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| 1 | Impact of laparoscopic surgery training laboratory on surgeon's performance显示文摘Minimally invasive surgery has been replacing the open standard technique in several procedures. Similar or even better postoperative outcomes have been described in laparoscopic or robot-assisted procedures when compared to open surgery. Moreover, minimally invasive surgery has been providing less postoperative pain, shorter hospitalization, and thus a faster return to daily activities. However, the learning curve required to obtain laparoscopic expertise has been a barrier in laparoscopic spreading. Laparoscopic surgery training laboratory has been developed to aid surgeons to overcome the challenging learning curve. It may include tutorials, inanimate model skills training(box models and virtual reality simulators), animal laboratory, and operating room observation. Several different laparoscopic courses are available with specific characteristics and goals. Herein, we aim to describe the activities performed in a dry and animal-model training laboratory and to evaluate the impact of different kinds of laparoscopic surgery training courses on surgeon's performance. Several tasks are performed in dry and animal laboratory to reproduce a real surgery. A short period of training can improve laparoscopic surgical skills, although most of times it is not enough to confer laparoscopic expertise for participants. Nevertheless, this short period of training is able to increase the laparoscopic practice of surgeons in their communities. Full laparoscopic training in medical residence or fellowship programs is the best way of stimulating laparoscopic dissemination. | Fabio C M Torricelli Joao Arthur B A Barbosa Giovanni S Marchini | 2016 | World Journal of Gastrointestinal Surgery2016，8，11： | 6 |
| 2 | Psychotropic drugs and liver disease:A critical review of pharmacokinetics and liver toxicity显示文摘The liver is the organ by which the majority of sub-stances are metabolized, including psychotropic drugs. There are several pharmacokinetic changes in end-stage liver disease that can interfere with the metabolization of psychotropic drugs. This fact is particularly true in drugs with extensive first--pass metabolism, highly protein bound drugs and drugs depending on phase I hepatic metabolic reactions. Psychopharmacological agents are also associated with a risk of hepatotoxicity. The evidence is insufficient for definite conclusions regarding the prevalence and severity of psychiatric drug-induced liver injury. High-risk psychotropics are not advised when there is pre-existing liver disease, and after starting a psychotropic agent in a patient with hepatic impairment, frequent liver function/lesion monitoring is advised. The authors carefully review the pharmacokinetic disturbances induced by end-stage liver disease and the potential of psychopharmacological agents for liver toxicity. | Diogo Telles-Correia António Barbosa Helena Cortez-Pinto Carlos Campos Nuno B F Rocha Sérgio Machado | 2017 | World Journal of Gastrointestinal Pharmacology and Therapeutics2017，8，1： | 3 |
| 3 | 金龟子绿僵菌分生孢子暴露在B段紫外光下毒力的降低显示文摘The UV-A and UV-B wavelengths of solar radiation may seriously reduce viability of Metarhizium anisopliae conidia,a fungus used extensively in Brazil for insect pest control.The conidial tolerances to UV-A and UV-B radiation were studied for one isolate(IBCB 425) commercially available product produced on rice grains.Aqueous or oil emulsion conidial suspensions were irradiated for 0(control),2,or 3 h using the solar simulator filtered with diacetate filter to remove UV-C radiation which afforded 652 mW·m-2 in the spectral range of 280~370 nm.The UV tolerance was based on conidial germination(viability) and virulence to Diatraea saccharalis larvae.Conidia formulated with oil emulsion