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| 1 | 非典型性脂肪瘤性肿瘤及各种变型和复合形式显示文摘 | Evans H L 刘飞飞(摘译) 张仁亚(审校) | 2007 | 临床与实验病理学杂志2007,23,1: | 15 |
| 2 | Carotid Intima-media Thickness Measurements: Relations with Atherosclerosis, Risk of Cardiovascular Disease and Application in Randomized Controlled Trials显示文摘INTRODUCTION Cardiovascular disease (CVD) is the leading cause of death worldwide and contributes considerably to morbidity[1-3] The underlying cause is atherosclerosis.[4] The development of new preventive therapies is one of the steps to control the CVD epidemic.It is increasingly demanded that promising therapies be evaluated in trials using cardiovascular (CV) morbidity and mortality (M and M) as a primary outcome.[5] | Michiel L Bots Gregory W Evans Charles H Tegeler Rudy Meijer | 2016 | Chinese Medical Journal2016,,2: | 15 |
| 3 | Colonic ulcerations may predict steroid-refractory course in patients with ipilimumab-mediated enterocolitis显示文摘AIM To investigate management of patients who develop ipilimumab-mediated enterocolitis, including association of endoscopic findings with steroid-refractory symptoms and utility of infliximab as second-line therapy.METHODS We retrospectively reviewed all patients at our centerwith metastatic melanoma who were treated with ipilimumab between March 2011 and May 2014. All patients received a standard regimen of intravenous ipilimumab 3 mg/kg every 3 wk for four doses or until therapy was stopped due to toxicity or disease progression. Basic demographic and clinical data were collected on all patients. For patients who developed grade 2 or worse diarrhea(increase of 4 bowel movements per day), additional data were collected regarding details of gastrointestinal symptoms, endoscopic findings and treatment course. Descriptive statistics were used.RESULTS A total of 114 patients were treated with ipilimumab during the study period and all were included. Sixteen patients(14%) developed ≥ grade 2 diarrhea. All patients were treated with high-dose corticosteroids(1-2 mg/kg prednisone daily or equivalent). Nine of 16 patients(56%) had ongoing diarrhea despite highdose steroids. Steroid-refractory patients received one dose of intravenous infliximab at 5 mg/kg, and all but one had brisk resolution of diarrhea. Fourteen of the patients underwent either colonoscopy or sigmoidoscopy with variable endoscopic findings, ranging from mild erythema to colonic ulcers. Among 8 patients with ulcers demonstrated by sigmoidoscopy or colonoscopy, 7 patients(88%) developed steroidrefractory symptoms requiring infliximab. With a median follow-up of 264 d, no major adverse events associated with prednisone or infliximab were reported.CONCLUSION In patients with ipilimumab-mediated enterocolitis, the presence of colonic ulcers on endoscopy was associated with a steroid-refractory course. | Animesh Jain Evan J Lipson William H Sharfman Steven R Brant Mark G Lazarev | 2017 | World Journal of Gastroenterology2017,23,11: | 8 |
| 4 | Acute liver failure due to natural killer-like T-cell leukemia/ lymphoma: A case report and review of the Literature显示文摘尖锐的肝失败(ALF ) 是为肝移植要求立即的评估的一种医药紧急情况。我们描述与腹水,黄疸,和脑病介绍了并且被发现由于象 T 房间白血病 / 淋巴瘤一样的生来的杀手(NK ) 有 ALF 的一个病人的一个不平常的盒子。关键免疫显型是 CD2+ , CD3+ , CD7+ , CD56+ 。这诊断,在外部血和腹水基于调查结果,与肝活体检视被证实,并且是到肝移植的禁止徵候。hematologic 恶意是暴发性的肝的失败的一个不平常的原因的文学表演的评论,和那个象 NK 一样 T 房间白血病 / 淋巴瘤是一最近相对表示特性地认出了是的实体 CD3+ 和 CD56+ 。这个盒子证明那肝活体检视在与淋巴瘤 / 白血病能引起尖锐的肝失败的象 NK 一样 T 房间诊断肝的尖锐的肝失败,和那渗入的不平常的原因是必要的。 | Evan S Dellon Shannon R Morris Wozhan Tang Cherie H Dunphy Mark W Russo | 2006 | World Journal of Gastroenterology2006,12,25: | 5 |
