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| 1 | Laparoscopic vs open approach to resection of hepatocellular carcinoma in patients with known cirrhosis:Systematic review and meta-analysis显示文摘AIM: To review the currently available literature comparing laparoscopic to open resection of hepatocellular carcinoma(HCC) in patients with known liver cirrhosis.METHODS: A literature search of MEDLINE, EMBASE, and Cochrane databases was conducted. The search terms used included(laparoscopic OR laparoscopy) AND(hepatic or liver) AND(surgery or resection) AND 'hepatocellular carcinoma' AND(cirrhosis or cirrhotic). Furthermore, to widen the search, we also used the 'related articles' section. Studies reporting a comparison of outcomes and methods of open vs laparoscopic hepatic resection for HCC in patients with liver cirrhosis were included. Meta-analysis of results was performed using a random effects model to compute relative risk(RR) and for dichotomous variablesand standard mean differences(SMD) for continuous variables.RESULTS: A total of 420 patients from 4 cohort studies were included in final analysis. Patients undergoing laparoscopic procedures had statistically less blood loss compared to the open cohort, SMD of-1.01(95%CI:-1.23-0.79), P < 0.001, with a reduced risk of transfusion, RR = 0.19(95%CI: 0.09-0.38), P < 0.001. A wider clearance at tumour resection margins was achieved following a laparoscopic approach, SMD of 0.34(95%CI: 0.08-0.60), P = 0.011. No significant difference was noted between laparoscopic and open resection operative times, SMD of-0.15(95%CI: 0.35-0.05), P = 0.142. The overall RR of suffering from postoperative morbidity is 0.25 in favour of the open surgery cohort(95%CI: 0.17-0.37), P < 0.001. Patients under-going laparoscopic surgery had significantly shorter length of stays in hospital compared to the open cohort, SMD of-0.53(95%CI:-0.73 to-0.32), P < 0.001.CONCLUSION: This review suggests that laparoscopic resection of hepatocellular carcinoma in patients with cirrhosis is safe and may provide improved patient outcomes when compared to the open technique. | Ahmed Twaij Philip H Pucher Mikael H Sodergren Tamara Gall Ara Darzi Long R Jiao | 2014 | World Journal of Gastroenterology2014，20，25： | 16 |
| 2 | Treatment of idiopathic membranous nephropathy with the combination of steroids,tacrolimus and mycophenolate mofetil:results of a pilot study显示文摘 | Ballarin J Poveda R Ara J | 2007 | Nephrol Dial Transplant2007，22，11： | 1 |
| 3 | Microindentation can discriminate between damaged and intact human bone tissue显示文摘 | E Dall'Ara R Schmidt P Zysset | 2012 | Bone2012，50，4： | 1 |
| 4 | In vitro antimicrobial activity of silicone oil against endophthalmitis causing agents显示文摘 | Ozdamar A Aras C Ozturk R | 1999 | Retina1999，19，2： | 1 |
| 5 | Efficacy of continuous glucose monitoring system to detect unrecognized hypoglycemia in children and adolescents with type 1 diabetes显示文摘 | MAIA F F ARA(U)JO L R | 2005 | Arq Bras Endocrinol Metabol2005，49，4： | 1 |
| 6 | Feasibility of extraperitoneal laparoscopic para-aortic and com m on iliac lym phadenectom y显示文摘 | NAGAO S FUJIW ARA K KAGAW A R | 2006 | Gynecol Oncol2006，103，2： | 1 |
| 7 | An empirical assessment of ecological footprint calculations for Malaysia 显示文摘 | Ara B R | 2009 | Resources Conservation and Recycling2009，53，： | 1 |
| 8 | Simple rigid plastic model for seismic tilting of rigid walls 显示文摘 | Siddharthan R Ara A Norris G M | 1989 | Journal of Structural Engineering ASCE1989，118，： | 1 |
| 9 | Recurrent lentigo maligna as amelanotic lentigo maligna melanoma 显示文摘 | Ara M MaiUo C Martin R | 2002 | JEur Acad Derm Venereol2002，16，5： | 1 |
| 10 | Industrial application of AISI 4340 steels treated in cathodic cage plasma nitriding technique显示文摘 | RIBEIRO K J B de SOUSA R R M de ARAJO F O | 2008 | Materials Science and Engineering:2008，479，： | 1 |
| 11 | A robust automatic phase-adjustment method for fi-nancial forecasting显示文摘 | De ARA JO R | 2011 | Knowledge-based Systems2011，27，3： | 1 |
| 12 | Modified Microelectrodes and Multivariate Calibration for Flow Injection Amperometric Simultaneous Determination of Ascorbic Acid,Dopamine,Epinephrine and Dipyrone显示文摘 | Angnes L Araújo M C U | 2000 | Analyst2000，125，11： | 1 |
| 13 | Hybrid intelligent methodology to design translationinvariant morphological operators for Brazilian stock market prediction显示文摘 | De ARA JO R | 2010 | Neural Networks2010，23，10： | 1 |
| 14 | Adsorption of polycyclic aromatic hydrocarbons(PAHs)from isooctane solutions by mesoporous molecular sieves:influence of the surface acidity显示文摘 | Araújo R S Azevedo D C S Cavalcante Jr C L | 2008 | Microporous and Mesoporous Materials2008，108，： | 1 |
| 15 | Optical coherence tomography for evaluation of anatomical changes in the cornea after laser in situ keratomileusis显示文摘 | Usttmdag C Bahcecioglu H Ozdamar A Aras C Yildirim R Ozkan S | 2000 | J Cataract Refract Surg2000，26，10： | 1 |
| 16 | Phase II study of a combination of irinotecan and S-1 in patien ts with advanced gastric cancer(OGSG0002)显示文摘 | U edo N Narah ara H Ishihara R | 2007 | Oncology2007，73，12： | 1 |
| 17 | Asian dust:seasonal transport to the Hawaiian Islands显示文摘 | Parrington J R Zoller W H Aras N K | 1983 | Science (Washington DC)1983，246，： | 1 |
| 18 | Diagonalization of matrices over regular rings显示文摘 | ARA P GOODEARL K R OMEARA K C | 1997 | Linear Algebra Appl1997，265，： | 1 |
| 19 | Finite-element modeling and optimization-based parameter extraction algorithm for NPT-IGBTS显示文摘 | CHIBANTE R ARA(U)JO A CARVALHO A | | 0，，05： | 1 |
| 20 | Potassium-modified Mg(NH2)2/2Li H system for hydrogen storage显示文摘 | Wang J H Liu T Wu G T Li W Liu Y F Moysés Araújo C Scheicher R H Blomqvist A Ahuja R Xiong Z T Yang P Gao M X Pan H G Chen P | 2009 | Angewandte Chemie International Edition2009，48，： | 1 |
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