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| 1 | Consensus statement AIGO/SICCR diagnosis and treatment of chronic constipation and obstructed defecation(Part Ⅱ:Treatment)显示文摘The second part of the Consensus Statement of the Italian Association of Hospital Gastroenterologists and Italian Society of Colo-Rectal Surgery reports on the treatment of chronic constipation and obstructed defecation.There is no evidence that increasing fluid intake and physical activity can relieve the symptoms of chronic constipation.Patients with normal-transit constipation should increase their fibre intake through their diet or with commercial fibre.Osmotic laxatives may be effective in patients who do not respond to fibre supplements.Stimulant laxatives should be reserved for patients who do not respond to osmotic laxatives.Controlled trials have shown that serotoninergic enterokinetic agents,such as prucalopride,and prosecretory agents,such as lubiprostone,are effective in the treatment of patients with chronic constipation.Surgery is sometimes necessary.Total colectomy with ileorectostomy may be considered in patients with slow-transit constipation and inertia coli who are resistant to medical therapy and who do not have defecatory disorders,generalised motility disorders or psychological disorders.Randomised controlled trials have established the efficacy of rehabilitative treatment in dys-synergic defecation.Many surgical procedures may be used to treat obstructed defecation in patients with acquired anatomical defects,but none is considered to be the gold standard.Surgery should be reserved for selected patients with an impaired quality of life.Obstructed defecation is often associated with pelvic organ prolapse.Surgery with the placement of prostheses is replacing fascial surgery in the treatment of pelvic organ prolapse,but the efficacy and safety of such procedures have not yet been established. | Antonio Bove Massimo Bellini Edda Battaglia Renato Bocchini Dario Gambaccini Vincenzo Bove Filippo Pucciani Donato Francesco Altomare Giuseppe Dodi Guido Sciaudone Ezio Falletto Vittorio Piloni | 2012 | World Journal of Gastroenterology2012，18，36： | 33 |
| 2 | Consensus statement AIGO/SICCR:Diagnosis and treatment of chronic constipation and obstructed defecation(partⅠ:Diagnosis)显示文摘Chronic constipation is a common and extremely troublesome disorder that significantly reduces the quality of life,and this fact is consistent with the high rate at which health care is sought for this condition.The aim of this project was to develop a consensus for the diagnosis and treatment of chronic constipation and obstructed defecation.The commission presents its results in a 'Question-Answer' format,including a set of graded recommendations based on a systematic review of the literature and evidence-based medicine.This section represents the consensus for the diagnosis.The history includes information relating to the onset and duration of symptoms and may reveal secondary causes of constipation.The presence of alarm symptoms and risk factors requires investigation.The physical examination should assess the presence of lesions in the anal and perianal region.The evidence does not support the routine use of blood testing and colonoscopy or barium enema for constipation.Various scoring systems are available to quantify the severity of constipation;the Constipation Severity Instrument for constipation and the obstructed