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| 1 | 亚太若干地区恶性肿瘤流行趋势分析显示文摘目的 研究亚洲太平洋若干地区恶性肿瘤造成的疾病负担及其流行趋势。方法 采用世界标化人口计算恶性肿瘤年发病率和死亡率,提出重点防治的癌症。在估计人口增长和人口老化的基础上,预测今后50年恶性肿瘤流行趋势。结果 亚太若干地区2000年恶性肿瘤新发病例300多万,死亡200多万。现患病例540万。最常发生的是胃癌(占16.4%).肺癌(占15.8%)和肝癌(占13.6%)。预计2050年恶性肿瘤发病和死亡例数将是2000年的2倍以上,新发病例和死亡病例将分别达到780万和570万。结论 随着人口增长和平均期望寿命增加,恶性肿瘤造成的疾病负担将明显加重。 | 蔡琳 Binh Yang Donald M.Parkin 张作风 | 2004 | 肿瘤2004，24，5： | 57 |
| 2 | Estimation of internal nutrient release in large shallow Lake Taihu, China显示文摘Based on field investigation of wave, sediment suspension and the changes in nutrient concentration of the water column in Lake Taihu, China, we proposed two release models to quantify nutrient release under static and dynamic conditions, respectively. Under static conditions, nutrient release from sediments to the overlying water mainly depends on chemical diffusion induced by concentration gradient, in which the nutrient release is controlled by the temperature, dissolved oxygen concentration in the sediment-water interface, oxidation-reduction potential and the concentration difference between porewater and overlying water. Under dynamic condition (or disturbed condition),both dissolved and particulate nutrients in sediments are released into the water column because of wind-induced sediment suspension. The amount of nutrient release under dynamic conditions is larger than that under the static condition. The release of dissolved nutrients, however, does not increase because the wind induced turbulence made oxidation of metallic elements such as Fe (ferric iron), Mn which are capable of precipitating soluble reactive phosphate (SRP). Under dynamic conditions, therefore, the release of total phosphorus (TP) increases dramatically but the release of SRP is close to those under static conditions. In sediments of Lake Taihu, high Fe content leads to a high ratio of Fe to P contents in sediments (Fe:P ratio). Under dynamic conditions, therefore, nutrient release is controlled by the intensity of disturbance, sediment consolidation and nutrient content in sediments.As for dissolved nutrients, especially SRP, the release is also controlled by the intensity of dynamic re-oxidation, Fe content in sediments and nutrient concentration gradient between porewater and overlying water. Based on these two release modes, the release flux in Lake Taihu has been estimated. In the static condition (i.e. laboratory experimental condition), total release of NH4+-N for whole lake is ca. 10,000 ton/a, and PO43--P is ca. 900 ton/a. In the dynamic condition, nutrient release following sediment suspension was estimated according to three different intensities of wind forcing which were defined as 'calm' (wind speed is less than 2 m/s), 'gentle' (wind speed is greater than 2 m/s and less than 6 m/s) and 'gust' (wind speed is greater than 6 m/s). The release rate in the condition of 'calm' was estimated in terms of the nutrient release in the laboratory experimental static condition; whereas the release rate in conditions of 'gentle' and 'gust' was estimated in terms of measurement during sediment resuspension conducted in flume experiments. With the observation of wind velocity and frequency in 2001, each type of wind forcing took the frequency of 12%, 82% and 6% for 'calm', 'gentle' and 'gust', respectively. The yearly release of nitrogen was 81,000 ton and phosphorus was 21,000 ton, which is about 2-6 folds of annual external loading, respectively. | QIN Boqiang, ZHU Guangwei, ZHANG Lu, LUO Liancong, GAO Guang & GU Binhe Nanjing Institute of Geography & Limnology, Chinese Academy of Sciences, Nanjing 210008, China Everglades Department, South Florida Water Management District, 3301 Gun Club Road, West Palm Beach, FL 33406, USA | 2006 | Science China Earth Sciences2006，49，z1： | 37 |
