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| 1 | Antenna-assisted picosecond control of nanoscale phase transition in vanadium dioxide显示文摘Nanoscale devices in which the interaction with light can be configured using external control signals hold great interest for next-generation optoelectronic circuits.Materials exhibiting a structural or electronic phase transition offer a large modulation contrast with multi-level optical switching and memory functionalities.In addition,plasmonic nanoantennas can provide an efficient enhancement mechanism for both the optically induced excitation and the readout of materials strategically positioned in their local environment.Here,we demonstrate picosecond all-optical switching of the local phase transition in plasmonic antenna-vanadium dioxide(VO_(2))hybrids,exploiting strong resonant field enhancement and selective optical pumping in plasmonic hotspots.Polarization-and wavelength-dependent pump–probe spectroscopy of multifrequency crossed antenna arrays shows that nanoscale optical switching in plasmonic hotspots does not affect neighboring antennas placed within 100 nm of the excited antennas.The antenna-assisted pumping mechanism is confirmed by numerical model calculations of the resonant,antenna-mediated local heating on a picosecond time scale.The hybrid,nanoscale excitation mechanism results in 20 times reduced switching energies and 5 times faster recovery times than a VO_(2) film without antennas,enabling fully reversible switching at over two million cycles per second and at local switching energies in the picojoule range.The hybrid solution of antennas and VO_(2) provides a conceptual framework to merge the field localization and phase-transition response,enabling precise,nanoscale optical memory functionalities. | Otto L Muskens Luca Bergamini Yudong Wang Jeffrey M Gaskell Nerea Zabala CH de Groot David W Sheel Javier Aizpurua | 2016 | Light(Science & Applications)2016，5，1： | 5 |
| 2 | FK506对实验性卒中疗效的系统评价和Meta分析显示文摘FK506是治疗急性卒中的一种候选用药。决定一种药物是否可以用于临床试验,应当以全面的、无偏倚的动物实验数据的评估为依据,同时还应考虑到这些数据的局限性。这种评估不但应包括药物疗效,而且也应包括药效在体内的特征和局限性。本研究应用系统评价和Meta分析的方法对FK506在卒中动物模型中保护作用的证据进行评价。总共纳入了29个描述了实验步骤的研究,包括1759只动物。结果显示,FK506疗效的点估计值(结局指标的改善)是31.3%[95%CI(0.272-0.354)]。在采用氯胺酮麻醉和短暂性脑缺血的动物实验中,FK506的疗效更高,在使用大鼠,合并其他疾病的动物及仅以梗死面积为疗效指标的实验中,FK506疗效较低。已发表的实验研究质量均接近临床试验标准,但在高质量的研究中,FK506的疗效较低。FK506在实验性脑卒中的研究中,虽然显示出有明显的疗效,但是应注意由于研究质量和可能的发表偏倚等冈素的影响,FK506的疗效可能被过高估计。 | Malcolm R Macleod Tori O’Collins Laura L Horky David W Howells Geoffrey A Donnan 段建钢 | 2006 | 中国循证医学杂志2006，6，6： | 3 |
| 3 | Association of telomere length with authentic pluripotency of ES/iPS cells显示文摘Telomerase 和 telomeres 为干细胞的不定的复制是重要的。最近,体的房间的 telomeres 被发现是 reprogrammed 在导致的 pluripotent 干细胞(iPSCs ) 伸长。然而,在在胚胎的干细胞(转换字符) 或 iPSCs 的 vivo 的发展 pluripotency 的 telomeres 的角色直接没被探讨。我们证明有长 telomeres 的转换字符展出真发展 pluripotency,由完全的转换字符小狗以及 germline 能干的怪物的产生证实了在啮齿类动物可得到的最紧的测试。有短 telomeres 的转换字符显示出减少的 teratoma 形成和怪物生产,并且没能产生完全的转换字符小狗。Telomere 长度高度被相关(r > 0.8 ) 与转换字符的发展 pluripotency。短 telomeres 减少 proliferative 率或转换字符的能力,改变与 telomere epigenetics 有关的基因的表示,为 embryogenesis 重要的下面调整基因并且破坏细菌房间区别。而且,有更长的 telomeres 的 iPSCs 与短 telomeres 比那些与更高的效率产生怪物。我们功能的 telomeres 为 ESCs/iPSCs 的发展 pluripotency 是必要的并且建议那 telomere 长度可以提供一个珍贵标记评估干细胞 pluripotency 的数据表演,特别地当紧测试不是可行的时。 | Junjiu Huang Fang Wang Maja Okuka Na Liu Guangzhen Ji Xiaoying Ye Bingfeng Zuo Minshu Li Ping Liang William W Ge John CM Tsibris David L Keefe Lin Liu | 2011 | Cell Research2011，21，5： | 3 |
| 4 | DNA vaccination of infants in the presence of maternal antibody: a measles model in the primate显示文摘 | Mary Premenko-Lanier Paul A Rota Gary Rhodes David Verhoeven Dan H Barouch Nicholas W Lerche Norman L Letvin William J Bellini Michael B McChesney | 2003 | Virology2003，，1： | 2 |