defecation syndrome score for obstructed defecation are the most reliable.The Constipation-Related Quality of Life is an excellent tool for evaluating the patient's quality of life.No single test provides a pathophysiological basis for constipation.Colonic transit and anorectal manometry define the pathophysiologic subtypes.Balloon expulsion is a simple screening test for defecatory disorders,but it does not define the mechanisms.Defecography detects structural abnormalities and assesses functional parameters.Magnetic resonance imaging and/or pelvic floor sonography can further complement defecography by providing information on the movement of the pelvic floor and the organs that it supports.All these investigations are indicated to differentiate between slow transit constipation and obstructed defecation because the treatments differ between these conditions. | Antonio Bove Filippo Pucciani Massimo Bellini Edda Battaglia Renato Bocchini Donato Francesco Altomare Giuseppe Dodi Guido Sciaudone Ezio Falletto Vittorio Piloni Dario Gambaccini Vincenzo Bove | 2012 | World Journal of Gastroenterology2012，18，14： | 20 |
| 3 | 有百年历史的日益严重的毁灭性柑桔病害——黄龙病显示文摘黄龙病是柑桔的一种毁灭性病害,已对世界柑桔产业的发展构成严重的威胁,并在慢慢的向新的柑桔种植区蔓延。本文对黄龙病的历史、病原、生物学特性、流行、检测、地理分布和防控措施等做了详细的论述。黄龙病于1919年在中国南方首次报道,现在亚洲、非洲、大洋洲、南北美洲的40多个国家都有黄龙病发生。黄龙病病原是韧皮部杆菌属革兰氏阴性菌,属于难培养细菌,南非的"青果病"(greening)、菲律宾的"斑叶病"(mottleleaf)、印度的"梢枯病"(dieback)、印度尼西亚的"叶脉韧皮部退化病"(vein phloem degeneration)都是由该病原菌引起的。黄龙病病原菌属于韧皮部杆菌属(Candidatus liberibacter),迄今,已知该病原菌有三个种:亚洲种黄龙病菌主要存在于亚洲地区,巴西和美国(佛罗里达)也有分布,非洲种黄龙病菌及其亚种"capensis"存在于非洲国家,美洲种黄龙病菌存在于巴西。世界各地的黄龙病症状实质上是相同的。病株叶片斑驳,引起黄梢,是该病早期典型的症状,病树植株矮化,树势衰弱,结果少,果实变小畸形,着色差(青果),并从果蒂处开始着色(与正常果着色顺序相反)。黄龙病可通过嫁接从柑桔传到柑桔,也可通过菟丝子从柑桔传到长春花。非洲柑桔木虱和亚洲柑桔木虱是天然的传播媒介。黄龙病有两种类型:一种为非洲的热敏感型,由非洲柑桔木虱传播,发病适温为22~25℃;另一种为亚洲的耐热型,由亚洲柑桔木虱传播,可忍受30℃以上的高温。黄龙病病原菌虽可由电镜检出,但是一般用其它的实验方法来进行常规的检测。不宜采用单克隆抗体的酶联免疫吸附检测。比较好的方法是采用DNA探针的斑点杂交试验和利用基于16SrRNA或rplKAJL-rpoBC操纵子序列的特异性引物的各种PCR(常规PCR,巢式PCR,多重PCR)。由于至今黄龙病还无法治疗,现在普遍采用挖除病株结合化学防治传病媒介,以清除感染源进行预防。为了防止黄龙病和柑桔木虱的进一步国际传播,必须制定严格的检疫措施。 | J·seph Marie Bove 付惠敏(编译) 陈传武(编译) 白先进(编译) 赵学源(译校) | 2011 | 广西农学报2011，26，4： | 12 |
| 4 | Comparison of PM_(10) concentrations and metal content in three different sites of the Venice Lagoon: An analysis of possible aerosol sources显示文摘The Venice Lagoon is exposed to atmospheric pollutants from industrial activities, thermoelectric power plants, petrochemical plants, incinerator, domestic heating, ship traffic, glass factories and vehicular emissions on the mainland. In 2005, construction began on the mobile dams (MOSE), one dam for each channel connecting the lagoon to the Adriatic Sea as a barrier against high tide. These construction works could represent an additional source of pollutants. PM 10 samples were taken on random days between 2007 and 2010 at three different sites: Punta Sabbioni, Chioggia and Malamocco, located near the respective dam construction worksites. Chemical analyses of V, Cr, Fe, Co, Ni, Cu, Zn, As, Mo, Cd, Sb, Tl and Pb in PM 10 samples were performed by Inductively coupled plasma-quadrupole mass spectrometry (ICP-QMS) and results were used to identify the main aerosol sources. The correlation of measured data with meteorology, and source apportionment, failed to highlight a contribution specifically associated to the emissions of the MOSE construction works. The comparison of the measurements at the three sites showed a substantial homogeneity of metal concentrations in the area. Source