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118篇 您的检索式:作者名="COMHAIR"
    题名 作者 年代 出处 被引量
1烟酰胺磷酸核糖基转移酶促进肺血管重塑,是肺动脉高压的治疗靶点显示文摘肺动脉高压(pulmonary arterial hypertension,PAH)是一种严重的进行性疾病,其标志之一是肺血管重塑。烟酰胺磷酸核糖基转移酶(nicotinamide phosphoribosyl transferase,NAMPT)是调节细胞内烟酰胺腺嘌呤二核苷酸水平、细胞氧化还原状态,调节组蛋白脱乙酰酶,促进细胞增殖和抑制凋亡的一种细胞酶。研究人员假设NAMPT可促进肺血管重塑,Chen J Sysol JR Singla S Zhao S Yamamura A Valdez-Jasso D Abbasi T Shioura KM Sahni S Reddy V Sridhar A Gao H Torres J Camp SM Tang H Ye SQ Comhair S Dweik R Hassoun P Yuan JX Garcia JG Machado RF 刘莉 叶鹏 2017中华高血压杂志2017,25,2:10
2血管内皮生长因子受体3通过β抑制蛋白1调节内皮功能显示文摘受体信号转导对于维持血管内皮功能至关重要,其在动脉粥样硬化和肺动脉高压(pulmonary arterial hypertension,PAH)等血管疾病中出现失调。内皮功能相关受体信号包括血管内皮生长因子(vascular endothelial growth factor,VEGF)受体(VEGFR)和G蛋白耦联受体(G protein-coupled receptor,GPCR),激活特异的细胞内信号通路和反应。刘青 叶鹏 Ma Z Yu YR Badea CT Kovacs JJ Xiong X Comhair S Piantadosi CA Rajagopal S 2019中华高血压杂志2019,27,1:5
3Reassessment of the accuracy of traditional sperm characteristics and adenosine triphosphate (ATP) in estimating the fertilizing potential of human semen in vivo显示文摘Comhaire F H Vermeulen L Schoonjans F 1987Int J Androl1987,,10:2
4Adenosine triphosphate in human semen: a quantitative estimate of fertilizing potential显示文摘Comhaire F H Vermeulen L Ghedira K 1983Fertil Steril1983,40,:2
5Antioxidant responses to oxidant-mediated lung diseases显示文摘 Comhair Serpil CE 2002Am J Physiol Lung Cell Mol Physiol2002,283,2:1
6Differential expression of manganese superoxide dismutase and catalase in lungcancer显示文摘Chung-man Ho J Zheng S Comhair SA 2001Cancer Res2001,61,23:1
7Abnormalities in nitric oxide and its derivatives in lung cancer 显示文摘Masri FA Comhair SAA Koeck T 2005Am J Respir Crit Care Med2005,172,5:1
8Super oxide dismutase in activation in pathophysiology of asthmatic airway remodeling and reactivity显示文摘Comhair S A Xu W Ghosh S 2005Am J Pathol2005,166,3:1
9Hyperproliferative apoptosisresistant endothelial oells in idiopathic pulmonary arterial hypertension显示文摘Masri FA Xu W Comhair SA 2007Am J Physiol Lung Cell Mol Physiol2007,293,:1
10Hyperproliferative apoptosisresistant endothelial cells in idiopathic pulmonary arterial hypertension显示文摘Masri FA Xu W Comhair SA 2007Am J Physiol Lung Cell Mol Physiol2007,293,3:1
11Differential expression of manganese superoxide dismutase and catalase in lung cancer 显示文摘Chung man Ho J Zheng S Comhair SA 2001Cancer Res2001,61,23:1
12Correlation of sustemic supero-xide dismutase deficiency to airflow obstruction in asthma显示文摘Comhair S A A Ricci K S Arroliga M 2005Respir Crie Care Med2005,172,3:1
13Variant forms of DNA polymerase beta in primary lung carcinomas显示文摘Bhattacharyya N Chen HC Comhair S 1999DNA Cell Biol1999,18,7:1
14Urinary bmmotyrosine measures asthma control and predicts asthma exacerbations in children显示文摘Wedes SH Wu W Comhair SA 2011J pediatrics2011,159,2:1
15Abnormalities in nitric oxide and its derivatives in lung cancer显示文摘Masri F A Comhair S A A Koeck T 2005Am J Respir Crit Care Med2005,172,5:1
16Complement C3 deficiency attenuates chronic hypoxia-induced pulmonary hypertension in mice 显示文摘Bauer EM Zheng I-I Comhair S 2011PLoS One2011,6,28:1
17Preventing diseases of the prostate in the elderly using hormones and nutriceuticals显示文摘Comhaire F Mahmoud A 2004Aging Male2004,7,2:1
18Molecular mechanisms of increased nitric oxide (NO) in asthma: evidence for transcriptional and post-translational regulation of NO synthesis 显示文摘Guo FH Comhair SA Zheng S 2000J Immunol2000,164,:1
19NO chemical events in the human airway during the immediate and late antigeninduced asthmatic response显示文摘Dweik RA Comhair SA Gaston B 0,,:1
20Molecular mechanisms of increased nitric oxid ( NO ) in asthma: evidence for transcriptional and post-translational regulation of NO synthesis 显示文摘GUO F H COMHAIR SA ZHENG S 2000J Immunol2000,164,11:1
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