| 3 | 东亚地区癌症负担和预防策略显示文摘目的:探讨东亚地区当前的癌症负担、危险因素、预防和控制策略。方法:应用全球癌症数据库和5大洲癌症发病资料,利用发病率、死亡率和患病率指标估计东亚地区的癌症负担,分析主要癌症的预防策略。结果:东亚地区癌症的年新发病例数为280万,死亡病例200多万,现患病例490万。最常见的5种癌症是胃癌、肺癌、肝癌、食管癌和结直肠癌,占东亚地区癌症年新发病例数的68%(分别占癌症年新发病例数的18.7%、16.9%、14.2%、9.4%和9.1%)。预计2050年的癌症新发病例数将达600万,死亡病例450万。结论:癌症是目前和今后东亚地区面临的严重公共卫生问题,必须贯彻以预防为主的方针。 | 蔡琳 GOLDSTEIN Binh Yang PARKIN Donald Maxwell 张作风 | 2008 | 肿瘤2008，28，5： | 36 |
| 4 | 联合应用MDM2和CDK4免疫组化标记有助于鉴别低级别骨肉瘤与其它骨原发性纤维骨性病变显示文摘低级别骨肉瘤是较为少见的恶性肿瘤,依据肿瘤原发位置与骨皮质的关系可分为两种亚型,即骨旁骨肉瘤和低级别中央型骨肉瘤。两者组织学形态相似,主要由轻到中度异型的梭形细胞和分化良好的网状新生骨小梁结构组成。 | Dujardin F Binh M B Bouvier C 孙琦 樊祥山 | 2011 | 临床与实验病理学杂志2011，27，12： | 19 |
| 5 | A hybrid machine learning ensemble approach based on a Radial Basis Function neural network and Rotation Forest for landslide susceptibility modeling:A case study in the Himalayan area, India显示文摘In this paper, a hybrid machine learning ensemble approach namely the Rotation Forest based Radial Basis Function(RFRBF) neural network is proposed for spatial prediction of landslides in part of the Himalayan area(India). The proposed approach is an integration of the Radial Basis Function(RBF) neural network classifier and Rotation Forest ensemble, which are state-of-the art machine learning algorithms for classification problems. For this purpose, a spatial database of the study area was established that consists of 930 landslide locations and fifteen influencing parameters(slope angle, road density, curvature, land use, distance to road, plan curvature, lineament density, distance to lineaments, rainfall,distance to river, profile curvature, elevation, slope aspect, river density, and soil type). Using the database, training and validation datasets were generated for constructing and validating the model. Performance of the model was assessed using the Receiver Operating Characteristic(ROC) curve, area under the ROC curve(AUC), statistical analysis methods, and the Chi square test. In addition, Logistic Regression(LR), Multi-layer Perceptron Neural Networks(MLP Neural Nets), Na(?)ve Bayes(NB), and the hybrid model of Rotation Forest and Decision Trees(RFDT) were selected for comparison. The results show that the proposed RFRBF model has the highest prediction capability in comparison to the other models(LR, MLP Neural Nets, NB, and RFDT); therefore, the proposed RFRBF model is promising and should be used as an alternative technique for landslide susceptibility modeling. | Binh Thai Pham Ataollah Shirzadi Dieu Tien Bui Indra Prakash M.B.Dholakia | 2018 | International Journal of Sediment Research2018，33，2： | 14 |
| 6 | Saposhnikoviae divaricata:a phytochemical,pharmacological,and pharmacokinetic review显示文摘Saposhnikoviae divaricata(Turcz.) Schischk(SD) is a traditional Chinese herb commonly used to treat clinical conditions such as rheumatism and allergic rhinitis. This review article evaluates a collection of works on in vitro and biochemical studies of SD. The discourse on the diverse class of chromones and coumarins in SD offers an insight to the pharmacological effects of these bioactive constituents as anti-inflammatory, analgesic, immunoregulatory, antioxidative, and anti-proliferative agents. It is highlighted that there is a structural relationship between the constituents and bioactive activities, which in effect provides a valid reasoning and reaffirm the use of SD in the treatment of the pathologies in Chinese medicine. | Jenny Kreiner Edwin Pang George Binh Lenon Angela Wei Hong Yang | 2017 | Chinese Journal of Natural Medicines2017，15，4： | 12 |
