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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Gonadotropin releasing hormone and conception of Holstein 显示文摘 | Stevenson J S Schmidt M K Call E P | 1981 | J Dairy Sci1981，67，： | 2 |
| 3 | Electrochemical properties and corrosion protection of organosilane self-assem-bled monolayers on aluminum 2024-T3 显示文摘 | Hintze P E Calle L M | 2006 | Electro- chimica Acta2006，51，8： | 1 |
| 4 | Analytical methods for the determination of acrylamide in the food products:a review显示文摘 | Beatriz de la Calle M Anklam E | 2003 | Food Additives and Contaminants2003，20，10： | 1 |
| 5 | High Surface Area Stainless Steel Brushes as Cathodes in Microbial Electrolysis Cells 显示文摘 | Call D F Merrill M D Logan B E | 2009 | Envi-ron Sci Technol2009，43，6： | 1 |
| 6 | A novel role of the hedgehog pathway in lens regeneration显示文摘 | Tsonis P A Vergara M N Spence J R Madhavan M Kramer E L Call M K | 2004 | Dev Biol2004，267，： | 1 |
| 7 | High surface area stainless steel brushes as cathodes in microbial electrolysis cells显示文摘 | Call D F Merrill M D Logan B E | 2009 | Environmental Scienee andTechnology2009，43，： | 1 |
| 8 | 查看详情显示文摘 | Thun M J Altekruse S F Namboodiri M M Calle E E | | 0，，： | 1 |
| 9 | The Structure of Individual Differences in the Cognitive Abilities of Children and Chimpanzees显示文摘 | Herrmann E Herndndez- Lloreda M V Call J | 2009 | Psychological Science2009，，1： | 1 |
| 10 | Semicarbazide: occurrence in food products and state-of-the-art in analytical methods used for its determination显示文摘 | de la CALLE M B ANKLAM E | 2005 | Anal Bioanal Chem2005，382，4： | 1 |
| 11 | Estrogen replacement therapy and risk of fatal colon cancer in a prospective cohort of post- menopausal women显示文摘 | CALLE E E MIRACLE-MCMAHILL H L THUN M J | 1995 | J Natl Cancer Inst1995，87，7： | 1 |
| 12 | 显示文摘 | Calle M Garcia C Lozano A E | 2013 | Journal of Membrane Science2013，434，： | 1 |
| 13 | Aspirin use and risk of fatal cancer显示文摘 | THUN M J NAMBOODIRE M M CALLE E E | 1993 | Cancer Res1993，53，6： | 1 |
| 14 | Adorption ofphenanthrene on activated carbons: breakthrough curve modeling 显示文摘 | Murillo R Garc?a T Aylón E Callén M S | 2004 | Carbon2004，42，： | 1 |
| 15 | Ce-ZSM-5 catalysts for the selective catalytic reduction of NOx in stationary diesel exhaust gas显示文摘 | Van KOOTEN W E J LIANG B KRIJNSEN H C OUDSHOORN O L CALLS H P A Van den BLEEK C M | 1999 | Appl Catal B1999，21，3： | 1 |
| 16 | Lung cancer,cardiopulmonary mortality and long_term exposure to fine particulate air pollution显示文摘 | Pope C A Burnett R T Thun M J Calle E E Krewski D Ito K Thurston G D | | 0，，： | 1 |
| 17 | The T cell receptor: critical role of the membrane environment in receptor assembly and function 显示文摘 | CALL M E WUCHERPFENNING K W | 2005 | Annu Rev Immunol2005，23，： | 1 |
| 18 | Stoichiometry of the T-cell receptor-CD3 complex and key intermediates assembled in the endoplasmic reticulum 显示文摘 | CALL M E PYRDOL J WUCHERPFENNING K W | 2004 | EMBO J2004，23，12： | 1 |
| 19 | Real-time detection of chlorpyrifos at part per trillion levels in ground, surface and drinking water samples by a portable surface plasmon resonance immunosensor显示文摘 | Mauriz E Calle A Lechuga L M | 2006 | Analytica Chimica Acta2006，561，： | 1 |
| 20 | Analytical methods for the determination of acrylamide in the food products: a review显示文摘 | Wenzel T Beatriz de la Calle M Anklam E | 2003 | Food Additives and Contaminants2003，20，10： | 1 |
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