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303篇 您的检索式:作者名="Bennett Y"
    题名 作者 年代 出处 被引量
1美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) 2012中华神经科杂志2012,45,5:22
2青少年甘油磷酸胆碱代谢和心血管病的危险因素:一项队列研究显示文摘甘油磷酸胆碱(glycerophosphocholine,GPC)代谢物可调节动脉粥样硬化,从而导致心血管病风险。临床前期心血管病可能从青春期就开始。研究人员应用靶向血清脂质组学鉴定一组新的GPC,并测试在青春期时这些GPC中的任何一种是否与心血管病传统危险因子,如过量内脏脂肪、升高的血压、胰岛素抵抗和致动脉粥样硬化血脂异常相关。Syme C Czajkowski S Shin J Abrahamowicz M Leonard G Perron M Richer L Veillette S Gaudet D Strug L Wang Y Xu H Taylor G Paus T Bennett S Pausova Z 刘莉 叶鹏 2016中华高血压杂志2016,24,10:3
3Adducin: structure, function and regulation 显示文摘Matsuoka Y Li X Bennett V 2000Cell Mol Life Sci2000,57,6:1
4Metabolic engineering of Escherichia coli to enhance recombinant protein production through acetate reduction显示文摘Aristidou A A San K Y Bennett G N 1995Biotechnol Prog1995,11,:1
5Robust electrical spin injection into a semiconductor heterostructure显示文摘Jonker B Park Y Bennett B 0,,12:1
6A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man显示文摘Bennett G J Xie Y K 1988Pain1988,33,1:1
7Float polishing of optical materials显示文摘BENNETT J M SHAFFER J J SHIBANO Y 1987Appl Opt1987,26,4:1
8A peripheral mononeuropathy in rat that pro- duces disorders of pain sensation like those seen in man 显示文摘Bennett G J Xie Y K 1988Pain1988,33,1:1
9A peripheral mononeuropathy in rat that produces disorders of pain sensationlike those seen in man显示文摘Bennett G J Xie Y K 1988Pain1988,33,1:1
10Photoreceptor cell rescue in retinal degeneration (rd) mice by in vivo gene therapy显示文摘Bennett J Tanabe T Sun D Zeng Y Kieldbye H Gouras P 1996Nat Med1996,2,6:1
11Chronic ulcers of the skin显示文摘Bennett L Lee B Y 1985New Youk:MeGraw HiU1985,,:1
12Enhanced lycopene productivity by manipulation of carbon flow to isopentenyl diphosphate in Escherichia eoli显示文摘Vadali R V Fu Y Bennett G N 2005Biotechnol Progr2005,21,5:1
13Effect of carbon sources differing in oxidation state and transport route on succinate production in metabolically engineered Escherichia coli显示文摘Lin H Bennett G N San K Y 2005Journal of Industrial Microbiology and Biotechnology2005,32,3:1
14The functional effects of physical interactions among Toll-like receptors 7, 8, and 9 显示文摘Wang J Shao Y Bennett TA 2006J Biol Chem2006,281,37:1
15A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man 显示文摘Bennett G J Xie Y K 1988Pain1988,33,1:1
16Mild cognitive impairment: Risk of Alzheimer disease and rate of cognitive decline显示文摘P A. Boyle R S. Wilson N T. Aggarwal Y Tang D A. Bennett 2006Neurology2006,,3:1
17Intracellular interleukin-1 receptor 2 bind- ing prevents cleavage and activity of interleukin-la, controlling necrosis-induced sterile inflammation 显示文摘Zheng Y Humphry M Maguire J J Bennett M R Clarke M C 2013Immunity2013,38,:1
18Genetic reconstruction of the aerobic central metabolism in Escherichia coli for the absolute aerobic production of succinate显示文摘Lin H Bennett G N San K Y 2005Biotechnol Bioeng2005,89,2:1
19The introduc tion of P4 substituted 1-methyleyclohexyl groups into Bo- ceprevir:a change in direction in the search for a second generation HCV NS3 protease inhibitor 显示文摘Bennett F Huang Y and Njoroge F G 2010Bioorg Med Chem Lett2010,20,:1
20Regulation of microsomal and cytosolic glutathione S-transferase activities by S-nitrosylation显示文摘 Toader V Bennett BM 2002Biochem Pharmacol2002,63,8:1
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