| 7 | Resting heart rate control and prognosis in coronary artery disease patients with hypertension previously treated with bisoprolol:a subgroup analysis of the BISO-CAD study显示文摘Background:Resting heart rate(RHR)is considered as a strong predictor of total mortality and hospitalization due to heart failure in hypertension patients.Bisoprolol fumarate,a second-generation beta-adrenoreceptor blockers(β-blocker)is commonly prescribed drug to manage hypertension.The present study was to retrospectively evaluate changes in the average RHR and its association with cardiovascular outcomes in bisoprolol-treated coronary artery disease(CAD)patients from the CAD treated with bisoprolol(BISO-CAD)study who had comorbid hypertension.Methods::We performed ad-hoc analysis for hypertension sub-group of the BISO-CAD study(n=866),which was a phase IV,multination,multi-center,single-arm,observational study carried out from October 2011 to July 2015 across China,South Korea,and Vietnam.Multivariate regression analysis was used to identify factors associated with incidence of composite cardiac clinical outcome(CCCO),the results were presented as adjusted odds ratio(OR)along with 95%confidence interval(CI)and adjusted P value.Results::A total of 681 patients(mean age:64.77±10.33 years)with hypertension from BISO-CAD study were included in the analysis.Bisoprolol improved CCCOs in CAD patients with comorbid hypertension,with RHR<65 and<70 beats/min compared with RHR≥65 and≥75 beats/min,respectively,in the efficacy analysis(EA)set.In addition,it lowered RHR in both intent-to-treat(ITT)and EA groups after 6,12,and 18 months of treatment.Further,RHR 70 to 74 beats/min resulted in significantly higher risk of CCCOs EA set of patients(adjusted OR:4.34;95%CI:1.19-15.89;P=0.03).Also,events of hospitalization due to acute coronary syndrome were higher when RHR 69 to 74 beats/min compared to RHR<69 beats/min in ITT patients.Conclusion::Bisoprolol can effectively reduce RHR in Asian CAD patients with comorbid hypertension and hence,improve CCCO without affecting their blood pressure. | Yun-Dai Chen Xin-Chun Yang Vinh Nguyen Pham Shi-An Huang Guo-Sheng Fu Xiao-Ping Chen Binh Quang Truong Yu Yang Shao-Wen Liu Tian-Rong Ma Dong-Soo Kim Tae-hoon Kim | 2020 | Chinese Medical Journal2020，，10： | 10 |
| 8 | 曝气结合投加微生物法去除河水氨氮效果研究显示文摘指出了传统河道曝气技术能在短时间内提高水体溶解氧浓度、消除河道黑臭状态,在河道水质改善方面具有一定的可行性和优越性。基于此,尝试将投加微生物工程菌法与河道曝气技术有机结合,研发了去除河水中COD和NH_3-N的长期效果更好的组合工艺。以新河支流水生态修复项目为例,研究表明:投加微生物工程菌法与河道曝气技术对水去除COD、NH_3-N与增加微生物群落的效果显著。 | Tang Van Tai Tran Ngoc Binh Nguyen Nhu Anh PhanThi Hong Nhung | 2017 | 绿色科技2017，19，6： | 8 |
| 9 | Adsorptive hemofiltration for sepsis management: expert recommendations based on the Asia Pacific experience显示文摘To the Editor:In sepsis,bacterial endotoxins play a central role by inducing a dysregulated and exaggerated release of inflammatory mediators and cytokines,often described as the“cytokine storm”or“cytokinemia.”[1]Both endotoxins and cytokines have been implicated in the development of organ dysfunction,including acute kidney injury(AKI).[2]Removing circulating endotoxins and excess cytokines from the circulation restores chemotactic gradients,localizing the immune response to the principal site of infection and re-establishing a regulated immune response.[1,3]Therefore,using hemofilters with enhanced endotoxin and cytokine adsorptive properties may bring about additional therapeutic benefits compared with conventional continuous renal replacement therapy(CRRT)filters. | Ling Zhang Matthew Cove Binh G.Nguyen Nuttha Lumlertgul Kartik Ganesh Alfred Chan Giang T.H.Bui Chunwen Guo Junhua Li Songqiao Liu Mian Peng Kit W.Foong Jian Zhang Minmin Wang Jacques Goldstein Kai Harenski | 2021 | Chinese Medical Journal2021，，18： | 6 |
