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| 1 | Effect of propranolol on the splanchnic and peripheral renin angiotensin system in cirrhotic patients显示文摘AIM:To evaluate the effect of β-blockade on angiotensins in the splanchnic and peripheral circulation of cirrhotic patients and also to compare hemodynamic parameters during liver transplantation according to propranolol pre-treatment or not. METHODS:Patients were allocated into two groups:outpatients with advanced liver disease(LD) and during liver transplantation(LT). Both groups were subdivided according to treatment with propranolol or not. Plasma was collected through peripheral venipuncture to determine plasma renin activity(PRA),Angiotensin(Ang) Ⅰ,Ang Ⅱ,and Ang-(1-7) levels by radioimmunoassay in LD group. During liver transplantation,hemodynamic parameters were determined and blood samples were obtained from the portal vein to measure renin angiotensin system(RAS) components.RESULTS:PRA,Ang Ⅰ,Ang Ⅱ and Ang-(1-7) were signifi cantly lower in the portal vein and periphery in all subgroups treated with propranolol as compared to non-treated. The relationships between Ang-(1-7) and Ang Ⅰ levels and between Ang Ⅱ and Ang Ⅰ were significantly increased in LD group receiving propranolol. The ratio between Ang-(1-7) and Ang Ⅱ remained unchanged in splanchnic and peripheral circulation in patients under β-blockade,whereas the relationship between Ang Ⅱ and Ang Ⅰ was significantly increased in splanchnic circulation of LT patients treated with propranolol. During liver transplantation,cardiac output and index as well systemic vascular resistance and index were reduced in propranolol-treated subgroup. CONCLUSION:In LD group,propranolol treatment reduced RAS mediators,but did not change the ratio between Ang-(1-7) and Ang Ⅱ in splanchnic and peripheral circulation. Furthermore,the modification of hemodynamic parameters in propranolol treated patients was not associated with changes in the angiotensin ratio. | Walkíria Wingester Vilas-Boas Antnio Ribeiro-Oliveira Jr Renata da Cunha Ribeiro Renata Lúcia Pereira Vieira Jerusa Almeida Ana Paula Nadu Ana Cristina Sim■es e Silva Robson Augusto Souza Santos | 2008 | World Journal of Gastroenterology2008，14，44： | 2 |
| 2 | Feeding behaviour of fast- and slow-growing stains of rainbow trout,Oncorhynchus mykiss (Walbaum) during first feeding 显示文摘 | Valente L M P Saglio P Cunha L M | 2001 | Aquaculture Research2001，32，： | 1 |
| 3 | The nonsubsampled Contourlet transform: theory, design, and applications 显示文摘 | Cunha A L Zhou J Do M N | 2006 | IEEE Transactions on Image Process2006，15，10： | 1 |
| 4 | 查看详情显示文摘 | Wang X F da Cunha Lima I C Lei X L | | 0，，： | 1 |
| 5 | Effect of milk fatand total solids concentration on the kinetics of moistureuptake by ready-to-eat breakfast cereal 显示文摘 | Machado M F Oliveira FAR Cunha L M | 1999 | InternationalJournal of Food Science and Technology1999，34，1： | 1 |
| 6 | The NonSubsampled Contourlet Transform: Theory, design, and applications 显示文摘 | Cunha A L Zhou J and Do M N | 2006 | IEEE Transactions on Image Processing2006，15，10： | 1 |
| 7 | The nonsub-sampled contourlet transform:theory,design and applica-tions显示文摘 | Da Cunha A L Zhou Jiangping Do M N | 2006 | IEEE Trans on Image Proecess2006，15，10： | 1 |
| 8 | Insulin in W/O/W multiple emulsions:biological activity after oral administration in normal and diabetic rats显示文摘 | Cunha A S Grossiord J L Puisieux F | 1997 | J Microencapsulation1997，14，3： | 1 |
| 9 | Insulin in W/O/W multiple emulsions: biological activity after administration in normal and diabetic rats 显示文摘 | Silva Cunha A Grossiord J L Puiseux F | 1997 | J Mierueneapsulatiun1997，14，： | 1 |
| 10 | The nonsubsampledcontourlet transform : theory,design,and applica-tions 显示文摘 | Cunha A L Zhou J Do M N | 2006 | IEEE Transactions on Image Process-ing2006，15，10： | 1 |
| 11 | Removal of aromatics from multi-component organic mixtures bypervaporation using polyurethane membranes: experimenttal and modeling显示文摘 | Cunha V S Paredes M L L Nobrega R | 2002 | J Membr Sci2002，206，： | 1 |
| 12 | The effect of the glucono-8-1actone/caseinate ratio on sodium caseinate gelation显示文摘 | BRAGA A L M MENOSSI M CUNHA R L | 2006 | International Dairy Journal2006，16，5： | 1 |
| 13 | Contraction stress and physical properties development of a resin- based composite irradiated using modulated curing meth- ods at two C-factor levels 显示文摘 | Cunha L G Alonso R C Pfeifer C S | 2008 | Dent Mater2008，24，3： | 1 |
| 14 | The nonsubsampled contourlet transform:Theory,design and applications显示文摘 | CUNHA A L da ZHOU J DO M N | 2006 | IEEE Trans Image Process2006，15，10： | 1 |
| 15 | The Nonsubsampled Contourlet Transform:Theory,Design,and Applications显示文摘 | Arthur L da Cunha Jianping Zhou Minh N Do | 2006 | IEEE Transactions on Image Processing2006，15，10： | 1 |
| 16 | The nonsubsampled contourlet transform:Theory,design,and applications显示文摘 | CUNHA A L ZHOU J DO M N | 2006 | IEEE Transactions on Image Processing2006，15，30： | 1 |
| 17 | Microstructure of CrN coatings produced by PVD techniques显示文摘 | Cunha L Andritschky M Pischow K | 1999 | Thin Solid Films1999，，3： | 1 |
| 18 | The nonsubsampledcontourlet transform:theory,design and applications显示文摘 | CUNHA A L ZHOU J P DO M N | 2006 | IEEE Transactions on Image Processing2006，15，10： | 1 |
| 19 | The nonsubsampled Contour-let transform:theory,design,and applications 显示文摘 | Da Cunha A L Zhou Jianpin Do M N | 2006 | IEEE TransactionsImage on Processing2006，15，10： | 1 |
| 20 | Involvement of resident macrophages and mast cells in the writhing nociceptive response induced by zymosan and acetic acid in mice显示文摘 | Ronaldo A Ribeiro Mariana L Vale Sara M Thomazzi Adriana B.P Paschoalato Steve Poole Sergio H Ferreira Fernando Q Cunha | 2000 | European Journal of Pharmacology2000，，1： | 1 |
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