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| 1 | Chinese Stroke Center Alliance:a national effort to improve healthcare quality for acute stroke and transient ischaemic attack:rationale,design and preliminary findings显示文摘Background In June 2015,the Chinese Stroke Association(CSA)initiated the Chinese Stroke Center Alliance(CSCA)to establish the national hospital-based stroke care quality assessment and improvement platform.This article outlines its objectives,operational structure,patient population,quality improvement(QI)intervention tools,data elements,data collection methodology and current patient and hospital data.Methods The CSCA is a national,hospital-based,multicentre,voluntary,multifaceted intervention and continuous QI initiative.This multifaceted intervention includes stroke centre development,written care protocols,workshops and a monitoring/feedback system of evidencebased performance measures.The data coordinating centre of the CSCA resides at the China National Clinical Research Center for Neurological Diseases,Beijing Tiantan Hospital.results As of July 2017,1576 hospitals in China have contributed detailed clinical information to serve as a benchmark for the stroke care quality of 433264 patients with acute stroke/transient ischaemic attacks(TIA),including 352572(81.38%)acute ischaemic stroke,30362(7.01%)TIA,42080(9.71%)spontaneous intracranial haemorrhage,5505(1.27%)subarachnoid haemorrhage and 2745(0.63%)not specified stroke.Conclusion The CSCA programme is designed to establish a continuous national stroke registry and help healthcare providers develop stroke centres and treat patients in a consistent manner in accordance with accepted national guidelines and,ultimately,improve patient outcomes.It supports the CSA mission to reduce stroke burden in China. | Yongjun Wang Zixiao Li Yilong Wang Xingquan Zhao Liping Liu Xin Yang Caiyun Wang Hongqiu Gu Fuying Zhang Chunjuan Wang Ying Xian David Z Wang Qiang Dong Anding Xu Jizong Zhao Chinese Stroke Center Alliance investigators | 2018 | Stroke & Vascular Neurology2018，3，4： | 38 |
| 2 | The spatial distribution of major and trace elements of surface sediments in the northeastern Beibu Gulf of the South China Sea显示文摘A multi-index analysis including grain size, major and trace elements is performed on the surface sediments from the northeastern Beibu Gulf to trace the sources of the sediments and to understand the controlling factors for elements distribution. The mean grain size exhibits a wide variation ranging from 0.09Φ to 8.05Φ with an average value of 5.33Φ. The average contents of major elements descend in an order of c(SiO_2)>c(Al_2O_3)>c(Fe_2O_3)>c(CaO)>c(MgO)>c(K_2O)>c(Na_2O)>c(TiO_2)>c(P_2O_5)>c(MnO), while those of trace elements exhibit a descending order of c(Sr)>c(Rb)>c(V)>c(Zn)>c(Cr)>c(Pb)>c(Ni)>c(Cu)>c(As). On the basis of elementary distribution characteristics and statistical analyses, the study area is divided into the four zones: Zone I is located in the northeastern coastal area of the gulf, which receives large amount of fluvial materials from local rivers in Guangxi and Guangdong, China, and the Qiongzhou Strait; Zone Ⅱ is located in the center of the study area, where surface sediments exhibits a multiple source; Zone Ⅲ is located in the Qiongzhou Strait, where surface sediments are dominated by materials from the Zhujiang River and Hainan; Zone IV is located in the southwest of the study area, where surface sediments are mainly originated from the Red River and Hainan. The statistical analyses of sediment geochemical characteristics reveal that the grain size, which is mainly influenced by hydrodynamics and mineral composition of terrigenous materials, is the leading factor controlling the elementary distribution.Meanwhile, impacts from anthropogenic activities and marine biogenic process will also be taken into consideration. | Qian Ge George Z Xue Liming Ye Dong Xu Jianru Zhao Fengyou Chu | 2019 | Acta Oceanologica Sinica2019，38，3： | 5 |
