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| 1 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017,16,6: | 8 |
| 2 | Risk for emerging bipolar disorder, variants, and symptoms in children with attention deficit hyperactivity disorder, now grown up显示文摘AIM: To determine the prevalence of bipolar disorder(BD) and sub-threshold symptoms in children with attention deficit hyperactivity disorder(ADHD) through 14 years' follow-up, when participants were between 21-24 years old.METHODS: First, we examined rates of BD type Ⅰ?and Ⅱ diagnoses in youth participating in the NIMH-funded Multimodal Treatment Study of ADHD(MTA). We used the diagnostic interview schedule for children(DISC), administered to both parents(DISC-P) and youth(DISCY). We compared the MTA study subjects with ADHD(n = 579) to a local normative comparison group(LNCG, n = 289) at 4 different assessment points: 6, 8, 12, and 14 years of follow-ups. To evaluate the bipolar variants, we compared total symptom counts(TSC) of DSM manic and hypomanic symptoms that were generated by DISC in ADHD and LNCG subjects. Then we sub-divided the TSC into pathognomonic manic(PM) and non-specific manic(NSM) symptoms. We compared the PM and NSM in ADHD and LNCG at each assessment point and over time. We also evaluated the irritability as category A2 manic symptom in both groups and over time. Finally, we studied the irritability symptom in correlation with PM and NSM in ADHD and LNCG subjects.RESULTS: DISC-generated BD diagnosis did not differ significantly in rates between ADHD(1.89%) and LNCG 1.38%). Interestingly, no participant met BD diagnosis more than once in the 4 assessment points in 14 years. However, on the symptom level, ADHD subjects reported significantly higher mean TSC scores: ADHD 3.0; LNCG 1.7; P < 0.001. ADHD status was associated with higher mean NSM: ADHD 2.0 vs LNCG 1.1; P < 0.0001. Also, ADHD subjects had higher PM symptoms than LNCG, with PM means over all time points of 1.3 ADHD; 0.9 LNCG; P = 0.0001. Examining both NSM and PM, ADHD status associated with greater NSM than PM. However, Over 14 years, the NSM symptoms declined and changed to PM over time(df 3, 2523; F = 20.1; P < 0.0001). Finally, Irritability(BD DSM criterion-A2) rates were significantly higher in ADHD than LNCG(χ2 = 122.2, P < 0.0001), but irritability was associated more strongly with NSM than PM(df 3, 2538; F = 43.2; P < 0.0001).CONCLUSION: Individuals with ADHD do not appear to be at significantly greater risk for developing BD, but do show higher rates of BD symptoms, especially NSM. The greater linkage of irritability to NSM than to PM suggests caution when making BD diagnoses based on irritability alone as one of 2(A-level) symptoms for BD diagnosis, particularly in view of its frequent presentation with other psychopathologies. | Ahmed Z Elmaadawi Peter S Jensen L Eugene Arnold Brooke SG Molina Lily Hechtman Howard B Abikoff Stephen P Hinshaw Jeffrey H Newcorn Laurence Lee Greenhill James M Swanson Cathryn A Galanter | 2015 | World Journal of Psychiatry2015,5,4: | 3 |
| 3 | Rotational relaxation measurements of laser excited Hydrogen fluoride显示文摘 | Peterson L M Lindgulst G H Arnold C B | 1974 | J Chem Phys1974,61,8: | 2 |
| 4 | Computational method to reduce the search space for directed protein evolution显示文摘 | Mayo S L Arnold F H | 2001 | Proc Natl Acad Sci USA2001,98,: | 1 |
| 5 | Temperature-insensitive near-infrared spectro scopic measurement of glucose in aqueous solutions显示文摘 | Hazen Kevin H Arnold Mark A Small Gary W | 1994 | Applied Spectroscopy1994,48,4: | 1 |
| 6 | Early management in poor grade aneurysm patients显示文摘 | Nowak G Schwachenwald R Arnold H | 1994 | Acta Neurochir(Wien)1994,126,1: | 1 |
| 7 | Cytokin(IJ-8,IJ-6,TNF-alpha) and soluble TNF receptor-I release from human peripheral blood mononuclear cells after respiratory syncytial virus infection显示文摘 | Arnold R Konig B Galatti H | 1995 | Immunology1995,85,3: | 1 |
| 8 | Serum zinc correlates with parent-and teacher-rated inattention in children with attention-deficit/hyperactivity disorder显示文摘 | Arnold LE Bozzolo H Hollway J | 2005 | Child Adolesc Psychopharmacol2005,15,4: | 1 |
| 9 | Myostatin knockout in mice increases myogenesis and decreases adipogenesis 显示文摘 | Lin J Arnold H B Della- fera M A | 2002 | Biochem Biophys Res Commun2002,291,3: | 1 |
| 10 | Intrasurgical pancreas cytology显示文摘 | Schramm H Urban H Arnold F | 2002 | Pancreas2002,24,2: | 1 |
| 11 | The coordinate regulation of the p53 and mTOR pathways in cells显示文摘 | Feng Z Zhang H Arnold J | 2005 | Proc Natl Acad Sci USA2005,102,: | 1 |
| 12 | Dorsiflexor and plantar flexor muscle fatigue decreases postural control显示文摘 | JOYCE C J PERRIN D H ARNOLD B L | 2001 | J Athl Train2001,36,: | 1 |
| 13 | Outdoor aging of wood-based pan- els and correlation with laboratory aging: Part 2 显示文摘 | Okkonen E Arnold Bryan H River | 1996 | Forest Products Journal1996,46,3: | 1 |
| 14 | Interleukin-8, inter leukin-6, and soluble tumour necrosis factor receptor type I re- lease from a human pulmonary epithelial cell line (A549) exposed to respiratory syncytial virus显示文摘 | Arnold R Humbert B Werchau H | 1994 | Immunology1994,82,1: | 1 |
| 15 | High - frequency oscillatory ventilation in pediatric patients显示文摘 | Priebe G P Arnold J H | 2001 | Respir Care Clin N Am2001,7,: | 1 |
| 16 | Chemokines direct endothe- lial progenitors into tumor neovessels 显示文摘 | Spring H Schiller T Arnold B | 2005 | Proc Nail Aead Sei U S A2005,102,18: | 1 |
| 17 | A comparison of culture-positive and culture-negative healthcare-associated pneumonia显示文摘 | Labelle A J Arnold H Reichley R M | 2010 | Chest2010,137,5: | 1 |
| 18 | Optimizing non-natural protein function with directed evolution显示文摘 | Brustad E M Arnold F H | 2010 | Curr Opin Chem Biol2010,15,2: | 1 |
| 19 | Serum amyloM P and cardiovascular disease in older men and women:results from the Cardiovascular Health Study显示文摘 | Jenny N S Arnold A M Kuller L H | | 0,,02: | 1 |
| 20 | Dispersion of Air Pollution&Penetration into the Local Environment-DAPPLE显示文摘 | Arnold S J ApSimon H Barlow J | | 0,,: | 1 |