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| 1 | 前庭功能损失后电动头脉冲试验中水平前庭眼反射的恢复普遍存在显示文摘目的:对急性单侧外周前庭功能损失的患者使用机动化的头脉冲试验量化前庭功能的恢复,并把这些结果与其他体征和症状相比较。方法:使用机动化头脉冲旋转仪记录30例突发单侧前庭功能障碍的患者平均在发生后3d(前期)的潜在的水平前庭眼反射(VOR),20例患者平均3个月后(后期)继续测量。计算VOR增益和不对称(珚x±s)。结果:从前期的患侧增益0.49±0.21到后期的0.79±0.23(P=0.0000)有高度显著改善。各自的不对称从(32±18)%到(12±14)%(P=0.0002)也有高度显著改善。至少80%的患者增益或不对称恢复。后期的高症状评分与低增益(P=0.043)和高不对称(P=0.018)有相关性。结论:用机动化的头脉冲旋转仪来测量减少的水平VOR增益,突发单侧前庭功能损失后至少部分恢复。除了眼震的传统评价,头脉冲试验的反应为前庭损失的严重程度和恢复提供了有价值的信息。 | TOPI JUTILA HEIKKI AALTO TIMO P.HIRVONEN 张甦琳 孔维佳 | 2014 | 临床耳鼻咽喉头颈外科杂志2014，28，8： | 2 |
| 2 | Impacts of common factors of life style on serum liver enzymes显示文摘AIM: To investigate the impacts of gender, age and factors of life style(alcohol, overweight, coffee and smoking) on serum liver enzymes.METHODS: Serum alanine aminotransferase(ALT) and gamma-glutamyltransferase(GGT) were measured from 6269 apparently healthy individuals(2851 men, 3418 women, mean age 45 ± 12 years, range 25-74 years) in a national cross-sectional health survey. All subjects underwent detailed clinical examinations and interviews including the amount and pattern of alcoholuse, coffee consumption and smoking habits. RESULTS: In this population with a mean ± SD alcohol consumption of 65 ± 105 g/wk and body mass index(BMI) of 26.1 ± 4.3 kg/m2, both ALT and GGT were significantly influenced by alcohol use(P < 0.001) and BMI(P < 0.001), whereas smoking increased only GGT(P < 0.001). A significant effect of age on ALT was seen in men(P < 0.001) whereas not in women. Significant two-factor interactions of alcohol use in men were observed with age(ALT: P < 0.01; GGT: P < 0.001) and BMI(GGT: P < 0.05). For ALT, a significant interaction also occurred between BMI and age(P < 0.005). In contrast, women showed significant interactions of alcohol use with BMI(GGT: P < 0.05), smoking(GGT: P < 0.001), and coffee consumption(GGT: P < 0.001). CONCLUSION: Life-style associated changes in liver enzymes may reflect health risks, which should be considered in the definition of normal limits for liver enzymes. | Joanna Danielsson Pivikki Kangastupa Tiina Laatikainen Mauri Aalto Onni Niemel | 2014 | World Journal of Gastroenterology2014，20，33： | 2 |
| 3 | Requirement of a Homolog of Glucosidase Ⅱ β-Subunit for EFR-Mediated Defense Signaling in Arabidopsis thaliana显示文摘 | Nina von Numers Mantas Survila Markku Aalto Martine Batoux Pekka Heino E. Tapio Palva Jing Li | 2010 | Molecular Plant2010，3，4： | 2 |
| 4 | Prolonged central muopioid receptor occupancy after single and repeated nalmefene dosing显示文摘 | Ingman K Hagelberg N Aalto S et a1 | 2005 | Neuro psychopharmacology2005，30，12： | 1 |
| 5 | Laboratory markers of systemic inflammation as predictors of bloodstream infection in acutely ill patients admitted to hospital in medical emergency 显示文摘 | Aalto H Takala A Kautiainen H | 2004 | Eur Clin Microbiol Infect Dis2004，23，9： | 1 |
| 6 | Depression and heavy drinking oc- casions: A cross-sectional general population study 显示文摘 | Levola J Holopainen A Aalto M | 2011 | Addictive Behaviors2011，36，： | 1 |
| 7 | Effects of sevoflurane,propofol,and advunct nitrous oxide on regional cerebral blood flow,oxygen consumption,and blood volume in humans显示文摘 | KAISTI KK LNGSV VW AALTO S | 2003 | Anesthesiology2003，99，6： | 1 |
| 8 | Task assignment in a heteroge- neous server farm with switching delays and general energy- aware cost structure显示文摘 | Hyytia E Righter R Aalto S | 2014 | Performance Evaluation2014，75，6： | 1 |
| 9 | Effects of a 902Mhz mobile phone on cerebral blood flow in humans: a PET study显示文摘 | HAARALA C AALTO S HAUTZEL H | 2003 | Neuroreport2003，14，： | 1 |
| 10 | PET amyloid ligand[11C]PIB uptake is increased in mild cognitive impairment显示文摘 | Kemppainen NM Aalto S Wilson IA | | 0，，19： | 1 |
| 11 | DNA copy number losses in human neoplasms显示文摘 | Knuutila S Aalto Y Autio K | 2000 | Am J Pathol2000，157，2： | 1 |
| 12 | Observations of ultrafine aerosol particle formation and growth in boreal forest 显示文摘 | M?kel? J M Aalto P Jokinen V | 1997 | Geophysical Research Letters1997，24，10： | 1 |
| 13 | Voxel-based analysis of PET amyloid ligand PIB uptake in Alzheimer dis?ease 显示文摘 | Kemppainen N Aalto S Wilson I | 2006 | Neurology2006，67，： | 1 |
| 14 | Semi-continuous gas and inorganic aerosol measurements at a Finnish urban site: comparisons with filters, nitrogen in aerosol and gas phases, and aerosol acidity显示文摘 | Makkonen U. Virkkula A. M?ntykentt? J. Hakola H. Keronen P. Vakkari V. Aalto P. P | 2012 | Atmospheric Chemistry and Physics2012，，272： | 1 |
| 15 | Sub-μs switching time in silicon-on-insulator Mach-Zehnder thermooptic switch显示文摘 | Harjanne M Kapulainen M Aalto T | 2004 | IEEE Photonics Technol Lett2004，16，： | 1 |
| 16 | Factors affecting sample preparation in the gas chromatographic determination of plant sterols in whole wheat flour显示文摘 | Toivo J Lampi A M Aalto S | 2000 | Food Chemistry2000，68，2： | 1 |
| 17 | Depressionis associated with a poorer outcome of lumbar spinal stenosissurgery显示文摘 | SINIKALLIO S AALTO T AIRAKSINEN O | 2011 | Spine2011，36，8： | 1 |
| 18 | Ketamine dose not decrease striatal dopamine D2 receptor binding in man显示文摘 | Aalto S Hirvonen J Kajander J | 2002 | Psychopharmacology2002，164，4： | 1 |
| 19 | Prolonged central mu-opioid receptor occupancy after single and repeated nalmefene dosing显示文摘 | Ingman K Hagelberg N Aalto S | 2005 | Neuropsychopharmacology2005，30，12： | 1 |
| 20 | PET amyloid li?gand PIB uptake is increased in mild cognitive impair?ment 显示文摘 | Kemppainen NM Aalto S Wilson lA | 2007 | Neurology2007，68，： | 1 |
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