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| 1 | Computed tomography-guided percutaneous core needle biopsy in pancreatic tumor diagnosis显示文摘AIM: To evaluate the techniques, results, and complications related to computed tomography(CT)-guided percutaneous core needle biopsies of solid pancreatic lesions.METHODS: CT-guided percutaneous biopsies of solid pancreatic lesions performed at a cancer reference center between January 2012 and September 2013 were retrospectively analyzed. Biopsy material was collected with a 16-20 G Tru-Core needle(10-15 cm; Angiotech, Vancouver, CA) using a coaxial system and automatic biopsy gun. When direct access to the lesion was not possible, indirect(transgastric or transhepatic) access or hydrodissection and/or pneumodissection maneuvers were used. Characteristics of the patients, lesions, procedures, and histologic results were recorded using a standardized form. RESULTS: A total of 103 procedures included in the study were performed on patients with a mean age of 64.8 year(range: 39-94 year). The mean size of the pancreatic lesions was 45.5 mm(range: 15-195 mm). Most(75/103, 72.8%) procedures were performed via direct access, though hydrodissection and/or pneumodissection were used in 22.2%(23/103) of cases and indirect transhepatic or transgastric access was used in 4.8%(5/103) of cases. Histologic analysis was performed on all biopsies, and diagnoses were conclusive in 98.1%(101/103) of cases, confirming3.9%(4/103) of tumors were benign and 94.2%(97/103) were malignant; results were atypical in 1.9%(2/103) of cases, requiring a repeat biopsy to diagnose a neuroendocrine tumor, and surgical resection to confirm a primary adenocarcinoma. Only mild/moderate complications were observed in 9/103 patients(8.7%),and they were more commonly associated with biopsies of lesions located in the head/uncinate process(n =8), than of those located in the body/tail(n = 1) of the pancreas, but this difference was not significant.CONCLUSION: CT-guided biopsy of a pancreatic lesion is a safe procedure with a high success rate, and is an excellent option for minimally invasive diagnosis. | Chiang J Tyng Maria Fernanda A Almeida Paula NV Barbosa Almir GV Bitencourt José Augusto AG Berg Macello S Maciel Felipe JF Coimbra Luiz Henrique O Schiavon Maria Dirlei Begnami Marcos D Guimares Charles E Zurstrassen Rubens Chojniak | 2015 | World Journal of Gastroenterology2015，21，12： | 14 |
| 2 | Modeling VOCs adsorption onto activated carbon 显示文摘 | C L Chuang P C Chiang and E E Chang | 2003 | Chemosphere2003，53，1： | 1 |
| 3 | Instance Based Attribute Identification in Database Integration显示文摘 | ChuaC E H Chiang R H L Lim E P | 2003 | VLDB Journal2003，12，3： | 1 |
| 4 | Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function显示文摘 | Chiang C Litingtung Y Lee E | 1996 | Nature1996，383，6599： | 1 |
| 5 | Fault diagnosis in chemical processes using Fisher discriminant analysis,discriminant partial least squares,and principal component analysis显示文摘 | Chiang L H Russell E L Braatz R D | 2000 | Chemometrics and Intelligent Laboratory Systems2000，50，2： | 1 |
| 6 | The Role of Dbf4/Drfl-dependent ki- nase Cdc7 in DNA-damage checkpoint control显示文摘 | Tsuji T Lau E Chiang JJ | 2008 | Mol Cell2008，32，6： | 1 |
| 7 | Modeling VOCs adsorption onto activated carbon 显示文摘 | CHUANG C L CHIANG P C CHANG E E | 2003 | Chemosphere2003，53，1： | 1 |
| 8 | Effect of bromide on the formation of THMs and HAAs显示文摘 | CHANG E E LIN Y P CHIANG P C | 2001 | Chemosphere2001，43，： | 1 |
| 9 | Fault diagnosis based on Fisher discriminant analysis and support vector machines显示文摘 | Leo H Chiang Mark E Kotanchek Arthnr K Kordon | 2004 | Computers & Chemical Engineering2004，28，8： | 1 |
| 10 | Type B responseregulators of Arabidopsis play key roles in cytokinin signaling and plant de-velopment显示文摘 | ARGYROS R D MATHEWS D E CHIANG Y H | 2008 | Plant Cell2008，20，： | 1 |
| 11 | Comparisons of metal leachability for various wastes by extraction and leaching methods显示文摘 | Chang E E Chiang P C Lu P H | 2001 | Chemosphere2001，45，1： | 1 |
| 12 | Limits of medium-chain and long-chain triacylglyc- erol utilization by neonatal piglets 显示文摘 | CHIANG S H PETTIGREW J E CLARKE S D | 1990 | Journal of Ani- mal Science1990，68，6： | 1 |
| 13 | The speed of adjust- ment to information: evidence from the Chinese stock market显示文摘 | CHIANG T NELLING E TAN L | 2008 | International Review of Economics and Fi- nance2008，17，2： | 1 |
| 14 | Comparisons of metal leach ability for various wastes by extraction and leaching methods显示文摘 | Chang E E Chiang P C | 2001 | Chemosphere2001，45，： | 1 |
| 15 | A 3D FEM methodology for simulating the impact in rock-drilling hammers显示文摘 | Chiang L E Elias D A | 2008 | International Journal of Rock Mechanics and Mining Sciences2008，45，5： | 1 |
| 16 | Cyclopia and defective axial patterning in mice lacking sonic hedgehog gene function显示文摘 | Litingtung Y Lee E | 1996 | Nature1996，383，6599： | 1 |
| 17 | Effects of surface characteristics of activated carbons on VOC adsorption显示文摘 | CHIANG Y C CHIANG P C CHANG E E | 2001 | J Environ Eng2001，127，1： | 1 |
| 18 | Fault diagnosis based on Fisher discriminant analysis and support vector machines显示文摘 | Chiang L H Kotanchek M E Kordon A K | 2004 | Computers & Chemical Engineering2004，28，8： | 1 |
| 19 | Fault Diagnosis Based on Fisher Discriminant Analysis and Support Vector Machines显示文摘 | Chiang Leo H Kotanchek Mark E Kordon Arthur K | 2004 | Computers & Chemical Engineering2004，28，8： | 1 |
| 20 | Effects of polyelectrolytes on reduction of model compounds via coagulation 显示文摘 | Chang E Chiang P C Tang W Y | 2005 | Ehemosphere2005，58，8： | 1 |
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