|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Quantitative analysis using ELISA of vascular endothelial growth factor and basic fibroblast growth factor in human colorectal cancer,liver metastasis of colorectal cancer and hepatocellular carcinoma显示文摘TO THE EDITOR Angiogenesis consists of the sprouting of capillaries from pre-existing vessels . It is well-known that tumor growth is angiogenesis-dependent. Vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) stimulated vascular endothelial cell proliferation and are involved in the neoplastic angiogenesis of several types of tumors including those of the intestinal tract.Authors usually investigated VEGF and bFGF protein expressions using immunohistochemistry or Western blotting and VEGF and bFGF transcripts using reverse transcriptase polymerase chain reaction (RT-PCR). We recently reported in a previous issue of the World Journal of Gastroenterology that cirrhotic liver tissue levels of these two | Muriel Mathonnet Bernard Descottes Denis Valleix Francois Labrousse Véronique Truffinet Yves Denizot | 2006 | World Journal of Gastroenterology2006，12，23： | 27 |
| 2 | Platelet-activating factor in cirrhotic liver and hepatocellular carcinoma显示文摘瞄准:激活血小板的因素(PAF ) 是一个支持 inflammatory 和 angiogenic 类脂化合物调停人。这里,我们试图调查 PAF 的层次, lyso-PAF ( PAF 先锋),磷脂酶 A ( 2 )( PLA ( 2 ),产生 lyso-PAF 的酶的活动), acetylhydrolase 活动(啊哈, PAF 降级的酶)并且在硬变肝和肝细胞癌( HCC )的 PAF 受体( PAF-R )抄本。方法:有 HCC 的 29 个病人在这研究被注册。肝硬化在十四个病人是在场的,七没有肝疾病。织物 PAF 层次被血小板聚集试金调查。Lyso-PAF 在它的化学乙酰化作用以后被估计进 PAF。啊哈被降级决定[(3 ) H ]-PAF。PLA (2 ) 层次被 EIA 估计。PAF-R 抄本用 RT-PCR 被调查。结果:PAF 和 PAF-R 抄本的提高的数量(白血球类型) 1 作为与非肝脏硬化症的相比在肝脏硬化症的纸巾被发现。PAF 和 PAF-R 抄本的更高的数量(织物类型) 1 和 2 作为与非肿瘤纸巾相比在 HCC 纸巾被发现。PLA (2 ) , lyso-PAF 和啊哈层次没在肝脏硬化症的纸巾和 HCC 被改变。结论:当 PAF 的角色在肝生理学当前是未知的时,这研究在在 HCC 期间在硬变肝并且在 angiogenic 反应发现的煽动性的网络建议它的潜在的参与。 | Muriel Mathonnet Bernard Descottes Denis Valleix Véronique Truffinet Franois Labrousse Yves Denizot | 2006 | World Journal of Gastroenterology2006，12，17： | 7 |
| 3 | Contribution of functional KIR3DL1 to ankylosing spondylitis显示文摘Increasing evidence points to a role for killer immunoglobulin-like receptors(KIRs)in the development of autoimmune diseases.In particular,a positive association of KIR3DS1(activating receptor)and a negative association of KIR3DL1(inhibitory receptor)alleles with ankylosing spondylitis(AS)have been reported by several groups.However,none of the studies analyzed these associations in the context of functionality of polymorphic KIR3DL1.To better understand how the KIR3DL1/3DS1 genes determine susceptibility to AS,we analyzed the frequencies of alleles and genotypes encoding functional(KIR3DL1*F)and non-functional(KIR3DL1*004)receptors.We genotyped 83 AS patients and 107 human leukocyte antigen(HLA)-B27-positive healthy controls from the Russian Caucasian population using a two-stage sequence-specific primer PCR,which distinguishes KIR3DS1,KIR3DL1*F and KIR3DL1*004 alleles.For the patients carrying two functional KIR3DL1 alleles,those alleles were additionally genotyped to identify KIR3DL1*005 and KIR3DL1*007 alleles,which are functional but are expressed at low levels.KIR3DL1 was negatively associated with AS at the expense of KIR3DL1*F but not of KIR3DL1*004.This finding indicates that the inhibitory KIR3DL1 receptor protects against the development of AS and is not simply a passive counterpart of the segregating KIR3DS1 allele encoding the activating receptor.However,analysis of genotype frequencies indicates that the presence of KIR3DS1 is a more important factor for AS susceptibility than the absence of KIR3DL1*F.The activation of either natural killer(NK)or T cells via the KIR3DS1 receptor can be one of the critical events in AS development,while the presence of the functional KIR3DL1 receptor has a protective effect.Nevertheless,even individuals with a genotype that carried two inhibitory KIR3DL1 alleles expressed at high levels could develop AS. | Ivan V Zvyagin Ilgar Z Mamedov Olga V Britanova Dmitriy B Staroverov Evgeni L Nasonov Anna G Bochkova Anna V Chkalina Alexei A Kotlobay Dmitriy O Korostin Denis V Rebrikov Sergey Lukyanov Yuri B Lebedev Dmitriy M Chudakov | 2010 | Cellular & Molecular Immunology2010，7，6： | 5 |
