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| 1 | OPC UA TSN:新工业数据通讯解决方案之研究显示文摘在工业自动化系统集成中,不同厂商一般都有自己的数据通讯标准和协议。目前工业数据通讯领域由基于以太网的各类现场总线系统主导,虽然它们有着相似的要求和细分市场,但是它们的实施和生态系统差别却很大。价值链中的利益相关者通常在其特定技术的决策方面并不完全一致,因此,终端客户和设备制造商不得不购买和掌握诸多产品和技术,这就大大提高了使用成本。时间敏感网络TSN与OPC UA的结合,能实现从现场层、控制层、管理层直到云端的数据通讯。OPC UA TSN作为独立于某一特定厂商的后继技术,将IT和OT无缝融合到现场总线项目中,可以获得良好的适用性并实现更高水平的自动化配置。我们发现,通过选择正确的一系列功能特性,它能够满足今天和未来的工业通讯要求,同时在中期利用标准以太网硬件的成本优势。由AVB演变而来的TSN网络基础结构同时能够承载各类工业通信,从硬实时到尽力服务,同时保持每种方法的独特属性。OPC UA是针对嵌入式应用的OPC通讯标准的重大发展。被描述为发布/订阅的最新进展则更进一步,旨在为嵌入式设备在较小空间内优化性能。它增加了用于描述数据的源模型,以及用于交换和浏览信息的通讯基础结构。此外,OPC UA还带有一个内置的安全模型,可以根据即将出台的标准如IEC 62443来帮助实施安全系统。我们预计,OPC UA TSN将很快将自身作为工业自动化领域内的游戏规则变革者,成为从传感器到云端建立全面的通讯基础结构的首要也是唯一的候选对象。 | Dietmar Bruckner | 2018 | 智慧工厂2018，0，5： | 3 |
| 2 | Liver stiffness reversibly increases during pregnancy and independently predicts preeclampsia显示文摘AIM To study liver stiffness(LS) during pregnancy and its association with complications during pregnancy.METHODS In this observational, diagnostic study, 537 pregnant women were prospectively enrolled at the Department of Obstetrics and Gynecology, University hospital Heidelberg and Salem Medical Center. LS was measured using the Fibroscan device(Echosens, Paris) in all women and in 41 cases 24 h after delivery. Clinical and morphological data were recorded and abdominal ultrasound and standard laboratory tests were performed. No complications were observed in 475 women(controls) while preeclampsia and intrahepatic cholestasis of pregnancy(ICP) developed in 22 and 40 women, respectively.RESULTS In controls, LS increased significantly from initially 4.5 ± 1.2 kPa in the second trimester to 6.0 ± 2.3 kPa(P < 0.001) in the third trimester. In the third trimester, 41% of women had a LS higher than 6 kPa. Elevated LS in controls was significantly correlated with alkaline phosphatase, leukocytes, gestational age and an increase in body weight and body mass index(BMI). In women with pregnancy complications, LS was significantly higher as compared to controls(P < 0.0001). Moreover, in multivariate analysis, LS was an independent predictor for preeclampsia with an odds ratio of 2.05(1.27-3.31) and a cut-off value of 7.6 kPa. In contrast, ICP could not be predicted by LS. Finally, LS rapidly decreased in all women within 24 h after delivery from 7.2 ± 3.3 kPa down to 4.9 ± 2.2 kPa(P < 0.001).CONCLUSION During pregnancy, LS significantly and reversibly increases in the final trimester of pregnant women without complications. In women with preeclampsia, LS is significantly elevated and an independent noninvasive predictor. | Franziska J Ammon Anna Kohlhaas Omar Elshaarawy Johannes Mueller Thomas Bruckner Christof Sohn Gabriele Fluhr Herbert Fluhr Sebastian Mueller | 2018 | World Journal of Gastroenterology2018，24，38： | 2 |
| 3 | Is Preoperative Chemotherapy Followed by Surgery the Appropriate Treatment for Signet Ring Cell Containing Adenocarcinomas of the Esophagogastric Junction and Stomach?显示文摘 | Ulrike Heger Susanne Blank Christiane Wiecha Rupert Langer Wilko Weichert Florian Lordick Thomas Bruckner Martin Dobritz Maria Burian Christoph Springfeld Lars Grenacher J?rg-Rüdiger Siewert Markus Büchler Katja Ott | 2014 | Annals of Surgical Oncology2014，，5： | 2 |
