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| 1 | 评估清晨或夜晚服用降压药对24h动态血压的影响:清晨或夜间服用降压药的希腊英国联合研究显示文摘观察数据显示,临床血压水平与随后的主要不良心血管事件之间存在强烈的线性关系。然而,动态血压监测显示,夜间血压水平比24h或白天血压水平更能预测主要的不良心血管事件。此外,夜间与白天的血压比值和杓型状态也是心血管结局的重要独立预测因素。这些发现可能对抗高血压药物的最佳给药时间有影响,一些研究表明,夜晚服用降压药可能较白天服药减少心血管事件。 | Poulter NR Savopoulos C Anjum A Apostolopoulou M Chapman N Cross M Falaschetti E Fotiadis S James RM Kanellos I Szigeti M Thom S Sever P Thompson D Hatzitolios AI 赵狄 练桂丽 | 2018 | 中华高血压杂志2018，26，10： | 7 |
| 2 | Current surgical treatment strategies for hepatocellular carcinoma in North America显示文摘Hepatocellular carcinoma(HCC) is an aggressive tumor that often occurs in the setting of chronic liver disease.Many patients do not initially manifest any symptoms of HCC and present late when cure with surgical resection or transplantation is no longer possible.For this reason,patients at high risk for developing HCC are subjected to frequent screening processes.The surgical management of HCC is complex and requires an inter-disciplinary approach.Hepatic resection is the treatment of choice for HCC in patients without cirrhosis and is indicated in some patients with early cirrhosis(Child-Pugh A).Liver transplantation has emerged in the past decade as the standard of care for patients with cirrhosis and HCC meeting Milan criteria and in select patients with HCC beyond Milan criteria.Loco-regional therapy with transarterial chemoembolization,transarterial embolization,radiofrequency ablation and other similar local treatments can be used as neo-adjuvant therapy to downstage HCC to within Milan criteria or as a bridge to transplantation in patients on transplant wait list. | Adeel S Khan Kathryn J Fowler William C Chapman | 2014 | World Journal of Gastroenterology2014，20，41： | 3 |
| 3 | Global Wheat Head Detection 2021:An Improved Dataset for Benchmarking Wheat Head Detection Methods显示文摘The Global Wheat Head Detection(GWHD)dataset was created in 2020 and has assembled 193,634 labelled wheat heads from 4700 RGB images acquired from various acquisition platforms and 7 countries/institutions.With an associated competition hosted in Kaggle,GWHD_2020 has successfully attracted attention from both the computer vision and agricultural science communities.From this first experience,a few avenues for improvements have been identified regarding data size,head diversity,and label reliability.To address these issues,the 2020 dataset has been reexamined,relabeled,and complemented by adding 1722 images from 5 additional countries,allowing for 81,553 additional wheat heads.We now release in 2021 a new version of the Global Wheat Head Detection dataset,which is bigger,more diverse,and less noisy than the GWHD_2020 version. | Etienne David Mario Serouart Daniel Smith Simon Madec Kaaviya Velumani Shouyang Liu Xu Wang Francisco Pinto Shahameh Shafiee Izzat SATahir Hisashi Tsujimoto Shuhei Nasuda Bangyou Zheng Norbert Kirchgessner Helge Aasen Andreas Hund Pouria Sadhegi-Tehran Koichi Nagasawa Goro Ishikawa Sébastien Dandrifosse Alexis Carlier Benjamin Dumont Benoit Mercatoris Byron Evers Ken Kuroki Haozhou Wang Masanori Ishii Minhajul ABadhon Curtis Pozniak David Shaner LeBauer Morten Lillemo Jesse Poland Scott Chapman Benoit de Solan Frédéric Baret Ian Stavness Wei Guo | 2021 | Plant Phenomics2021，3，1： | 2 |