| 5 | Evaluation and treatment of internal impingement of the shoulder in overhead athletes显示文摘One of the most common pathologic processes seen in overhead throwing athletes is posterior shoulderpain resulting from internal impingement. 'Internal impingement' is a term used to describe a constellation of symptoms which result from the greater tuberosity of the humerus and the articular surface of the rotator cuff abutting the posterosuperior glenoid when the shoulder is in an abducted and externally rotated position. The pathophysiology in symptomatic internal impingement is multifactorial,involving physiologic shoulder remodeling,posterior capsular contracture,and scapular dyskinesis. Throwers with internal impingement may complain of shoulder stiffness or the need for a prolonged warm-up,decline in performance,or posterior shoulder pain. On physical examination,patients will demonstrate limited internal rotation and posterior shoulder pain with a posterior impingement test. Common imaging findings include the classic 'Bennett lesion' on radiographs,as well as articular-sided partial rotator cuff tears and concomitant SLAP lesions. Mainstays of treatment include intense non-operative management focusing on rest and stretching protocols focusing on the posterior capsule. Operative management is variable depending on the exact pathology,but largely consists of rotator cuff debridement. Outcomes of operative treatment have been mixed,therefore intense non-operative treatment should remain the focus of treatment. | Keith T Corpus Christopher L Camp David M Dines David W Altchek Joshua S Dines | 2016 | World Journal of Orthopedics2016，7，12： | 2 |
| 6 | The carbon we do not see-the impact of low molecular weight compounds on carbon dynamics and respiration in forest soils:a review显示文摘 | PATRICK A W DAVID L J FINLAY R | 2005 | Soil Biology & Biochemistry2005，37，： | 1 |
| 7 | Carbon and nitrogen assimilation in relation to yield : mechanisms are the key to understanding production systems 显示文摘 | David W L | 2002 | Journal of Experimental Botany2002，53，370： | 1 |
| 8 | Optical-cell evidencefor superheated ice under gas-hydrate-forming Conditions显示文摘 | STERN L A DAVID L H DURHAM W B | 1998 | Journal of Physical Chemistry1998，102，： | 1 |
| 9 | Refractive optical sys- tems for irradiance redistribution of collimated radiation: their design and analysis 显示文摘 | Patrick W Rhodes David L Shealy | 1980 | Appl Opt1980，19，20： | 1 |
| 10 | Medication er- rors and adverse drug events in pediatric inpatients显示文摘 | Rainu K David W Christopher L | 2001 | JA- MA2001，285，16： | 1 |
| 11 | Growth response of selected vegetable crops to spent mushroom compost appli- cation in a controlled environment显示文摘 | SHERRY I-I W VIRGINIA I L DAVID L C | 1984 | Plant and Soi11984，82，1： | 1 |
| 12 | A GCM parameterization for bimodal size spectra and ice mass removal rates in mid latitude cirrus clouds显示文摘 | Dorothea Ivanova David L Mitchell W Patrick Arnott | 2001 | Atmospheric research2001，，5960： | 1 |
| 13 | A Reviewand Analysis of Current Computer-Aided Fixture DesignApproaches 显示文摘 | B O Y L E Iain R O N G Yiming B R O W N David C | 2011 | Robotics and Computer-Integrated Manufacturiiig2011，27，1： | 1 |
| 14 | Organic compost and manufactured fertilizers: economics and ecology 显示文摘 | David C W James P M Cesard L S | 2011 | Integrating Agriculture Conservation and Ecotourism2011，1，： | 1 |
| 15 | Education in the clouds How colleges and universities are leveraging cloud computing显示文摘 | DAVID C W RUSTY L J | 2010 | Technological Developments in Networking Education and Automation2010，，3： | 1 |
| 16 | Origin and evolution of Japanese encephalitis virus in southeast asia显示文摘 | Solomon T Ni H L David W C Beasley | 2003 | J Virol2003，77，5： | 1 |
| 17 | On breaking a huffman code 显示文摘 | Gillman David W Mohtashemi Mojdeh Rivest Ronald L | 1996 | IEEE Transactions on Information Theory1996，42，： | 1 |
| 18 | Importance of the dome and poste- rior wall as evidenced by bone density mapping in the acetabulum 显示文摘 | Omri L David W Michael H | 2011 | Clinical Biomechanics2011，26，3： | 1 |
| 19 | The effects of stabilizers on the bath stability of electroless Ni deposition and the deposit 显示文摘 | Luan Ben L Shoesmith David W | 2004 | Applied Surface Science2004，229，： | 1 |
| 20 | Soil acidification used as a management strategy to reduce nitrate losses from agricultural land显示文摘 | Sarah J K David W David L J | 2005 | Soil Biology & Biochemistry2005，37，： | 1 |
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