apportionment with principal component analysis (PCA) and positive matrix factorization (PMF) showed that a four principal factors model could describe the sources of metals in PM 10 . Three of them were assigned to specific sources in the area and one was characterised as a source of mixed origin (anthropogenic and crustal). A specific anthropogenic source of PM 10 rich in Ni and Cr, active at the Chioggia site, was also identified. | Daniele Contini Franco Belosi Andrea Gambaro Daniela Cesari Angela Maria Stortini Maria Chiara Bove | 2012 | Journal of Environmental Sciences2012，24，11： | 4 |
| 5 | Service worker role in encouraging customer organizational citizenship behaviors显示文摘 | Liliana L. Bove Simon J. Pervan Sharon E. Beatty Edward Shiu | 2008 | Journal of Business Research2008，，7： | 2 |
| 6 | 有百年历史的日益严重的毁灭性柑桔病害——黄龙病(续)显示文摘黄龙病的防控现在还没有办法治愈黄龙病。当发现黄龙病不是病毒病,而是细菌性病害后,南非、印度尼西亚、台湾等国家和地区都尝试过树干注射四环素等抗生素防治的办法,但很快就由于生态学上的原因而放弃了。其主要是因为四环素是抑菌性的而不是杀菌性的,并且每年都必须重复处理。 | J.seph Marie Bove 付惠敏 陈传武 白先进 赵学源 | 2011 | 广西农学报2011，26，6： | 2 |
| 7 | Treatment of femoral diaphyseal non-unions:our experience显示文摘 | Benazzo F Mosconi M Bove F | 2010 | Injury2010，41，11： | 1 |
| 8 | The incidence and risk of acute renal failure after cardiac surgery显示文摘 | Bove T Calabro MG Landoni G | | 0，，02： | 1 |
| 9 | Characterization of wound-responsive RNA-binding proteins and their splice variants in Arabi- dopsis显示文摘 | BOVE J KIM C Y GIBSON C A | 2008 | Plant Molecular Biology2008，67，12： | 1 |
| 10 | Primary Sjogren syn- drome:an update on current pharmacotherapy options and future di- rections显示文摘 | Brito-Zeron P Siso-Almirall A Bove A | 2013 | Expert Opin Pharmacother2013，14，3： | 1 |
| 11 | Predicting ad- verse outcomes in primary Sjogren's syndrome: identification of prognostic factors显示文摘 | Brito-Zeron P Ramos-Casals M Bove A | 2007 | Rhenmatology2007，46，8： | 1 |
| 12 | Irled-based patient localization for linac radiosurgery-a preliminary report显示文摘 | Meeks SL Bove FJ | 1998 | Int J Radiation Oncology Biol Phys1998，41，2： | 1 |
| 13 | Effectiveness and safety of prehospital urapidl for hypertensive emergencies显示文摘 | Bove FI de Cabo FF | 2001 | Am J Emerg Med2001，19，2： | 1 |
| 14 | Mitochondria and programmed ceil death in Parkinson' s disease: apoptosis and beyond显示文摘 | Perier C Bove J Vila M | 2012 | Antioxid Redox Signal2012，16，9： | 1 |
| 15 | Diagnosis and management of laryngopharyngeal reflux disease 显示文摘 | Bove M J Rosen C | 2006 | Curt Opin Otolaryngol Head Neck Surg2006，14，3： | 1 |
| 16 | Proteasome inhibition and Parkinson' s disease modeling 显示文摘 | Bove J Zhou C Jackson-lewis V Taylor J Chu Y Rideout H J | 2006 | Ann Neurol2006，60，： | 1 |
| 17 | Electric power generation from landfill gas using traditional and innovative technologies显示文摘 | BOVE R LUNGHI P | 2006 | Energy Conversion and Management2006，，47： | 1 |
| 18 | lntranigral infusion of intedeukin-1 beta activates astrocytes and protects from subsequent 6-hydroxydopamine 显示文摘 | Saura J Pares M Bove J | 2003 | Neuro-toxicity J Neurochem2003，85，3： | 1 |
| 19 | Development of d rapid yeast estrogen bioassay, based on the expression of green fluorescent protein显示文摘 | Bovee T F H Helsdingen R J R Koks P D | 2004 | Gene2004，325，： | 1 |
| 20 | Apoptosis-inducing factor deficiency sensitizes dopaminergic neurons to parkinsonian neurotoxins 显示文摘 | PER1ER C BOVE J DEHAY B | 2010 | Ann Neurol2010，68，2： | 1 |
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