| 3 | Effects of a memory enhancing peptide on cognitive abilities of brain-lesioned mice: additivity with huperzine A and relative potency to tacrine显示文摘 | Xu Z Zheng H Law SL Dong So D Han Y Xue H | 2006 | 中国生物学文摘2006，20，10： | 3 |
| 4 | Is tenecteplase ready to replace alteplase to treat acute ischaemic stroke? The knowns and unknowns显示文摘Tenecteplase(TNKase,TNK-tPA or TNK)is a thrombolytic agent derived from the tissue plasminogen activator(tPA).It is a 527-amino acid glycoprotein developed by replacing three amino acids at the T,N and K positions of the glycoprotein structure of tPA under genetic recombinant technology.After replacing threonine 103 with asparagine,asparagine 117 with glutamine and a tetra-alanine at amino acids 296–299,TNK is about eightfold more potent in dissolving clot,80-fold higher resistance to plasminogen activator inhibitor-1 and 14-fold enhanced relative fibrin specificity,and with a longer half-life(20 min).1 Hence,TNK is administered as a single intravenous bolus. | Yi Dong Yi Sui Xin Cheng David Z Wang | 2022 | Stroke & Vascular Neurology2022，7，1： | 3 |
| 5 | Mechanisms of cell death in hypoxia/reoxygenation injury显示文摘 | Saikumar P Dong Z Weinberg JM | | 0，，： | 2 |
| 6 | A study of the short wave components in computational acoustics 显示文摘 | Tam C K W Webb J C Dong Z | 1993 | Journal of Computational Acoustics1993，1，： | 2 |
| 7 | Cancer mortality among silicostics in Chinas metallurgical industry 显示文摘 | Wang Z Dong D Liang X | 1996 | Inter J Epidemiol1996，25，5： | 2 |
| 8 | Estimate of total CO2 output from desertified sandy land in China显示文摘 | Duan Z Xiao H Dong Z | 2001 | Atmospheric Environment2001，35，： | 2 |
| 9 | The development of metallic behavior in clusters 显示文摘 | VENKATESAN T RAJESWARI M DONG Z W | 1998 | Phil Trans R Soc1998，356，： | 2 |
| 10 | 王红阳院士发现肝癌患者中红细胞增多症的分子机制显示文摘近日国际著名肝脏疾病杂志Hepatology在线发表了第二军医大学附属东方肝胆外科医院王红阳院士研究成果,癌细胞来源的促红细胞生成素在肝细胞癌的进展中发挥一定的作用,并且EPO/EPOR可被视为具有红细胞增多症的肝癌患者的一个治疗靶标。红细胞增多症(Erythrocytosis)与许多类型的肿瘤相关,包括肾细胞癌、脑膜瘤以及肝细胞癌(HCC)。 | Ke S Chen S Dong Z | 2016 | 胃肠病学和肝病学杂志2016，25，12： | 2 |
| 11 | Effect of Interracial Free Energy on Hydriding Reaction of Mg-Ni Thin Films 显示文摘 | Ouyang L Z Ye SY Dong H W | 2007 | ApplPhysLett2007，90，02： | 1 |
| 12 | Identification of coumarinenriched Japanese green teas and their particular flavor using electronic nose显示文摘 | YANG Z DONG F SHIMIZU K | 2009 | Journal of Food Engineering2009，92，： | 1 |
| 13 | Study of polystyrene and acrylomtrile-styrene copolymer as special beta-nucleating agents to induce the crystallization of isotactic polypropylene 显示文摘 | SU Z Q DONG M GUO Z X | 2007 | Macromolecules2007，40，： | 1 |
| 14 | A Nitrogen-Fixing Endophyte of Sugarcane Stems(A New Role for the Apoplast)显示文摘 | Dong Z Canny M J McCully M E | 1994 | American Society of Plant Biologists1994，105，4： | 1 |
| 15 | Role of eIF3a in regulating cell cycle progression显示文摘 | Dong Z Z Liu Z Q Ping C | 2009 | Exp Cell Res2009，315，11： | 1 |
| 16 | Estrogen-enhanced peptidylarginine deiminase type Ⅳ gene (PADI4) expression in MCF-7 cells is mediated by estrogen receptor-alphapromoted transfactors activator protein-1, nuclear factor-Y, and Spl 显示文摘 | Dong S Zhang Z Takahara H | 2007 | Mol Endocrinol2007，21，7： | 1 |
| 17 | Variations of horizontal and vertical velocities over two-dimensional transverse dunes: A wind tunnel simulation of the effect of windward slope显示文摘 | Qian G Q Dong Z B Luo W Y | 2009 | Journal of AridEnvironments2009，73，： | 1 |
| 18 | Regulation of mitochondrial morphological dynamics during apoptosis by Bcl-2 family proteins:a key in Bak显示文摘 | Brooks C Dong Z | 2007 | Cell Cycle2007，6，24： | 1 |
| 19 | Mesenchymal stem cell-based repair of articular cartilage with polyglycolic acid-hydroxyapatite biphasic scaffold显示文摘 | Zhou X Z Leung V Y Dong Q R | 2008 | Int J Artif Organs2008，31，6： | 1 |
| 20 | Investigation on POM reaction in a new perovskite membrane reactor 显示文摘 | Dong H Shao Z P Xiong G X | 2001 | Catal Today2001，67，： | 1 |
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