| 10 | Effect of Land Use Change on Runoff and Sediment Yield in Da River Basin of Hoa Binh province, Northwest Vietnam显示文摘The objective of this study was to assess runoff discharge and sediment yield from Da River Basin in the Northwest of Vietnam using Soil and Water Assessment Tools(SWAT) model.The SWAT model was calibrated and validated using the observed monthly stream flows and sediment yield at selected gauging stations.The results indicated that SWAT generally performs well in simulating runoff and sediment yield according to Nash-Sutcliffe efficiency(NSE), Observation's standard deviation ratio(RSR), and percent bias(PBIAS) values.For runoff, the values of NSE, RSR, and PBIAS were 0.98,0.02, and 3.69 during calibration period and 0.99,0.01, and 1.56 during validation period, respectively.For sediment yield, the efficiency was lower than the value of NSE, RSR, and PBIAS during calibration period were 0.81, 0.19, and-4.14 and 0.84, 0.16, and-2.56 during validation period, respectively.The results of the study indicated that the vegetation status has a significant impact on runoff and sediment yield.Changes in land use type between 1995 and2005 from forest to field crop and urban strongly contributed to increasing the average annual runoff from 182.5 to 342.7 mm and sediment yield from101.3 to 148.1 ton-1 ha.Between 2005 and 2010, adecrease of both runoff(from 342.7 to 167.6 mm) and sediment yield(from 148.1 to 74.0 ton-1 ha) was due to the expansion of forested area and application of soil conservation practices.The results of this study are important for developing soil and water conservation programs, extending future SWAT modelling studies and disseminating these results to other regions in Vietnam. | NGO Thanh Son NGUYEN Duy Binh Rajendra Prasad SHRESTHA | 2015 | Journal of Mountain Science2015，12，4： | 6 |
| 11 | Multilevel Threshold Based Image Denoising in Curvelet Domain显示文摘In this paper, we propose a multilevel thresholding technique for noise removal in curvelet transform domain which uses cycle-spinning. Most of uncorrelated noise gets removed by thresholding curvelet coeffcients at lowest level, while correlated noise gets removed by only a fraction at lower levels, so we used multilevel thresholding on curvelet coe?cients. The threshold in the proposed method depends on the variance of curvelet coeffcients, the mean and the median of absolute curvelet coeffcients at a particular level which makes it adaptive in nature. Results obtained for 2-D images demonstrate an improved performance over other recent related methods available in literature. | Nguyen Thanh Binh Ashish Khare | 2010 | Journal of Computer Science & Technology2010，25，3： | 6 |
| 12 | Acute liver injury induced by weight-loss herbal supplements显示文摘We report three cases of patients with acute liver injury induced by weight-loss herbal supplements. One patient took Hydroxycut while the other two took Herbalife supplements. Liver biopsies for all patients dem onstrated f indings consistent with drug-induced acute liver injury. To our knowledge, we are the fi rst instit ute to report acute liver injury from both of these two typ es of weight-loss herbal supplements together as a case series. The series emphasizes the importance of taking a cautious approach when consuming herbal supp lements for the purpose of weight loss. | Gary C Chen Vivek S Ramanathan David Law Pauline Funchain George C Chen Samuel French Boris Shlopov Viktor Eysselein David Chung Sonya Reicher Binh V Pham | 2010 | World Journal of Hepatology2010，2，11： | 5 |
