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| 1 | Epithelial cells with hepatobiliary phenotype:Is it another stem cell candidate for healthy adult human liver?显示文摘AIM:To investigate the presence and role of liver epithelial cells in the healthy human adult liver.METHODS:Fifteen days after human hepatocyte primary culture,epithelial like cells emerged and started proliferating.Cell colonies were isolated and sub-cultured for more than 160 d under specific culture conditions.Cells were analyzed for each passage using immunofluorescence,flow cytometry and reverse transcription-polymerase chain reaction(RT-PCR).RESULTS:Flow cytometry analysis demonstrated that liver epithelial cells expressed common markers for hepatic and stem cells such as CD90,CD44 and CD29 but were negative for CD34 and CD117.Using immunofluorescence we demonstrated that liver epithelial cells expressed not only immature(α-fetoprotein)but also differentiated hepatocyte(albumin and CK-18)and biliary markers(CK-7 and 19),whereas they were negative for OV-6.RT-PCR analysis confirmed immunofluorescence data and revealed that liver epithelial cells did not express mature hepatocyte markers such as CYP2B6,CYP3A4 and tyrosine amino-transferase.Purified liver epithelial cells were transplanted into SCID mice.One month after transplantation,albumin positive cell foci were detected in the recipient mouse parenchyma.CONCLUSION:According to their immature and bipotential phenotype,liver epithelial cells might represent a pool of precursors in the healthy human adult liver other than oval cells. | Dung Ngoc Khuu Mustapha Najimi Etienne M Sokal | 2007 | World Journal of Gastroenterology2007，13，10： | 3 |
| 2 | Generating Finite - state Transducers for Semi-structured Data Extraction from the Web显示文摘 | Hsu C N Dung M T | 1998 | Information Systems1998，23，8： | 1 |
| 3 | Development of defined mixed-culture fungal fermentation starter granulate for controlled production of rice wine显示文摘 | Dung N T P Rombouts F M Nout M J R | 2005 | Innovative Food Science and EmergingTechnologies2005，，6： | 1 |
| 4 | Selective formation of para-xylene over H-ZSM-5 coated with polycrystalline siliealite crystals显示文摘 | DUNG V V MANABU M NORIKAZU N | 2006 | J Catal2006，243，2： | 1 |
| 5 | Development of defined mixed-culture fangal fermentation starter granulate for controlled production of rice wine 显示文摘 | DUNG N T P ROMBOUTS F M NOUT M J R | 2005 | Innovative Food Science and Emerging Technologies2005，6，4： | 1 |
| 6 | Identification of Edwardsiella ictaluri from diseased freshwater catfish,Pangasius hypophthalmus (Sauvage),cultured in the Mekong Delta,Vietnam显示文摘 | Crumlish M Dung T T Turnbull J F | 2002 | J Fish Dis2002，25，12： | 1 |
| 7 | Adaptive neuro- fuzzy and fuzzy decision tree classifiers as applied sea- floor characterization显示文摘 | Stepnowski A Mosynski M Dung T V | 2003 | Acoustical Physics2003，49，2： | 1 |
| 8 | MRI findings in Hirayama disease显示文摘 | Raval M Kumari R Dung A A | 2010 | Indian J Radiol Imaging2010，20，4： | 1 |
| 9 | Effects of concentration on the performance of erbium-doped fiber amplifiers 显示文摘 | PIOTR M DUNG N JACEK C | 1997 | Journal of Lightzoave Technology1997，15，1： | 1 |
| 10 | On the acceptability of arguments and its fundamental role in nonmonotonic reasoning, logic programming and n-person games显示文摘 | Dung P M | 1995 | Artificial Intelligence1995，77，： | 1 |
| 11 | An abstract, argumentation-theoretic approach to default reasoning显示文摘 | Bondarenko A Dung P M Kowalski R A | 1997 | k Artificial Intelligence1997，97，： | 1 |
| 12 | Generating finite-state trans- ducers for semi-structured data extraction from the web显示文摘 | Hsu C N Dung M | 1998 | Information System1998，，： | 1 |
| 13 | On the acceptability of arguments and its fundamental role in nonmonotonic reasoning, logic programming and n-person games显示文摘 | Dung P M | 1995 | Artificial Intelligence1995，77，： | 1 |
| 14 | Tumor Necrosis Factor α Is Toxic to Embryonic Mesencephalic Dopamine Neurons显示文摘 | Susan O McGuire Zao Dung Ling Jack W Lipton Caryl E Sortwell Timothy J Collier Paul M Carvey | 2001 | Experimental Neurology2001，，2： | 1 |
| 15 | Functionality of selected strains of moulds and yeasts from Vietnamese rice wine starters显示文摘 | N T P Dung F M Rombouts | 2006 | Food Microbiology2006，，23： | 1 |
| 16 | Production systems need negation as failure显示文摘 | Dung P M Mancarella P | 2002 | IEEE Transactions on Knowledge and Data Engineering2002，14，2： | 1 |
| 17 | Investigation on Slenderness Ratios of Built-Up Compression Members显示文摘 | Liu Juiling Dung M Lue Lin Ching H | 2009 | Journal of Constructional Steel Research2009，，： | 1 |
| 18 | Water soluble derivatives obtained by controlled chemical modifications of chitosan显示文摘 | Dung P Milas M Rinaudo M | 1994 | Carbohydr Polym1994，24，3： | 1 |
| 19 | Eurological manifestations of dengue infection显示文摘 | Dung N M Vaughn D W | 2000 | Lancet2000，355，2： | 1 |
| 20 | Water soluble derivatives obtained by controlled chemical modifications of chitosan 显示文摘 | Dung PL Milas M Rinaudo M et od | 1994 | Carbohydrate Polymers1994，24，： | 1 |
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