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| 1 | 人参减少 γ射线照射的淋巴细胞微核量(英文)显示文摘目的 评价中国人参对减少辐射诱导的人周围血 G0 期淋巴细胞 (PBL)微核量的作用。方法 采用细胞因子阻滞的微核法检测健康志愿者的血标本。体外 1 37Cs照射之前 ,每份血标本的单个核细胞培养以不同浓度 (0~ 2 0 0 0μg· m l- 1 )的人参根水提取物孵育 2 4 h。结果 (1)在 0 Gy时 ,每 10 0 0个双核 (BN )细胞的微核量是 11.3± 2 .7,人参水提取物≥ 5 0 0μg· ml- 1 时微核量下降 ,但微核量和人参水提取物的浓度之间的差异是显著的。 (2 )单独射线照射显著增加微核量 ,当暴露于 1Gy的照射时 ,随着培养介质中人参水提取物浓度的增加 ,微核量呈显著的线性降低 (R2 =0 .0 5 ,P =0 .0 0 2 ) ;对暴露于 1Gy辐射诱导的微核量 ,人参水提取物浓度在 15 0 0μg· m l- 1 时减少 4 6 .6 % ,浓度在 2 0 0 0μg·m l- 1时减少 5 7.6 % ;对暴露于 2 Gy辐射诱导的微核量的减少呈更强的线性相关 (R2 =0 .7,P=0 .0 0 0 1) ;(3)微核数据分析的结果呈现出与 Poisson模型相关的过度离散趋势。结果表明 :(1)人参水提取物浓度达 2 0 0 0 μg· ml- 1时 ,对 PBL 细胞毒作用无明显影响 ;(2 )人参水提取物浓度在 5 0 0 μg· ml- 1和 2 0 0 0 μg· ml- 1之间时 ,对抗 1 37Cs照射诱导的 MN发挥保护作用。 | 李同光 Ron R Allison Kevin F O'Brien Prabhaker G Khazanie Larry J Dobbs Jr. Peter J Kragel | 2004 | 新乡医学院学报2004，21，3： | 3 |
| 2 | Vacuum electronic high power terahertz sources显示文摘 | BOOSKE J DOBBS R JOYE C | | 0，，01： | 3 |
| 3 | Measure- ment of functional microcirculatory geometry and velocity distributions using automated image analysis 显示文摘 | Dobbe J G G Streekstra G J Atasever B | 2008 | Medical Biologic Engineer Computer2008，46，7： | 1 |
| 4 | Validation and application of an automated rheoscope for measuring red blood cell deformability distributions in different species显示文摘 | J G G Dobbe M R Hardeman G J Streekstra C A Grimbergen | 2004 | Biorheology2004，，2： | 1 |
| 5 | Temkin vacuum electronics high power terahertz sources 显示文摘 | John H Booske Richard J Dobbs Colin D Joye Carol L Kory George R Neil Gunn-sik Park Jaehun Park Richard J | 2011 | IEEE transactions on terahertz science and technolo- gy2011，1，1： | 1 |
| 6 | Antitumour copper ( U ) salicylaldehyde benzoyhydrazone complexes 显示文摘 | W Ainscough E M Brodie A J Dobbs A | 1998 | Inorg Chim Acta1998，26，7： | 1 |
| 7 | Selective posterior thoracic fu- sions for adolescent idiopathic scoliosis comparison of hooks versus pedicle screws显示文摘 | Dobbs MB Lenke LG Kim Y J | 2006 | Spine2006，20，： | 1 |
| 8 | Identification of a novel antigen on the apical surface of rat alveolar epithelial type Ⅱ and Clara cells 显示文摘 | Boylan G M Pryde J G Dobbs L G | 2001 | Am J Physiol Lung Cell Mol Physiol2001，280，6： | 1 |
| 9 | Effects of non-equi-libriUIll atmospheric pressure plasma on the heterotrophie pathways ofbacteria and on their cell morphology显示文摘 | Laroussi M Richardson J P Dobbs F C | 2002 | Appl phys lett2002，81，2： | 1 |
| 10 | Serum lipid effects of high-monounsaturated fat diet based on macadamia nuts显示文摘 | Curb J D Wergowske G Dobbs J C | 2000 | Archives of Internal Medicine2000，160，8： | 1 |
| 11 | Quantitative detection of increasing HIV type 1antibodies after seroconversion:a simple assay for detecting recent HIV infection and estimating incidence显示文摘 | J Parekh BS Kennedy MS Dobbs T | 2002 | AIDS Res Hum Retroviruses2002，18，4： | 1 |
| 12 | A structural model for regulation of NHEJ by DNA PKcs autophosphorylation显示文摘 | Dobbs T A Tainer J A Lees-Miller S P | 2010 | DNA Repair(Amst)2010，9，12： | 1 |
| 13 | Bleeding complications following percutaneous tendoachilles tenotomy in the treatment of clubfoot deformity显示文摘 | Matthew B Dobbs J Eric G | 2004 | J Pediatr Othop2004，24，4： | 1 |
| 14 | Vacuum electronic high power terahertz sources显示文摘 | Booske J H Dobbs R J Joye C D | 2011 | IEEE Trans on Terahertz Science And Tech-nology2011，1，1： | 1 |
| 15 | Performance characteristics of the immnnoglobulin G-capture BED-enzyme immunoassay,all assay to detect recent human immunodeficiency virus type l seroconversion显示文摘 | J Dobbs T Kennedy S Pau CP | 2004 | J Clin Microbiol2004，42，6： | 1 |
| 16 | Selectivities in pure and mixed supercritical fluid solvents显示文摘 | DOBBS J M JOHNSTON K P | 1987 | lnd Eng Chem Res1987，26，7： | 1 |
| 17 | A Drosophila gene encoding a visual system specific Ge molecule显示文摘 | LEE Y J DOBBS M B VERARDL M L | 1990 | Neuron1990，5，： | 1 |
| 18 | Antitumour copper (Ⅱ) salicylaldehyde benzoylhydrazone (H2sb) complexes: Physicochemical properties and the single-crystal X-ray structures of {2} and {2} and the related salicylaldehyde acetylhydrazone(H2sa) complex, ·H2O 显示文摘 | Ainscough E W Brodie A M Dobbs A J | 1998 | Inorg Chim Acta1998，267，1： | 1 |
| 19 | Differential gene expression by rat alveolar type Ⅰ and type Ⅱ cells determined by differential display-PCR显示文摘 | Mager E Vanderbilt J Dobbs L | 1999 | Am J Resp Crit Care Med1999，159，： | 1 |
| 20 | Compres- sion characteristics of carbon fibers显示文摘 | DOBB M G JOHNSON D J RARK C R | 1990 | Journal of Material Science1990，25，： | 1 |
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