|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Type 2 diabetes mellitus and CA 19-9 levels显示文摘AIM:To prospectively investigate serum CA 19-9 levels in type 2 diabetic patients in comparison with age-and gender-matched control subjects. METHODS:We recorded duration of diabetes and examined fasting glucose levels,HbA1c levels and serum CA 19-9 levels in 76 type 2 diabetic patients and 76 controls.Abdominal CT was performed in order to eliminate abdominal malignancy in the diabetic and control groups. RESULTS:The average CA 19-9 level was 46.0±22.4 U/mL for diabetic patients whereas it was 9.97±7.1 U/mL for the control group(P<0.001).Regression analysis showed a positive correlation between diabetes and CA 19-9 independent from age,gender,glucose level and HbA1c level(t=8.8,P<001).Two of the diabetic patients were excluded from the study because of abdominal malignancy shown by CT at the initial evaluation.For all patients,abdominal CT showed no pancreatic abnormalities. CONCLUSION:CA 19-9 is a tumor-associated antigen, which is elevated in pancreatic,upper gastrointestinal tract,ovarian hepatocellular,and colorectal cancers,as well as in inflammatory conditions of the hepatobiliary system,biliary obstruction and in thyroid diseases. Diabetes has been claimed to be a risk factor for pancreatic cancer,which is increasing its incidence and has one of the lowest survival rates of all cancers.CA 19-9 is used in the diagnosis of pancreatic cancer but is also a marker of pancreatic tissue damage that might be caused by diabetes.We propose that a higher cut- off value of CA 19-9 should be used in diabetics to differentiate benign and malignant pancreatic disease, and subtle elevations of CA 19-9 in diabetics should be considered as the indication of exocrine pancreatic dysfunction. | Oya Uygur-Bayramicli Resat Dabak Ekrem Orbay Can Dolapclo■lu Mehmet Sargin Gamze Kilico■lu Yüksel Güleryüzlü Alpaslan Mayada■li | 2007 | World Journal of Gastroenterology2007，13，40： | 63 |
| 2 | Room and Low Temperature Luminescence Properties of CaSO4: Dy, Tm Codoped with Li 显示文摘 | Can N Karali T Wang Y | 2009 | Physics Procedia2009，2，： | 1 |
| 3 | GInK, a PII-homologue: structure reveals ATP binding site and indicates how the T-loops may be involved in molecular recognition显示文摘 | Xu Y Cheah E Can' PD | 1998 | J Mol Biol1998，282，1： | 1 |
| 4 | Reperfusion induced oxid-ative /nitrative injury to neurovascular unit afterfocal cerebralischemia 显示文摘 | Gursoy20zdemir Y Can A Dalkara T | 2004 | Stroke2004，35，： | 1 |
| 5 | Reperfusioninduced oxidative/nitrative injury to neurovascular unit after focal cerebral ischemia 显示文摘 | Gursoy-Ozdemir Y Can A Dalkara T | 2004 | Stroke2004，35，6： | 1 |
| 6 | Improved discharge capacity and suppressed surface passivation of zinc anode in dilute alkaline solution using surfactant additives显示文摘 | Yang H X Can Y L Ai X N | 2004 | J Power Sources2004，128，1： | 1 |
| 7 | Unraveling the regulatory network of the MADS box transcfipfion factor KIN in fruit ripening显示文摘 | Qin G Wang Y Can B | 2012 | The Plant Journal2012，70，2： | 1 |
| 8 | Coaxial,microcoaxial,and biaxial nicroincision cataract surgery:prospective comparative study显示文摘 | Can I Takmaz T Yildiz Y etal | 2010 | J Cataract Refract Surg2010，36，： | 1 |
| 9 | Clinical features of the initial eases of 2009 pandemic influenza A (H1N1)vires infectinn in China 显示文摘 | Can B Li XW Man Y el al | 2009 | N Engl J Med2009，361，26： | 1 |
| 10 | Prognostic value of matrix metalloproteinases (MMP-2 and MMP-9) in patients with lymph nodenega- tire breast carci-noma 显示文摘 | Li HC Can DC Liu Y | 2004 | Breast Cancer Res Treat2004，88，1： | 1 |
| 11 | Polymorphisms in immtme/inflammatory cytokine genes are related to Parkinson' s disease withcognitive impairment in the Han Chinese population显示文摘 | Nie K Zhang Y Can R | 2013 | Neurosei Lett2013，541，： | 1 |
| 12 | Elevated serum uric acid in nondiabetic people mark pro-inflammatory state and HDL dysfunction and independently predicts coronary disease显示文摘 | Altan Onat Günay Can Ender ?rnek Servet Altay Murat Yüksel Evin Ademo?lu | 2013 | Clinical Rheumatology2013，，： | 1 |
| 13 | Attenuation of Streptococcus suis virulence by the alteration of bacterial surface architecture显示文摘 | Feng Y Can M Shi J | 2012 | Science Report2012，2，： | 1 |
| 14 | Biodiesel production using cation-exchange resin as heterogeneous catalyst显示文摘 | Feng Y H He B Q Can Y H | 2010 | BioresourceTechnology2010，101，： | 1 |
| 15 | Acoustic Emis- sion During Fatigue Crack Propagation in a Micro-al- loyed Steel and Welds显示文摘 | HanZ Y Luo H Y Can J W | 2011 | Materials Science & Engi- neering A2011，528，77： | 1 |
| 16 | Coaxial,microcoaxial,andbiaxial microincision cataract surgery prospective compar-ative study显示文摘 | Can I Takmaz T1Yildiz Y | 2010 | J Cataract Refract Surg2010，36，5： | 1 |
| 17 | Conxial, microcoaxial, and biaxial microincision cataract surgery : pro - Spective comparatine study 显示文摘 | Can I Takmax T Yildiz Y | 2010 | J Cataract Refract Surg2010，36，5： | 1 |
| 18 | Detecion and location of Heli--cobacter pylori in human gastric carcinomas显示文摘 | Tang Y L Can R L Dong B H | 2005 | World J Gastroenterol2005，11，9： | 1 |
| 19 | The in vivo and in vitro effects of chicken interferon α on infectious bursal disease virus and Newcastle disease virus infection显示文摘 | Mo C W Can Y C Lim B L | 2001 | Avian Diseases2001，45，： | 1 |
| 20 | Tachycardia-induced car- diomyopathy in patients with idiopathic ventricular ar- rhythmias: the incidence, clinical and electrophysiologic characteristics, and the predictors 显示文摘 | Can H Cem U Oguz Y | 2011 | J Cardiovasc Elect- rophysiol2011，22，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员