| 4 | Quartz isolation from rocks, sediments and soils for determination of oxygen isotopes composition显示文摘 | Syers J K Chapman S L Jackson M L | 1968 | Geochimica et Cosmochimica Acta1968，32，： | 2 |
| 5 | 中国宣威家庭炉灶改造与慢性阻塞性肺病的风险——回顾性队列研究显示文摘目的 验证中国宣威县家庭燃煤炉的改造对慢性阻塞性肺病(COPD)发病率的影响。设计方法回顾性队列研究(随访时问1976至1992年),比较有烟囱组和无烟囱组COPD发病率的差异。研究对象 20453名参与者出生在没有安装排烟系统的家庭中,其中16606人(81.2%)后来家中的燃煤炉安装了烟囱。干预 在既往没有安装排风系统的家庭中安装烟囱。结果 给燃煤炉加装烟囱与COPD的发病率降低显著相关。与家中没有安装烟囱的参与者相比,Cox模型计算的男性相对危险度(RR)为0.58(95%可信区问0.49~0.70,P〈0.001);女性相对危险度为0.75(95%可信区间0.62~0.92,P=0.005)。Cox模型的设定不同,计算出的相对危险度也是不同的。改炉改灶的年限越长,COPD的相对危险度越低。无论男性和女性,改灶后10年内COPD发病危险陛下降都非常明确。结论 宣威居民COPD的发病率随着家庭燃煤炉改造后年限增加而显著降低。 | Robert S Chapman 何兴舟 Aaron E Blair 蓝青 许军 | 2006 | 英国医学杂志中文版2006，9，6： | 2 |
| 6 | X-ray focusing using microchannel plates I theory显示文摘 | Chapman H N Nugent K A Wilkins S W | 1993 | Appl Opt1993，32，： | 2 |
| 7 | Seasonal growth in Laminaria longicruris: Relations with dissolved inorganic nutrients and internal reserves of nitrogen显示文摘 | CHAPMAN A R O CRAIGIE J S | 1977 | Mar Biol (Berlin)1977，40，： | 2 |
| 8 | Hemodynamic response to pumpless extracorporeal membrane oxygenation 显示文摘 | Chapman J Adams M Alexander S | 1990 | J Thorac Cardiovasc Surg1990，99，4： | 1 |
| 9 | Removal of the fibrillar network surrounding Cichorium somatic embryos using cytoskeleton inhibitors: analysis of protein components显示文摘 | Chapman A Helleboid S Blervacq A S | 2000 | Plant Science2000，150，1： | 1 |
| 10 | Drug Evaluations Using Neuronal Networks Cultured on Microelectrode Arrays显示文摘 | Morefield S I Keefer E W Chapman K D | 2000 | Biosensors & Bioelectronics2000，15，： | 1 |
| 11 | DNA binding- dependent and - independent functions of the Hand2 transcription factor during mouse embryogenesis显示文摘 | LIU N BARBOSA A C CHAPMAN S L | 2009 | Development2009，136，6： | 1 |
| 12 | Narrative content as described by indi-viduals with Down syndrome and typically developing chil-dren 显示文摘 | Miles S Chapman RS | 2002 | J Speech Lang Hear Res2002，45，1： | 1 |
| 13 | Coal use,stove improvement,and adult pneumonia mortality in Xuanwei,China :a retrospective cohort study显示文摘 | SHEN Min CHAPMAN R S VERMEULEN R | 2009 | Environmental HealthPerspectives2009，117，2： | 1 |
| 14 | Thermal gradients in the continental crust显示文摘 | Chapman D S | 1986 | Geol Soc Spec Publ1986，24，1： | 1 |
| 15 | Thermal histories and hydrocarbon generation: Example from Utah-Wyoming thrust belt 显示文摘 | Deming D Chapman D S | 1989 | AAPG Bulletin1989，73，12： | 1 |
| 16 | Surgical treatment of hepatocellular carcinoma: expert consensus statement显示文摘 | Jarnagin W Chapman WC Curley S | 2010 | HPB (Oxford)2010，12，5： | 1 |
| 17 | Mutational analysis of the coat protein gene of potato virus X:effects on viron morphology and viral pathogenicity显示文摘 | HILLS G WATTS J | 1992 | Virology1992，191，： | 1 |
| 18 | How to investigate and analyse clinical incidengts:Clinical risk unit and association of litigation and risk management protocol显示文摘 | Vincent C Taylor-Adams S Jane Chapman E | 2000 | British Medical Journal2000，32，5： | 1 |
| 19 | Derivation of a microstruc-tural poroelastic model显示文摘 | Chapman M Zatsepin S V Crampin S | 2002 | Geophysical Journal International2002，151，： | 1 |
| 20 | Stx2-Specific Human Monoclonal Antibodies Protect Mice against Lethal Infection with Escherichia coli Expressing Stx2 Variants显示文摘 | Sheoran A S Chapman S Singh P | 2003 | Infect Immun2003，71，： | 1 |
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