|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Clinical application of concentrated bone marrow aspirate in orthopaedics:A systematic review显示文摘AIM To examine the evidence behind the use of concentrated bone marrow aspirate(c BMA) in cartilage, bone, and tendon repair; establish proof of concept for the use of cB MA in these biologic environments; and provide the level and quality of evidence substantiating the use of cB MA in the clinical setting.METHODS We conducted a systematic review according to PRISMA guidelines. EMBASE, MEDLINE, and Web of Knowledge databases were screened for the use of cB MA in the repair of cartilage, bone, and tendon repair. We extracted data on tissue type, cB MA preparation, cB MA concentration, study methods, outcomes, and level of evidence and reported the results in tables and text.RESULTS A total of 36 studies met inclusion/exclusion criteria and were included in this review. Thirty-one of 36(86%) studies reported the method of centrifugation and preparation of cB MA with 15(42%) studies reporting either a cell concentration or an increase from baseline. Variation of c BMA application was seen amongst the studies evaluated. Twenty-one of 36(58%) were level of evidence Ⅳ, 12/36(33%) were level of evidence Ⅲ, and 3/36(8%) were level of evidence Ⅱ. Studies evaluated full thickness chondral lesions(7 studies), osteochondral lesions(10 studies), osteoarthritis(5 studies), nonunion or fracture(9 studies), or tendon injuries(5 studies). Significant clinical improvement with the presence of hyaline-like values and lower incidence of fibrocartilage on T2 mapping was found in patients receiving cB MA in the treatment of cartilaginous lesions. Bone consolidation and time to bone union was improved in patients receiving cB MA. Enhanced healingrates, improved quality of the repair surface on ultrasound and magnetic resonance imaging, and a decreased risk of re-rupture was demonstrated in patients receiving cB MA as an adjunctive treatment in tendon repair. CONCLUSION The current literature demonstrates the potential benefits of utilizing c BMA for the repair of cartilaginous lesions, bony defects, and tendon injuries in the clinical setting. This study also demonstrates discrepancies between the literature with regards to various methods of centrifugation, variable cell count concentrations, and lack of standardized outcome measures. Future studies should attempt to examine the integral factors necessary for tissue regeneration and renewal including stem cells, growth factors and a biologic scaffold. | Arianna L Gianakos Li Sun Jay N Patel Donald M Adams Frank A Liporace | 2017 | World Journal of Orthopedics2017，8，6： | 5 |
| 2 | Diagnostic accuracy of tests for Helicobacter pylori in an Alaska Native population显示文摘AIM:To evaluate the accuracy of two non-invasivetests in a population of Alaska Native persons. Highrates of Helico bacter pylori(H. pylori) infection,H. pylori treatment failure,and gastric cancer in this population necessitate documentation of infection status atmultiple time points over a patient's life.METHODS:In 280 patients undergoing endoscopy,H. pylori was diagnosed by culture,histology,rapidurease test,13C urea breath test(UBT) ,and immuno-globulin G antibodies to H. pylori in serum. The performances of 13C-UBT and antibody test were compared to a gold standard defined by a positive H. pylori testby culture or,in case of a negative culture result,bypositive histology and a positive rapid urease test.RESULTS:The sensitivity and specificity of the 13C-UBT were 93% and 88%,respectively,relative to thegold standard. The antibody test had an equivalents ensitivity of 93% with a reduced specificity of 68%.The false positive results for the antibody test were as-sociated with previous treatment for an H. pylori infection [relative risk(RR) = 2.8]. High levels of antibodiesto H. pylori were associated with chronic gastritis and male gender,while high scores in the 13C-UBT testwere associated with older age and with the H. pyloribacteria load on histological examination(RR = 4.4) .CONCLUSION:The 13C-UBT out performed the anti-body test for H. pylori and could be used when a non-invasive test is clinically necessary to document treatment out come or when monitoring for reinfection. | Dana L Bruden Michael G Bruce Karen M Miernyk Julie Morris Debby Hurlburt Thomas W Hennessy Helen Peters Frank Sacco Alan J Parkinson Brian J McMahon | 2011 | World Journal of Gastroenterology2011，17，42： | 3 |