| 13 | Interactions between metal ions and the biopolymer in activated sludge: quantification and effects of system pH value显示文摘 | Yun Zhou Siqing Xia Binh T. Nguyen Min Long Jiao Zhang Zhiqiang Zhang | 2017 | Frontiers of Environmental Science & Engineering2017，11，1： | 4 |
| 14 | Comparative study between wear of uncoated and TiAIN-coated carbide tools in milling of Ti6AI4V显示文摘 | M. S. Uddin Binh Pham Ahmed Sarhan Animesh Basak Alokesh Pramanik | 2017 | Advances in Manufacturing2017，5，1： | 4 |
| 15 | 越南西北部大象山超高温变质岩的发现及其区域构造意义显示文摘越南西北部大象山群孔兹岩系中发育一套含刚玉+尖晶石+石榴石+夕线石组合的富铝岩石块体,它们呈透镜状包体形式赋存于孔兹岩系内。岩石中刚玉+尖晶石+石榴石+夕线石组合的发育指示岩石经历了超高温变质作用的改造。其中尖晶石和石英的共生组合表明了变质温度高于900℃,而利用岩石退变质矿物组合中的黑云母-石榴石温度计,黑云母-斜长石-石榴石-石英组合温度-压力计估算的变质温度压力条件分别为879~917℃、0.90~0.94GPa。岩石中的早期刚玉+夕线石的组合的存在说明岩石变质作用已经从高角闪岩相进入到了麻粒岩相;而峰期变质矿物组合尖晶石+石英的出现,指示了变质温度高于900℃的超高温变质作用。另一方面,退变质过程中钛铁矿的发育表明岩石经历了快速抬升降压的过程。变质作用的P-T轨迹分析揭示出岩石经历了早期同步升温增压后的快速增温达到峰期条件,后经历快速等温减压过程。这种温压条件的变化与板块会聚过程中由于俯冲板片的断离而使软流圈上涌造成热异常的温压条件变化基本一致。通过对超高温变质岩石进行锆石SIMSU-Pb测年获得的结果大于58Ma,推测这次超高温变质与喜马拉雅运动中印度与欧亚大陆的初期会聚-碰撞作用相关。 | 吴虎峻 刘俊来 TRAN My Dung NGUYEN Quang Luat PHAM Binh 吴文彬 陈文 张招崇 | 2011 | 岩石学报2011，27，9： | 4 |
| 16 | 农田生态沟渠效能研究显示文摘传统混凝土沟渠主要使用浆砌石、钢筋混凝土等材料建造成排水沟渠,难以有效去除农田污水中的富营养化,引起河道污染~[1]。本实验在调查太湖运河沿岸农田的污染情况的基础上,设计并建造复合生态沟渠示范工程,然后根据季节差异种植复合的植物。通过观察植物生长情况研究生态沟渠的植生价值,检测生态沟渠的水质变化情况以检验农田污水富营养化的去除效能。 | Tang Van Tai Tran Ngoc Binh Tang Thi Thanh Sang Le Hong Hanh | 2017 | 黑龙江生态工程职业学院学报2017，30，5： | 3 |
| 17 | Staining for p53 and Ki-67 increases the sensitivity of EUS-FNA to detect pancreatic malignancy显示文摘AIM:To investigate whether tumor marker staining can improve the sensitivity of endoscopic ultrasound-guided fine needle aspiration(EUS-FNA)to diagnose pancreatic malignancy. METHODS:Patients who underwent EUS-FNA were retrospectively identified.Each EUS-FNA specimen was evaluated by routine cytology and stained for tumor markers p53,Ki-67,carcinoembryonic antigen(CEA) and CA19-9.Sensitivity,specificity,positive and negative predictive values(PPV and NPV),and positive and negative likelihood ratios(PLR and NLR)were calculated in order to evaluate the performance of each test to detect malignancy. RESULTS:Sixty-one specimens had complete sets of stains,yielding 49 and 12 specimens from pancreatic adenocarcinomas and benign pancreatic lesions due to pancreatitis,respectively.Cytology alone had sensitivity and specificity of 41%and 100%to detect malignancy, respectively.In 46%of the specimens,routine cytology alone was deemed indeterminate.The addition of either p53 or Ki-67 increased the sensitivity to 51%and 53%,respectively,with perfect specificity,PPV and PLR (100%,100%and infinite).Both stains in combination increased the sensitivity to 57%.While additional staining with CEA and CA19-9 further increased the sensitivity to 86%,the specificity,PPV and PLR were significantly reduced(at minimum 42%,84%and 1,respectively).Markers in all combinations performed poorly as a negative test(NPV 26%to 47%,and NLR 0.27 and 0.70).CONCLUSION:Immunohistochemical staining for p53 and Ki-67 can improve the sensitivity of EUS-FNA to diagnose pancreatic adenocarcinoma. | Alexander W Jahng Sonya Reicher David Chung Donna Varela Rahul Chhablani Anil Dev Binh Pham Jose Nieto Rose J Venegas Samuel W French Bruce E Stabile Viktor E Eysselein | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，11： | 3 |
