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| 1 | Modalities of testing Helicobacter pylori in patients with nonmalignant bile duct diseases显示文摘AIM: This paper describes the procedure of detection ofHelicobacter pylori ( H. pylori) in bile specimens in patientssuffering from benign diseases of biliary ducts (lithiasiswith/without nonspecific cholangitis).METHODS: The group of 72 patients entering the studyconsisted of 32 male and 40 female (45 % and 55 %,respectively). Bile was obtained during ERCP in 68 patients,and during cholecystectomy in 4 patients. A fast urease test(FUT) to determine the existence of H. pylori in gastricmucosa was carried out for all the patients during theendoscopic examination. The existence of genetic materialof H. pylori was determined by detection of ure A gene bythe method of nested PCR. The results of this reaction wereshown by electrophoresis on l0 g@ L-1 agarose gel in a bandof 256 bp.RESULTS: The majority of the patients included in our studyhad biliary lithiasis without signs of cholangitis (48 patients,67 %), whereas other patients were complicated bycholangitis (17 patients, 24 %). Seven patients (9 %) hadnormal ERCP, forming thus the control group. In the groupof patients with lithiasis 26 patients (54.2 %) had positivePCR of H. pylori in bile and among the patients withassociated cholangitis positive PCR was detected in 9patients (52.9 % ). Among the seven patients with nornalERCP only one (14 %) had positive PCR of H. pylori. Ahigh percentage of H. pylori infection of gastric mucosawas observed (57 patients, 79 % ) : It was also observed thatits slightly higher positivity was in the patients with distinctbile pathology: 81% FUT positive patients in the group withcholedocholithiasis alone and 76 % in the group withcholedocholithiasis associated with cholangitis. Seventy-onepercent of the patients with regular findings had positive FUT.CONCLUSION: The prevalence of H. pylori infection both inbile and in gastric mucosa in patients with benign diseasesof biliary ducts does not show a statistically significantdifference in relation to the prevalence of the same with thepatients with normal ERCP. The existence of H. pyloriinfection possibly does not play a role in pathogenesis ofbenign biliary diseases. | Milutin Bulajic Bojan Stimec Miroslav Milicevic Matthias Loehr Petra Mueller Ivan Boricic Nada Kovacevic Mirko Bulajic | 2002 | World Journal of Gastroenterology2002，8，2： | 6 |
| 2 | Hepatitis C virus genotypes in Serbia and Montenegro: The prevalence and clinical signifi cance显示文摘AIM: To investigate the prevalence of hepatitis C virus (HCV) genotypes in Serbia and Montenegro and their in? uence on some clinical characteristics in patients with chronic HCV infection.METHODS: A total of 164 patients was investigated. Complete history, route of infection, assessment of al-cohol consumption, an abdominal ultrasound, standard biochemical tests and liver biopsy were done. Gene se-quencing of 5’ NTR type-specifi c PCR or commercial kits was performed for HCV genotyping and subtyping. The SPSS for Windows (version 10.0) was used for univariate regression analysis with further multivariate analysis. RESULTS: The genotypes 1, 2, 3, 4, 1b3a and 1b4 were present in 57.9%, 3.7%, 23.2%, 6.7%, 6.7% and 1.8% of the patients, respectively. The genotype 1 (mainly the subtype 1b) was found to be independent of age in sub-jects older than 40 years, high viral load, more severe necro-in? ammatory activity, advanced stage of fi brosis, and absence of intravenous drug abuse. The genotype 3a was associated with intravenous drug abuse and the age below 40. Multivariate analysis demonstrated age over 40 and intravenous drug abuse as the positive pre-dictive factors for the genotypes 1b and 3a, respectively. CONCLUSION: In Serbia and Montenegro, the geno-types 1b and 3a predominate in patients with chronic HCV infection. The subtype 1b is characteristic of older patients, while the genotype 3a is common in drug abus-ers. Association of the subtype 1b with advanced liverdisease, higher viral load and histological activity sug-gests earlier infection with this genotype and eventually its increased pathogenicity. | Neda Svirtlih Dragan Delic Jasmina Simonovic Djordje Jevtovic Ljubisa Dokic Eleonora Gvozdenovic Ivan Boricic Dragica Terzic Sladjana Pavic Gorana Neskovic Sonja Zerjav Vladimir Urban | 2007 | World Journal of Gastroenterology2007，13，3： | 5 |