| 3 | Human enamel thickness and ENAM polymorphism显示文摘The tooth enamel development gene, enamelin(ENAM), showed evidence of positive selection during a genome-wide scan of human and primate DNA for signs of adaptive evolution. The current study examined the hypothesis that a single-nucleotide polymorphism(SNP) C14625T(rs7671281) in the ENAM gene identified in the genome-wide scan is associated with a change in enamel phenotype. African Americans were selected as the target population, as they have been reported to have a target SNP frequency of approximately 50%, whereas non-Africans are predicted to have a 96% SNP frequency. Digital radiographs and DNA samples from 244 teeth in 133 subjects were analysed, and enamel thickness was assessed in relation to SNP status,controlling for age, sex, tooth number and crown length. Crown length was found to increase with molar number, and females were found to have thicker enamel. Teeth with larger crowns also had thicker enamel, and older subjects had thinner enamel.Linear regression and generalized estimating equations were used to investigate the relationship between enamel thickness of the mandibular molars and ENAM SNP status; enamel in subjects with the derived allele was significantly thinner(P = 0.040)when the results were controlled for sex, age, tooth number and crown length. The derived allele demonstrated a recessive effect on the phenotype. The data indicate that thinner dental enamel is associated with the derived ENAM genotype. This is the first direct evidence of a dental gene implicated in human adaptive evolution as having a phenotypic effect on an oral structure. | Diane M Daubert Joanna L Kelley Yuriy G Udod Carolina Habor Chris G Kleist Ilona K Furman Igor N Tikonov Willie J Swanson Frank A Roberts | 2016 | International Journal of Oral Science2016，8，2： | 2 |
| 4 | Qualitative and quantitative analysis of a thermoset polymer, poly(benzoxamine), by pyrolysis - gas chromatography 显示文摘 | Frank Cheng - Yu Wang Dettloff M L Null M J | 2000 | Journal of ChromatographyA2000，886，12： | 1 |
| 5 | A one-year survey of halogenated disinfection by-products in the distribution system of treatment plants using three different disinfection processes显示文摘 | Guy L Label Frank M | 1997 | Chemosphere1997，24，11： | 1 |
| 6 | Urban form, travel time, and cost relationships with tour complexity and mode choice显示文摘 | Frank L Bradley M Kavage S | 2008 | Transportation2008，35，1： | 1 |
| 7 | Absorption of a mixture of volatile organic compounds(VOCs) in aqueous solutions of soluble cutting oil显示文摘 | FRANK L LUC M JEAN-CLAUDE R | 2008 | Bioresource Technology2008，99，6： | 1 |
| 8 | Brain-derived neurotro- phic factor regulates hedonic feeding by acting on the mesolimbic dopamine system显示文摘 | Cordeira J Frank L Sena-Esteves M | 2010 | J Neurosci2010，30，7： | 1 |
| 9 | Upstream hydromagnetic-waves and their association with back-streaming ion populations-Isee-1 and 2 observations显示文摘 | Hoppe M M Russell C T Frank L A | | 0，，06： | 1 |
| 10 | Termination of hull-imposed dormancy in developing barley grains is correlated with changes in embryonic ABA levels and sensitivity显示文摘 | Benech-Arnold R L M Giallorenzi C Frank J | 1999 | Seed SciRes1999，9，4： | 1 |
| 11 | Sensitivity of isolates of Sclerotium rolfsii from peanut in Georgia to Selected Fungicides显示文摘 | Franke M D Brenneman T B Stevenson K L | 1998 | Plant Disease1998，82，： | 1 |
| 12 | Retroreflection reduction by masking apertures 显示文摘 | Arjan L Mieremet Ric M A Schleijpen Frank J M van Putten | 2010 | Optical Engineering2010，49，4： | 1 |
| 13 | Red tide detection and tracing using MODIS fluorescence data: a regional example in SW Florida coastal waters显示文摘 | Hu C M MULLER K FRANK E TAYLOR C CARDER K L JOHNS E HEIL C A | 2005 | Remote Sensing of Environment2005，97，3： | 1 |
| 14 | Current tissue engineering strategies in anterior cruciate ligament reconstruction 显示文摘 | LEONG N L FRANK F A DAVID R M | 2014 | Journal of Biomedical Materials Research : Part A2014，102，5： | 1 |
| 15 | Nonlinear observer design via an extended observer canonical form 显示文摘 | Ding X C Frank P M Guo L M | 1990 | Systems & Control Letters1990，15，4： | 1 |
| 16 | Comparative toxicity of copper and acridine to fish,daphnia and alage显示文摘 | BLAYLICK B G FRANK M L MCCARTJY J M | 1985 | Environmental Toxicology and Chemistry1985，4，1： | 1 |
| 17 | Disinfection by-products in canadian drinking water显示文摘 | David T Williams Guy L LeBel Frank M Benoit | 1997 | Chemosphere1997，34，2： | 1 |
| 18 | Atmospheric Correction of SeaWiFS Imagery over Turbid Coastal Waters:a Practical Method显示文摘 | Chuanmin H Kendall L C Frank E M K | 2000 | Remo Sens Env2000，74，： | 1 |
| 19 | Nogo-A is a myelin-associated neurite out-growth inhibitor and an antigen for monoclonal antibody IN-1 显示文摘 | Chen MS Huber AB van der Haar ME Frank M Schnell L Spillmann AA | 2000 | Nature2000，403，6768： | 1 |
| 20 | A Recon-figurable Direct RF Receiver With Jitter Analysis andApplications 显示文摘 | FUDGE G L HAMID M A FRANK A B | 2013 | IEEE Trans on Circuits and Sys-tems2013，60，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员