|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 精氨酸酶-内皮型一氧化氮合酶失衡促进慢性间歇性缺氧期间的内皮功能障碍显示文摘慢性间歇性缺氧(chronic intermittent hypoxia,CIH)是阻塞性睡眠呼吸暂停的主要特征,与血管功能损害相关,尽管其不会改变血管对一氧化氮供体的反应。该研究旨在探讨精氨酸酶是否促进CIH大鼠血管内皮功能障碍。 | 刘莉 叶鹏 Krause BJ Del Rio R Moya EA Marquez-Gutierrez M Casanello P Iturriaga R | 2015 | 中华高血压杂志2015，23，5： | 2 |
| 2 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006，12，28： | 2 |
| 3 | Clinical significance of'anti-HBc alone'in human immunodeficiency virus-positive patients显示文摘AIM:To determine the prevalence and clinical relevance of isolated antibodies to hepatitis B core antigen as the only marker of infection('anti-HBc alone')among human immunodeficiency virus(HIV) type-1 infected patients.Occult hepatitis B infection frequency was also evaluated. METHODS:Three hundred and forty eight histories from 2388 HIV-positive patients were randomly reviewed.Patients with serological markers of hepatitis B virus(HBV)infection were classified into three groups:past hepatitis,'anti-HBc alone'and chronic hepatitis.Determination of DNA from HBV,and RNA and genotype from hepatitis C virus(HCV)were performed on'anti-HBc alone'patients. RESULTS:One hundred and eighty seven(53.7%) HIV-positive patients had markers of HBV infection: 118 past infection(63.1%),14 chronic hepatitis (7.5%)and 55'anti-HBc alone'(29.4%).Younger age[2.3-fold higher per every 10 years younger;95% confidence intervals(CI)1.33-4.00]and antibodies to HCV infection[odds ratio(OR)2.87;95%CI 1.10-7.48]were factors independently associated with the'anti-HBc alone'pattern.No differences in liver disease frequency were detected between both groups. Serum levels of anti-HBs were not associated with HCV infection(nor viral replication or HCV genotype),or with HIV replication or CD4 level.No'anti-HBc alone' patient tested positive for HBV DNA. CONCLUSION:'Anti-HBc alone'prevalence in HIVpositive patients was similar to previously reported data and was associated with a younger age and with antibodies to HCV infection.In clinical practice,HBV DNA determination should be performed only in those patients with clinical or analytical signs of liver injury. | M~aTeresa Pérez-Rodríguez Bernardo Sopea Manuel Crespo Alberto Rivera Teresa González del Blanco Antonio Ocampo César Martínez-Vázquez | 2009 | World Journal of Gastroenterology2009，15，10： | 2 |
| 4 | Dendritic cell-mediated cross presentation of antigens derived from colon carcinoma cells exposed to a highly eytotoxie multidrug regimen with gemcitabine, oxaliplatin, 5 fluorouracil,and leucovorin, elicits a powerful human antigenspecific CTL response with antitumor activity in vitro显示文摘 | Correale P Cusi M G Del Vecchio M T Aquino A Prete S P Tsang K Y | 2005 | J Immunol2005，175，： | 1 |
| 5 | Coloring of titanium through laser oxidation: Comparative study with anodizing 显示文摘 | Perez Del P Ferndndez-Pradas J M Serra P | 2004 | Surface and Coatings Technology2004，187，1： | 1 |
| 6 | Guidelines for the early management of adults withischemic stroke: a guideline from the American Heart Association/American Stroke Association StrokeCouncil, ClinicalCardiology Council, CardiovascularRadiology and Inter vent ion Council, and theAtherosclerotic Peripheral VascularDisease andQualityof CareOutcomeinResearchlnterdisciplinary Working Groups:the American Academy of Neurologyaffirms the value of this guideline as an educationaltool for neurologists 显示文摘 | ADAMS H P JR DEL ZOPPO G ALBER TS M J | 2007 | Stroke2007，38，： | 1 |
| 7 | The Toxoplasma gondii bradyzoite antigens BAG1 and MAG1 induce early humoral and cell-mediated immune responses upon human infection 显示文摘 | Di Cristina M Del Porto P Buffolano W | 2004 | Microbes Infect2004，6，2： | 1 |
| 8 | Identification of the membrane-type matrix metalloproteinase MT1-MMP in osteoclasts 显示文摘 | Sato T del Carmen Ovejero M Hou P | 1997 | J Cell Sci1997，110，： | 1 |
| 9 | Dissolving polymer microneedle patches for influenza vaccina- tion显示文摘 | Sullivan S P Koutsonanos D G del Pilar Martin M | 2010 | Nat Med2010，16，8： | 1 |
| 10 | Spontaneous resolution of a shallow detachment of the macula in a highly myopic eye显示文摘 | Polito A Lanzetta P Del Borrello M | | 0，，4： | 1 |
| 11 | Antioxidant activity of different fractions of Spirulina platensis protein extract显示文摘 | Estrada P Bescos B P Villar del Fresno A M | 2001 | Farmaco2001，56，： | 1 |
| 12 | Between subjects variability in haemoglobin and dose are not associated with the erythropoiesis-stimulating agent used to treat anaemia in dialysis: a meta-analysis显示文摘 | Pérez-Ruixo J J Cucala-Ramos M Garcia-Gonzalo E Del Val Romero B Valveny N | 2013 | Br J Clin Pharmacol2013，75，： | 1 |
| 13 | 3D finite element simu- lation of the opening movement of the mandible in healthy and pathologic situations 显示文摘 | DEL PALOMAR A P DOBLARE M | 2006 | Journal of Biomechanical Engi- neering-Transactions of the ASME2006，128，2： | 1 |
| 14 | Bacterioplankton community structure:protists cntrol net production and the proportion of active bacteria in a coastal marine community 显示文摘 | del Giorgio P A Gasol J M Vaqu D | 1996 | Limnol Oceanogr1996，41，6： | 1 |
| 15 | Shift in Japanese encephalitis virus (JEV) genotype circulating in northern Vietnam: implications for frequent introductions of JEV from Southeast Asia to East Asia显示文摘 | Nga P T del Carmen Parquet M Cuong V D | 2004 | J Gen Virol2004，85，6： | 1 |
| 16 | Relationship between crowns and the periodontium:a literature update显示文摘 | Kosyfaki P del Pilar Pinilla Martín M Strub JR | | 0，，02： | 1 |
| 17 | Molecular diagnosis of infective endocarditis by re- al-time broad-range polymerase chain reaction (PCR) and sequencing directly from heart valve tissue 显示文摘 | Marin M Mufioz P Sdnchez M del Rosal M Alcal6 L Rodrlguez-Cr6ixems M Bouza E Group for the Manage- ment of Infective Endocarditis of the Gregorio Marafi6n Hospital | 2007 | Medicine2007，86，4： | 1 |
| 18 | Stabilization of All-trans-lycopene from Tomato by Encapsulation Using Cyclodextrins显示文摘 | BLANCH G P RUTZ DEL CASTILLO M L CAJA M M et at | 2007 | Food Chem2007，105，4： | 1 |
| 19 | Analysis of the optical properties of the Orinoco River plume by absorption and fluorescence spectroscopy显示文摘 | Del Castillo C E Coble P G Morell J M | 1999 | Mar Chern1999，66，12： | 1 |
| 20 | Does preoperative stoma marking and education by the enterostomal thera- pist affect outcome显示文摘 | Bass E M Del P A Tan A | 1997 | Dis Colon Rectum1997，40，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员