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	题名	作者	年代	出处	被引量
1	Helicobacter pylori-induced inflammation and epigenetic changes during gastric carcinogenesis显示文摘The sequence of events associated with the development of gastric cancer has been described as 'the gastric precancerous cascade'. This cascade is a dynamic process that includes lesions, such as atrophic gastritis, intestinal metaplasia and dysplasia. According to this model, Helicobacter pylori(H. pylori) infection targets the normal gastric mucosa causing non-atrophic gastritis, an initiating lesion that can be cured by clearing H. pylori with antibiotics or that may then linger in the case of chronic infection and progress to atrophic gastritis. The presence of virulence factors in the infecting H. pylori drives the carcinogenesis process. Independent epidemiological and animal studies have confirmed the sequential progression of these precancerous lesions. Particularly long-term follow-up studies estimated a risk of 0.1% for atrophic gastritis/intestinal metaplasia and 6% in case of dysplasia for the long-term development of gastric cancer. With this in mind, a better understanding of the genetic and epigenetic changes associated with progression of the cascade is critical in determining the risk of gastric cancer associated with H. pylori infection. In this review, we will summarize some of the mostrelevant mechanisms and focus predominantly but not exclusively on the discussion of gene promoter methylation and mi RNAs in this context.	Manuel A Valenzuela Jimena Canales Alejandro H Corvalán Andrew FG Quest	2015	World Journal of Gastroenterology2015，21，45：	33
2	Evidence-based medicine:watching out for its friends显示文摘	Brody H Miller FG Bogdan LE	2005	Perspect Biol Med2005，48，4：	1
3	Pretreatment evalu- ation of prostate cancer:role of MR imaging and IH MR spectros- copy显示文摘	Claus FG Hricak H Hattery RR	2004	Radiographics2004，24，1：	1
4	Investigation of the role of prolactin in the development and function of the lacrimal and harderian glands using genetically modified mice显示文摘	McClellan KA Robertson FG Kindblom J Wennbo H Tornell J Bouchard B	2001	Invest Ophthalmol Vis Sci2001，42，1：	1
5	Differentiation-independent retinoid induction of folate receptor type beta,a potential tumor target in myeloid leukemia显示文摘	Wang H Zheng X Behm FG	2000	Blood2000，96，3：	1
6	Simultaneous immobilization protein microarrays by a micro stamper with back-filling reservoir 显示文摘	Lin SC Tseng FG Huang H M	2004	Sens Actu B Chem2004，99，1：	1
7	Preclinical evaluation of gemcitabine/paclitaxel-interactions in human bladder cancer lines显示文摘	Perabo FG Lindner H Schmidt D	2003	Anticancer Res2003，23，6：	1
8	PTEN signaling pathways in melanoma 显示文摘	Wu H Goel V Haluska FG	2003	Oncogene2003，22，20：	1
9	Second-generation antipsychotic agents in the treatment of acute mania: a systematic review and recta-analysis of randomized controlled trials显示文摘	Scherk H Pajonk FG Leucht S	2007	Arch Gen Psychiat2007，64，4：	1
10	Peripheral nerve lesions:the neuropharmacological outlook显示文摘	Kerkhoff H Jennekens FG	1993	Clin Neurol Neurosurg1993，，：	1
11	In vitro proliferation,expansion,and differentiation of a CD34^+ cell-enriched Hematopoietic cell population from human umbilical cord blood in response to recombinant cytokines显示文摘	Patricia FG Margarita RT Mayani H	2002	Archi Med Rese2002，33，：	1
12	Gambogenic acid induced apoptosis referred to Erkl/2 and p38 in hepatic cell line HepG2 显示文摘	Yan FG Wang M Chen H	2012	Environmental Toxicology and Pharmacology2012，33，2：	1
13	Ranibizumab for predominantly classic neovascular age- related macular degeneration: subgroup analysis of first-year ANCHOR results显示文摘	Kaiser PK Brown DM Zhang K Hudson HL Holz FG Shapiro H	2007	Am J Ophthalmo12007，144，6：	1
14	The role of transposable elements in the regulation of IFN-lambdal gene expression 显示文摘	Thomson S J Goh FG Banks H	2009	Pro Natl Acad Sci U S A2009，106，11：	1
15	Submacular fluid after encircling buckle surgery for inferior macula-off retinal detachment in young patients显示文摘	Abouzeid H Becker K Holz FG	2009	Ada Ophthalmol2009，87，1：	1
16	Intraductal papillary neoplasm of the bile duct: a biliary equivalent to intradnctal papillary mucinous neoplasm of the pancreas? 显示文摘	Rocha FG Lee H Katabi N	2012	Hepatology2012，56，：	1
17	Submacular fluid after encircling buckle surgery for inferior macula-off retinal detachment in young patients 显示文摘	Abouzeid H Becker K Holz FG	2009	Aeta Ophthalmol2009，87，：	1
18	Upper and lower urinary tract e- valuation of 104 patients with myelomeningocele without adequate uro- logical management 显示文摘	Bruschini H Almeida FG Srougi M	2006	World J Urol2006，24，2：	1
19	The role of transposable elements in the regulation of IFN-lambda1 gene expression显示文摘	Thomson SJ Goh FG Banks H	2009	Proc Natl Acad Sci USA2009，106，11：	1
20	PTEN signaling pathways inmelanoma显示文摘	Wu H Goel V Haluska FG	2003	Oncogene2003，22，20：	1

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