052,China 2.School of Medicine,Xi’an Jiao-Tong University,Xi’an 710061,China 3.Tong-Ji Medical College,Hua-Zhong University of Science and Technology,Wuhan 430030,China 4.National Laboratory of Medical Molecular Biology,Institute of Basic Medical Science,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100005,China | 2006 | Science China(Life Sciences)2006，49，5： | 10 |
| 15 | HJ-1A HSI on-orbit radiometric calibration and validation research显示文摘The calibration experiment data at Dunhuang radiometric calibration site in October, 2008 were used to achieve the on-orbit radiometric calibration for HJ-1A hyper spectral imager (HSI). Two other field experiments data were used to validate the Dunhuang calibration results. One field experiment took place in Inner-Mongolia, China in September, 2008, and the other field experiment took place in Lake Frome, Australia in February, 2009. Finally, the ‘confidence interval of calibration error’ concept was put forward for quantitatively computing the calibration coefficient error confidence interval. The results showed that the Dunhuang calibration results in 2008 had high reliability. The confidence intervals of calibration error for all HSI channels were between 2% to 12%, which could satisfy the requirement of the HSI quantitative applications. | GAO HaiLiang1,2,3*, GU XingFa1,3*, YU Tao1,3, GONG Hui1,2,3, LI JiaGuo1,2,3 & LI XiaoYing1,3 1 State Key Laboratory of Remote Sensing Science, Jointly Sponsored by the Institute of Remote Sensing Applications of Chinese Academy of Sciences and Beijing Normal University, Beijing 100101, China 2 Graduate University of Chinese Academy of Sciences, Beijing 100039, China 3 Center for National Spaceborne Demonstration, Beijing 100101, China | 2010 | Science China(Technological Sciences)2010，53，11： | 10 |
| 16 | Recombinant expression of rt-PA gene (encoding Reteplase) in gametophytes of the seaweed Laminaria japonica (Laminariales,Phaeophyta)显示文摘The life cycle of seaweed Laminaria japonica involves a generation alternation between diploid sporophyte and haploid gametophte. The expression of foreign genes in sporophte has been proved. In this research, the recombinant expression in gametophyte was investigated by particle bombardment with the rt-PA gene encoding the recombinant human tissue-type plasminogen activator (Reteplase), which is a thrombolytic agent for acute myocardial infarction (AMI). Transgenic gametophytes were selected by their resistance to herbicide phosphiothricin (PPT), and proliferated in an established bubble column photo-bioreactor. According to the results from quantitative ELISA, Southern blotting, and fibrin agarose plate assay (FAPA) for bioactivity, it was showed that the rt-PA gene had been inte-grated into the genome of gametophytes of L. japonica, and the expression product showed the ex-pected bioactivity, implying the proper post-transcript modification in haploid gametophyte. | ZHANG YiChen1,2, JIANG Peng1, GAO JiangTao1,3, LIAO JianMin4, SUN ShiJing4, SHEN ZiLong4 & QIN Song1, 1 Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China 2 College of Chemistry and Life Science, Tianjin Normal University, Tianjin 300387, China 3 Graduate University of Chinese Academy of Sciences, Beijing 100049, China 4 Biotechnology Center, China Pharmaceutical University, Nanjing 210009, China | 2008 | Science China(Life Sciences)2008，51，12： | 9 |
| 17 | Optimal controlled teleportation via several kinds of three-qubit states显示文摘The probability of successful controlled teleportation of an unknown qubit using a general three-particle state is investigated. The analytic expressions of maximal probabilities via several kinds of tripartite states are given, including a tripartite Greenberger-Horne-Zeilinger state and a tripartite W-state. | GAO Ting1,2, YAN FengLi2,3 & LI YouCheng3 1 College of Mathematics and Information Science, Hebei Normal University, Shijiazhuang 050016, China 2 Max-Planck-Institut für Quantenoptik, Hans-Kopfermann-Str. 1, D-85748 Garching, Germany 3 College of Physics and Information Engineering, Hebei Normal University, Shijiazhuang 050016, China | 2008 | Science China(Physics,Mechanics & Astronomy)2008，51，10： | 9 |
