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| 1 | Giant hepatic extra-gastrointestinal stromal tumor treated with cytoreductive surgery and adjuvant systemic therapy:A case report and review of literature显示文摘BACKGROUND Primary extra-gastrointestinal stromal tumors(E-GIST)of the liver are rare.The clinical presentation may range from asymptomatic to bleeding or manifestations of mass effect.Oncologic surgery followed by adjuvant therapy with imatinib is the standard of care.However,under specific circumstances,a cytoreductive approach may represent a therapeutic option.We describe herein the case of an 84-year-old woman who presented with a tender,protruding epigastric mass.Abdominal computed tomography scan revealed a large,heterogeneous mass located across segments III,IV,V,and VIII of the liver.The initial approach was transarterial embolization of the tumor,which elicited no appreciable response.Considering the large size and central location of the tumor and the advanced age of the patient,non-anatomic complete resection was indicated.Due to substantial intraoperative bleeding and hemodynamic instability,only a near-complete resection could be achieved.Histopathology and immunohistochemical staining confirmed the diagnosis of primary E-GIST of the liver.Considering the risk/benefit ratio for therapeutic options,debulking surgery may represent a strategy to control pain and prolong survival.CASE SUMMARY Here,we present a case report of a patient diagnosed with E-GIST primary of the liver,which was indicated a cytoreductive surgery and adjuvant therapy with imatinib.CONCLUSION E-GIST primary of the liver is a rare conditional,the treatment is with systemic therapy and total resection surgery.However,a cytoreductive surgery will be necessary when a complete resection is no possible. | Michel Ribeiro Fernandes Caroline Lorenzoni Almeida Ghezzi Tomaz J M Grezzana-Filho Flávia Heinz Feier Ian Leipnitz Aljamir Duarte Chedid Carlos Thadeu Schmidt Cerski Marcio Fernandes Chedid Cléber RositoPinto Kruel | 2021 | World Journal of Gastrointestinal Surgery2021，13，3： | 3 |
| 2 | Xanthogranulomatous cholecystitis resembling carcinoma with extensive tumorous infiltration of the liver and colon显示文摘 | Jürgen Pinocy Antje Lange Claudius K?nig Edwin Kaiserling Horst D. Becker Stefan M. Kr?ber | 2003 | Langenbeck’s Archives of Surgery2003，，1： | 2 |
| 3 | Iris-fixated anterior chamber phakic in- traocular lens for myopia moves posteriorly with mydriasis显示文摘 | Cruysberg LP Doors M Berendschot TT De Brabander J We- bers CA Nuijts RM | 2009 | J Refract Surg2009，25，4： | 1 |
| 4 | Overview of Radiolocation in CDMA Cellular Systems显示文摘 | James J Caffery Gordon L Stüber | 1998 | IEEE Communications Magazine1998，，4： | 1 |
| 5 | Overview of Radiolocation in CDMA Cellular Systems显示文摘 | CAFFERY J ST(U)BER G | 1998 | IEEE Communication Magazine1998，36，4： | 1 |
| 6 | Degenerative lesions in the articular cartilage after meniscectomy:preliminary experimentalstudy in dogs显示文摘 | BER JON J J MUNUERA L CALVO M | 1991 | J Trauma1991，31，： | 1 |
| 7 | Long-Term Propensity Score–Matched Comparison of Percutaneous Closure of Patent Foramen Ovale With Medical Treatment After Paradoxical Embolism显示文摘 | Andreas Wahl Peter Jüni Marie-Luise Mono Bindu Kalesan Fabien Praz Laura Geister Lorenz R?ber Krassen Nedeltchev Heinrich P. Mattle Stephan Windecker Bernhard Meier | 2012 | Circulation2012，，6： | 1 |
| 8 | A highly at- tenuated recombinant human respiratory syncytial virus lacking the G protein induces long-lasting protection in cotton rats 显示文摘 | Widjojoatmodjo MN Boes J van Bers M eta/ | 2010 | Virol J2010，7，1： | 1 |
| 9 | Analysis and design of interleaver mappings for iteratively decoded BICM 显示文摘 | Tan J Stüber G L | 2005 | IEEE Transactions on Wireless Communications2005，4，2： | 1 |
| 10 | Xanthogranulomatous cholecystitis resembling carcinoma with extensive tumorous infiltration of the liver and colon显示文摘 | Jürgen Pinocy Antje Lange Claudius K?nig Edwin Kaiserling Horst D. Becker Stefan M. Kr?ber | 2003 | Langenbeck’s Archives of Surgery2003，，1： | 1 |
| 11 | Changing perspective on immunization a-gainst influenza显示文摘 | Ber E J Ian C B | 2007 | Vaccine2007，25，16： | 1 |
| 12 | CaMKH in myocar- dial hypertrophy and heart failure显示文摘 | Anderson M E Brown J H Bers D M | 2011 | J Mol Cell Cardiol2011，51，4： | 1 |
| 13 | Overview of Radiolocation in CDMA Cellular Systems显示文摘 | Gordon Stüber L | 1998 | IEEE Communications Magazine1998，，4： | 1 |
| 14 | Effect of starvation and trauma on gastrointestinal flora and bacterial translocation 显示文摘 | Deitch EA Winterton J Ber R | 2003 | Arch Surg2003，132，12： | 1 |
| 15 | 心电图预激表现与心血管病和死亡风险的关系:哥本哈根心电图研究结果显示文摘大部分心室预激患者临床发病过程中的心电图资料来源于三级医疗中心。为了调查患有心电图预激的初级保健人群的长期预后,来自丹麦哥本哈根Rigshospitalet心脏中心分子心脏病学实验室的研究人员在2001—2011年收集了328638例初级保健患者的电子心电图数据,确定了310例心电图显示预激(年龄8~85岁)的个体。并从丹麦全国注册管理机构获取关于患者药物、合并症和临床结局的资料。随访中位数为7.4(四分位间距4.6~10.3)年。 | 刘莉 叶鹏 Skov MW Rasmussen PV Ghouse J Hansen SM Graff C Olesen MS Pietersen A Torp-Pedersen C HaunsS Kφber L Svendsen JH Holst AG Nielsen JB | 2017 | 中华高血压杂志2017，25，10： | 1 |
| 16 | Why does performance persis- tence vary among closed-end funds?显示文摘 | Bers M K Madura J | 2000 | Journal of Financial Services Research2000，17，： | 1 |
| 17 | Auto- matic case acquisition from texts for process--oriented case- based reasoning 显示文摘 | DUFOUR-LUSSIER V LE BER F LIEBER J | 2014 | Information Systems2014，40，1： | 1 |
| 18 | Antiarrhythmic effect of carvedilol after acute myocardial infarction:results of the Carvedilol Post-Infarct Survival Control in Left Ventricular Dysfunction (Capricorn) trial显示文摘 | McMurray J K?ber L Robertson M | 2005 | J Am Coll Cardiol2005，45，4： | 1 |
| 19 | Task complexity enhances response inhibition deficits in childhood and adolescent attention-deficit/hyperactivity disorder:a meta-regression analysis显示文摘 | Huizenga HM van Bers BM CW Plat J | 2009 | Biol Psychiatry2009，65，1： | 1 |
| 20 | Diffusion-weighted whole-body MR imaging with background body signal suppression: a feasibility study at 3.0 Tesla显示文摘 | Petra Mürtz Carsten Krautmacher Frank Tr?ber Jürgen Gieseke Hans H. Schild Winfried A. Willinek | 2007 | European Radiology2007，，12： | 1 |
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