| 3 | One hundred laparoseopie ehole- doehotomies with primary closure of the common bile duet 显示文摘 | Decker G Boric F Miilat B | 2003 | Surg Endosc2003，17，1： | 1 |
| 4 | Cychn A andβ- catenin expression in actinic kemtosis, Bowen' s disease and invasive squamous cell carcinoma of the skin显示文摘 | Brasanac D Boricic I Todorovic V | 2005 | Br J Dermatol2005，153，6： | 1 |
| 5 | Elemental flux between al- gae and duckweeds (Lemna gibba) during competition 显示文摘 | Szado S Braun M Borics G | 1999 | Arch Hydmbiol1999，146，3： | 1 |
| 6 | Clonidine-induced nitric oxide-dependent vasorelaxation mediated by endothelial alpha ( 2 ) -adrenoceptor activation 显示文摘 | FIGUEROA X F POBLETE M I BORIC M P | 2001 | Br J Pharmacol2001，134，5： | 1 |
| 7 | Retroperitoneal kaposiform hemangioendothelioma with tufted angioma-like features in an infant with Kasabach-Merritt syndrome 显示文摘 | Brasanac D Janic D Boricic I | 2003 | Pathol Int2003，53，9： | 1 |
| 8 | Total mandibularreconstruction after resection of rare 'honeycomb -like'ameloblastic carcinoma--a case report 显示文摘 | Jeremic JV Nikolic ZS Boricic IV | 2010 | J CraniomaxillofacSurg2010，38，6： | 1 |
| 9 | Autoantibodies characteristic for autoimmune hepatitis found in chronic hepatitis C 显示文摘 | Pavic S Simonovic J Boricic I | 2003 | Srp Arh Celok Lek2003，131，： | 1 |
| 10 | Use of phytoplankton assemblages for monitoring ecological status of lakes within the water frameword directive:the assemblage index 显示文摘 | PADISAK J BORICS G GRIGORSZKY I | 2006 | Hydrobiologia2006，553，： | 1 |
| 11 | Clinical characteristics and prognostic factors of pulmonary MALT lymphoma显示文摘 | Boric R Wislez M Thabut G | 2009 | Eur Respir J2009，34，6： | 1 |
| 12 | 显示文摘 | Landolt D The influence of boric acid and sulfate ions on the hydrogen formation in Ni-Fe plating electrolytes | 2000 | Electrochim Acta2000，45，： | 1 |
| 13 | One hundred laparo- scopic choledochotomes with primary closure of common duet显示文摘 | Decker G Boric F Millat B | 2003 | Surg Endosc2003，17，1： | 1 |
| 14 | Use of phytoplankton assemblages for monitoring ecological status of lakes within the water framework directive: the assemblage index显示文摘 | Padisák J Borics G Grigorszky I Soróczki-Pintér é | 2006 | Hydrobiologia2006，553，1： | 1 |
| 15 | A new evaluation technique of potamo-plankton for the assessment of the ecological status of rivers 显示文摘 | Borics G Varbiro G Grigorszky I | 2007 | Archiv fuer Hydrobiologie Supplement2007，17，34： | 1 |
| 16 | Simulating the effects of Glen Canyon Dam releases on Grand Canyon Riv- er Trips 显示文摘 | Ronald E Boric Heaton Underhill A | 1989 | Environmental Management1989，13，3： | 1 |
| 17 | Cyclin A and beta-catenin expression in actinic keratosis, Bowen,s disease and in-vasive squamous cell carcinoma of the skin 显示文摘 | Brasanac D Boricic I Todorovic V | 2005 | Br J Dermatol2005，153，6： | 1 |
| 18 | Uhrasonography of major s-alivary glands could be an alternative tool to sialoscintigraphy in the American-European classification criteria for primary Sjogren's syndrome显示文摘 | Milic V Petrovic R Boricic I | 2012 | Rheumatology(Oxford)2012，51，6： | 1 |
| 19 | Immunohistochemical analysis of alpha-SMA and GFAP expression in liver stellate cells显示文摘 | Tomanovic N Boricic I Brasanac D | 2006 | Vojnosanit Pregl2006，63，6： | 1 |
| 20 | Inhibitors of histone demethylation and histone deacetylation cooperate in regulating gene expression and inhibiting growth in human breast cancer cells显示文摘 | Huang Y Vasilatos SN Boric L | | 0，，： | 1 |
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