| 18 | 辐射变暗和透明度降低共同加剧湖泊水下变黑显示文摘人类活动和气候变化造成到达地表太阳辐射降低(即辐射变暗)和水体透明度下降,两者共同作用深刻影响到水生生态系统水下光环境.全国116个太阳辐射观测站和839个日照时数观测站长期观测数据显示,2000年之后年均地表太阳辐射和日照时数比20世纪60年代分别下降了5.8%和7.9%,呈现显著下降趋势.与此同时,20世纪80年代和2006~2010年两次全国湖泊调查和历史文献数据分析发现,170个湖泊透明度平均值由1995年之前的1.80±2.19 m下降到2005年之后的1.28±1.82 m,遥感反演发现641个面积大于10 km2的湖泊透明度平均值由1985~1990年的1.26±0.62 m降低到2005~2010年的1.14±0.66 m.辐射变暗和透明度降低共同造成全国湖泊平均真光层深度范围内可利用的光合有效辐射量降低10%左右,并且透明度降低对湖泊水下光合有效辐射降低的贡献超过80%.文献综合分析进一步显示,全球湖库、海湾和近海水体均普遍存在透明度下降,水下变暗甚至变黑的事实,其势必深刻影响到水生生态系统各种物理、化学和生物过程以及生物多样性、生态系统服务功能和服务价值. | 张运林 秦伯强 施坤 张毅博 邓建明 Martin Wild Lin Li 周永强 姚晓龙 刘淼 朱广伟 张路 Binhe Gu Justin D.Brookes | 2020 | Science Bulletin2020，65，19： | 3 |
| 19 | Smart ring resonator–based sensor for multicomponent chemical analysis via machine learning显示文摘We demonstrate a smart sensor for label-free multicomponent chemical analysis using a single label-free ring resonator to acquire the entire resonant spectrum of the mixture and a neural network model to predict the composition for multicomponent analysis. The smart sensor shows a high prediction accuracy with a low rootmean-squared error ranging only from 0.13 to 2.28 mg/m L. The predicted concentrations of each component in the testing dataset almost all fall within the 95% prediction bands. With its simple label-free detection strategy and high accuracy, the smart sensor promises great potential for multicomponent analysis applications in many fields. | ZHENYU LI HUI ZHANG BINH THI THANH NGUYEN SHAOBO LUO PATRICIA YANG LIU JUN ZOU YUZHI SHI HONG CAI ZHENCHUAN YANG YUFENG JIN YILONG HAO YI ZHANG AI-QUN LIU | 2021 | Photonics Research2021，9，2： | 3 |
| 20 | Recent Rapid Decline of the Arctic Winter Sea Ice in the Barents–Kara Seas Owing to Combined Effects of the Ural Blocking and SST显示文摘This study investigates why the Arctic winter sea ice loss over the Barents–Kara Seas(BKS) is accelerated in the recent decade. We first divide 1979–2013 into two time periods: 1979–2000(P1) and 2001–13(P2), with a focus on P2 and the difference between P1 and P2. The results show that during P2, the rapid decline of the sea ice over the BKS is related not only to the high sea surface temperature(SST) over the BKS, but also to the increased frequency,duration, and quasi-stationarity of the Ural blocking(UB) events. Observational analysis reveals that during P2, the UB tends to become quasi stationary and its frequency tends to increase due to the weakening(strengthening) of zonal winds over the Eurasia(North Atlantic) when the surface air temperature(SAT) anomaly over the BKS is positive probably because of the high SST. Strong downward infrared(IR) radiation is seen to occur together with the quasi-stationary and persistent UB because of the accumulation of more water vapor over the BKS. Such downward IR favors the sea ice decline over the BKS, although the high SST over the BKS plays a major role. But for P1, the UB becomes westward traveling due to the opposite distribution of zonal winds relative to P2, resulting in weak downward IR over the BKS. This may lead to a weak decline of the sea ice over the BKS. Thus, it is likely that the rapid decline of the sea ice over the BKS during P2 is attributed to the joint effects of the high SST over the BKS and the quasi-stationary and long-lived UB events. | Binhe LUO Yao YAO | 2018 | Journal of Meteorological Research2018，32，2： | 3 |
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