| 4 | Replacement of the proximal humerus with MUTARS tumor endoprostheses显示文摘 | P. Raiss S. Kinkel U. Sauter T. Bruckner B. Lehner | 2009 | European Journal of Surgical Oncology2009，，4： | 2 |
| 5 | Public policy modeling of distributed energy technologies : strategies, attributes, and challenges 显示文摘 | BRUCKNER T MORRISON R WITTMANN T | 2005 | Ecological Economics2005，54，23： | 1 |
| 6 | Mucin-associated sialosyl-Tn antigen expression in gastric cancer correlates with an adverse outcome显示文摘 | Werther JL MacMurray SR Bruckner H | 1994 | Br J Cancer1994，69，3： | 1 |
| 7 | Serum skeletal troponin I in inflammatory muscle disease: relation to creatine kinase, CKMB and cardiac troponin I 显示文摘 | Kiely PDW Bruckner FE Nisbet JA | 2000 | Ann Rheum Dis2000，59，： | 1 |
| 8 | Use of an ex vivo ATP luminescence assay to direct chemotherapy for recurrent ovarian cancer显示文摘 | Kurbacher CM Cree IA Bruckner HW | 1998 | Anticancer Drugs1998，9，1： | 1 |
| 9 | Resistance behavior and inter-diffusion of layered Cu-Ni-Cr films显示文摘 | Bruckner W Schumann J Baunack S | 1995 | Thin Solid Films1995，258，12： | 1 |
| 10 | Trichloroethylene risk assessment: A review and commentary 显示文摘 | Jollow D J Bruckner J V McMillan DC | 2009 | Crit Rev Toxicol2009，39，9： | 1 |
| 11 | Instant volume visualization using maximum intensity difference accumulation 显示文摘 | Bruckner S Gr?ller M E | 2009 | Computer Graphic Forum2009，28，3： | 1 |
| 12 | Sacral resection and reconstruction for tumors and tumor-like conditions 显示文摘 | Randall RL Bruckner J Lloyd C | 2005 | Orthopedics2005，28，3： | 1 |
| 13 | Renal cell carcinoma,metastatic to the left ventricle显示文摘 | Aburto J Bruckner BA Blackmon SH | 2009 | Tex Heart Inst J2009，36，1： | 1 |
| 14 | A review of analytical methods for the determination of trichloroethylene and its major metabolites chloral hydrate, trichloroacetic acid and dichloroacetic acid 显示文摘 | Delinsky AD Bruckner JV Bartlett MG | 2005 | Biomedical Chromatography2005，19，8： | 1 |
| 15 | Phase I and Ⅱ studies of intravenous Rexin-G as monotherapy for stage IVb gem- citabine-resistant pancreatic cancer显示文摘 | BRUCKNER H CHAWLA SP CHUA CS | 2010 | J Clin Oncol2010，28，15： | 1 |
| 16 | Enhancing depth-perception with flexible volumetric halos显示文摘 | Bruckner S GrOller M E | 2007 | IEEE Transactions on Visualization and Computer Graphics2007，13，6： | 1 |
| 17 | Intestinal microvascular malformations and congenital asplenia in an adolescent possibly expanding the phenotype of Ivemark syndrome显示文摘 | Wurfel C Bruckner S Aust DE | 2011 | Eur J Gastro- enteml Hepatol2011，23，12： | 1 |
| 18 | Thin wafer-level camera lenses inspired by insect compound eyes显示文摘 | BRUCKNER A DUPARRE J LEITEL R | 2010 | Optics Express2010，18，24： | 1 |
| 19 | Oral toxicity of carbon tetrachloride : acute, subacute and subchronic studies in rats显示文摘 | Bruckner J V MacKenzie W F Muralidhara S l | 1986 | Fundamental and Applied Toxicology1986，，6： | 1 |
| 20 | Impact of atopic skin diathesis on occupational skin disease inci- dence in a working population显示文摘 | Dickel H Bruckner T M Schmidt A | 2003 | J Invest Dermatol2003，121，1： | 1 |
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