|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Near-infrared fluorescence sentinel lymph node detection in gastric cancer: A pilot study显示文摘AIM: To investigate feasibility and accuracy of nearinfrared fluorescence imaging using indocyanine green: nanocolloid for sentinel lymph node(SLN) detection in gastric cancer.METHODS: A prospective, single-institution, phaseI feasibility trial was conducted. Patients suffering from gastric cancer and planned for gastrectomy were included. During surgery, a subserosal injection of 1.6 m L ICG:Nanocoll was administered around the tumor. NIR fluorescence imaging of the abdominal cavity was performed using the Mini-FLARE? NIR fluorescence imaging system. Lymphatic pathways and SLNs were visualized. Of every detected SLN, the corresponding lymph node station, signal-to-background ratio and histopathological diagnosis was determined. Patients underwent standard-of-care gastrectomy. Detected SLNs outside the standard dissection planes were also resected and evaluated.RESULTS: Twenty-six patients were enrolled. Four patients were excluded because distant metastases were found during surgery or due to technical failure of the injection. In 21 of the remaining 22 patients, at least 1 SLN was detected by NIR Fluorescence imaging(mean 3.1 SLNs; range 1-6). In 8 of the 21 patients, tumor-positive LNs were found. Overall accuracy of the technique was 90%(70%-99%; 95%CI), which decreased by higher p T-stage(100%, 100%, 100%, 90%, 0% for respectively Tx, T1, T2, T3, T4 tumors). All NIR-negative SLNs were completely effaced by tumor. Mean fluorescence signal-to-background ratio of SLNs was 4.4(range 1.4-19.8). In 8 of the 21 patients, SLNs outside the standard resection plane were identified, that contained malignant cells in 2 patients.CONCLUSION: This study shows successful use of ICG:Nanocoll as lymphatic tracer for SLN detection in gastric cancer. Moreover, tumor-containing LNs outside the standard dissection planes were identified. | Quirijn RJG Tummers Leonora SF Boogerd Wobbe O de Steur Floris PR Verbeek Martin C Boonstra Henricus JM Handgraaf John V Frangioni Cornelis JH van de Velde Henk H Hartgrink Alexander L Vahrmeijer | 2016 | World Journal of Gastroenterology2016，22，13： | 9 |
| 2 | Relationship be tween skin color and sun exposure history: a statistical classi- fication approach显示文摘 | RUBEGNI P CEENINI G FLORI M L | 1997 | Photoehem Photobiol1997，65，2： | 1 |
| 3 | 显示文摘 | JERMIGAN R L Flory P J | 1969 | J Chem Phys1969，50，： | 1 |
| 4 | Reproducibility of endometrial vascular patterns in endometrial disease as assessed by transvaginal power Doppler sonography in women with postmenopausal bleeding显示文摘 | Alcazar J L Ajossa S Floris S | 2006 | J Ultrasound Med2006，25，2： | 1 |
| 5 | The GPI-anchored CD52 antigen of the sperm surface interacts with semenogelin and participates in clot formation and liquefaction of human semen显示文摘 | Ermini L La Sala GB | 2008 | Mol Repred Dev2008，75，2： | 1 |
| 6 | Non-native grass invasion alters native plant composi- tion in experimental communities显示文摘 | Flory S L Clay K | 2010 | Biological Invasions2010，12，5： | 1 |
| 7 | Alpha-glucosidase inhibitors in the early treatment of type 2 diabetes显示文摘 | Floris A L | 2008 | Vasc Health Risk Manag2008，4，6： | 1 |
| 8 | Advances in 3-D forging process modeling显示文摘 | Slagter W J Florie C J L Venis A C J | 1991 | Journal of Computational Physics1991，92，1： | 1 |
| 9 | The genome response to artificial selection: a case study in dairy cattle显示文摘 | Flori L Fritz S Jaffr6zic F | 2009 | PLoS One2009，4，8： | 1 |
| 10 | HLA-haplotypes and class Ⅱ molecular alleles in Sardinian and Italian patients with pemphigus vulgaris显示文摘 | Carcassi C Cottoni F Floris L | | 0，，： | 1 |
| 11 | Extended transsphenoidal microsurgical approach for diaphragma sellae and tuberculum meningiomas显示文摘 | Fraioli MF Moschettoni L Floris R | 2009 | Minim Invasive Neurosurg2009，52，56： | 1 |
| 12 | Up-regulation of MET expression by alpha-melanocyte-stimulating hormone and MITF allows hepatocyte growth factor to protect melanocytes and melanoma cells from apoptosis显示文摘 | Beuret L Flori E Denoyelle C | 2007 | J Biol Chem2007，282，14： | 1 |
| 13 | Linkage and association between plasmodium falciparum blood infeetion levels and chro- mosome 5q31-q33显示文摘 | Flori L Kumulungui B Aucan C | 2003 | Genes Immun2003，4，： | 1 |
| 14 | Practical applications of cutaneous colorimetry显示文摘 | Flori L | 1995 | Clin Dermatol1995，13，4： | 1 |
| 15 | Differential effects of nitrogenous fertilizers on methane-consuming microbes in rice field and forest soils显示文摘 | Mohanty S R Bodelier P L Floris V | 2006 | Applied and Environmental Microbiology2006，72，2： | 1 |
| 16 | Comparison of stability in theoperative treatment of pelvic injuries in a finite elementmodel显示文摘 | Bodzay T Floris l Varadi K | 2011 | Arch Orthop Trauma Surg2011，131，10： | 1 |
| 17 | Extended transsphenoidal microsurgical approach for diaphragma sellae and tuberculum meningiomas 显示文摘 | Fraioli MF Moschettoni L Floris R | 2009 | Minim lnvasive Neurosurg2009，52，56： | 1 |
| 18 | Differential effects of nitrogenous fertilizers on methane-consuming microbes in rice field and forest soils 显示文摘 | Mohanty S R Bodelier L E Floris V | 2006 | Appl Environ Microbiol2006，72，： | 1 |
| 19 | The genome response to artificial selection:A case study in dairy cattle显示文摘 | Flori L Fritz S Jaffrezic F | 2009 | PLoS One2009，4，8： | 1 |
| 20 | Near‐infrared fluorescence‐guided resection of colorectal liver metastases显示文摘 | Joost R. van der Vorst Boudewijn E. Schaafsma Merlijn Hutteman Floris P. R. Verbeek Gerrit‐Jan Liefers Henk H. Hartgrink Vincent T. H. B. M. Smit Clemens W. G. M. L?wik Cornelis J. H. van de Velde John V. Frangioni Alexander L. Vahrmeijer | 2013 | Cancer2013，，18： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员