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| 1 | 水解蛋白质化学改性(英文)显示文摘从含铬废弃物提取的水解蛋白质与不同量的戊二醛 ,在不同的温度下反应。用聚酰胺凝胶电泳法 (SDS -PAGE)分析了改性蛋白质的分子量及分子量分布。用CanonManning粘度法测定了改性产物的粘度。实验表明改性产物的分子量随戊二醛的用量增加而增加。最佳的戊二醛用量约为水解胶原质量的 12 % ,反应温度大于 6 0℃。同时 ,用改性产物做了皮革的填充实验 ,用萤光标记改性胶原 ,通过扫描电镜研究了填充皮革的纤维结构。研究结果表明 ,改性产物具有较好的填充性能 ,采用适当的应用工艺 ,改性产物可能用作皮革填充剂。 | 陈武勇 Brown E M Taylor M M Cooke P H Marmer W N | 2002 | 四川大学学报(工程科学版)2002，34，6： | 9 |
| 2 | Acute effects of physical exercise in type 2 diabetes: A review显示文摘The literature has shown the efficiency of exercise in the control of type 2 diabetes(T2D), being suggested as one of the best kinds of non-pharmacological treatments for its population. Thus, the scientific production related to this phenomenon has growing exponentially. However, despite its advances, still there is a lack of studies that have carried out a review on the acute effects of physical exercise on metabolic and hemodynamic markers and possible control mechanisms of these indicators in individuals with T2 D, not to mention that in a related way, these themes have been very little studied today. Therefore, the aim of this study was to organize and analyze the current scientific production about the acute effects of physical exercise on metabolic and hemodynamic markers and possible control mechanisms of these indicators in T2 D individuals. For such, a research with the following keywords was performed:-exercise; diabetes and post-exercise hypotension; diabetes and excess post-exercise oxygen consumption; diabetes and acute effects in PUBMED, SCIELO and HIGHWIRE databases. From the analyzed studies, it is possible to conclude that, a single exercise session can promote an increase in the bioavailability of nitric oxide and elicit decreases in postexercise blood pressure. Furthermore, the metabolic stress from physical exercise can increase the oxidation of carbohydrate during the exercise and keep it, in high levels, the post exercise consumption of O2, this phenomenon increases the rate of fat oxidation during recovery periods after exercise, improves glucose tolerance and insulin sensitivity and reduces glycemia between 2-72 h, which seems to be dependent on the exercise intensity and duration of the effort. | Ricardo Yukio Asano Marcelo Magalhes Sales Rodrigo Alberto Vieira Browne José Fernando Vila Nova Moraes Hélio José Coelho Júnior Milton Rocha Moraes Hebert Gustavo Simoes | 2014 | World Journal of Diabetes2014，5，5： | 8 |
| 3 | Acute pancreatitis in aging animals:Loss of pancreatitis-associated protein protection?显示文摘AIM:To investigate the effect of age on severity of acute pancreatitis(AP) using biochemical markers,histology and expression of the protective pancreatitisassociated proteins(PAPs).METHODS:AP was induced via intraductal injection of 4% sodium taurocholate in young and old rats.Sera and pancreata were assayed at 24 h for the parameters listed above;we also employed a novel molecular technique to assess bacterial infiltration using polymerase chain reaction to measure bacterial genomic ribosomal RNA.RESULTS:At 24 h after induction of AP,the pancreata of older animals had less edema(mean ± SE histologic score of young vs old:3.11 ± 0.16 vs 2.50 ±-0.11,P < 0.05),decreased local inflammatory response(histologic score of stromal infiltrate:3.11 ± 0.27 vs 2.00 ± 0.17,P < 0.05) and increased bacterial infiltration(174% ± 52% increase from sham vs 377% ± 4%,P < 0.05).A decreased expression of PAP1 and PAP2 was demonstrated by Western blotting analysis and immunohistochemical staining.There were no differences in serum amylase and lipase activity,or tissue myeloperoxidase or monocyte chemotactic protein-1 levels.However,in the most-aged group,serum C-reactive protein levels were higher(young vs old:0.249 ± 0.04 mg/dL vs 2.45 ± 0.68 mg/dL,P < 0.05).CONCLUSION:In older animals,there is depressed PAP expression related to a blunted inflammatory response in AP which is associated with worsened bacterial infiltration and higher C-reactive protein level;this may explain the more aggressive clinical course. | Sophia Fu Albert Stanek Cathy M Mueller Nefertti A Brown Chongmin Huan Martin H Bluth Michael E Zenilman | 2012 | World Journal of Gastroenterology2012，18，26： | 5 |
| 4 | Chronic overexpression of PNPLA3^sup I148M^ in mouse liver causes hepatic steatosis显示文摘 | Li John Zhong Huang Yongcheng Karaman Ruchan Ivanova Pavlina T Brown H Alex Roddy Thomas Castro-Perez Jose Cohen Jonathan C Hobbs Helen H | 2012 | EN2012，，11： | 3 |
