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| 1 | Physical exercise in the prevention and treatment of Alzheimer’s disease显示文摘Dementia is one of the greatest global challenges for health and social care in the 21st century.Alzheimer’s disease(AD),the most common type of dementia,is by no means an inevitable consequence of growing old.Several lifestyle factors may increase,or reduce,an individual’s risk of developing AD.Much has been written over the ages about the benefits of exercise and physical activity.Among the risk factors associated with AD is a low level of physical activity.The relationship between physical and mental health was established several years ago.In this review,we discuss the role of exercise(aerobic and resistance)training as a therapeutic strategy for the treatment and prevention of AD.Older adults who exercise are more likely to maintain cognition.We address the main protective mechanism on brain function modulated by physical exercise by examining both human and animal studies.We will pay especial attention to the potential role of exercise in the modulation of amyloid b turnover,inflammation,synthesis and release of neurotrophins,and improvements in cerebral blood flow.Promoting changes in lifestyle in presymptomatic and predementia disease stages may have the potential for delaying one-third of dementias worldwide.Multimodal interventions that include the adoption of an active lifestyle should be recommended for older populations. | Adrian De la Rosa Gloria Olaso-Gonzalez Coralie Arc-Chagnaud Fernando Millan Andrea Salvador-Pascual Consolacion Garcıa-Lucerga Cristina Blasco-Lafarga Esther Garcia-Dominguez Aitor Carretero Angela G.Correas Jose Vina Mari Carmen Gomez-Cabrera | 2020 | Journal of Sport and Health Science2020，9，5： | 32 |
| 2 | Role of videocapsule endoscopy for gastrointestinal bleeding显示文摘Obscure gastrointestinal bleeding (OGIB) is defi ned as bleeding of an unknown origin that persists or recurs after negative initial upper and lower endoscopies. Several techniques, such as endoscopy, arteriography, scintigraphy and barium radiology are helpful for recognizing the bleeding source; nevertheless, in about 5%-10% of cases the bleeding lesion cannot be determined. The development of videocapsule endoscopy (VCE) has permitted a direct visualization of the small intestine mucosa. We will analyze those techniques in more detail. The diagnostic yield of CE for OGIB varies from 38% to 93%, being in the higher range in those cases with obscure-overt bleeding. | Cristina Carretero Ignacio Fernandez-Urien Maite Betes Miguel Muoz-Navas | 2008 | World Journal of Gastroenterology2008，14，34： | 11 |
| 3 | Intestinal preparation prior to capsule endoscopy administration显示文摘In order to have an adequate view of the whole small intestine during capsule endoscopy, the preparation recommended consists of a clear liquid diet and an overnight fast. However, visualization of the small bowel during video capsule endoscopy can be impaired by intestinal contents. To improve mucosal visualization, some authors have evaluated different regimens of preparation. There is no consensus about the necessity of intestinal preparation for capsule endoscopy and it should be interesting to develop adequate guidelines to improve its efficacy and tolerability. Moreover, the effect of preparation type (purgative) on intestinal transit time is not clear. Since a bowel preparation cannot defini-tively improve its visibility (and theoretically the yield of the test), it is not routinely recommended. | Vicente Pons Beltrán Cristina Carretero Begoa Gonzalez-Suárez Iaqui Fernández-Urien Miguel Muoz-Navas | 2008 | World Journal of Gastroenterology2008，14，37： | 5 |