had higher survival after 3 h of UV exposure,but the virulence of the conidia previously exposed to 2 h of UV radiation were similar when oil formulated or not.The mortality of D.saccharalis caterpillars exposed to non-UV-irradiated conidia was greater than that of larvae exposed to irradiated conidia,and the LT50 values were lower for the non-irradiated suspensions than for those irradiated.This apparent reduction in virulence was directly related reduction in viability or delay of germination of UV-irradiated conidia. | Edimara A Francisco Drauzio E N Rangel Newton La Scala Jr José C Barbosa Antnia do C B Correia | 2008 | 安徽农业大学学报2008，35，2： | 2 |
| 4 | Stability analysis and improvement of structural index estimation in Euler deconvolution显示文摘 | Barbosa V C F Silva J B C Medeiros W E | 1999 | Geophysics1999，64，1： | 1 |
| 5 | Mechanical behavior and microstructure of high carbon Si- Mn- Cr steel with TRIP effect 显示文摘 | SANTOS D B BARBOSA R De OLIVEIRA P P | 2009 | ISH International2009，49，10： | 1 |
| 6 | Inactivating Microorganism Using a Pulsed Electric Field Continuous Treatment system显示文摘 | QIN B L BARBOSA CNOVAS G V | 1998 | IEEE Trans Indus Applic1998，34，1： | 1 |
| 7 | Making Euler deconvolution applicable to small ground magnetic surveys显示文摘 | Valéria C F Barbosa Joao B C Silva Walter E Medeiros | 2000 | Journal of Applied Geophysics2000，43，1： | 1 |
| 8 | Screening of yeasts for production of xylitol from D-xylose and some factors which affect xylitol yield in Candida guilliermondii显示文摘 | BARBOSA M F S MEDEIROS M B MANCILHA I M | 1988 | Journal of Industrial Microbiology1988，3，： | 1 |
| 9 | Automatic small bowel tumor diagnosis by u?sing multi-scale wavelet-based analysis in wireless cap?sule endoscopy images显示文摘 | Barbosa D C Roupar D B RamosJ C Tavares A C Li?rna C S | 2012 | Biomed Eng Online2012，11，： | 1 |
| 10 | Differential expression of over 60 chromosomal genes in Escherichia coli by constitutive expres- sion of MarA显示文摘 | Barbosa T M Levy S B | 2000 | J Bacheriol2000，182，12： | 1 |
| 11 | Development of a controlled release formulation based on SLN and NLC for topical clotrimazole delivery 显示文摘 | SOUTO E B WISSING S A BARBOSA C M | 2004 | Int J Pharm2004，278，1： | 1 |
| 12 | 3D Euler deconvolution : Theoretical basis for automatically selecting good solutions 显示文摘 | Silva J B C Barbosa V C F | 2003 | Geophysics2003，68，6： | 1 |
| 13 | Osteopathia striata with cranial sclerosis显示文摘 | Barbosa M Perdu B Senra V | 2010 | Acta Med Port2010，23，6： | 1 |
| 14 | Boost current multilevel inverter and its application on single-phase grid-connected photovoltaic systems显示文摘 | Barbosa P G Braga H A C Rodrigues M C B | 2006 | IEEE Transactions on Power Electronics2006，21，4： | 1 |
| 15 | Determination of trace element concentrations in tomato samples at different stages of maturation by ICP OES and ICP-MS following microwave-assisted digestion显示文摘 | BRESSY F C BRITO G B BARBOSA I S | 2013 | Microchemical Journal2013，109，： | 1 |
| 16 | Metabolic effects of L - alanyl - glutamine in burned rats显示文摘 | Barbosa C R Guimaraes S B de Vasconcelos P R | 2006 | Burns2006，32，4： | 1 |
| 17 | 3D gravity inversion through an adaptive-learning procedure显示文摘 | SILVA DIAS F J BARBOSA V C SILVA J B | 2009 | Geophysics2009，74，3： | 1 |
| 18 | Voltage stability probabilistic assessment in composite systems-modeling unsolvability and controllability loss显示文摘 | Anselmo Barbosa Rodrigues Prada R B Maria Da Guia da Silva | 2010 | IEEE Trans on Power Systems2010，25，3： | 1 |
| 19 | Generalized compact gravity inversion显示文摘 | Barbosa V C F Silva J B C | | 0，，01： | 1 |
| 20 | Mapping substrate/film adhesion with contact resonance-frequency atomic force mi croscopy 显示文摘 | Hurley D C Kopycinska Muller M Langlois E D Kos A B Barbosa N | 2006 | Applied Physics Letters2006，89，02： | 1 |
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