| 18 | Approximate homotopy symmetry method:Homotopy series solutions to the sixth-order Boussinesq equation显示文摘An approximate homotopy symmetry method for nonlinear problems is proposed and applied to the sixth-order Boussinesq equation,which arises from fluid dynamics.We summarize the general formulas for similarity reduction solutions and similarity reduction equations of different orders,educing the related homotopy series solutions.Zero-order similarity reduction equations are equivalent to the Painlevé IV type equation or Weierstrass elliptic equation.Higher order similarity solutions can be obtained by solving linear variable coefficients ordinary differential equations.The auxiliary parameter has an effect on the convergence of homotopy series solutions.Series solutions and similarity reduction equations from the approximate symmetry method can be retrieved from the approximate homotopy symmetry method. | JIAO XiaoYu1,GAO Yuan1 & LOU SenYue1,2,3 1 Department of Physics,Shanghai Jiao Tong University,Shanghai 200240,China 2 Department of Physics,Ningbo University,Ningbo 315211,China 3 School of Mathematics,Fudan University,Shanghai 200433,China | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，8： | 8 |
| 19 | Geochemistry of ophiolite cherts from the Qinling orogenic belt and implications for their tectonic settings显示文摘Paleozoic cherts from the Mianl黣 and the Erlangping ophiolite zones of the Qinling orogenic belt are characterized by low Si/Al ratios (52.14-683.52 in the Mianle cherts, 12.29-58.62 in the Erlangping cherts), Fe2O3 (0.01-0.35 and 0.02-1.24) and high Al2O3/(Al2O3+Fe2O3) ratios (0.82-0.99 and 0.83-0.99). The negative correlation between Si2O and Al2O3 in the cherts reflects the important role of terrigenous components. The Erlangping cherts have Lan/Cen=0.9-1.15 and Ce/Ce*=0.95-1.15 with low contents of V, Ni and Cu, consistent with those of cherts forming on the continental margin. In contrast, the Ce/Ce* ratios of the Mianle cherts range from 0.71 to 1.18 and Lan/Cen from 0.88 to 1.43 with slightly high V, Ni and Cu, which are similar to cherts found in the mid-ocean ridges and pelagic basins. Combined with the features of basic lavas associated with the cherts, it is suggested that during the Paleozoic, when the back-arc basin represented by the Erlangping ophiolite commenced shrinking in size in the mid-Ordovician, the southern Qinling was still in an extensional regime and finally grew into a new limited oceanic basin in the early Carboniferous. | ZHANG Chengli1, 2, GAO Shan1, 3, ZHANG Guowei1, GUO Anlin1, YUAN Honglin1, LIU Xiaoming1 & WANG Jianqi1 1. The key Laboratory of Continental Dynamics, Ministry of Education, Department of Geology, Northwest University, Xian 710069China 2. State Key Laboratory for Mineral Deposits Research, Nanjing University, Nanjing 210093, China 3. Department of Geochemistry, China University of Geosciences, Wuhan 430074, China | 2004 | Science China Earth Sciences2004，47，4： | 8 |
| 20 | Arabian Peninsula-North Pacific Oscillation and its association with the Asian summer monsoon显示文摘Using correlation and EOF analyses on sea level pressure from 57-year NCEP-NCAR reanalysis data, the Arabian Peninsula-North Pacific Oscillation (APNPO) is identified. The APNPO reflects the co-variability between the North Pacific high and South Asian summer monsoon low. This teleconnec- tion pattern is closely related to the Asian summer monsoon. On interannual timescale, it co-varies with both the East Asian summer monsoon (EASM) and South Asian summer monsoon (SASM); on decadal timescale, it co-varies with the EASM: both exhibit two abrupt climate changes in the middle 1960s and the late 1970s respectively. The possible physical process for the connections between the APNPO and Asian summer monsoon is then explored by analyzing the APNPO-related atmospheric circulations. The results show that with a strong APNPO, the Somali Jet, SASM flow, EASM flow, and South Asian high are all enhanced, and an anomalous anticyclone is produced at the upper level over northeast China via a zonal wave train. Meanwhile, the moisture transportation to the Asian monsoon regions is also strengthened in a strong APNPO year, leading to a strong moisture convergence over India and northern China. All these changes of circulations and moisture conditions finally result in an anoma- lous Asian summer monsoon and monsoon rainfall over India and northern China. In addition, the APNPO has a good persistence from spring to summer. The spring APNPO is also significantly corre- lated with Asian summer monsoon variability. The spring APNPO might therefore provide valuable in- formation for the prediction of Asian summer monsoon. | SUN JianQi1, YUAN Wei2 & GAO YuZhong3 1 Nansen-Zhu International Research Centre, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100029, China 2 China Meteorological Administration Training Centre, Beijing 100081, China 3 Heilongjiang Meteorological Observatory, Harbin 150030, China | 2008 | Science China Earth Sciences2008，51，7： | 8 |
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