| 4 | Colon capsule endoscopy显示文摘Wireless capsule endoscopy has become the first imaging tool for small bowel examination. Recently, new capsule endoscopy applications have been developed, such as esophageal capsule endoscopy and colon capsule endoscopy. Clinical trials results have shown that colon capsule endoscopy is feasible, accurate and safe in patients suffering from colonic diseases. It could be a good alternative in patients refusing conventional colonoscopy or when it is contraindicated. Upcoming studies are needed to demonstrate its utility for colon cancer screening and other indications such us ulcerative colitis. Comparative studies including both conventional and virtual colonoscopy are also required. | Ignacio Fernandez-Urien Cristina Carretero Ana Borda Miguel Muoz-Navas | 2008 | World Journal of Gastroenterology2008，14，34： | 4 |
| 5 | Esophageal capsule endoscopy显示文摘Capsule endoscopy is now considered as the first imaging tool for small bowel examination. Recently, new capsule endoscopy applications have been developed, such as esophageal capsule endoscopy and colon capsule endoscopy. Esophageal capsule endoscopy in patients with suspected esophageal disorders is feasible and safe, and could be also an alternative procedure in those patients refusing upper endoscopy. Although large-scale studies are needed to confirm its utility in GERD and cirrhotic patients, current results are encouraging and open a new era in esophageal examination. | Ignacio Fernandez-Urien Cristina Carretero Raul Armendariz Miguel Muoz-Navas | 2008 | World Journal of Gastroenterology2008，14，34： | 3 |
| 6 | Long-term follow-up study of gastroduodenal lesions after radioembolization of hepatic tumors显示文摘AIM:To evaluate the long-term natural history of the gastroduodenal lesions secondary to extrahepatic embolization with Ytrium 90(90 Y) spheres.METHODS:From September 2003 to January 2012,379 procedures of liver radioembolization(RE) using resin microspheres loaded with 90 Y were performed in our center.We have retrospectively compiled the data from 379 RE procedures performed in our center.We report a comprehensive clinical,analytical,endoscopic and histologic long-term follow-up of a series of patients who developed gastroduodenal lesions after the treatment.RESULTS:Six patients(1.5%) developed gastrointestinal symptoms and had gastrointestinal lesions as shown by upper endoscopy in the next 12 wk after RE.The mean time between RE and the appearance of symptoms was 5 wk.Only one patient required endoscopic and surgical treatment.The incidence of gastrointestinal ulcerations was 3.75%(3/80) when only planar images were used for the pre-treatment evaluation.It was reduced to 1%(3/299) when singlephoton emission computed tomography(SPECT) images were also performed.The symptoms that lasted for a longer time were nausea and vomiting,until 25 mo after the treatment.CONCLUSION:All patients were free from severe symptoms at the end of follow-up.The routine use of SPECT has decreased the incidence of gastrointestinal lesions due to unintended deployment of 90 Y particles. | Iago Rodríguez-Lago Cristina Carretero Maite Herráiz José C Subtil Maite Betés Macarena Rodríguez-Fraile Jesús J Sola José I Bilbao Miguel Muoz-Navas Bruno Sangro | 2013 | World Journal of Gastroenterology2013，19，19： | 2 |
| 7 | Capsule endoscopy capture rate: Has 4 frames-per-second any impact over 2frames-per-second?显示文摘AIM: To compare the current capsule and a new prototype at 2 and 4 frames-per-second, respectively, in terms of clinical and therapeutic impact. METHODS: One hundred patients with an indication for capsule endoscopy were included in the study. All procedures were performed with the new device(SB24). After an exhaustive evaluation of the SB24 videos, they were then converted to 'SB2-like' videos for their evaluation. Findings, frames per finding, and clinical and therapeutic impact derived from video visualization were analyzed. Kappa index for interobserver agreement and χ2 and Student's t tests for qualitative/quantitative variables, respectively, were used. Values of P under 0.05 were considered statistically significant.RESULTS: Eighty-nine out of 100 cases included in the study were ultimately included in the analysis. The SB24 videos