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192篇 您的检索式：作者名="Benedict S"

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	题名	作者	年代	出处	被引量
1	Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice显示文摘AIM:To investigate the therapeutic effect of Schistosoma mansoni(S.mansoni) soluble worm proteins on gastrointestinal motility disturbances during experimental colitis in mice. METHODS:Colitis was induced by intrarectal injection of trinitrobenzene sulphate(TNBS) and 6 h later,mice were treated ip with S.mansoni proteins.Experiments were performed 5 d after TNBS injection.Inflammationwas quantified using validated inflammation parameters. Gastric emptying and geometric center were measured to assess in vivo gastrointestinal motility.Peristaltic activity of distal colonic segments was studied in vitro using a modified Trendelenburg set-up.Cytokine profiles of T-lymphocytes isolated from the colon were determined by real time reverse transcriptase-polymerase chain reaction. RESULTS:Intracolonic injection of TNBS caused severe colitis.Treatment with S.mansoni proteins significantly ameliorated colonic inflammation after 5 d.TNBS did not affect gastric emptying but significantly decreased the geometric center and impaired colonic peristaltic activity 5 d after the induction of colitis.Treatment with S.mansoni proteins ameliorated these in vivo and in vitro motility disturbances.In addition,TNBS injection caused a downregulation of effector T cell cytokines after 5 d,whereas a S.mansoni protein effect was no longer observed at this time point. CONCLUSION:Treatment with S.mansoni proteins attenuated intestinal inflammation and ameliorated motility disturbances during murine experimental colitis.	Nathalie E Ruyssers Benedicte Y De Winter Joris G De Man Natacha D Ruyssers Ann J Van Gils Alex Loukas Mark S Pearson Joel V Weinstock Paul A Pelckmans Tom G Moreels	2010	World Journal of Gastroenterology2010，16，6：	11
2	Identification of promoter elements responsible for the regulation of MDR1 from Candida albicans,a major facilitator transporter involved in azole resistance显示文摘	Benedicte R Zuzana K Dominique S	2006	Microbiology2006，152，：	1
3	Activation of long-term synaptic plasticity efuses suppression of epileptiform activity in rat hippocampal slices显示文摘	Benedict C Albensi GA Erln S	2004	Brain Res2004，1998，1：	1
4	Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: a report from the Studies of Left Ventricular Dysfunction (SOLVE) 显示文摘	Torre-Amione G Kapadia S Benedict C	1996	J Am Coll Cardiol1996，27，：	1
5	Modeling theperformance of a solar pond as a source of thermal energy显示文摘	Rubin H Benedict B A Bachu S	1984	Solar Energy1984，32，6：	1
6	CLN3 ,the protein associated with batten disease : structure, function and localization 显示文摘	Phillips S N Benedict J W Weimer J M	2005	J Neurosci Res2005，79，5：	1
7	Proinflammatory cytokine levels in patients with depressed leftventricular ejection fraction : a report from the Studies on LeftVentricular Dysfunction (SOLVD) 显示文摘	TORRE-AMIONE G KAPADIA S BENEDICT C	1996	J Am Coll Cardiol1996，27，5：	1
8	Lysophosphatidylcholine potentiates the mitogenic effect of various vasoactive compounds on rabbit aortic smooth muscle cell显示文摘	Watanabe T Koba S Katagiri T Pakala R Benedict CR	2002	Jpn Heart J2002，43，：	1
9	Proinflammatory cytokine levels in patients wth depressed left ventricular ejection fraction: A report from the studies of left veutricular dysfunction ( SOLVD ) 显示文摘	Torre- Amione G Kapadia S Benedict C	1996	J Am Coll Cardiol1996，27，：	1
10	Intranasal insulinenhances postprandial thermogenesis and lowers postprandialserum insulin levels in healthy men显示文摘	Benedict C Brede S Schioth H B	2011	Diabetes2011，60，1：	1
11	The role of the Himalayas and the Ti-betan Plateau within the Asian mons oon system 显示文摘	BOLLASINA M BENEDICT S	2004	Bulletin of the American Meteorological Society2004，85，7：	1
12	Rotation-vibration spec- tra of deuterated water vapor显示文摘	Benedict W S Gailar N Plyler E K	1956	The Journal of Chemical Physics1956，24，6：	1
13	The lung as an alternative route of delivery for insulin in controlling postprandial glucose levels in patients with diabetes显示文摘	BENEDICT G W DOBS A S	1998	Chest1998，114，9：	1
14	The CBFI-de- pendent low temperature signalling pathway,regulon and increase in freeze tolerance are conserved in Populus spp 显示文摘	Benedict C Skinner J S Meng R	2006	Plant Cell & Environment2006，29，7：	1
15	Essential role for caspase-8 in Toll-like receptors and NF kappa B signaling显示文摘	Benedicte L Leonardo S Nicolas B	2007	Biol Chem2007，282，：	1
16	Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction:a report from the studies of left ventricular dysfunction (SOLVD)显示文摘	TORRE-AMIONE G KAPADIA S BENEDICT C	1996	J Am Coll Cardiol1996，27，：	1
17	Prevention of congestive heart failure and management of asymptomatic left ventricular dysfuncion 显示文摘	Mckelvie RS Benedict CR Yusuf S	1999	BMJ1999，318，：	1
18	Stereotactic body radiation therapy: the report of AAPM Task Group 101显示文摘	BENEDICT S H YENICE K M FOLLOWILL D	2010	Med Phys2010，37，8：	1
19	Expression and segregation of genes Cry1A insecticidal proteins in cotton 显示文摘	SACHS E S BENEDICT J H STELLY D M et at	1998	Crop Sci1998，38，：	1
20	Scheduling of scientific workflows using simulated annealing algorithm for computational grids 显示文摘	BENEDICT S VASUDEVAN V	2007	International Journal of Soft Computing2007，2，5：	1

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