| 5 | Beyond first-line chemotherapy for advanced pancreatic cancer:An expanding array of therapeutic options?显示文摘While an increasing number of therapeutic options are now available for the first-line treatment of locally advanced or metastatic pancreatic cancer,the optimal choice for treatment in the second-line setting and beyond is less well defined.A variety of cytotoxic agents,either alone or in combination,have been evaluated,although primarily in the context of small single-arm or retrospective studies.Most regimens have been associated with median progression-free survival rates in the range of 2-4 mo and overall survival rates between 4-8mo,highlighting the very poor prognosis of patients who are candidates for such treatment.Targeted therapies studied in this chemotherapy-refractory setting,meanwhile,have produced even worse efficacy results.In the current article,we review the clinical evidence for treatment of refractory disease,primarily in patients who have progressed on front-line gemcitabine-based chemotherapy.In the process,we highlight the limitations of the available data to date as well as some of the challenges in designing appropriate clinical trials in this salvage setting,including how to select an appropriate control arm given the absence of a wellestablished reference standard,and the importance of incorporating predictive biomarkers and quality of life measures whenever possible into study design. | Evan J Walker Andrew H Ko | 2014 | World Journal of Gastroenterology2014,20,9: | 2 |
| 6 | Effect of a Patient Education Intervention on Asthma Control and Patient-Doctor Relationship显示文摘 | Yu-Qin Zeng David H Au Shan Cai Evan Carey Fen Jiang Yan Chen Zhi-Jun Liu Ping Chen | 2018 | Chinese Medical Journal2018,,9: | 2 |
| 7 | Rapid Voltammetric Method for the Estimation of Tocopherols and Antioxidants in Oils and Fats显示文摘 | Mcibride D H Evans H D | 1973 | Anal Chem1973,45,: | 2 |
| 8 | Comparison of the efficacy and safety of rosuvastatin versus atorvastatin , simvastatin , and pravastatin across doses (STELLAR * * STELLAR = Statin Therapies for Elevated Lipid Levels compared Across doses to Rosuvastatin. Trial)显示文摘 | Peter H Jones Michael H Davidson Evan A Stein Harold E Bays James M McKenney Elinor Miller Valerie A Cain James W Blasetto | 2003 | The American Journal of Cardiology2003,,2: | 2 |
| 9 | Gene transfer approaches to the healing of bone and cartilage显示文摘 | Lieberman J R Ghivizzani S C Evans C H | 2002 | Mol Ther2002,6,: | 1 |
| 10 | The experimental behavior of double skin composite elements 显示文摘 | WRIGHT H ODUYEMI T EVANS H R | 1991 | Journal of Constructional Steel Research1991,,19: | 1 |
| 11 | Novel MMC Microstructure with Tailored Distribution of the Reinforcing Phase 显示文摘 | Peng H X Fan Z Evans J R G | 2001 | Journal of Microscopy2001,201,: | 1 |
| 12 | Forest litter production,chemistry,and decomposition following two years of free air CO2 enrichment显示文摘 | ADRIEN C F ANDREW S A EVAN H D | 2001 | Ecology2001,82,2: | 1 |
| 13 | The mycobiota of the weed Mikania micrantha in southern Brazil with particular reference to fungal pathogens for biological control显示文摘 | Barreto R W Evans H C | 1995 | Mycol Res1995,,3: | 1 |
| 14 | The experimental behaviour of double skin composite elements显示文摘 | WRIGHT H D ODUYEMI T O S EVANS H R | 1991 | Journal of Constructional Steel Research1991,19,2: | 1 |
| 15 | HATs on and beyond chromatin 显示文摘 | Chert H Tini M Evans RM | 2001 | Curr Opin Cell Biol2001,13,2: | 1 |
| 16 | The design of double skin composite elements 显示文摘 | Wright H D Oduyemi T O S Evans H R | 1991 | Journal of Constructional Steel Research1991,19,2: | 1 |
| 17 | Shear lag in composite box girders of complex cross section显示文摘 | Evans H R Ahmad M K Kristek V | 1993 | J Constructional Steal Research1993,24,3: | 1 |
| 18 | The management of urinary calculi in pregnancy显示文摘 | Evans H J Wollin T A | 2001 | Curr Opin Urol2001,11,4: | 1 |
| 19 | The global topography mission gains momentum 显示文摘 | Farr T Evans D zebker H | 1995 | Eos Trans American Geophys Union1995,76,21: | 1 |
| 20 | Residual stresses in meta/ceramic bonded strips 显示文摘 | Hsueh C H Evans A G | 1985 | Journal of the American Ce- ramic Society1985,68,5: | 1 |