detected the anatomical landmarks(Zline and duodenal papilla) and lesions in more patients than the 'SB2-like' videos. On the other hand, the SB24 videos detected more frames per landmark/lesion than the 'SB2-like' videos. However, these differences were not statistically significant(P > 0.05). Both clinical and therapeutic impacts were similar between SB24 and 'SB2-like' videos(K = 0.954). The time spent by readers was significantly higher for SB24 videos visualization(P < 0.05) than for 'SB2-like' videos when all images captured by the capsule were considered. However, these differences become non-significant if we only take into account small bowel images(P > 0.05).CONCLUSION: More frames-per-second detect more landmarks, lesions, and frames per landmark/lesion, but is time consuming and has a very low impact on clinical and therapeutic management. | Ignacio Fernandez-Urien Cristina Carretero Erika Borobio Ana Borda Emilio Estevez Sara Galter Begoa Gonzalez-Suarez Benito Gonzalez Marisol Lujan Jose Luis Martinez Vanessa Martínez Pedro Menchén Javier Navajas Vicente Pons Cesar Prieto Julio Valle | 2014 | World Journal of Gastroenterology2014，20，39： | 2 |
| 8 | Role of Inflammation in the Development of Renal Damage and Dysfunction in Angiotensin II–Induced Hypertension显示文摘 | Tang-Dong Liao Xiao-Ping Yang Yun-He Liu Edward G. Shesely Maria A. Cavasin William A. Kuziel Patrick J. Pagano Oscar A. Carretero | 2008 | Hypertension2008，，2： | 2 |
| 9 | A novel methodology for the monitoring of the agricultural production process based on wireless sensor networks显示文摘 | Soledad Escolar Díaz Jesús Carretero Pérez Alejandro Calderón Mateos Maria-Cristina Marinescu Borja Bergua Guerra | 2011 | Computers and Electronics in Agriculture2011，，2： | 2 |
| 10 | Use of calixarene compounds as selectivity modifiers in capillary electrophoresis separations显示文摘 | Arce L A Carretero S Cruces R C | 1998 | Journal of Chromatography A1998，816，2： | 1 |
| 11 | Determination of the antibacterial drug sulfamethoxazole in pharmaceutical preparations containing trimethoprim by spectrofluorimetry after derivatization with fluorescamine显示文摘 | Blanco CC Carretero SA Peinado FS | 1999 | Fresenius J Anal Chem1999，365，5： | 1 |
| 12 | Antifibrotic effect of Ac-SDKP and angiotensin-converting enzyme inhibition in hypertension 显示文摘 | Rasoul S Carretero OA Peng H | 2004 | J Hypertens2004，22，3： | 1 |
| 13 | Allometric models for nondestructive leaf area estimation in coffee (Coffea Arabica and Coffea canephora)显示文摘 | Antunes W C PompeUi M F Carretero D M | 2008 | Ann Appl Biol2008，153，1： | 1 |
| 14 | Role of AT2 receptors in the cardio- protective effect of AT1 antagonists in mice显示文摘 | Xu J Carretero OA Liu YH | 2002 | Hypm''tension2002，20，3： | 1 |
| 15 | Near-field electromagnetic analysis of perfect black Fresnel zone plates using radial polarization显示文摘 | CARRETERO L PEREZ-MOLINA M BLAYA S | 2011 | Lightwave Technol2011，29，17： | 1 |
| 16 | Antifibrotie effects of N-acetyl-seryl-aspartyl-lysyl-proline on the heart and kidney in aldosterone-salt hypertensive rats 显示文摘 | Peng H M Carretero O A Raij L | 2001 | Hypertertension2001，37，2： | 1 |
| 17 | Deletion of inducible nitric oxide synthase provides cardioprotection in mice with 2-kidney, 1 -clip hypertension 显示文摘 | Sun Y Carretero OA Xu J | 2009 | Hypertension2009，53，1： | 1 |
| 18 | Local angiotensin II aggra- vates cardiac remodeling in hypertension 显示文摘 | Xu J Carretero O A Liao T D | 2010 | Am J Physiol Heart Circ Physio12010，299，5： | 1 |
| 19 | Perivascular superoxide anion contributes to impairment of endothelium-dependent relaxation of gp91phox显示文摘 | Federico E Xiao-Chun Li Oscar A Carretero | 2002 | Circulation2002，106，： | 1 |
| 20 | Occupational exposure to nitrous oxide and sevoflurane during pediatric anesthesia: evaluation of an anesthetic gas extractor显示文摘 | Sanabria Carretero P Rodriguez Prez E Jimnez Mateos E | 2006 | Rev Esp Anestesiol Reanim2006，53，10： | 1 |
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