| 4 | 外加应力对贝氏体相变组织形貌的影响显示文摘为揭示贝氏体相变机制及外加应力对它的影响,采用透射电镜研究了140MPa的外加拉应力对中碳低合金钢35MV7的450°C等温贝氏体相变组织形貌的影响.研究发现,由于外加应力的存在,贝氏体相变基元及其组成的铁素体条的尺寸变得非常粗大并形成多样的变态.这种尺寸的变化是由于外加应力产生额外的相变驱动力,使相变基元块可以克服更大的弹性应变能而长成更大的体积. | 苏铁健 李树奎 张朝晖 AEBY-GAUTIER E DENIS S BRIEN V | 2005 | 材料科学与工艺2005，13，3： | 3 |
| 5 | HCV ‐associated B ‐cell non‐ H odgkin lymphomas and new direct antiviral agents显示文摘 | Paul Carrier Arnaud Jaccard Jérémie Jacques Tessa Tabouret Marilyne Debette‐Gratien Julie Abraham Laura Mesturoux Pierre Marquet Sophie Alain Denis Sautereau Marie Essig Véronique Loustaud‐Ratti | 2015 | Liver Int2015，，10： | 2 |
| 6 | Metal influence on metallothionein synthesis in the hydrothermal vent mussel Ba thymodiolus thermophilus 显示文摘 | Hardivillier Y Denis F Demattei M V | 2006 | Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology2006，143，3： | 1 |
| 7 | Hepatic tumors: detection and characterization at 1-T MR imaging enhanced with AMI-25 显示文摘 | Denys A Arrive L Servois V | 1994 | Ra diology1994，193，3： | 1 |
| 8 | Role of yon Willebrand factor in tumor metastasis显示文摘 | Terraube V Marx I Denis CV | 2008 | Thromb Res2008，123，1： | 1 |
| 9 | Implicit learning deficitin children with developmental dyslexia显示文摘 | Stefano V Luigi M Deny M | 2003 | N europsychologia2003，，41： | 1 |
| 10 | High- perfor- mance Hall sensors based on III- V heterostrctures显示文摘 | Aboulhouda S Denis J | 1994 | Sensors and Actuators A1994，4142，： | 1 |
| 11 | Financial constraints, investment, and the value of cash holdings 显示文摘 | Denis D J Sibilkov V | 2010 | Review of Financial Studies2010，23，1： | 1 |
| 12 | Interval training in elderly men increases both heart rate variability and baroreflex activity显示文摘 | PICHOT V ROCHE F DENIS C | 2005 | Clin Auton Res2005，15，： | 1 |
| 13 | Finaneial Constraints, Investment, and the Value of Cash Holdings显示文摘 | Denis D J Sibilkov V | 2010 | Review of Finaneial Studies2010，，1： | 1 |
| 14 | Financial constraints, invest- ment, and the value of cash holdings 显示文摘 | Denis D J Sibilkov V | 2010 | Review of Financial Studies2010，23，： | 1 |
| 15 | Internal Ca(2 + ) release in yeast is trig- gered by hypertonic shock and mediated by a TRP channel homologue 显示文摘 | Denis V Cyert MS | 2002 | J Cell Bioi2002，156，1： | 1 |
| 16 | Helical CT assessmetnt in hilar cholangiocarcinoma: correlation with surgical and pathologic findings显示文摘 | Feydy A Vilgrain V Denys A | 1999 | AJR1999，127，1： | 1 |
| 17 | Specific leaf area and dry matter content estimate thickness in Laminar leaves显示文摘 | Denis V Eric G Arnier B | 2005 | Annals of Botany2005，96，： | 1 |
| 18 | Influence of aminosilane surface fimctionalization of rare earth hydride-forraing alloys on palladium treatment by electroless deposition and hydrogen sorption kinetics of composite materials 显示文摘 | WILLIAMS M NECHAEV A N LOTOTSKY M V YARTYS V A SOLBERG J K DENYS R V PINEDA C LI Q LINKOV V M | 2009 | Mater Chem Phys2009，115，1： | 1 |
| 19 | The choice among bank debt, non-bank private debt, and public debt: evidence from new cor- porate borrowings 显示文摘 | DENIS D J MIHOV V T | 2003 | Journal of Financial Economies2003，70，1： | 1 |
| 20 | Financial constraints, investment, and the value of cash holdings 显示文摘 | DENIS D J SIBILKOV V | 2010 | The Reviews of Financial Studies2010，23，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员