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| 1 | Transit time ultrasound perivascular flow probe technology is superior to MR imaging on hepatic blood flow measurement in a porcine model显示文摘Background: The hepatic hemodynamics is an essential parameter in surgical planning as well as in various disease processes. The transit time ultrasound(TTUS) perivascular flow probe technology is widely used in clinical practice to evaluate the hepatic inflow, yet invasive. The phase-contrast-MRI(PC-MRI) is not invasive and potentially applicable in assessing the hepatic blood flow. In the present study, we compared the hepatic inflow rates using the PC-MRI and the TTUS probe, and evaluated their predictive value of post-hepatectomy adverse events. Methods: Eighteen large white pigs were anaesthetized for PC-MRI and approximately 75% hepatic resection was performed under a unified protocol. The blood flow was measured in the hepatic artery(Qha), the portal vein(Qpv), and the aorta above the celiac trunk(Qca) using PC-MRI, and was compared to the TTUS probe. The Bland-Altman method was conducted and a partial least squares regression(PLS) model was implemented. Results: The mean Qpv measured in PC-MRI was 0.55 ± 0.12 L/min, and in the TTUS probe was 0.74 ± 0.17 L/min. Qca was 1.40 ± 0.47 L/min in the PC-MRI and 2.00 ± 0.60 L/min in the TTUS probe. Qha was 0.17 ± 0.10 L/min in the PC-MRI, and 0.13 ± 0.06 L/min in the TTUS probe. The Bland-Altman method revealed that the estimated bias of Qca in the PC-MRI was 32%(95% CI:-49% to 15%); Qha 17%(95% CI:-15% to 51%); and Qpv 40%(95% CI:-62% to 18%). The TTUS probe had a higher weight in predicting adverse outcomes after 75% resection compared to the PC-MRI( β= 0.35 and 0.43 vs β = 0.22 and 0.07, for tissue changes and premature death, respectively). Conclusions: There is a tendency of the PC-MRI to underestimate the flow measured by the TTUS probes. The TTUS probe measures are more predictive of relevant post-hepatectomy outcomes. | Mohamed Bekheit Chloe Audebert Petru Bucur Hans Adriaensen Emilie Bled Mylène Wartenberg Irene Vignon-Clementel Eric Vibert | 2018 | Hepatobiliary & Pancreatic Diseases International2018，17，6： | 3 |
| 2 | Determination of 3H and 14C in Organic Sample after Separation through Combustion Method显示文摘 | Simona Popoaca Cristina Bucur Vasile Simionov | 2014 | Journal of Energy and Power Engineering2014，8，10： | 2 |
| 3 | Heparanase: a new metastasis-associated antigen recognized in breast cancer patients by spontaneously induced memory T lymphocytes显示文摘 | Sommerfeldt N Beckhove P Ge Y Sehutz F Choi C Bucur M Domsehke C Sohn C Sehneeweis A Rom J Poll- mann D Leneht D Vlodavsky I Sehirrmaeher V | 2006 | Cancer Res2006，66，15： | 1 |
| 4 | Protein phosphatase 2Areactivates Fox03a through a dynamic interplay with 14-3-3and AKT显示文摘 | Singh A Ye M Bucur O | 2010 | Mol Biol Cell2010，21，6： | 1 |
| 5 | Substituttion of an ala- nine residue for glycine 146 in TMP kinase from Escherichia coli re- sponsible for bacterial hypersensitivity to bromodeoxyuridine 显示文摘 | Tourneux L Bucurenci N Lascu I | 1998 | Journal of Bacteriology1998，180，16： | 1 |
| 6 | Apoptotic pathways in tumor progression and therapy显示文摘 | Melet A Song K Bucur O | 2008 | Adv Exp Med Biol2008，615，： | 1 |
| 7 | Apoptotic pathways in tumor progression and therapy显示文摘 | Melet A Soag K Bucur O | 2008 | Advances in Experimental Medicine and Biology2008，615，： | 1 |
| 8 | Role of aerobic fitness and aging on cerebral white matter integrity 显示文摘 | MARKS B L MADDEN D J BUCUR B | 2007 | Ann NY Acad Sci2007，1097，： | 1 |
| 9 | Apoptotic pathways in tumor progression and therapy显示文摘 | Melet A Song K Bucur O | 2008 | Advances in Experimental Medicine and Biology2008，615，： | 1 |
| 10 | APO2 ligand/tum or necrosis factor-related apoptosis-inducing ligand in prostate cancer therapy显示文摘 | Bucur O Ray S Bucur M C | 2006 | Front Biosci2006，11，： | 1 |
| 11 | Inhibition of neutrophil superoxide production by human plasma alpha 1-antitrypsin显示文摘 | Bucurenci N Blake D R Chidwick K | | 0，，01： | 1 |
| 12 | Breaking tolerance to a tumor-associated viral superantigen as a basis for graft-versus-leukemia reactivity 显示文摘 | Schirrmacher V Muerkoster B Bucur M | 2000 | Int J Cancer2000，87，： | 1 |
| 13 | Partial labyinthectomy petrous apicetomy approach to neoplastic and vascular lesions of the petroclival area显示文摘 | Sekhar LN Schessel DA Bucur SD | 1999 | Neurosurgery1999，44，3： | 1 |
| 14 | Influence of soil erosion on water, soil, humus and nutrient losses in different crop systems in the Moldavian Plateau, Romania显示文摘 | Bucur D Jitareanu G Ailineai C | 2007 | Journal of Food Agriculture & Environment2007，5，2： | 1 |
| 15 | Inhibition of neutrophil superoxide production by human plasma alpha 1-antitrypsin显示文摘 | Bucurenci N Blake DR Chidwick K | 1992 | FEBS Lett1992，300，1： | 1 |
| 16 | Long-term effects of cropping system and mineral fertilization on production and soil fertility in the Moldavian Plain显示文摘 | Ailincai C Jitareanu G Bucur D | 2011 | Cercetari Agronomice in Moldova2011，44，1： | 1 |
| 17 | Cloud9: a software testing service 显示文摘 | Ciortea L Zamfir C Bucur S | 2009 | IEEE Transactions on Operating Systems Review2009，43，4： | 1 |
| 18 | A soft,multilayered lithium-electrolyte interface显示文摘 | BUCUR C B LITA A OSADA N | 2016 | Energy&Environmental Science2016，9，1： | 1 |
| 19 | Evaluation of the impact of three-dimensional vision on laparoscopic performance显示文摘 | Lusch A Bucur PL Menhadji AD | 2014 | J Endourol2014，28，2： | 1 |
| 20 | Effect of propionylcarnitine on changes in endothelial function and plasma levels of adhesion molecules induced by acute exercise in patients with intermittent claudication显示文摘 | Silvestro A Schiano V Bucur R | 2006 | Angiology2006，57，2： | 1 |
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