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54篇 您的检索式:作者名="Almofti"
    题名 作者 年代 出处 被引量
1双向电泳-质谱技术筛选肝癌血清标记物显示文摘采用双向电泳-质谱技术筛选肝癌特异的血清蛋白标记物,以利于肝癌的早期诊断和治疗.肝癌、肝炎和正常三组各20例血清先采用超声、高丰度蛋白去除、脱盐预处理以优化双向电泳,图像分析三组血清图谱寻找差异点,基质辅助激光解吸飞行时间质谱对差异点进行鉴定.结果显示,通过样品预处理,血清上样体积平均增加3~4倍,参考胶点数由218个增至332个,白蛋白和免疫球蛋白明显减弱,水平条带明显减少.图谱比较所得37个差异点,经鉴定为7种蛋白.与正常组比较,转铁蛋白、甲状腺素运载蛋白在肝炎和肝癌组低表达,α-1抗胰蛋白酶、凝聚素、铜蓝蛋白、触珠蛋白在肝炎和肝癌组均高表达.α-1抗胰蛋白酶在肝癌组较肝炎组高表达,而热休克蛋白27只在肝癌组表达.上述结果提示,双向电泳-质谱技术可发现肝癌发生发展过程中血清蛋白表达谱质或量的变化,从而为肝癌的早期诊断及治疗奠定基础.冯钜涛 刘银坤 MOHAMAD RADWAN ALMOFTI 代智 周海君 宋海燕 陆豪杰 汤钊猷 2005生物化学与生物物理进展2005,32,7:15
2Reduction of atherosclerosis in cholesterol-fed rabbits and decrease of expressions of intracellular adhesion molecule-1 and vascular endothelial growth factor in foam cells by a water-soluble fraction of Polygonum multiflorum显示文摘Yang PY Almofti MR Lu L Kang H Zhang J Li TJ Rui YC Sun LN Chen WS 2006第二军医大学学报2006,27,6:7
3Reduction of atherosclerosis in cholesterol-fed rabbits and decrease of expressions of intracellular adhesion molecule -1 and vascular ehdothelal growth factor in foam cells by a water-soluble fraction of Polygonum multiflorm显示文摘Yang PY Almofti MR Lu L 2005J Pharm Sci2005,99,3:1
4Possible role of stromal cell-derived factor-1/CXCR4 signaling on lymph node metastasis of oral squamous cell carcinoma显示文摘Uchida D Begum NM Almofti A 2003Exp Cell Res2003,290,2:1
5Possible role of stromal-cell-derived factor-1/CXCR4 signaling on lymph node metastasis of oral squamoas cell carcinoma显示文摘Uchida D Begum NM Almofti A 2003Exp Cell Res2003,290,2:1
6The clinicopathological significance of the expression of CXCR4 protein in oral squamous cell carcinoma 显示文摘Almofti A Uchida D Begum NM 2004Int J Oncol2004,25,1:1
7The elinieopathologieal significance of the expression of CXCR4 protein in oral squamous cell carcinoma 显示文摘Almofti A Uehida D Begum N M 2004Int J Oncol2004,25,1:1
8Possible role of stromal-cell-derived factor-1/CXCR4 signaling on lymph node metastasis of oral squamous cell carcinoma 显示文摘Uchida D Begum NM Almofti A 2003Exp Cell Res2003,290,2:1
9Reduction of atherosclerosis in cholesterol-fed fabbits and decrease of expressions of intracellular adhesion molecule-1 and vascular endothelial growth factor in foam cells by a water-solublefraction of Polygonum multiflorum显示文摘Peng Y Y Almofti M R Ling L 2005J Pharmacol Sci2005,99,:1
10Possible role of stromal-cell-derived factor-1/CXCR4 signaling on lymph node metastasis of oral squamous cell carcinoma 显示文摘UCHIDA D BEGUM N M ALMOFTI A 2003Exp Cell Res2003,290,:1
11Cationic liposome-mediated gene delivery:biophysical study and mechanism of internalization显示文摘Almofti MR Harashima H Shinohara Y 2003Arch Biochem Biophys2003,410,2:1
12Comparativeanalysis of the proteome of left ventricular heart ofarteriosclerosis in rat 显示文摘Huang Z Yang P Radwan Almofti M 2004Life Sci2004,75,26:1
13Reduction of atherosclerosis in cholesterol-fed rabbits and decrease of expressions of intracellular adhesion molecule-1 and vascular endothelial growth factor in form ceils by a water-soluble fraction of Polygonum multi florum 显示文摘Yang P Y Almofti M R Lu L 2005J Pharmacol Sci2005,99,3:1
14Reduction of atherosclerosis in cholesterol- fed rabbits and de- crease of expressions of intraeellular adhesion molecule - 1 and vascular endothelial growth factor in foam cells by a water - solu- ble fi'action of Polygonum muhiflorum 显示文摘Peng - Yuan Yang Mohamad Radwan Almofti Ling Lu etal 2005J Pharmacol Sei2005,99,3:1
15Comparative analysis of the proteome of left ventricular heart of arteriosclerosis in rats显示文摘 Yang PY Almofti MR 2004Life Sci2004,75,26:1
16Reduction of atherosclerosis in cholesterol-fed rabbits and decrease of expressions of intracellular adhesion molecule-1 and vascular endothelial growth factor in foam cells hy a water-soluble fraction of Polygonum multiflorum 显示文摘YANG P Y ALMOFTI M R LU L 2005J Pharmacol Sci2005,99,3:1
17Comparative analysis of the proteome of left ventricular heart of arteriosclerosis in rat显示文摘Huang ZY Yang PY Almofti MR 2004Life Sci2004,75,26:1
18Possible role of stromal-cell-derived factor-1/CXCR4 signaling on lymph node metastasis of oral squamous cell carcinoma 显示文摘Uchida D Begum NM Almofti A 2003Exp Cell Res2003,290,2:1
19Reduction of atherosclerosis in cholesterol-fed rabbits and decrease of expressions of intracellular adhesion molecule-1 and vascular endothelial growth factor in foam ceils by a water-solution fraction of Polygonum multiflorum显示文摘Yang P Y Almofti M R Lu L 2005J Pharmacol Sci2005,99,3:1
20The clinicopatho- logical significance of the expression of CXCR4 protein in o- ral squamous cell carcinoma 显示文摘Almofti A Uehida D Begum NM 2004Int J Oncol2004,25,1:1
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