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| 1 | Gastric cancer:Prevention,screening and early diagnosis显示文摘Gastric cancer continues to be an important healthcare problem from a global perspective. Most of the cases in the Western world are diagnosed at late stages when the treatment is largely ineffective. Helicobacter pylori(H. pylori) infection is a well-established carcinogen for gastric cancer. While lifestyle factors are important,the efficacy of interventions in their modification,as in the use of antioxidant supplements,is unconvincing. No organized screening programs can be found outside Asia(Japan and South Korea). Although several screening approaches have been proposed,including indirect atrophy detection by measuring pepsinogen in the circulation,none of them have so far been implemented,and more study data is required to justify any implementation. Mass eradication of H. pylori in high-risk areas tends to be cost-effective,but its adverse effects and resistance remain a concern. Searches for new screening biomarkers,including microRNA and cancer-autoantibody panels,as well as detection of volatile organic compounds in the breath,are in progress. Endoscopy with a proper biopsy follow-up remains the standard for early detection of cancer and related premalignant lesions. At the same time,new advanced high-resolution endoscopic technologies are showing promising results with respect to diagnosing mucosal lesions visually and targeting each biopsy. New histological risk stratifications(classifications),including OLGA and OLGIM,have recently been developed. This review addresses the current means for gastric cancer primary and secondary prevention,the available and emerging methods for screening,and new developments in endoscopic detection of early lesions of the stomach. | Victor Pasechnikov Sergej Chukov Evgeny Fedorov Ilze Kikuste Marcis Leja | 2014 | World Journal of Gastroenterology2014，20，38： | 64 |
| 2 | Characteristics of the active-layer under the China-Russia Crude Oil pipeline显示文摘Active layer is a key component for permafrost environment studies as many subsurface biological,biogeochemical,ecological,and pedogenic activities prevail in this layer.This study focuses on active layer temperature monitoring in an area with sporadic permafrost at two adjacent sites along China-Russia Crude Oil Pipeline(CRCOP),NorthEast China.Site T1 is located in disturbed ground on the right-of-way(on-ROW)2 m away from the center of the oil pipeline.T2 is located in a natural and undisturbed site,around 16.6 m off-ROW.Our objective was to study seasonal variability of the active layer depth and thermal regime from October 2017 to September 2018.The monitoring sites consist of soil temperature probes arranged in a vertical array at different depths at both sites.The following parameters were computed:number of isothermal days(ID),freezing days(FD),thawing days(TD),freezing degree days(FDD),thawing degree days(TDD),number of freeze-thaw days(FTD).The mean air temperature in the monitoring period reached-3.2℃.The temperature profile indicates that the maximum active layer thickness observed during the study period was 10 m at T1 and 2 m at T2.The majority of the soil temperatures were above or close to 0℃,resulting in great values of TDD,especially in the first 4 m depth.TDD for T1 were predominant and ranged between 600-1160℃·days(0-4 m depth)reflecting the influence of oil temperature from the pipeline.In T2 borehole FDD were predominant for all the soil layer depths resulting in less permafrost degradation.This comparison emphasizes the significant influence of vegetation removal and the dispersed heat from the pipeline on the active layer thickness. | SERBAN Mihaela LI Guo-yu SERBAN Raul-David WANG Fei FEDOROV Alexander VERA Samsonova CAO Ya-peng CHEN Peng-chao WANG Wei | 2021 | Journal of Mountain Science2021，18，2： | 4 |
| 3 | Robust general N User authentication scheme in a centralized quantum communication network via generalized G HZ states显示文摘 | Ahmed Farouk J. Batle M. Elhoseny Mosayeb Naseri Muzaffar Lone Alex Fedorov Majid Alkhambashi Syed Hassan Ahmed M. Abdel-Aty | 2018 | Frontiers of physics2018，13，2： | 3 |
| 4 | Lead Tungstate Scintillation Crystal with Increased Light Yield for the PANDA Electromagnetic Calorimeter显示文摘 | Borisevich A Fedorov A Hofstaetter A | 2005 | Nuclear Instruments and Methods in Physics Research A2005，537，12： | 1 |
| 5 | The Kinetic of Coating Formation in Microarc Oxidation Process 显示文摘 | Bulyshev S I Fedorov V A | 1993 | J Fiz Khim Obrob Mater1993，17，6： | 1 |
| 6 | Benzodi- azepines and benzotriazepines as protein interaction inhibi- tots targeting bromodomains of the BET family显示文摘 | Filippakopoulos P Picaud S Fedorov O | 2012 | Bioorg Med Chem2012，20，6： | 1 |
| 7 | Mathematical modeling of methane flow in coal beds显示文摘 | A. V. Fedorov I. A. Fedorchenko | 2009 | Journal of Mining Science2009，，1： | 1 |
| 8 | 查看详情显示文摘 | Baur M Fedorov A Steffen L Filipp S Silva M P Wallraff A | | 0，，： | 1 |
| 9 | Liquid missile propellants in the former Soviet Union显示文摘 | Fedorov L A | | 0，，02： | 1 |
| 10 | Anticaneer and Cancer Preventive Properties of Marine Polysaccharides: Some Results and Prospects显示文摘 | Sergey N Fedorov Svetlana P Ermakova Tatyana N Zvyagintseva | 2013 | Mar Drugs Dee2013，11，12： | 1 |
| 11 | The flora of southwestern China and its significance to the knowledge of the plant world of Eurasia显示文摘 | Fedorov An A | 1957 | Komarov Chten1957，10，： | 1 |
| 12 | Characterisation of bacterially expressed structural protein E2 of hepatitis C virus显示文摘 | Yurkova M S Patel A H Fedorov A N | 2004 | Protein Expression and Purification2004，37，1： | 1 |
| 13 | Robotic-assisted abdominal surgery显示文摘 | Fedorov AV Kriger AG Berelavichus SV | 2010 | Khirurgiia (Mosk)2010，，1： | 1 |
| 14 | Special features of the microstructrue of hardened surface layers produced by microarc oxidation显示文摘 | Alekhin V P Fedorov V A Bulychev S I | 1991 | Phys Chem Mater Treat1991，25，5： | 1 |
| 15 | Three-Dimensional Conjugate Heat Transfer in the Microchannel Heat Sink for Electronic Packaging显示文摘 | Fedorov A G Viskanta R | 2000 | Int J Heat Mass Transfer2000，43，3： | 1 |
| 16 | IiNbOa optical waveguide fabrication by high-temperature proton- exchange显示文摘 | KORKISHKO Y N FEDOROV V A FEOKTISTOVA O Y | 2000 | Lightwave Technol2000，18，： | 1 |
| 17 | Climate impacts of intermittent upper ocean mixing induced by tropical cyclones 显示文摘 | Manueharyan G E Brierley C M Fedorov A V | 2011 | J Geophys Res2011，，10： | 1 |
| 18 | Highly effective Mgz Si1-x Sn x thermoelectrics 显示文摘 | Zaitsev V K Fedorov M I Gurieva E A | 2006 | Phys Review B2006，74，04： | 1 |
| 19 | GBM volumetry using the 3D slicer medical image computing platform显示文摘 | Egger J Kapur T Fedorov A | 2013 | Scientific Reports2013，3，3： | 1 |
| 20 | Roles of adrenergic and cholinergic stimulation in spontaneous atrial fibrillation in dogs显示文摘 | Sharifov OF Fedorov VV Beloshapko GG | 2004 | J Am Coll Cardiol2004，43，： | 1 |
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