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| 1 | Pre-osteoblastic MC3T3-E1 cells promote breast cancer growth in bone in a murine xenograft model显示文摘The bones are the most common sites of breast cancer metastasis. Upon arrival within the bone microenvironment, breast cancer cells coordinate the activities of stromal cells, resulting in an increase in osteoclast activity and bone matrix degradation. In late stages of bone metastasis, breast cancer cells induce apoptosis in osteoblasts, which further exacerbates bone loss. However, in early stages, breast cancer cells induce osteoblasts to secrete inflammatory cytokines purported to drive tumor progression. To more thoroughly evaluate the role of osteoblasts in early stages of breast cancer metastasis to the bones, we used green fluorescent protein-labeled human breast cancer cell lines MDA-MB-231 and MDA-MB-435, which both induce osteolysis after intra-femoral injection in athymic mice, and the murine pre-osteoblastic cell line MC3T3-E1 to modulate osteoblast populations at the sites of breast cancer metastasis. Breast cancer cells were injected directly into the femur with or without equal numbers of MC3T3-E1 cells. Tumors grew significantly larger when co-injected with breast cancer cells and MC3T3-E1 cells than injected with breast cancer cells alone. Osteolysis was induced in both groups, indicating that MC3T3-E1 cells did not block the ability of breast cancer cells to cause bone destruction. MC3T3-E1 cells promoted tumor growth out of the bone into the extraosseous stroma. These data suggest that breast cancer cells and osteoblasts communicate during early stages of bone metastasis and promote tumor growth. | Thomas M. Bodenstine Benjamin H. Beck Xuemei Cao Leah M. Cook Aimen Ismail J. Kent Powers Andrea M. Mastro Danny R. Welch | 2011 | Chinese Journal of Cancer2011，30，3： | 5 |
| 2 | Object-oriented image analysis for mapping shrub encroachment from 1937 to 2003 in southern New Mexico显示文摘 | Andrea S. Laliberte Albert Rango Kris M. Havstad Jack F. Paris Reldon F. Beck Rob McNeely Amalia L. Gonzalez | 2004 | Remote Sensing of Environment2004，，1： | 3 |
| 3 | Object-oriented image analysis for mapping shrub encroachment from 1937 to 2003 in southern New Mexico显示文摘 | Andrea S. Laliberte Albert Rango Kris M. Havstad Jack F. Paris Reldon F. Beck Rob McNeely Amalia L. Gonzalez | 2004 | Remote Sensing of Environment2004，，1： | 2 |
| 4 | Virtual network embedding: a survey 显示文摘 | Fischer Andreas Botero Juan Felipe Till Beck Michael | 2013 | IEEE Commu- nications Surveys and Tutorials2013，15，4： | 1 |
| 5 | Prediction of Service Life for Vacuum Insulation Panels with Fumed Silica Kernel and Foil Cover显示文摘 | Hubert Schwab Ulrich Heinemann Andreas Beck | 2005 | Journal of Thermal Envelope and Building Science2005，28，4： | 1 |
| 6 | Development and evaluation of orally disintegrating tablets (ODTs) containing Ibuprofen granules prepared by hot melt extrusion显示文摘 | Andreas Gryczke Silke Schminke Mohammed Maniruzzaman Julien Beck Dennis Douroumis | 2011 | Colloids and Surfaces B: Biointerfaces2011，，2： | 1 |
| 7 | Dependence of Thermal Conductivity on Water Content in Vacuum Insulation Panels with Fumed Silica Kernels显示文摘 | HUBERT SCHWAB ULRICH HEINEMANN ANDREAS BECK | 2005 | Journal of Thermal Envelope and Building Science2005，28，4： | 1 |
| 8 | Different neural systems adjust motor behavior in response to reward and punishment显示文摘 | Jana Wrase Thorsten Kahnt Florian Schlagenhauf Anne Beck Michael X. Cohen Brian Knutson Andreas Heinz | 2007 | Neuroimage2007，，4： | 1 |
| 9 | Improved Outcomes With Quality Improvement Interventions in Pediatric Inflammatory Bowel Disease显示文摘 | Charles M. Samson Pamela Morgan Elizabeth Williams Lee Beck RicJunette Addie-Carson Stacy McIntire Andrea Booth Eduardo Mendez Carolyn Luzader Gitit Tomer Shehzad Saeed Edward Donovan John Bucuvalas Lee A. Denson | 2012 | Journal of Pediatric Gastroenterology and Nutrition2012，，6： | 1 |
| 10 | Prediction of Service Life for Vacuum Insulation Panels with Fumed Silica Kernel and Foil Cover显示文摘 | Hubert Schwab Ulrich Heinemann Andreas Beck | 2005 | Journal of Thermal Env & Bldg Sci2005，28，4： | 1 |
| 11 | Dependence of Thermal Conductivity on Water Content in Vacuum Insulation Panels with Fumed Silica Kernels显示文摘 | Hubert Schwab Ulrich Heinemann Andreas Beck | 2005 | Journal of Thermal Env & Bldg Sci2005，28，4： | 1 |
| 12 | Permeation of Different Gases through Foils Used as Envelopes for Vacuum Insulation Panels显示文摘 | Hubert Schwab Ulrich Heinemann Andreas Beck | 2005 | Journal of Themal Env & Bldg Sci2005，28，4： | 1 |
| 13 | Sequence analysis and expression of the attachment and fusion proteins of Canine distemper virus wild - type strain A75/17 显示文摘 | Pascal Cherpillod Karin Beck Andreas Zurbriggen | 1999 | J Virol1999，73，3： | 1 |
| 14 | Phytochelatins are Synthesized by Two Vacuolar Serine Carboxypeptidases in Saccharomyces Cerevisiae显示文摘 | JANA WU NSCHMANN ANDREAS BECK | 2007 | FEES Letters2007，581，： | 1 |
| 15 | Comparison of autoantibody‐positive and autoantibody‐negative pediatric participants enrolled in the T1D Exchange clinic registry (在1型糖尿病交流中心临床登记的自身抗体阳性与自身抗体阴性的儿科参与者的比较)显示文摘 | Andrea Gerard‐Gonzalez Stephen E. Gitelman Peiyao Cheng Stephanie N. Dubose Kellee M. Miller Beth A. Olson Maria J. Redondo Andrea K. Steck Roy W. Beck | 2013 | Journal of Diabetes2013，，2： | 1 |
| 16 | Prediction of Service Life for Vacuum Insulation Panels with Fumed Silica Kernel and Foil Cover显示文摘 | Hubert Schwab Ulrich Heinemann Andreas Beck | 2005 | Journal of Thermal Envelope and Building Science2005，28，4： | 1 |
| 17 | PCM-facade-panel for daylighting and room heating显示文摘 | Helmut Weinlader Andreas Beck Jochen Fricke | 2005 | Solar Energy2005，78，： | 1 |
| 18 | The distribution of ascus types and photobiontal selection in Lecanoromycetes (Ascomycota) against the background of a revised SSU nrDNA phylogeny显示文摘 | Derek Per?oh Andreas Beck Gerhard Rambold | 2004 | Mycological Progress2004，，2： | 1 |
| 19 | Prediction of Service Life for Vacuum Insulation Panels with Fumed Sili- ca Kernel and Foil Cover 显示文摘 | Hubert Schwab Ulrich Heinemann Andreas Beck | 2005 | Journal of Thermal Envelopeand Building Science2005，28，4： | 1 |
| 20 | Noncommuting multidimensional realization theory: Minimality, reachability, and observability显示文摘 | Beck C L D'Andrea R | 2004 | IEEE Transactions on Automatic Control2004，49，10： | 1 |
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