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| 1 | Vascular invasion in pancreatic cancer:Imaging modalities,preoperative diagnosis and surgical management显示文摘Pancreatic cancer is associated with a poor prognosis,and surgical resection remains the only chance for curative therapy.In the absence of metastatic disease,which would preclude resection,assessment of vascular invasion is an important parameter for determining resectability of pancreatic cancer.A frequent error is to misdiagnose an involved major vessel.Obviously,surgical exploration with pathological examination remains the'gold standard'in terms of evaluation of resectability,especially from the point of view of vascular involvement.However,current imaging modalities have improved and allow detection of vascular invasion with more accuracy.A venous resection in pancreatic cancer is a feasible technique and relatively reliable.Nevertheless,a survival benefit is not achieved by curative resection in patients with pancreatic cancer and vascular invasion.Although the discovery of an arterial invasion during the operation might require an aggressive management,discovery before the operation should be considered as a contraindication.Detection of vascular invasion remains one of the most important challenges in pancreatic surgery.The aim of this article is to provide a complete review of the different imaging modalities in the detection of vascular invasion in pancreatic cancer. | Nicolas C Buchs Michael Chilcott Pierre-Alexandre Poletti Leo H Buhler Philippe Morel | 2010 | World Journal of Gastroenterology2010，16，7： | 29 |
| 2 | Transanal total mesorectal excision: Myths and reality显示文摘Transanal total mesorectal excision(TaTME) is a new and promising approach for the treatment of rectal cancer. Whilst the experience is still limited, there are growing evidences that this approach might overcome the limits of standard low anterior resection. TaTME might help to decrease the conversion rate especially in difficult patients, and to improve the pathological results, while preserving the urogenital function. Evaluation of data from large registries and randomized studies should help to draw firmer conclusions. Beyond these technical considerations, the next challenge seems to be clearly the safe introduction of this approach, motivating the development of dedicated courses. | Nicolas C Buchs Marta Penna Alexander L Bloemendaal Roel Hompes | 2016 | World Journal of Clinical Oncology2016，7，5： | 5 |
| 3 | Transanal total mesorectal excision:a valid option for rectal cancer?显示文摘Low anterior resection can be a challenging operation, especially in obese male patients and in particular after radiotherapy. Transanal total mesorectal excision(Ta TME) might offer technical advantages over laparoscopic or open approaches particularly for tumors in the distal third of the rectum. The aim of this article is to review the current experience with Ta TME. The limits and future developments are also explored. Although the experience with Ta TME is still limited, it might be a promising alternative to laparoscopic TME, especially for difficult cases where laparoscopy is too demanding. The preliminary data on complications and short-term oncological outcomes are good, but also emphasize the importance of careful patient selection. Finally, there is a need for large-scale trials focusing on long-term outcomes and oncological safety before widespread adoption can be recommended. | Nicolas C Buchs Gary A Nicholson Frederic Ris Neil J Mortensen Roel Hompes | 2015 | World Journal of Gastroenterology2015，21，41： | 3 |
| 4 | Cocaine exposure results in forma- tion of dendritic varicosity in rat primary hippocampal neurons显示文摘 | Yao H Bethel-Brown C Buch S | 2009 | Am J Infect Dis2009，5，1： | 1 |
| 5 | Exchange Rates and FDI: Goods versus Capital Market Frictions 显示文摘 | Buch C M Kleinert J | 2008 | World Economy2008，31，9： | 1 |
| 6 | Robotic technology: Optimizing the outcomes in rectal cancer?显示文摘Minimally invasive rectal resection remains a challenging procedure, even in experienced hands. Technical limitations explain at least in part the reasons of a relatively poor adoption of laparoscopy for rectal resection, in particular for low tumors in a deep and narrow pelvis.Robotics is intended to overcome these limitations.Potentially better short-term outcomes have beenpublished: reduced conversion rates, better functional outcomes, shorter learning curve, reduction of positive margins, better specimen… However, robotic surgery has not yet taken over as the gold standard approach for low anterior resection. Several drawbacks might indeed discourage the most fervent surgeon: the size of the robot, the lack of tactile feedback, the risk and difficulties during multiquadrant surgery, and, of course, costs. Whilst new systems might overcome most of these drawbacks, it seems obvious that the development of robotic surgery is underway. Robotics is not just another interesting technical tool, but more a new concept, which should play a role in the future. | Nicolas C Buchs | 2015 | World Journal of Clinical Oncology2015，6，3： | 1 |
| 7 | A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gall- stone disease显示文摘 | Buch S Schafinayer C Volzke H | 2007 | Nat Genet2007，39，： | 1 |
| 8 | Long-term safety of repeated blood-brain barrier opening via focused ultrasound with microbubbles in non-human primates performing a cognitive task显示文摘 | Downs ME Buch A Sierra C | 2015 | PLoS One2015，10，12： | 1 |
| 9 | Dynamic properties of endogenous phytochrome A in Arabidopsis seedlings显示文摘 | Hennig L Buche C Eichenberg K | | 0，，2： | 1 |
| 10 | Genotyping technologies:application to biotransformation enzyme genetic polymorphism screening显示文摘 | ROMKES M BUCH S C | 2005 | Methods Mol Biol2005，291，： | 1 |
| 11 | Genetic investigation of DNA-repair pathway genes PMS2 , ML H1, MSH2, MSH6 , MU TYH , OGG1 and MTH1 in sporadic colon cancer 显示文摘 | Schafmayer C Buch S Egberts JH | 2007 | Int J Cancer2007，121，3： | 1 |
| 12 | The effect of microstructure on abrasive wear of hardfacing alloys显示文摘 | Buchely M F Gutierrez J C Leon L M | 2005 | Wear2005，259，1： | 1 |
| 13 | Citrus flavonoids in fruit and traditional Chinese medicinal food ingredients in China显示文摘 | Lu Y H Zhang C W Bucheli P | 2006 | Plant Foods for Human Nutrition2006，61，2： | 1 |
| 14 | Bioequivalenee revisited:influence of age and sex on CYP enzymes显示文摘 | BEBIA Z BUCH S C WILSON J W | 2004 | Clinical Pharmacology&Therapeutics2004，76，6： | 1 |
| 15 | The effect of microstructure on abrasive wear of hardfacing alloy 显示文摘 | Buchely M F Gutierrez J C Leon L M | 2005 | Wear2005，259，5： | 1 |
| 16 | The effect of microstructure on abrasive wear of hardfacing alloys显示文摘 | Buchely M F Gutierrez J C Le' on L M | | 0，，259： | 1 |
| 17 | Contribution of Enzymic Browning to Color in Sugarcane Juice显示文摘 | BUCHELI C S ROBINSON S P | 1994 | Journal of Agricultural and Food Chemistry1994，42，2： | 1 |
| 18 | Evaluation of an existing screening tool for psoriatic arthritis in people with psoriasis and the development of a new instrument: the Psoriasis Epidemiology Screening Tool (PEST) questionnaire 显示文摘 | Ibrahim GH Buch MH Lawson C | 2009 | Clin Exp Rheumatol2009，27，3： | 1 |
| 19 | Polyphenol oxidase is induced bychilling and wounding in pineapple 显示文摘 | Steffens J R Sawyer B J B Bucheli C S | 2001 | Australian: Journal of plant physiology2001，28，3： | 1 |
| 20 | Distance and international banking 显示文摘 | Buch C M | 2005 | Review of International Economics2005，13，4： | 1 |
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