| 5 | Patterns of genomic and phenomic diversity in wine and table grapes显示文摘Grapes are one of the most economically and culturally important crops worldwide,and they have been bred for both winemaking and fresh consumption.Here we evaluate patterns of diversity across 33 phenotypes collected over a 17-year period from 580 table and wine grape accessions that belong to one of the world’s largest grape gene banks,the grape germplasm collection of the United States Department of Agriculture.We find that phenological events throughout the growing season are correlated,and quantify the marked difference in size between table and wine grapes.By pairing publicly available historical phenotype data with genome-wide polymorphism data,we identify large effect loci controlling traits that have been targeted during domestication and breeding,including hermaphroditism,lighter skin pigmentation and muscat aroma.Breeding for larger berries in table grapes was traditionally concentrated in geographic regions where Islam predominates and alcohol was prohibited,whereas wine grapes retained the ancestral smaller size that is more desirable for winemaking in predominantly Christian regions.We uncover a novel locus with a suggestive association with berry size that harbors a signature of positive selection for larger berries.Our results suggest that religious rules concerning alcohol consumption have had a marked impact on patterns of phenomic and genomic diversity in grapes. | ZoëMigicovsky Jason Sawler Kyle M Gardner Mallikarjuna K Aradhya Bernard H Prins Heidi R Schwaninger Carlos D Bustamante Edward S Buckler Gan-Yuan Zhong Patrick J Brown Sean Myles | 2017 | Horticulture Research2017，4，1： | 3 |
| 6 | The NLANR network analysis infrastructure 显示文摘 | McGregor T Braun H W Brown J | 2000 | IEEE Communications Magazine2000，38，5： | 2 |
| 7 | Association between raw wool characteristics and processing to top 显示文摘 | Rottenbury R A Andrews MW Brown G H | 1983 | Textile Res J1983，，53： | 2 |
| 8 | B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy显示文摘 | Vijay K Kuchroo Mercy Prabhu Das Julia A Brown Ann M Ranger Scott S Zamvil Raymond A Sobel Howard L Weiner Nasrin Nabavi Laurie H Glimcher | 1995 | Cell1995，，5： | 2 |
| 9 | The influence of C:P ratio on the biological degradation of municipal solid waste显示文摘 | Brown K H Bouwkamp J C Couin F R | 1998 | Compost Science & Utilization1998，6，1： | 2 |
| 10 | Texturing of textile filament yarns based on poly(trimthylene terephthalate)显示文摘 | Brown H S Chuah H H | 1997 | Chem Fibers Int1997，47，1： | 2 |
| 11 | 气缸孔粗糙度对机油耗影响的试验研究显示文摘侧重于内燃机机油耗控制中的一个重要因素。以前的研究工作已经通过理论或试验方法建立了气缸孔粗糙度与机油耗之间的关系。在本研究中,利用回归分析和新的瞬态放射性示踪剂机油耗测量法所得到的试验数据用统计学方法推导出了一个数学模型。该模型可预测机油耗随气缸孔粗糙度变化的期望值,并能提出确定和控制最低机油耗的重要气缸孔表面粗糙度参数。 | Hill S H Kantola T C Brown J R 孙书麒 | 1998 | 国外内燃机1998，30，3： | 2 |
| 12 | 从精准农业至自动农业:高科技产品推动农业革命显示文摘本文以Kinze公司的自动化农机设备为案例,对以全球定位系统(GPS)定位为基础条件的智能化农业机械定位与控制系统进行了系统阐述,对智能农机在导航、障碍探测和作业执行等方面协同工作原理进行了详细说明,并由此提出自动化农业机械应用和发展趋势,以及工业信息化技术在传统农机实现智能化过程中的支撑作用。 | Jeremy H Brown 李玉荣 刘珊 | 2016 | 世界农业2016，，4： | 2 |
| 13 | Steady State plasma- noradrenaline kinetics in quadriplegic chronic spinal cordinjury patients 显示文摘 | Krum H Brown D J Rowe P R | 1990 | J Auton Pharmacol1990，10，4： | 1 |
| 14 | Ear photosynthesis, carbonisotope discrimination and the contribution of respiratory CO2 to differences in grain mass in durum wheat显示文摘 | A raus J L Brown R H Febrero A | 1993 | Plant Cell and Enviroment1993，16，： | 1 |
| 15 | Analysis of translation elongation factors from wheat during development and following heat shock显示文摘 | Gallic D R Le H Caldwell C Browning K S | 1998 | Biochemical and Biophysical Research Communications1998，245，： | 1 |
| 16 | Invasive fungal infections:a review of epidemiology and management options 显示文摘 | ENOCH V A LUDLAM H A BROWN N M | 2006 | J Med Microbiol2006，55，7： | 1 |
| 17 | Structure and polymorphic map of human lipoprotein lipase gene显示文摘 | Oka K Tkalcevic GT Nakano T Tucker H Ishimura-Oka K Brown WV | 1990 | Biochim Biophys Acta1990，1049，1： | 1 |
| 18 | Computationally efficient algorithms for cyclic spectral analysis显示文摘 | ROBERTS R S BROWN W A LOOMI H H | 1991 | IEEE Signal Processing Magazine1991，8，2： | 1 |
| 19 | Interaction between the APOC3 gene promoter polymorphisms,saturated fat intake and plasma lipoproteins显示文摘 | Ordovas JM Campos H | 2003 | A therosclerosis2003，170，2： | 1 |
| 20 | Molecular similarity based on novel atom-type electrotopological state indices显示文摘 | Kier L B Brown B B | 1995 | J Chem Inf Comput Sci1995，35，6： | 1 |
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